Klebsiella aerogenes EA1509E: CCG29230
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Entry
CCG29230 CDS
T02447
Name
(GenBank) Putative peptide/polyketide synthase
KO
K26573
colibactin biosynthesis hybrid nonribosomal peptide/polyketide synthase
Organism
ear
Klebsiella aerogenes EA1509E
Pathway
ear01054
Nonribosomal peptide structures
Brite
KEGG Orthology (KO) [BR:
ear00001
]
09100 Metabolism
09109 Metabolism of terpenoids and polyketides
01054 Nonribosomal peptide structures
CCG29230
09180 Brite Hierarchies
09181 Protein families: metabolism
01008 Polyketide biosynthesis proteins [BR:
ear01008
]
CCG29230
Polyketide biosynthesis proteins [BR:
ear01008
]
Polyketide synthase (PKS)
PKS-NRPS hybrid
Bacterial type (modular)
Colibactin synthetase
CCG29230
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
AMP-binding
ketoacyl-synt
Acyl_transf_1
Ketoacyl-synt_C
Condensation
PP-binding
KR
ADH_zinc_N_2
ADH_zinc_N
PKS_DH_N
CurL-like_PKS_C
adh_short
adh_short_C2
KAsynt_C_assoc
RhiE-like_linker
ADH_N
PS-DH
SpnB_Rossmann
AMP-binding_C
NAD_binding_10
Epimerase
Thiolase_N
Motif
Other DBs
NCBI-ProteinID:
CCG29230
LinkDB
All DBs
Position
434242..443073
Genome browser
AA seq
2943 aa
AA seq
DB search
MSPDVCQKIQTLCSDYRITPAVIFYVAWGILLQRWCYADDVLFGATISGRNIPIDGIEET
LGLFINTLPLRLRDDGATLLQHLQRMHQTLIAHYSNEHDALASIQRLVHKEGHAGDLFNT
LVVLENYPVDMTLLSCASPVAIRHLSVHEQTHYPLTLTITQQKGFRFSIAYALNYLTNNM
AQALLMHLSYLLEQLVDNPQRPIAALVNLSPCQQAQVLQPYLERMACRDWDSQSNVIEQF
HQVAATSPAQVAVVDELCALTYSELAAQAEQLAAYLVQQGVMVGDTVGIISERRVNTVVA
IIAIMLIGAAYVPISPDYPVGRMQEIIDDSGLALLLVHGKPLDALNVAQSDLCAFPVAPS
VVFPVITPDSRAYVIYSSGSTGKPKGIAVAHRGLLRLIQGDSPLKVESGETTLLTCPFEF
DVSVFEMWSTLLNHGKLVLLSKQALLDINHIRRTIADEQVARAWFTSSLFNSYVAEGADF
FGMLQHITVGGEAVSAWHVNDVMQKYPHLVVTNGYGPTENTIFTTAYRFNGLQPARVPIG
YAVPGTSLYITDLHGHLLPIGATGELVAGGVGVAIGYQNNPALSATVFVPDPFIPGGMMY
KTGDYARLLDDGCVDCFGRKDGQIKINGQRIETGEIEQRLLECSGIIEAVVVPYRVRETL
HIAAVVCVNDSYDEVEVRGQLADRLPPFAIPESLVVVTEIAKSHSGKADLAQLRYLLPAT
QCNAVSTTISEVHSDMEHALHAIWQRVLDRQDIDSNASFFALGGTSLDTIRVKGDIKRQL
GLEIDITDLFKYPTLTALAHFLDTAVSPEDAIPTRAVVYSDMPVAIVGMAGRFPGAANIA
ALWTLVVGGESGLTLFSDEELRAHGVTPDTLKQANYIKTKGIVDDHEWFDADFFGYTPNE
AECMDPQIRLLHQCCWQTLEHAGCDPATFTGAIGIYAGLLTSPHWLNAVMQDTTDSTALY
KASILNIHSVTALIAHALNLTGPAVTLDTACSTSAVAIHQACIALRNRDCDAALAGGVSI
EMPAYRGYEYHEGMINARDGVCRPFDSQASGTVTGDGLGMLLLKRLDDALADRDCIYGVI
KGSAVNNDGNNKIGYTAPSVIGQSTVIRTSLRRAGFDSDSIGLVEAHGTGTVLGDPIELR
ALNEVFGPTPVPFCVVSALKSNIGHLNSAAGVAGVIKTTLALHHQVLPPTAHFRQLNPAI
DLSRSALYVNQQVQPWPSTRPRRALVSSFGIGGTNASIALEAHQHEDDPSATGVRDSYLL
LFSAKTPAALELRVASTLEYVKHGVGVRLPDVAYTLQTGRTAFDHRRAYLVSRGSKIDLS
CATILQAEIFNGQRTTAEICFMFPGQGSQYHGMASALYAHQPMFRQHMDRCFAAFQRYST
VDLKALLFDDEDTRDIDQTQFTQPALFCVEYSLARTLIDLGITPDSMIGHSLGEYVAACI
AGVFTLEDALHVIEARGRLMQSMRPGSMMAVYLSREQLTPWLAAERGIELAANNSAHFCV
VAGEQAAISRLSTRLVEGGIQHRRLKTSHAFHSAMMTPMLHDFAQLLGQIPMHAPHKRFI
SNVSGTWITEEQATSPDYWVQQVRNAVLFSEGAAQLLVQPTLFIECGPGNTLSTFIQGHN
QYSDQPTLLTLRKANAAIDDEHMLHRTLAALWVRGENIDWRRFNQTALGKHIPLPDYPFE
QTYYYRYGAALSGYRQYPNPLRRPQDEWLQRVLWRMHDTSLREAFYAPGELIIIISADGD
KLQQTLMSSGVDSITMPLPISSEDDVWDNDRILTHFHDICALLAHKTYRQLHCLYAPGAE
AGSSLTQSLSGLYRVARWCMHSTTPLASLTVLTHGAFRVQEEDNPEPTLAALSGAVNVFA
QELHPTEVRLIDIDAQSSDENLNLLTQRLAPKQETVMALRQGMLYLRRFIPTRLLAHLPP
QTGCIPGNVLWIIGGEKGIGRMIGEALAQREGVRVVLSSRTGYHHEAVQQDALDVIHCDV
TQAEAVRACLATLLERYGRLDGVIFAADATTTLTLHQLSESALRDTLTVKERGTANVLHA
LAQRNLLDERLLLLFCNSLAAVNAEIGQTGYATASAYLDALAQQLRTRYKVNALSIGLDA
LREQGMLLDAINGSEYDVLRGLRPLMTGTLLQAYKQQGADTSYYARLSPESDWLLDEHRI
SGIATLPGTGYLALAYEALRHYFVQDQICIDELVFLAPLTVMDNCSVDVFVDISPNGQGV
SVEVKSMTERFSGTLTTHARGRATRLMVDDNVVCDLTGLMREMHTITPPTKELSSTHFHY
GPRWHSVQQLYGNTAQTQVFATLALPTVAANDTIALHPALLDIASSVVEQLPGFHTDSVP
FLYQDLRLYRPLPNTLHVALTVNRHDEEGDSYAFTLYDMAGEMVARCAAMVKRKVQLHIQ
DVDDDTRLRVPSADNYQLRLAAEGEGAGKLALCPTPRLALGDSQVEIEVLATGLNFKDVL
FTTGLLRQQPGEAPLQLGLECAGRITRVGKNVTEFAPGEDVMAVLNGGFVQYARVESDCV
VRKPAHCRIEQAAALPIAYLTAYYALVVRANLQPGERVLIHSAAGGVGLAALHIAKRCGA
QIFATAGSEQKRDYLLSLGVHAVADSHDEQFAATLLTASDGQGMDVILNSLTGRLLDASL
ALLAPLGRFLELGSKDIVEDKALPMRFFAQGGTFIPINFHAAHGAFSRYLQQIVAWIDDN
TLPLLPCKSVPLPEVARAFATLTTPQHIGKVVVTHRTAAGMDRLNAMIAERRLGGYALSM
SNAEVMRQLWPILNTRSPWAQLLLSPRAIDRLARGNRVDRGVPSAANDTITQQTVKKRPR
PEIGVPYSPATREVERVLCQILEEYLGLDRVGIDDNYAELGATSLDMVQLSGQMARHYPQ
VSVVSLYNHATVRQLATFCQPPEGESNAPSPQPAVQTNTRANQIAKRALQIAKNTARSHT
SLH
NT seq
8832 nt
NT seq
+upstream
nt +downstream
nt
ttgtctccggatgtgtgtcagaaaatacagacgctatgcagcgattatcgtatcaccccc
gcagtaatcttctatgtggcctggggcatcctgctacaacgttggtgctatgctgacgat
gtgttattcggcgcgacaatatcagggcgaaatataccaattgatggtatagaagaaaca
ctagggctatttattaacacgttgccgctgcgtctgcgtgatgatggggcgacactgttg
caacacttacaacgtatgcaccaaacactaatagctcactacagcaatgaacatgatgcc
ttagccagcatacaacggttggtacataaagaaggtcatgctggggatctttttaatacc
ttagtggtgttggagaattatcccgttgatatgacattattgtcatgcgcgtcgcccgtg
gcaattcgccatctcagtgtacatgaacaaacgcactatccgctgaccttgaccatcact
caacagaagggattccgtttcagtattgcatatgcccttaactacctgaccaacaacatg
gcgcaagcgttgctgatgcacctgagttatctgcttgaacaactggtggacaatccgcag
cgccccattgctgcgttggtaaacttgtccccatgccagcaggcgcaggtacttcaaccc
tatctggaacgcatggcatgccgggattgggatagtcaatccaacgtcatcgaacaattt
catcaagttgctgcgacttcgccagcacaggtcgcagtggttgatgaattgtgcgcgttg
acctattcggagttggcagcacaagctgagcagctcgcggcttatttggtacagcagggt
gttatggttggcgatactgtaggcataattagcgaacgccgggtaaacaccgtggttgcc
atcatcgccatcatgttgatcggggctgcttatgtgcccatcagccccgactacccagtg
ggtaggatgcaggaaattattgatgacagcggcttggcgctgttgctggtacatggcaaa
ccgctagatgcattaaacgttgcgcagagtgacctctgtgcatttcccgtcgcgccctcg
gtggtatttccggttatcacaccagattctcgcgcttatgtgatttattcatcggggtcg
acgggtaagccaaaaggtatcgcggtggcgcaccgcggtttattgcgcctgatacaaggc
gacagcccgctgaaggtggagagcggtgagacaacgctgctgacctgcccatttgagttt
gatgtttcggtgtttgagatgtggtctaccttgctcaaccacggcaaactagtattactc
agcaaacaggcattacttgatatcaatcacattcgccgcacgatcgctgatgaacaggtg
gcgcgcgcctggtttacctcatccttgtttaactcctatgtggcagaaggtgccgatttc
ttcggtatgttacaacacattacggtgggcggcgaagcagtatctgcgtggcatgtcaac
gacgtgatgcaaaaatacccgcatctggtggtgacaaacggttatgggccgacggaaaac
actatttttaccaccgcatatcgtttcaacgggttgcaacccgcccgagtcccgatagga
tacgcggtaccgggcacctcgctctacattaccgatctccatgggcatttgttgcctatc
ggtgccaccggtgaactagtggcgggtggagtgggggtcgccatcggctatcagaacaac
ccggcgctaagtgcgacggtttttgtccctgatccttttattcccggcggtatgatgtac
aaaactggcgattatgcccggttgctggatgatggctgtgttgactgttttgggcgtaaa
gacggtcaaattaagatcaatggacaacgaattgaaaccggagagatcgagcagcgcctg
ctggagtgctccggcattatcgaggcggtagtggttccttaccgcgtacgtgaaacgctg
catattgcggcagtggtctgcgtcaatgatagctatgatgaggtggaagttcgagggcaa
ttggctgacagattgccgccattcgctattccggaatccttggtggtggtgacggagatt
gcaaaaagccatagtggcaaggccgacttggcgcagttgcggtatctcctgcccgcaact
cagtgcaacgccgtgtccaccacgatatcagaggtgcatagtgacatggaacatgcgctg
catgctatctggcaacgcgtacttgatagacaagacattgatagcaatgcctcctttttc
gccctcggtggcacctcattggataccatcagggttaaaggggatattaagcggcaactt
ggcttggagattgatattaccgatctctttaagtacccaacgctcacggcgttagcacat
tttctcgatactgccgtatcgccggaggatgcaattccaacgcgtgctgttgtctacagc
gacatgccggtggcgattgtcggtatggcgggacgtttccccggtgcggcgaatattgca
gcgttgtggacgctggttgtaggaggggaatcgggattaacactgttcagtgatgaagag
ttgcgcgcgcatggtgtgacacctgacacgcttaaacaagcgaattatataaaaaccaaa
gggattgttgatgatcacgaatggtttgatgcggatttctttggttatactcccaacgag
gcggaatgtatggatccgcaaattcgcttattgcatcagtgctgctggcaaactctggaa
cacgctgggtgcgatcctgccacctttactggtgcgattggcatttatgccggactgctg
acatccccccactggcttaatgcggtaatgcaagacactaccgactctaccgccctgtac
aaggccagtatcctgaatatccattccgtcacagcattgattgcccatgcgcttaacctc
accggccctgccgtgacgcttgacaccgcctgctccacttcggcagtggctatccaccag
gcctgcatcgcactacgtaaccgggattgcgatgcggcattggcgggcggcgtttctatc
gagatgcctgcgtaccggggctatgaatatcatgaaggcatgatcaatgcgcgagatggt
gtctgtcgtcctttcgatagccaagcctctggcacagtcaccggtgatggcttaggaatg
ctgctgctaaaacgtctggacgacgcgctggcggatcgggactgcatctatggtgtgatc
aaaggttcggcggtcaataatgatggcaataacaaaatcggctataccgcgccgagtgtg
atcgggcaatcaacggtaatccgcaccagtttgcgccgtgccggttttgatagcgacagt
atcggattggtggaagcgcacggcaccggtacggtgctgggtgatcctattgagttacgt
gcgcttaatgaggtgtttggcccaacacctgttccgttttgtgtggtttcagcgctgaaa
agtaatattggccacctcaactccgctgcgggagtggcgggcgtcatcaaaacaacgctc
gccctgcatcatcaagtgttgccaccaacagcgcactttcgccaactcaatcctgctata
gatctatcgcgttctgcattgtacgttaaccagcaagtccaaccgtggccgtcgacgcgt
cctcgtcgtgcactggtgagctccttcggcatcggcggcaccaatgccagcatcgcacta
gaagcacatcaacatgaggacgacccttcagcgacgggggtacgcgacagctatctgttg
ttgttctccgctaaaacacccgctgcgttagagttgcgcgtggcctccacactggaatat
gtcaagcatggagtaggggtgcgcctgccggatgtggcttatacattgcaaactggacgc
acagcctttgaccatcggcgggcttatttggtgagtcgtgggtcgaaaatcgatctctcc
tgtgccacgatattgcaagcggaaatcttcaatggtcagcgcacgacagcggagatctgc
ttcatgtttcctggtcaaggtagccaatatcacggcatggccagcgcgctctatgctcat
caacccatgtttcgccagcacatggatcgctgctttgctgcattccaacgctattcgacg
gtcgatctcaaggcgttgttgtttgacgatgaggatacgcgggatattgatcaaacgcag
ttcacacaaccggcgttgttctgtgtcgaatacagcctagcgcgcaccttgattgatctg
gggattacgccggacagtatgatcgggcacagtctgggcgagtatgttgcggcctgtatt
gctggcgtatttactcttgaggatgcgctgcacgtcattgaggcgcgcggacgtttgatg
cagtccatgcgtcccggtagcatgatggcggtctaccttagtcgcgaacagttgacccca
tggctagctgcagaacggggtattgaactggcagctaataatagcgcgcatttttgcgta
gtcgcgggagagcaggcggccatttcccgtttgagcacacgcttagtcgagggcgggata
cagcacaggcgcctgaaaacctctcacgcattccactcggccatgatgacgccgatgctg
cacgattttgcacagttgctggggcaaatcccgatgcacgcgccgcacaagcgctttata
tctaatgtaagcggtacatggattactgaggagcaagctacctcgccggattactgggtg
cagcaagtgcgcaacgcggtgctgtttagcgaaggtgcggcgcaactgttggtacaaccc
acgctgtttatcgaatgtgggccgggtaatacgctctctacctttattcaaggacataac
caatacagcgatcagccgaccctgttgacgctacgcaaagccaacgcggcgatcgatgat
gagcacatgttgcatcgtacgctggcggcgctgtgggtcaggggggagaatattgattgg
agacgctttaaccagacggcactcggcaagcacattccattgccggattaccccttcgaa
cagacttattactatcgctatggtgctgcactttccggttatcgccagtatccaaatcct
ctgcgccgtccgcaagatgagtggctccagcgtgtgctgtggcggatgcacgacacatcc
ttgcgggaggcgttctatgcgccgggcgaattgatcatcattattagtgctgacggcgac
aagttacagcagacgctgatgagtagtggtgtcgacagcatcacaatgccgctgccgata
tcgtcagaggacgacgtgtgggataatgaccgtattctgacgcatttccacgacatctgc
gcacttttagcacacaaaacctaccgacagttacattgcttgtatgctcccggtgcggag
gcaggatcatcgttgacacagtcgctctcgggactttatcgtgttgctcgctggtgtatg
cacagcaccacgccgctggcgtccttaacagtattgacccatggtgcgtttcgcgtacag
gaagaggataatcccgaaccgacgctggcagcgttgtcgggcgcagtaaacgtgtttgcc
caagagctgcacccgaccgaagtacgattgatcgatatcgatgcgcagagcagtgatgag
aatctgaacttgctaacccagcgtctggccccgaaacaagaaacggtaatggcgctcagg
caggggatgctttacctgcgacgctttatcccgacacggctgttggcgcacttaccccct
caaacagggtgtataccgggcaacgtactgtggattatcggcggtgaaaaggggattggc
cgcatgatcggcgaagcgcttgctcagcgtgagggagtccgtgtggtactgagcagccgc
acaggttatcaccatgaagcggtgcagcaggacgcattagacgttatccactgcgacgtg
acgcaggcggaggcggttagagcttgtctggcaactctgctcgaacgctatggacggttg
gatggcgtgatttttgctgccgacgctaccaccacattgacactgcatcaattgagcgaa
tctgcgctacgcgacacgctaacggtgaaagaacggggtactgctaatgtgctgcatgcg
ttagcgcaacggaatctgctggatgagcgtctgctactgctgttctgtaactcgttggct
gccgtgaatgcggagattggccagacaggctatgctaccgccagcgcctatttggatgca
ctggcacagcaactgcgtacccgctacaaggtgaatgcgctcagtatcgggttggatgca
ttgcgtgagcagggcatgttgttggatgctataaacggcagtgaatacgatgtcttgcgt
ggactgcgcccattgatgacgggaacgttgctacaggcttataaacaacaaggggctgac
accagctactacgcgcgattatcccccgagtccgattggctgctggatgagcaccggata
tccggtatcgccacgctgccgggaaccggctatctggcgctggcgtatgaagctctgcgc
cattactttgtgcaagaccaaatctgcattgatgaattggtctttttggcaccgttgact
gtgatggacaactgcagtgttgacgtttttgttgacatttcacctaacgggcaaggagtt
agtgtcgaggtgaaatcaatgacggagcgctttagtggcacgttaacaacccatgccaga
ggcagggcgacgcgtctgatggtagacgataatgttgtgtgcgatctcacggggctgatg
cgcgagatgcacactatcactcctccaacaaaggaattatcgagcacgcacttccactat
gggccgcgctggcacagcgtacaacaactgtatggcaataccgcccagactcaggttttc
gcaacgctggccctgcccaccgttgccgctaatgatacgatcgcactgcaccctgcgctg
ttggacatcgccagcagtgttgtcgaacaactgcctggttttcatactgattcggtacct
ttcctttatcaggatttacgcctgtaccgcccgttgccgaacaccttacatgtggcgctg
actgtcaatcggcacgatgaggagggtgacagctacgctttcacgctctacgacatggca
ggcgagatggttgcccgctgtgcggcaatggtgaagcgcaaggtacagctccacatacaa
gatgtcgatgacgacacgcgactgcgcgtgcccagtgccgataactaccaactgcggctg
gccgctgagggggagggggcaggaaagctagcgttgtgccctacgccgcgcttagcgctg
ggggattcacaagtagagattgaggtactggccaccggactgaactttaaggatgtgctg
ttcaccacgggattgctccggcagcagccgggtgaggctccgctgcaattgggactggag
tgcgccggacgcattactcgcgtgggtaaaaatgtcactgaatttgccccgggagaggat
gttatggcggtgctaaacggtggttttgtccagtacgcacgggtagaaagcgattgcgta
gtgagaaaaccagcccattgtcgcatcgaacaggcggctgcgctgcctatcgcatacctc
accgcctattacgcactggtggtgcgcgctaatttgcaacccggagaacgagtattgatc
cacagtgcggcggggggcgttggcttggctgcgctacatattgccaaacgctgcggagca
cagattttcgccacagcaggtagcgagcagaaacgcgattacttgctttcgctaggcgta
catgccgtagctgattcacacgacgaacagttcgctgccactctgctgaccgcatcggac
ggacaggggatggatgtgatccttaactccctcacaggccgtctgcttgacgctagcctc
gcgctgctggcaccgctgggccgttttcttgagctgggcagcaaggacattgtggaagac
aaagcgctaccgatgcgtttcttcgcccaaggcggcacctttattccgattaattttcac
gcggcgcatggtgcgtttagtcgctacctgcaacagattgtcgcttggatagatgataac
acgctaccgctccttccatgcaaatccgtaccattgcccgaggttgcacgcgccttcgcc
accctgaccacgccgcagcatattggcaaggtggtggtaacgcatcgcactgcggcaggc
atggaccggctgaacgccatgatagcagaaaggcgcctcggcggctatgcgctcagcatg
agcaatgccgaggtgatgcgccaattgtggccgatactgaacactcgcagtccgtgggcg
caactgctgctctcacctcgggcgatcgatagattagcgcggggcaaccgggtggatcgc
ggtgtaccgtctgccgctaacgatacgattactcagcagacagtgaaaaagcggccccgt
ccggaaattggcgtgccttacagccccgcgacacgtgaagtggaacgcgtgctctgccaa
atcctggaagagtatctgggtctggatagagtaggcattgacgacaactatgccgaatta
ggggcaacctcactcgatatggtgcaactgagtgggcaaatggcgcgtcactatccgcaa
gtgagcgtggtgtcgctgtacaaccacgccaccgtgcgccagctggcgacgttttgccag
cccccggagggcgagtcaaatgcgccatcaccacagcctgcagtacagacgaatacgcgc
gcgaatcagatagcaaaacgtgctttgcaaattgcgaaaaatactgcgcgcagtcacacg
tctttgcattaa
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integrated database retrieval system
