Ewingella americana: GXP68_06545
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Entry
GXP68_06545 CDS
T06747
Symbol
folC
Name
(GenBank) bifunctional tetrahydrofolate synthase/dihydrofolate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
eame
Ewingella americana
Pathway
eame00790
Folate biosynthesis
eame01100
Metabolic pathways
eame01240
Biosynthesis of cofactors
Module
eame_M00126
Tetrahydrofolate biosynthesis, GTP => THF
Brite
KEGG Orthology (KO) [BR:
eame00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
GXP68_06545 (folC)
Enzymes [BR:
eame01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
GXP68_06545 (folC)
6.3.2.17 tetrahydrofolate synthase
GXP68_06545 (folC)
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GFIT
Motif
Pfam:
Mur_ligase_C
Mur_ligase_M
Motif
Other DBs
NCBI-ProteinID:
QMV51044
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Position
1395525..1396796
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AA seq
423 aa
AA seq
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MQNQPIPQATSPLAAWLYYLENLHSQAIELGLKRVKAVAAKLDLLQPAPFVITVAGTNGK
GTTCRTLEAIMMAAGLRVGVYSSPHLVRYTERVRIQGEELPEQAHCQSFATLEAGRGDIP
LTYFEYGTVSALQLFKHAKLDVVILEVGLGGRLDATNIVDANVAVVTSIALDHTDWLGSD
RESIGREKAGVFRGQTPAVVGEPDMPQSIADVAAEKGSELYRVGENWRYAEEGDSWSWQA
VEGKSLADLPIPNVPLANAATALAALHFSKLEIAEEAIRRGLQQAQLPGRFQTVSELPRL
ILDVAHNPHAAAYLAGRLSELPRNGGKVRAVVGMLHDKDIAGTLACLSPQVDFWYCAPLE
GPRGASVEELSVHLTQAYQFTDVVCAWQQAMQDADSQDIVIVCGSFHTVAHVMAALDAGK
TSG
NT seq
1272 nt
NT seq
+upstream
nt +downstream
nt
atgcagaatcaacctattccccaagccacgtcgcctttggccgcgtggctttattatctc
gaaaatctccattctcaagcgatagagctgggtctcaagcgtgtcaaagcggtcgccgct
aagctcgacttgctgcaacccgcaccttttgtcatcactgtcgccggaaccaatggcaag
ggcaccacctgccgcacgctggaagctatcatgatggctgcgggtttgcgcgtcggcgtc
tacagttcacctcatttggttcgctacaccgagcgggtcagaattcagggtgaagagctg
ccagaacaagcacattgccaatcttttgctacgcttgaagccgggcgaggtgatattcct
ctgacctatttcgagtacggcaccgtctccgctttgcagctgtttaagcacgccaaactg
gacgtggttatcctcgaagtgggccttggcgggcgccttgatgccaccaatatcgtcgat
gccaacgtggccgtggtgaccagtatcgcgctggatcacactgactggttagggtcagac
cgcgaaagtattggccgcgaaaaagctggcgtgttccgtggtcaaacgcccgccgtggtt
ggcgagcctgatatgccgcagtcgattgctgacgtggccgcagagaagggttccgagctg
tatcgcgtgggtgaaaattggcgctacgccgaggaaggcgacagctggagctggcaggcc
gtcgagggcaagtcgctggcggatttgccaattcctaatgtcccgctcgccaatgccgcg
acggcgctggcggctttgcatttcagtaagttagagattgccgaagaggcgattcgccgt
ggcttgcagcaggcacagctgccgggtcgtttccagacggtaagcgagttgccgcgtctg
attctggatgttgcgcataacccgcacgccgcggcatatctggctggacgtttgtccgaa
ttgccacgcaacggcgggaaagtgcgcgcggtagtcggtatgctgcatgataaagatatt
gcgggtactctggcttgcctttcgccacaagtggatttttggtactgcgcgccgctcgaa
gggccgcgcggtgccagtgtagaagaactctctgtgcatctgacgcaagcgtatcagttc
acggatgtggtttgcgcctggcagcaggcgatgcaggatgctgatagtcaggatattgtg
attgtctgcggatcatttcataccgtagcgcacgtgatggctgctttagacgcggggaaa
accagtggctag
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