Escherichia albertii: EAKF1_ch1347
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Entry
EAKF1_ch1347 CDS
T03986
Symbol
leuA
Name
(GenBank) 2-isopropylmalate synthase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
eal
Escherichia albertii
Pathway
eal00290
Valine, leucine and isoleucine biosynthesis
eal00620
Pyruvate metabolism
eal01100
Metabolic pathways
eal01110
Biosynthesis of secondary metabolites
eal01210
2-Oxocarboxylic acid metabolism
eal01230
Biosynthesis of amino acids
Module
eal_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
eal00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
EAKF1_ch1347 (leuA)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
EAKF1_ch1347 (leuA)
Enzymes [BR:
eal01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
EAKF1_ch1347 (leuA)
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Motif
Pfam:
HMGL-like
LeuA_dimer
HCS_D2
IPMS_D2
Motif
Other DBs
NCBI-ProteinID:
AHE59243
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Position
1426662..1428233
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AA seq
523 aa
AA seq
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MSQQVIIFDTTLRDGEQALQASLSVKEKLQIALALERMGVDVMEVGFPVSSPGDFESVQT
IARQVKNSRVCALARCVEKDIDVAAESLKVAEAFRIHTFIATSPMHIATKLRSTLDEVIE
RAVYMVKRARNYTDDVEFSCEDAGRTPIADLARVVEAAINAGATTINIPDTVGYTMPFEF
AGIIRGLYERVPNIDNAIISVHTHDDLGLAVGNSLAAVHAGARQVEGAMNGIGERAGNCS
LEEVIMAIKVRKDILNVHTAINHQEIWRTSQLVSQICNMPIPANKAIVGSGAFAHSSGIH
QDGVLKNRENYEIMTPESIGLNQIQLNLTSRSGRAAVKHRMDEMGYKESEYNLDNLYDAF
LKLADKKGQVFDYDLEALAFIGKQQEEPEHFRLDYFSVQSGSNDIATAAVKLVCGEEVKA
EAANGNGPVDAVYQAINRITDYNVELVKYSLTAKGHGKDALGQVDIVANYNGRRFHGVGL
ATDIVESSAKAMVHVLNNIWRAAEVEKELQRKAQHNENNKETV
NT seq
1572 nt
NT seq
+upstream
nt +downstream
nt
atgagccagcaagtcattattttcgataccacattgcgcgacggtgaacaggcgttacag
gcaagcttgagtgtgaaagaaaaactgcaaattgcgcttgcccttgagcgtatgggtgtt
gacgtgatggaagtcggtttccccgtctcttcgccgggcgatttcgaatcggtgcaaacc
atcgcccgccaggtcaaaaatagccgcgtatgcgcgttagcccgctgcgtggaaaaagat
atcgacgtcgcggctgaatctctgaaagtcgccgaagccttccgtattcatacctttatt
gctacctccccaatgcacatcgctaccaagctgcgcagcacgctggatgaagtgatcgaa
cgcgctgtttatatggtgaaacgcgcacgtaattacaccgatgacgttgaattctcttgc
gaagatgccgggcgtacaccgattgccgatctggcacgggtagtagaggcggcgattaac
gccggagccaccaccatcaacatcccggacactgtaggctacaccatgccgtttgagttc
gccggaatcatccgcggtctgtatgaacgcgtgcccaacattgataacgccattatttcc
gttcatacccacgacgatttaggtctggcagtaggcaactcgctggcggcggtacacgcc
ggagcgcggcaggtggaaggagcaatgaacgggatcggcgaacgcgccggaaactgttcg
ctggaagaagtgatcatggcgatcaaagttcgcaaggatatccttaatgtacataccgcc
attaatcaccaggagatatggcgcaccagtcaattagttagccagatttgtaatatgccg
atcccggcaaacaaagccattgttggcagcggcgccttcgcacactcctccggtattcac
caggatggcgtactgaaaaaccgcgaaaactacgaaatcatgacgccagaatctattggt
ctgaaccaaatccagctgaatctgacctcccgttcgggccgtgcggcagtaaaacatcgc
atggatgagatgggatataaagaaagtgaatacaatctggacaatctgtacgacgctttc
ctgaagctggcggataaaaaaggtcaggtgttcgattacgacctggaggcgctggccttc
atcggtaagcagcaagaagaaccggaacattttcgtctggactatttcagcgtgcagtct
ggttctaatgatatcgccactgccgccgtcaaactggtatgcggcgaagaagttaaagca
gaagccgccaacggtaacggcccggtggatgccgtctatcaagccattaaccgcatcacc
gactataacgtcgagctggtgaaatacagcctgaccgccaagggtcacggcaaagatgcg
ctgggccaggtggatatcgtcgccaactacaacggtcgccgcttccacggcgtcggccta
gccaccgatattgtcgagtcctccgccaaagccatggtgcacgtactgaacaatatctgg
cgtgccgcagaagtcgaaaaagagttgcaacgcaaagctcaacacaacgaaaacaacaag
gaaaccgtgtga
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