KEGG   Enterobacter adelaidei: AAHF05_20775
Entry
AAHF05_20775      CDS       T10740                                 
Symbol
cysG
Name
(GenBank) siroheme synthase CysG
  KO
K02302  uroporphyrin-III C-methyltransferase / precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase [EC:2.1.1.107 1.3.1.76 4.99.1.4]
Organism
eax  Enterobacter adelaidei
Pathway
eax00860  Porphyrin metabolism
eax01100  Metabolic pathways
eax01110  Biosynthesis of secondary metabolites
eax01120  Microbial metabolism in diverse environments
eax01240  Biosynthesis of cofactors
Module
eax_M00846  Siroheme biosynthesis, glutamyl-tRNA => siroheme
eax_M00924  Cobalamin biosynthesis, anaerobic, uroporphyrinogen III => sirohydrochlorin => cobyrinate a,c-diamide
Brite
KEGG Orthology (KO) [BR:eax00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00860 Porphyrin metabolism
    AAHF05_20775 (cysG)
Enzymes [BR:eax01000]
 1. Oxidoreductases
  1.3  Acting on the CH-CH group of donors
   1.3.1  With NAD+ or NADP+ as acceptor
    1.3.1.76  precorrin-2 dehydrogenase
     AAHF05_20775 (cysG)
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.107  uroporphyrinogen-III C-methyltransferase
     AAHF05_20775 (cysG)
 4. Lyases
  4.99  Other lyases
   4.99.1  Sole sub-subclass for lyases that do not belong in the other subclasses
    4.99.1.4  sirohydrochlorin ferrochelatase
     AAHF05_20775 (cysG)
SSDB
Motif
Pfam: TP_methylase NAD_binding_7 CysG_dimeriser Sirohm_synth_M Radical_SAM
Other DBs
NCBI-ProteinID: XGV91193
LinkDB
Position
4262308..4263681
AA seq 457 aa
MDHLPIFCQLRNRDCLLVGGGDVAERKARLLLEAGARLTVNALDFAPQFEVWAQAGMLTL
QQGEFNESLLDTCWLTIAATDDDEVNQRVSDACEVRRIFCNVVDAPKEASFIMPSIIDRS
PLMIAVSSGGRSPVLARLLREKLEAVLPQHLGQIAHYAGQLRSRVKQTFATVAERRRFWE
KFFVNDRLAQSLANQDTKAVEETTEQLLAEPLDHRGEVVLVGAGPGDAGLLTLKGLQQLQ
QADTVVYDRLVSDDIMNLVRRDADRVFVGKRAGYHCVPQEEINQILLREAQKGKRVVRLK
GGDPFIFGRGGEELETLCDAGIPFSVVPGITAASGCSAYSGIPLTHRDYAQSVRLVTGHL
KTGSELDWHNLAAEKQTLVFYMGLNQAATIQAKLLEHGMDADMPVALVENGTAITQRVVN
GVLTQLGELAQQVESPALIVVGRVVELRGKLNWFSNH
NT seq 1374 nt   +upstreamnt  +downstreamnt
gtggatcacttgccgattttttgtcaattacgcaaccgcgactgcctgctcgtgggcggc
ggcgatgtggccgaacgcaaagcgcgcctgctgttagaagcgggtgcccgtttgaccgtc
aacgccctcgactttgccccacagtttgaggtctgggcccaggcaggaatgctcacgctg
cagcagggtgagtttaatgaatccctgctggatacctgctggctgacgattgccgcaacg
gacgacgatgaagtgaaccaacgcgtgagcgatgcctgtgaggtacgccgtatcttctgc
aacgtggtggatgcgccgaaagaagccagcttcatcatgccgtcgattatcgaccgttcc
ccgctgatgattgcggtgtcgtccggtggccgctccccggtacttgctcgcctgctgcgg
gaaaaactggaggctgtgctgccacagcatcttggtcagattgcgcattatgccgggcag
ctgcgttcacgcgtgaagcaaaccttcgcaaccgtagctgagcgacgtcggttctgggaa
aaattctttgtcaacgacaggctggcgcagtcgctggcgaatcaggacacgaaagccgtt
gaagagacgaccgaacagttgctggccgaaccgcttgatcaccgcggtgaagtggtgctg
gtgggtgcagggccgggagatgcaggcttgctgacgctgaaaggtctccagcagctccag
caggccgatactgtggtttacgatcgcctggtctccgatgacatcatgaacctggttcgc
cgcgacgccgaccgtgttttcgtgggcaaacgcgcgggctaccattgcgtgccgcaggaa
gagattaaccagatcctgctgcgcgaggcgcaaaagggaaaacgcgtggtgcgtctgaaa
ggtggtgatccgtttatctttggccgtggcggtgaagagctggaaaccctgtgtgacgcg
ggtattccgttctctgtcgtgcccggcattacggcggcatccggttgctcagcctactca
ggcattccgctgacacaccgggactacgctcagagcgtgcgtctggtgacgggccacctg
aaaaccggcagcgagctggactggcataacctggccgcagaaaaacagacgctggtgttc
tatatggggctgaaccaggccgccacaattcaggcgaaactgctggagcacggcatggat
gcagatatgcccgtcgcactggtggaaaacggtaccgccattacgcagcgcgtggtaaat
ggcgtgctgacgcagcttggtgaactggcgcaacaggttgaaagcccggcactgattgta
gtgggtcgcgtggtggaactgcgcggtaaactcaactggttctccaaccactga

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