KEGG   Equus asinus (ass): 106846006
Entry
106846006         CDS       T04645                                 
Symbol
MAPK11
Name
(RefSeq) mitogen-activated protein kinase 11 isoform X1
  KO
K04441  p38 MAP kinase [EC:2.7.11.24]
Organism
eai  Equus asinus (ass)
Pathway
eai01522  Endocrine resistance
eai04010  MAPK signaling pathway
eai04015  Rap1 signaling pathway
eai04068  FoxO signaling pathway
eai04071  Sphingolipid signaling pathway
eai04114  Oocyte meiosis
eai04148  Efferocytosis
eai04218  Cellular senescence
eai04261  Adrenergic signaling in cardiomyocytes
eai04370  VEGF signaling pathway
eai04380  Osteoclast differentiation
eai04550  Signaling pathways regulating pluripotency of stem cells
eai04611  Platelet activation
eai04613  Neutrophil extracellular trap formation
eai04620  Toll-like receptor signaling pathway
eai04621  NOD-like receptor signaling pathway
eai04622  RIG-I-like receptor signaling pathway
eai04625  C-type lectin receptor signaling pathway
eai04657  IL-17 signaling pathway
eai04658  Th1 and Th2 cell differentiation
eai04659  Th17 cell differentiation
eai04660  T cell receptor signaling pathway
eai04664  Fc epsilon RI signaling pathway
eai04668  TNF signaling pathway
eai04670  Leukocyte transendothelial migration
eai04714  Thermogenesis
eai04722  Neurotrophin signaling pathway
eai04723  Retrograde endocannabinoid signaling
eai04728  Dopaminergic synapse
eai04750  Inflammatory mediator regulation of TRP channels
eai04912  GnRH signaling pathway
eai04914  Progesterone-mediated oocyte maturation
eai04917  Prolactin signaling pathway
eai04926  Relaxin signaling pathway
eai04932  Non-alcoholic fatty liver disease
eai04933  AGE-RAGE signaling pathway in diabetic complications
eai04935  Growth hormone synthesis, secretion and action
eai04936  Alcoholic liver disease
eai05014  Amyotrophic lateral sclerosis
eai05020  Prion disease
eai05022  Pathways of neurodegeneration - multiple diseases
eai05132  Salmonella infection
eai05133  Pertussis
eai05135  Yersinia infection
eai05140  Leishmaniasis
eai05142  Chagas disease
eai05145  Toxoplasmosis
eai05152  Tuberculosis
eai05161  Hepatitis B
eai05163  Human cytomegalovirus infection
eai05167  Kaposi sarcoma-associated herpesvirus infection
eai05169  Epstein-Barr virus infection
eai05170  Human immunodeficiency virus 1 infection
eai05171  Coronavirus disease - COVID-19
eai05205  Proteoglycans in cancer
eai05208  Chemical carcinogenesis - reactive oxygen species
eai05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
eai05415  Diabetic cardiomyopathy
eai05417  Lipid and atherosclerosis
eai05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:eai00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    106846006 (MAPK11)
   04015 Rap1 signaling pathway
    106846006 (MAPK11)
   04370 VEGF signaling pathway
    106846006 (MAPK11)
   04668 TNF signaling pathway
    106846006 (MAPK11)
   04068 FoxO signaling pathway
    106846006 (MAPK11)
   04071 Sphingolipid signaling pathway
    106846006 (MAPK11)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    106846006 (MAPK11)
  09143 Cell growth and death
   04114 Oocyte meiosis
    106846006 (MAPK11)
   04218 Cellular senescence
    106846006 (MAPK11)
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    106846006 (MAPK11)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    106846006 (MAPK11)
   04613 Neutrophil extracellular trap formation
    106846006 (MAPK11)
   04620 Toll-like receptor signaling pathway
    106846006 (MAPK11)
   04621 NOD-like receptor signaling pathway
    106846006 (MAPK11)
   04622 RIG-I-like receptor signaling pathway
    106846006 (MAPK11)
   04625 C-type lectin receptor signaling pathway
    106846006 (MAPK11)
   04660 T cell receptor signaling pathway
    106846006 (MAPK11)
   04658 Th1 and Th2 cell differentiation
    106846006 (MAPK11)
   04659 Th17 cell differentiation
    106846006 (MAPK11)
   04657 IL-17 signaling pathway
    106846006 (MAPK11)
   04664 Fc epsilon RI signaling pathway
    106846006 (MAPK11)
   04670 Leukocyte transendothelial migration
    106846006 (MAPK11)
  09152 Endocrine system
   04912 GnRH signaling pathway
    106846006 (MAPK11)
   04914 Progesterone-mediated oocyte maturation
    106846006 (MAPK11)
   04917 Prolactin signaling pathway
    106846006 (MAPK11)
   04926 Relaxin signaling pathway
    106846006 (MAPK11)
   04935 Growth hormone synthesis, secretion and action
    106846006 (MAPK11)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    106846006 (MAPK11)
  09156 Nervous system
   04728 Dopaminergic synapse
    106846006 (MAPK11)
   04723 Retrograde endocannabinoid signaling
    106846006 (MAPK11)
   04722 Neurotrophin signaling pathway
    106846006 (MAPK11)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    106846006 (MAPK11)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    106846006 (MAPK11)
  09159 Environmental adaptation
   04714 Thermogenesis
    106846006 (MAPK11)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    106846006 (MAPK11)
   05208 Chemical carcinogenesis - reactive oxygen species
    106846006 (MAPK11)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    106846006 (MAPK11)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    106846006 (MAPK11)
   05161 Hepatitis B
    106846006 (MAPK11)
   05171 Coronavirus disease - COVID-19
    106846006 (MAPK11)
   05163 Human cytomegalovirus infection
    106846006 (MAPK11)
   05167 Kaposi sarcoma-associated herpesvirus infection
    106846006 (MAPK11)
   05169 Epstein-Barr virus infection
    106846006 (MAPK11)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    106846006 (MAPK11)
   05135 Yersinia infection
    106846006 (MAPK11)
   05133 Pertussis
    106846006 (MAPK11)
   05152 Tuberculosis
    106846006 (MAPK11)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    106846006 (MAPK11)
   05140 Leishmaniasis
    106846006 (MAPK11)
   05142 Chagas disease
    106846006 (MAPK11)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    106846006 (MAPK11)
   05020 Prion disease
    106846006 (MAPK11)
   05022 Pathways of neurodegeneration - multiple diseases
    106846006 (MAPK11)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    106846006 (MAPK11)
   05418 Fluid shear stress and atherosclerosis
    106846006 (MAPK11)
   05415 Diabetic cardiomyopathy
    106846006 (MAPK11)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    106846006 (MAPK11)
   04932 Non-alcoholic fatty liver disease
    106846006 (MAPK11)
   04933 AGE-RAGE signaling pathway in diabetic complications
    106846006 (MAPK11)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    106846006 (MAPK11)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:eai01001]
    106846006 (MAPK11)
Enzymes [BR:eai01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     106846006 (MAPK11)
Protein kinases [BR:eai01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   106846006 (MAPK11)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr ABC1 Kdo APH RIO1 Cas_CT1975 FTA2
Other DBs
NCBI-GeneID: 106846006
NCBI-ProteinID: XP_044633210
UniProt: A0A9L0JIN8
LinkDB
Position
2:455905..463235
AA seq 364 aa
MSGPRAGFYRQELNKTVWEVPQRLQGLRPVGSGAYGSVCSAYDARLRQKVAVKKLSRPFQ
SLVHARRTYRELRLLKHLKHENVIGLLDVFTPATSIDDFSEVYLVTTLMGADLNNIVKCQ
ALSDEHVQFLIYQLLRGLKYIHSAGIIHRDLKPSNVAVNEDCELRILDFGLARQADEEMT
GYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLQGKALFPGNDYIDQLKRIMEVVG
TPSPEVLAKISSEHARTYIQSLPPMPQKDLRSIFHGANPLAVDLLGRMLVLDSDQRVSAA
EALAHAYFSQYHDPDDEPEAEPYDESVEAKERTVEEWKELTYQEVLSFEPPEPPQPPSSL
ETGQ
NT seq 1095 nt   +upstreamnt  +downstreamnt
atgtcgggcccgcgcgccggcttctaccggcaggagctgaacaagacggtgtgggaggtg
ccgcagcggctgcaggggcttcgcccggtgggctccggcgcctacggctccgtctgctcg
gcctacgacgcgcggctgcgccagaaggtggcagtgaagaagttgtcgcggcccttccag
tctctggtccacgcgcggaggacttaccgcgagctgcggctgctcaaacacctgaagcac
gagaacgtcatcgggctgctggacgtcttcacgccagccacttccatcgatgacttcagc
gaagtgtacctggtcaccaccctgatgggcgccgacctgaacaacatcgtcaagtgccag
gcgctgagcgacgagcacgtccagttcctcatctaccagctgcttcgagggctgaagtac
atccactccgctgggatcatccaccgggacctgaagcccagcaatgtggcagtgaatgag
gactgcgagcttaggatcctggactttgggctagcacgccaggctgacgaggagatgacc
ggctacgtggccactcgctggtaccgcgcacctgagatcatgctcaactggatgcactac
aaccagacagtggacatctggtctgtgggctgcatcatggccgagctgctccagggaaag
gccctcttcccaggaaatgactacatcgaccagctgaagcgcatcatggaggtggtgggc
acacccagccctgaggttctggcaaagatatcctcagaacatgcccggacatacatccag
tccctgccccccatgccccagaaggacctcaggagcatcttccacggagccaaccctctg
gctgtggacctcctgggaaggatgctggtgctggacagtgaccagagggtcagtgcagcc
gaggccctggcccatgcctatttcagccagtaccacgacccggacgacgagcctgaggcc
gagccctatgacgagagcgttgaggccaaggagcgcacagtggaggagtggaaggagctc
acctaccaggaagtcctgagcttcgagcccccagagccaccgcagccacccagcagtctg
gagactgggcagtga

DBGET integrated database retrieval system