Ewingella americana: GXP68_17460
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Entry
GXP68_17460 CDS
T06747
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
eame
Ewingella americana
Pathway
eame00300
Lysine biosynthesis
eame00550
Peptidoglycan biosynthesis
eame01100
Metabolic pathways
eame01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
eame00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
GXP68_17460 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
GXP68_17460 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
GXP68_17460 (murF)
Enzymes [BR:
eame01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
GXP68_17460 (murF)
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
P-II
Motif
Other DBs
NCBI-ProteinID:
QMV52928
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Position
complement(3812257..3813618)
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AA seq
453 aa
AA seq
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MIRVSLQALANELNAELIGADAQIDAVVTDTRKIESGCLFVALKGEKFDAHDFAADAIAA
GAGALLVSKRLPVEVPQLVVADTRIALGRLGAWVRQQVPARVVGLTGSSGKTSVKEMTAA
ILRQCGNVLYTAGNLNNDIGVPLTLLRLTAEHNFAVIEMGANHGGEIAYTTDLVRPETAL
VNNLAAAHLEGFGSLAGVAQAKGEIFEGLPANGVAILNADSNDWPHWQRHLHNKTVWRFS
PEAGEDIDFFASDVQISPLKTAFTLHAPQGVVEVSLPLPGRHNIANALAAAALALSVGAT
LDNVRQGLSTLQAVPGRLFPIALSEGKTLLDDSYNANVGSMTAAAQTLAEMPGYRVMAVG
DMGELGAESENCHREVGEAIREAGIDKVFSVGTASKTISDVSGCGEHLQDKSALTARLTS
LLSEHAVITVLIKGSRSAAMEQVVRALQENATC
NT seq
1362 nt
NT seq
+upstream
nt +downstream
nt
atgatccgcgtttcccttcaggcactggctaacgaactcaatgctgagttgatcggcgcg
gacgcgcagattgacgccgtggtgaccgatacccgcaaaattgagtcgggttgcctgttc
gtcgcgctcaaaggcgaaaaatttgatgctcacgactttgctgctgatgccattgccgca
ggagcgggggcattgttggtaagtaagcgcttaccggtggaggttccgcaactggtggtt
gccgacactcgcatcgccctcgggcgccttggcgcttgggttcgccagcaggttcctgcc
cgcgtggttggcctgaccggctcctctggcaagacctcggtgaaagagatgaccgcggcg
attttgcgccagtgcggcaacgtgctttataccgcaggcaacttaaataacgacatcggc
gtgccattaaccctgctgcgcctgacggcggaacacaatttcgccgtgatcgagatgggc
gcaaaccacggtggtgaaattgcttataccaccgatttagtgcgtcctgagacggctctg
gtcaacaaccttgccgctgctcacctcgaaggtttcggctcactggcgggcgttgctcag
gccaagggtgaaatcttcgaaggcttgccagccaatggcgtcgccattcttaatgccgac
agcaacgactggccgcactggcagcgccatctgcataacaaaaccgtctggcgcttctca
ccagaagcgggcgaagacattgatttctttgcctcagacgtgcagataagcccgctgaag
accgcctttactctgcatgcgccacagggcgtggtggaagtttctctgccgctaccgggg
cgtcacaacattgctaatgctctggccgctgcggccttggcgctctccgttggcgcgacg
ttagacaatgtccgccaagggctgtccactttacaggccgtgccggggcgtctgttccct
atcgccctgagcgaaggcaaaacgctgctcgatgacagctacaacgccaacgtgggctcg
atgactgccgccgcgcagacgctggctgaaatgccgggttatcgcgtgatggcggtgggc
gacatgggcgaactgggtgcagaaagtgagaattgccatcgcgaagtgggtgaagccatc
cgcgaagcaggcatcgataaagttttcagcgtgggtaccgccagtaaaaccatcagcgac
gtgagtggctgtggcgaacatctgcaagataagtcagccctgacggcccgtttaacgagc
ttactgtcagaacacgcggtcatcaccgtcttaattaagggttcacgtagtgccgccatg
gagcaggtagtacgggcgttacaggagaatgcaacatgctag
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