| Entry |
|
|---|
| Symbol |
ABCC4
|
|---|
| Name |
(RefSeq) ATP-binding cassette sub-family C member 4 isoform X1
|
|---|
| KO |
| K05673 | ATP-binding cassette, subfamily C (CFTR/MRP), member 4 |
|
|---|
| Organism |
|
|---|
| Pathway |
| eai04981 | Folate transport and metabolism |
|
|---|
| Brite |
KEGG Orthology (KO) [BR:eai00001]
09130 Environmental Information Processing
09131 Membrane transport
02010 ABC transporters
106846224 (ABCC4)
09132 Signal transduction
04024 cAMP signaling pathway
106846224 (ABCC4)
09150 Organismal Systems
09154 Digestive system
04976 Bile secretion
106846224 (ABCC4)
04981 Folate transport and metabolism
106846224 (ABCC4)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
106846224 (ABCC4)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
02000 Transporters [BR:eai02000]
106846224 (ABCC4)
Transporters [BR:eai02000]
ABC transporters, eukaryotic type
ABCC (CFTR/MRP) subfamily
ABCC1, 2, 3, 4, 5, 6, 10, 11, 12, 13 subgroups
106846224 (ABCC4)
|
|---|
| SSDB |
|
|---|
| Motif |
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| Position |
11:15700998..15943768
|
|---|
| AA seq |
1326 aa
MLHVYSEGKPNPLQDANLCSRVFFWWLNPLFKIGHKRRLEEDDMYTVLPEDRSKHLGEEL
QGCWDKEVLRAKTDARKPSLTKAIIKCYWRSYLVLGIVTFIEEVIKIIQPIFLGKIIDYF
EKYDPTDSAALYETYGYAFVLTACTLILAILHHLYFYHVQCAGMRLRVAMCHMIYRKALR
LSNVAMGKTTTGQIVNLLSNDVNKFDQVTIFLHFLWAGPLQAIAVTGLLWMEIGISCLAG
MAVLVILLPLQSCFGKLFSYFRSKTATFTDIRIRTMNEVITGIRIIKMYAWEKSFAELIT
SFRRKEIAKILRSSYLRGMNLASFFIASKIIVFVTFTTYVLLGNVITASRVFVAMTLYGA
VRVTVTLFFPSAIERVSEAVVSIRRIQNFLLLDEISQHDPQLPLNDGKMIVHVEDFSAFW
DKASETPTLRGLSFTVRPRELLAVVGPVGAGKSSLLSAVLGELPPSQGLVTVHGKIAYVS
QQPWVFSGTVRSNILFGKKYEKERYEKVIKACALRKDLQLLENGDLTVIGDRGTTLSGGQ
KARVNLARAVYQDADIYLLDDPLSAVDAEVSRHLFELCICQTLHEKITILVTHQLQYLKA
ASQILIVKDGEMVQKGTYTEFLKSGVDFGSLLKKENEETEQSPVPETPTLRNRTFSESSV
WSQQSSRPSLKDGTPEGQDTENAQVTLSEESRSEGNIGLKAYKNYFTAGAHWLIIIFLIL
LNIIAQVAYILQDWWLSYWANEQSALNVTVNGKENVTEKLDLNWYLGIYSGLTVATVLFG
IVRALLVFYVLVNSSQTLHNRMFESILKAPVLFFDRNPIGRILNRFSKDIGHMDDLLPLT
FLDFIQSFLQVIGVMGVAVAVIPWISLPLILLIIIFFVLRRYFLETSRDVKRLESTTRSP
VFSHLSSSLQGLWTIRAYKAEERFQELFDAHQDLHSEAWFLFLTTSRWFAVRLDAICAIF
VTVIAFGSLILAETLDAGQVGLALSYALTLMGMFQWCVRQSAEVENMMISVERVIEYTDL
EKEAPWEYQKRPPPSWPHEGVIVFDNVNFTYSLDGPLVLKHLTALIKSGEKVGIVGRTGA
GKSSLISALFRLSEPEGKIWIDKILTTEVGLHDLRKKMSIIPQEPVLFTGTMRKNLDPFN
EHTDEELWDALKEVQLKEAVEDLPGKMDTELAEAGSNFSVGQRQLVCLARAILRKNRILI
IDEATANVDLRTDELIQKKIREKFAHCTVLTIAHRLNTIIDSDKIMVLDSGRLKEYDEPY
VLLQNRDSLFYKMVQQLGKAEAAALTETAKQVYFKRNYPAITHNGHVVMNVSNGQPSALT
IFETAL |
|---|
| NT seq |
3981 nt +upstreamnt +downstreamnt
atgctgcatgtgtactcagaggggaagcccaacccgctgcaggacgcgaacctctgctcg
cgcgtgttcttctggtggctaaaccccttgtttaaaattggtcataagcggagattagaa
gaagatgatatgtatacagtgcttccagaagatcgctcaaagcaccttggagaagagttg
caagggtgctgggataaagaagttttgagagccaagacagacgcacggaagccttctcta
acaaaggcaatcataaagtgttattggagatcctatttagttttgggaattgttacgttt
attgaggaagtcatcaaaataatccagcccatatttttggggaaaattattgattatttt
gaaaagtatgatcccaccgattctgcggctttgtatgaaacgtacggctatgcattcgtg
ctgactgcctgcacactcatcttggccatcctgcaccacttatatttttatcacgttcag
tgtgctgggatgaggttgagagtagccatgtgccatatgatttatcggaaggcgcttcgc
cttagtaacgtggccatggggaagaccaccacaggccagatagtcaacctgctgtccaac
gatgtgaacaagtttgaccaggtgacaatattcttgcactttctgtgggcagggccactg
caggctatcgcagtaactggcctgctctggatggaaataggaatttcatgtcttgccggg
atggcagttctcgtcattcttctgcctttgcaaagctgcttcgggaagttgttctcgtat
ttccggagtaagaccgcaaccttcacagacatcaggatcaggaccatgaatgaagttata
actggcataagaataataaaaatgtatgcttgggaaaagtcatttgcagaacttattacc
agtttcagaaggaaggaaatcgccaagattctgagaagttcctaccttagaggaatgaat
ttggcgtcatttttcattgcaagcaaaatcatcgtttttgtgaccttcaccacctatgtg
ctcctgggcaatgtgatcacagccagccgtgtgtttgtggcaatgacactatatggggct
gtgcgtgtgaccgtcaccctcttcttcccgtcggccattgagagagtgtcggaggcagtt
gtcagcatccgaagaatccagaactttctgttacttgatgagatatcacagcatgaccct
cagctgccattaaatgatggtaaaatgatagtgcatgtggaagatttttctgctttttgg
gataaggcatcagaaactccaaccctacgaggcctttccttcactgtcagacctcgtgaa
ttgttagccgtggttggacctgtgggagcaggaaagtcatcactgttaagtgctgtgctg
ggggaactgcccccgagccaggggctggtcactgtgcatggaaaaattgcatatgtttct
cagcagccctgggtgttttcaggaactgtgaggagtaatattttatttgggaagaaatat
gaaaaggaacggtatgaaaaagtcataaaggcttgtgctttgagaaaggatttacagctt
ttggagaatggagatctaactgtgataggagatcgaggaaccacgctgagtggaggacag
aaagcccgggtcaacctcgcaagagccgtgtatcaagatgcagacatttacctcctggac
gatcctctcagtgcagtggatgcagaagttagcaggcacctgtttgaactgtgtatttgc
caaaccttgcatgagaagatcacaatcttagtgactcatcagttgcagtacctaaaagcc
gccagtcagattctgatagtgaaagatggtgaaatggtgcaaaaggggacctacactgag
tttctgaaatctggggtagattttggttcccttttaaagaaggaaaatgaggagactgaa
caatctccagttccagaaactcccacactgaggaatcggaccttctcggagtcttcggtt
tggtctcaacagtcttctagaccgtcactgaaagatggcactccagagggccaagatact
gagaacgcacaggttacgctatcagaggagagccgttctgaaggaaatattggtcttaag
gcctacaagaattacttcacagctggtgctcactggcttatcatcattttccttattcta
ttaaacatcatagcacaggtggcctacattcttcaggactggtggctttcatactgggca
aatgagcagagcgccctgaatgtcactgtaaatggaaaagaaaatgtaactgagaagctc
gatcttaactggtacttaggaatttattcaggtttaactgtagctaccgtcctttttggc
atagtgagagctctgttggtattctacgtccttgttaattcttcacaaactttgcacaac
agaatgtttgagtccattttgaaagctccggtattgttctttgatagaaatccaatagga
agaattttaaatcgtttctccaaagacattgggcatatggatgacttgctgcccctgaca
tttctagatttcatccagtcatttctacaagtgatcggtgtgatgggtgtggcggtggcg
gtgattccttggatttcgttacccctgattctcctcatcatcattttctttgttcttcgg
cgatatttcttggaaacatcaagagatgtcaaacgcctggaatctacaactcggagcccg
gtgttttcccacttatcgtcttctctccaagggctctggaccatccgggcatacaaagct
gaagagaggtttcaggaactgttcgacgcacaccaggatttgcattcagaggcttggttc
ttgtttttgactacgtcccgatggtttgctgtgcgtctggatgccatctgtgccatcttt
gtcactgttattgcctttggatcgctgattctggcagaaacattggacgctgggcaggtt
ggtctggcattgtcctacgccctcacgctcatggggatgttccagtggtgcgtcaggcag
agcgctgaagttgagaatatgatgatctcagtggaacgggtgattgaatatacagacctc
gagaaagaagcgccttgggaataccagaaacgccccccgcccagctggccccacgaagga
gtgattgtctttgataatgttaacttcacatacagtttagacgggcctctggtgctgaag
cacctgacagcgctcattaaatcaggagaaaaggttggcattgtgggacgaacaggagct
ggaaaaagttccctcatctcggccctttttagattgtcagaacccgaaggtaaaatttgg
attgataagatcttgacaaccgaagttggacttcacgatttaaggaagaaaatgtcaatc
atacctcaggaacctgttttattcactggaacaatgaggaaaaatctggatccctttaat
gaacatacagatgaggaactatgggatgccttaaaagaggtacaacttaaagaagccgtg
gaagatcttcctggtaaaatggatactgaattagcagaagcaggatcgaactttagtgtg
ggacagagacagttggtgtgccttgccagggctattctcaggaaaaatcggatattgata
attgacgaagcgacagcaaatgtagatctaagaactgatgagttaatacaaaaaaaaatc
cgtgagaaatttgctcattgcactgtgctaaccatcgcgcacaggttgaacacgattatt
gacagcgacaagattatggttttggattcaggaaggctgaaagaatatgatgagccgtat
gttttgctgcaaaatagagatagcctattttacaagatggtgcaacaactgggcaaggca
gaagctgctgccctcactgaaacagcaaaacaggtgtacttcaaaaggaattatcctgct
attactcacaatggccatgtggttatgaacgtgtccaatggacagccctcagccttaact
atttttgagacagcactgtga |
|---|
