KEGG T06747: GXP68

Ewingella americana: GXP68_00640

Entry

GXP68_00640       CDS       T06747

Symbol

folC

Name

(GenBank) bifunctional tetrahydrofolate synthase/dihydrofolate synthase

K11754

dihydrofolate synthase / folylpolyglutamate synthase [EC:6.3.2.12 6.3.2.17]

Organism

eame Ewingella americana

Pathway

eame00790

Folate biosynthesis

eame01100

Metabolic pathways

eame01240

Biosynthesis of cofactors

Module

eame_M00126

Tetrahydrofolate biosynthesis, GTP => THF

Brite

KEGG Orthology (KO) [BR:eame00001]
09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    GXP68_00640 (folC)
Enzymes [BR:eame01000]
6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.2  Acid-D-amino-acid ligases (peptide synthases)
    6.3.2.12  dihydrofolate synthase
     GXP68_00640 (folC)
    6.3.2.17  tetrahydrofolate synthase
     GXP68_00640 (folC)

SSDB

Motif

Pfam:

Mur_ligase_C Mur_ligase_M SBDS_C

Other DBs

NCBI-ProteinID:

QMV50021

LinkDB

Position

139833..141098

AA seq 421 aa
MSEKVGVPQATSDLHDWLSYIDSLHSQVIDMSLNRIKAVANTLDVLKPAPFIFLVGGTNG
KGTTCHTLEKTLQLSGYKVGVFSSPHMINYTETVRIQGKELAGSEHVAAFVAINHARQDT
TLTPFEFNTLGAFWLMKQAQVDVAIIEVGMGGRDDATNIIEPDISVITNVALDHEDWLGK
DTEAIGEIKAGIFRAGKPAIIGQASAPASLLSYAQKIGAVTYQRDANWQLDVQENQWSFS
DAAGQLTDLAIPKMPLENVATAIAALRASGLKFTPAALQEVILHANLPGRFQIIGNNPTT
ILDVAHNPHAAAYLAERLRKFPIKGNYRFVIGMLINKDIKGTVDHLKTLSDKWYCCGVQA
GPRSTKPEDVAQYLPQAQKFADILAGWEAAKRDVEEGDVIVVCGSFFTVAPVLNALNSAS
E

NT seq 1266 nt +upstreamnt +downstreamnt
atgagtgaaaaagtcggtgttccacaggcaacttccgatttgcatgactggctgtcttat
attgatagtctccactcgcaagttatagatatgagtcttaatagaattaaagcggtggct
aatactttagatgtattaaaacctgcgccatttatctttctggtgggtggcaccaatggt
aaaggtaccacctgccatacgctggaaaaaacgctgcaactttctggctataaagtcggg
gtgtttagttcgcctcacatgattaattacactgaaaccgtgcgtattcagggtaaagag
ctagccggtagcgagcacgtcgccgcctttgttgccatcaaccatgcccgtcaagacact
acactgaccccctttgaattcaatacattgggtgctttctggctgatgaagcaggcgcag
gtggatgtggcgattatcgaagtcggcatgggcgggcgcgatgatgccaccaatatcatc
gagccggatatttcggtgataactaacgttgcgctggaccacgaagactggttgggcaaa
gacaccgaggctattggcgagatcaaagccggtattttccgcgccggtaaacctgccatc
attgggcaggcgagcgcgcccgcttcgctgctgtcctatgctcagaaaattggcgcggtg
acttatcagcgtgacgccaattggcaactggatgtgcaggaaaaccagtggtcattcagc
gatgccgcaggccaactgactgacttagccattcctaaaatgccgctggaaaacgtggcg
accgcgattgccgctctgcgcgccagcggattaaagttcacccctgctgcgttgcaagag
gttattcttcacgccaatttgccgggccgcttccaaattattggtaataacccgaccact
attttagatgtcgcgcataacccgcacgcggcggcttatttagcggaaagattacgcaaa
ttcccaattaagggaaattatcgttttgttatcgggatgcttattaataaagatatcaaa
ggtactgtcgaccatttaaaaactttatctgataaatggtattgctgtggagtgcaggcc
gggccgagaagcactaagccggaagatgtcgcgcaatatttaccgcaggcgcaaaaattc
gccgatattttggcgggctgggaagctgctaaacgtgatgttgaagaaggcgatgtgatt
gtggtttgcgggtcattcttcaccgtcgcgcctgtgttgaacgcattgaactcagcgtct
gaataa

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