Klebsiella aerogenes EA1509E: CCG31750
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Entry
CCG31750 CDS
T02447
Name
(GenBank) 2-isopropylmalate synthase (EC 2.3.3.13)
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
ear
Klebsiella aerogenes EA1509E
Pathway
ear00290
Valine, leucine and isoleucine biosynthesis
ear00620
Pyruvate metabolism
ear01100
Metabolic pathways
ear01110
Biosynthesis of secondary metabolites
ear01210
2-Oxocarboxylic acid metabolism
ear01230
Biosynthesis of amino acids
Module
ear_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
ear00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
CCG31750
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
CCG31750
Enzymes [BR:
ear01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
CCG31750
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GFIT
Motif
Pfam:
HMGL-like
LeuA_dimer
HCS_D2
C_LFY_FLO
IPMS_D2
Trp_syntA
Motif
Other DBs
NCBI-ProteinID:
CCG31750
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Position
3048592..3050163
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AA seq
523 aa
AA seq
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MSQQVIIFDTTLRDGEQALQASLSVKEKLQIAMALERMGVDVMEVGFPVSSPGDFESVQT
IARTIKNSRVCALARCVEKDIDVAAESLKVAEAFRIHTFIATSPMHIATKLRSTLDEVIE
RAIYMVKRARNYTDDVEFSCEDAGRTPIDDLARVVEAAIRAGATTINIPDTVGYTMPFEY
ANIISGLYERVPNIDKAIISVHTHDDLGIAVGNALAAVHAGARQVEGAMNGIGERAGNCA
LEEVIMAIKVRKDIMNVHTNINHHEIWRTSQTVSQICNMPIPANKAIVGTGAFAHSSGIH
QDGVLKNRENYEIMTPESIGLNQVQLNLTSRSGRAAVKHRMEEMGYKESDYNLDHLYDAF
LKLADKKGQVFDYDLEALAFINKQQEEPEHFRLDYFSVQSGSSDIATASIKLACGDDIKT
EAANGNGPVDAIYQAINRVTDYNIDLVKYGLSAKGHGKDALGQVDIVVEYNGRRFHGVGL
ATDIVESSAKAMVHVLNNIWRAAEVEKELQRQAQNKENNKETV
NT seq
1572 nt
NT seq
+upstream
nt +downstream
nt
atgagccagcaagtcattattttcgatacgaccttacgtgatggggaacaagcgttacag
gccagcctgagcgtgaaagagaagctgcagatcgccatggccctcgaacgtatgggcgtc
gatgtaatggaagtcggtttcccggtttcttccccgggcgattttgaatcggtacagacc
atcgctcgcaccatcaaaaatagccgcgtttgcgcgctggcgcgctgcgttgagaaagat
atcgacgtggcggcggaatccttaaaagtggcggaagcgttccgcatccacaccttcatc
gccacgtctccgatgcatatcgccaccaagctgcgcagcacgctggatgaagtcatcgaa
cgcgctatttatatggtgaaacgtgcgcgtaactataccgacgacgtggaattctcctgt
gaagacgcaggccgtacgccgatcgacgatctggctcgcgtcgttgaagcggctatccgc
gccggcgccacgaccattaatatcccggataccgtcggctacaccatgccattcgaatac
gccaacatcatcagcggcctgtatgaacgcgtaccaaacattgataaagcaattatttca
gtccacacccatgatgatttaggtatcgccgtcggcaacgccctcgccgccgtccatgct
ggcgctcgtcaggtagaaggcgcgatgaacggtatcggcgaacgcgccggtaactgcgcg
ctggaagaagtcatcatggcgatcaaggtgcgcaaagacatcatgaacgtgcacaccaat
atcaatcaccatgaaatctggcgtaccagccagaccgtcagccaaatctgcaatatgccg
atcccggctaacaaagctatcgtcggtaccggcgccttcgcccactcttccggtattcat
caggatggcgtgctgaagaaccgcgaaaactacgaaatcatgaccccggaatccatcggc
ctgaaccaggtacagctgaacctgacttcacgctccggtcgcgcggcggtgaaacaccgc
atggaagagatgggctacaaagagagcgactacaacctggatcatctgtatgacgccttc
ctgaagctggcggataaaaaaggccaggtcttcgactacgacctggaagcgctggcgttc
atcaataaacagcaggaagagccagagcattttcgtctggactacttcagcgtccagtct
ggctccagcgatattgctaccgcctctatcaagctggcctgcggtgatgacatcaaaacc
gaagccgccaacggcaacggcccggttgacgctatctaccaggcaatcaaccgtgtgaca
gactacaacatcgacttagtgaagtatggcttaagcgccaaaggccacggcaaagatgcg
ctgggtcaggtggatattgtcgtggaatacaacggtcgccgcttccacggcgtcggcctg
gcgaccgatatcgtcgaatcttcagcaaaagcgatggtacatgtgcttaacaacatctgg
cgcgccgccgaagtcgaaaaagaattgcaacgccaggctcagaataaagagaacaacaag
gaaaccgtgtaa
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