Klebsiella aerogenes EA1509E: CCG33948
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Entry
CCG33948 CDS
T02447
Name
(GenBank) Phosphoribosylformylglycinamidine synthase, synthetase subunit (EC 6.3.5.3) / Phosphoribosylformylglycinamidine synthase, glutamine amidotransferase subunit (EC 6.3.5.3)
KO
K01952
phosphoribosylformylglycinamidine synthase [EC:
6.3.5.3
]
Organism
ear
Klebsiella aerogenes EA1509E
Pathway
ear00230
Purine metabolism
ear01100
Metabolic pathways
ear01110
Biosynthesis of secondary metabolites
Module
ear_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
ear00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
CCG33948
Enzymes [BR:
ear01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
CCG33948
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Paralog
Gene cluster
GFIT
Motif
Pfam:
GATase_5
FGAR-AT_PurM_N-like
AIRS_C
FGAR-AT_N
FGAR-AT_linker
MAT1-1-2
Motif
Other DBs
NCBI-ProteinID:
CCG33948
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Position
5307604..5311491
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AA seq
1295 aa
AA seq
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MMDILRGSPALSAFRINKLLARFQAANLPVSTLYAEYVHFADLSAPLSDEERERLVRLLK
YGPSLSSHTPTGKLLLVTPRPGTISPWSSKATDIAHNCGLSQVVRLERGVAYYVEAQGLS
DAQWDAVAAELHDRMMESVFTELEEGEKLFAHHQPTPVASVDLLGQGRQALIDANLRLGL
ALADDEIDYLQDAFVKLGRNPNDIELYMFAQANSEHCRHKIFNADWIIDGQQQPKSLFKM
IKNTFEKNPEYVLSAYKDNAAVMEGSEVGRYFADYQTGRYDFHQEPAHILMKVETHNHPT
AISPWPGAATGSGGEIRDEGATGRGAKPKAGLVGFSVSNLRIPGFEQPWEEDFGKPERIV
TALDIMTEGPLGGAAFNNEFGRPALNGYFRTYEEKVTSHNGEELRGYHKPIMLAGGIGNI
RGEHVQKGEITVGAKLIVLGGPAMNIGLGGGAASSMASGQSDADLDFASVQRDNPEMERR
CQEVIDRCWQLGDANPILFIHDVGAGGLSNAMPELVSDGGRGGKFQLRDILSDEPGMSPL
EIWCNESQERYVLAVAPEQLPLFEELCRRERAPYAVIGEATAEQHLSLSDSHFNDRPIDL
PLDVLLGKTPKMTRDVQTLKAQGSELDRQPMTIADAVNRVLHLPTVAEKTFLVTIGDRTV
TGMVARDQMVGPWQIPVANCAVTTASLDSYYGEAMAMGERAPVALLDFAASARLAVGEAL
TNIAATQIGELNRVKLSANWMAAAGHPGEDAGLYEAVKAVGEELCPALGLTIPVGKDSMS
MKTRWQEGSEQREMTSPLSLVISAFARVEDVRGTVTPQLSTEDNALLLIDLGKGRNALGA
TALAQVYRQLGDQPADVRDVAQLKGFWDAMQALVAQRKLLAYHDRSDGGLLVTLAEMAFA
GHCGVTADIAALGDDRLAALFNEELGAVIQVRAADREAVEALLAMNGLADCVHYLGQATA
GDRFVITADGQPLFSESRTTLRMWWAETTWQMQRLRDNPECADQEHQAKSNDSDPGLNVK
LSFDINEDVAAPYIATGARPKVAVLREQGVNSHVEMAAAFHRAGFDAIDVHMSDLLAGRT
GLGDFHALVACGGFSYGDVLGAGEGWAKSILFNERVRDEFATFFHRPQTLALGVCNGCQM
MSNLRELIPGSDLWPRFVRNHSDRFEARFSLVEVTQSPSLLLQGMAGSMMPIAVSHGEGQ
VEVRDSAHLAALESKGLVALRFVDNFGKVTQTYPANPNGSVNGITAVTSESGRATIMMPH
PERVFRTVSNSWHPENWGEDSPWMRIFRNARKQLG
NT seq
3888 nt
NT seq
+upstream
nt +downstream
nt
atgatggatattttgcgtggttcacctgcactgtcggcattccgtatcaacaaactgctg
gcacgttttcaggcggccaacctgccggttagcaccttatacgcggagtatgttcacttt
gccgacctgagcgccccgctaagcgatgaggagcgcgaaagactggtcagactgcttaaa
tatggcccaagcctcagcagccatacgccaaccggtaaattactgctcgtcacccctcgc
cccggcactatctccccctggtcctccaaagctaccgacatcgcccataactgcggttta
tcgcaggtcgtgcggctggaacgcggcgtggcgtactacgttgaagcacagggtctgagc
gatgcgcagtgggacgccgttgcggcggagctgcacgatcgcatgatggagagcgttttc
actgagctggaagagggagagaagctgtttgctcaccatcagccgacaccggtggccagc
gtggacctgttgggccagggacgtcaggcgctgattgacgccaacctccgtctggggctg
gcgctggccgatgacgaaatcgactacctgcaggacgcattcgttaagcttggccgcaat
ccgaacgacattgaactgtatatgttcgcgcaggccaactcggaacattgccgccacaaa
atttttaacgccgactggattatcgacggccaacaacagccgaagtcgctgtttaaaatg
attaaaaataccttcgagaaaaacccggaatatgtgctgtctgcctataaagacaacgcc
gcggtaatggaaggttccgaagtcggacgctatttcgccgactaccagaccgggcgctat
gacttccatcaggagccggcgcacattctgatgaaagttgaaactcacaaccacccgacg
gcgatttcgccgtggccgggcgccgcaaccggctccggcggcgagatccgcgacgaaggc
gccacggggcgcggcgcgaagccgaaagcgggtctggtcggcttctcggtgtctaacctg
cgtatcccgggttttgaacagccgtgggaagaggatttcggtaaacctgagcgtatcgtg
accgcgctggatatcatgaccgaaggcccgttgggcggcgcggcgtttaacaacgaattt
ggtcgtccggcgctgaatggctacttccgtacctatgaagagaaagtgaccagccacaat
ggcgaagagctgcgcggctatcacaaaccgatcatgctggcgggcggtattggcaacatc
cgcggcgagcacgtccagaagggcgaaatcaccgttggcgccaagcttatcgtgctgggc
ggcccggcgatgaacattggtctcggcggcggcgcggcgtcatccatggcttccggccag
tctgatgccgatctggatttcgcctctgtacagcgcgacaacccggaaatggagcgccgc
tgtcaggaagtgatcgaccgctgctggcagctgggcgatgcgaacccgattctgtttatc
cacgacgttggcgcgggcggtctctctaacgccatgccggagctggtgagcgatggcggc
cgcggcggaaaattccagctgcgcgatatcctcagcgatgagccgggcatgagcccgctg
gagatttggtgtaacgaatcccaggagcgttacgttctggcggtcgcgccggaacagctg
ccgctgtttgaagagctgtgccgccgcgagcgcgcgccttatgcggtgatcggcgaagcc
acggcggagcaacaccttagcctgagcgacagccactttaacgatcggccgatcgacctg
ccgctggacgtcctgctcggcaaaacgccgaaaatgacgcgtgacgtgcaaacgctgaaa
gcgcagggcagcgagctggatcgtcaaccaatgacgattgccgatgcggttaaccgcgtg
ctgcatctgccgacggtggctgagaaaaccttccttgtgaccatcggcgatcgcaccgtg
accggtatggtggcgcgtgaccagatggtggggccgtggcagatcccggtcgccaactgc
gcggtgaccaccgccagcctcgatagctactacggcgaagcgatggcgatgggtgaacgc
gcaccggttgcgctgctcgactttgccgcctctgcccgcctggcggtcggcgaagcgttg
acaaacatcgccgctacgcagattggcgaactcaaccgcgtcaaactgtcggcaaactgg
atggcggcagccggtcacccgggtgaagacgccggcctgtatgaggcggtaaaagcagtc
ggtgaagaactgtgtccagcgctgggcctgactatcccggtgggtaaagactcaatgtcg
atgaaaacccgctggcaggaaggaagcgagcagcgcgaaatgacctcgccgctgtcgctg
gtgatctccgcatttgcccgcgttgaagacgtgcgcggcaccgtgactccgcaactctct
acggaagataacgccctgctgctgatcgatctcggcaaaggtcgtaacgcgctgggcgcc
accgcgctggcgcaggtctatcgccagctaggcgaccagccggccgacgtgcgtgatgtc
gcgcagctgaaaggcttctgggacgcgatgcaggcactggtggcgcagcgtaaactgctg
gcctaccacgaccgctccgatggcggactgttagtgacgctggcggaaatggcgttcgcc
ggtcactgcggcgtaactgccgatatcgccgcgctgggcgacgatcgtctggcggcgctg
ttcaacgaagaattgggcgcggtgattcaggttcgcgccgcggatcgcgaagcggtggaa
gcgctgctggcgatgaatggtctggcagattgcgtgcactacttaggccaggcgacggca
ggcgatcgttttgttatcaccgccgacggtcagccgctgttcagcgaaagccgcaccacg
ctgcgtatgtggtgggcggagaccacctggcagatgcagcgcctgcgcgataacccggaa
tgcgccgatcaggagcaccaggcgaagtctaacgatagcgacccgggccttaacgttaag
ctgtcgtttgatatcaatgaagatgttgctgcgccgtatattgcgaccggcgcgcgcccg
aaagtggctgtgctgcgcgagcagggggttaactcccatgttgaaatggccgccgctttc
catcgcgccggcttcgatgccatcgacgtgcatatgagcgatctgctggcgggtcgtact
ggtcttggcgacttccatgcgctggtggcctgcggcggtttctcctacggtgacgtactg
ggggcaggcgaaggttgggcgaaatcgattctgttcaacgaacgcgtacgcgatgagttc
gccactttcttccatcgcccgcagacgctggcgctgggcgtgtgtaacggttgtcagatg
atgtccaacctgcgtgagctgatccctggaagcgacctgtggccgcgcttcgtacgcaac
cactctgaccgctttgaagcgcgtttcagcctggttgaagtcacccagagcccatcgctg
ctgctgcagggcatggccggttcgatgatgccgattgccgtttctcacggcgaagggcag
gtggaggtgcgggacagcgcgcacctggccgcgcttgaaagcaaaggcctggtggcgcta
cgtttcgtcgataacttcggcaaagtgacgcaaacctatccggcgaacccgaacggctcg
gtgaacggcattaccgcggtgaccagcgaaagcggtcgcgcgacgatcatgatgccgcac
ccggaacgcgtcttccgtaccgtcagtaactcctggcacccggaaaactggggtgaagac
agcccatggatgcgtatcttccgcaacgcgcgtaagcaactgggttaa
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