Erwinia amylovora ATCC 49946: EAM_0642
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Entry
EAM_0642 CDS
T01199
Symbol
thrA
Name
(GenBank) bifunctional aspartokinase/homoserine dehydrogenase I [includes: aspartokinase I; homoserine dehydrogenase I]
KO
K12524
bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:
2.7.2.4
1.1.1.3
]
Organism
eay
Erwinia amylovora ATCC 49946
Pathway
eay00260
Glycine, serine and threonine metabolism
eay00261
Monobactam biosynthesis
eay00270
Cysteine and methionine metabolism
eay00300
Lysine biosynthesis
eay01100
Metabolic pathways
eay01110
Biosynthesis of secondary metabolites
eay01120
Microbial metabolism in diverse environments
eay01230
Biosynthesis of amino acids
Module
eay_M00016
Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
eay_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
eay_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:
eay00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
EAM_0642 (thrA)
00270 Cysteine and methionine metabolism
EAM_0642 (thrA)
00300 Lysine biosynthesis
EAM_0642 (thrA)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
EAM_0642 (thrA)
Enzymes [BR:
eay01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
EAM_0642 (thrA)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
EAM_0642 (thrA)
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Gene cluster
GFIT
Motif
Pfam:
Homoserine_dh
AA_kinase
ACT_9
NAD_binding_3
ACT_7
ACT
Sacchrp_dh_NADP
Motif
Other DBs
NCBI-ProteinID:
CBJ45317
LinkDB
All DBs
Position
718410..720872
Genome browser
AA seq
820 aa
AA seq
DB search
MRVLKFGGTSVANAERFLRVADILESNAQQGQVATVLSAPAKITNHLVAMIEKTISGQDA
SANISDAERIFAALLQGLTDAQPGFAYDRLKAVVDQEFLQLKQVLHGIALLGQCPDSVNA
AIICRGEKLSIAIMEGVLQARGHGVSVINPVEQLLAIGHYLESTVDIAESTRRIAARQIP
ASDMVLMAGFTAGNEHGELVVLGRNGSDYSAAVLAACLRADCCEIWTDVDGVYTCDPRQV
PDARLLKSMSYQEAMELSYFGAKVLHPRTIAPIAQFQIPCLIKNTGNPQAPGTLIGGNGS
NDDNPVKGITNLNNMAMFNVSGPGMKGMVGMAARVFAAMSRSGISVVLITQSSSEYSISF
CVSQSDLPRARRVLEEEFYLELKNGLLEPLDVMEQLAVISVVGDGMRTLRGISAKFFSAL
ARANINIVAIAQGSSERSISVVVNNDQAITGVRVVHQMLFATDQVIEVFVIGVGGVGAAL
IEQLHRQQIWLKNKHIDLRVCGIANSRALLTNVHGIPLDSWQDRLKAAQQPFDLGRLNRL
VKEYHLLNPVIVDCTSSQQVADRYADFLADGFHVVTPNKKANTSSYNYYQQMRTAAAKAR
RKFLYDTNVGAGLPVIENLQNLLNAGDELISFSGILSGSLSFIFGKLDEGVSLSDATQMA
REMGFTEPDPRDDLSGMDVARKLLILAREAGYQLELSDIEIEAVLPPELTAIADVDEFMA
RLPELNEGFAARVSSARDAGKVLRFVGAIEESGACRVKIAAVDGNDPLYKVKNGENALAF
YSRYYQPIPLVLRGYGAGNDVTAAGVFADLLRTLSWKLGV
NT seq
2463 nt
NT seq
+upstream
nt +downstream
nt
atgcgagtgctgaaattcggtggaacctcggtagccaatgcggaacgttttctgcgtgtg
gctgacattttggaaagcaatgcacaacagggacaggttgctaccgtgttgtccgcgccg
gcaaaaattaccaaccatctggtggcaatgattgagaaaaccattagcggccaggatgct
tcagcgaatatcagcgatgcagagcgtattttcgccgcgctgttgcaggggctgaccgac
gcccagccggggtttgcttatgaccgtctgaaagcggtggtggaccaggaattcctccag
ctcaaacaggtgctgcatggtattgcgctgctggggcagtgcccggacagcgtcaatgcg
gccattatctgccggggtgaaaagctctcaatcgccataatggaaggtgtgttgcaggcg
cgcggccacggggttagcgtgattaatccggtcgagcagctgttggccatcggccattat
ctggaatccaccgttgatattgccgaatccacccgccgtatcgccgcccgccagatcccg
gccagtgatatggtgctgatggccggctttaccgccggtaatgaacatggagaactggtg
gtgctggggcgtaatggctcagattactctgcggcggtgctggcagcctgtctgcgcgct
gactgttgcgaaatctggaccgatgttgacggcgtgtacacctgtgacccgcgtcaggta
ccggatgcgcggctgctgaagtcgatgtcctatcaggaagcgatggagctttcctatttc
ggcgctaaagttcttcacccgcgcactatcgctcctatcgcccagttccagatcccctgt
ctgatcaaaaataccggcaatccgcaggcccccggaaccctgataggcggtaacggcagc
aatgatgacaacccggtaaagggcatcactaacctcaacaatatggcgatgttcaacgtc
tccggcccggggatgaagggcatggtcggcatggcggcacgcgtgtttgccgccatgtca
cgcagcggaatttcggtagtgctgatcacccaatcctcctcggaatacagcattagcttc
tgcgtatcgcagagcgatctgccgcgtgcgcgtcgggtgctggaagaggagttctatctg
gagttaaaaaacggcctgctggaacctttggatgttatggagcagctggcggtgatttcg
gtagtgggcgatggtatgcgcactctgcgcggcatctccgccaagttcttttcagcgctg
gcgcgggccaacattaatatcgtcgctatcgcccagggatcgtccgagcgttccatctcg
gtggtggtcaacaatgatcaggcgatcaccggcgtgcgcgtggttcatcagatgctgttt
gccaccgaccaggtgatcgaagtctttgtgatcggcgttggcggcgtgggtgctgcgctg
atcgaacagctgcatcgccaacaaatctggttgaaaaataaacacatcgatctgcgtgtc
tgtggcatagccaactcgcgggcgttgctgactaacgtgcacggcatcccgctggatagc
tggcaggatcggctaaaagcggcgcaacaaccgtttgatcttgggcggcttaatcgcctg
gtgaaagagtaccacctgctcaacccggtgattgtcgactgtacttccagccagcaggtg
gcggatcggtacgctgatttcctcgctgacggcttccatgtggtgacgccgaacaaaaag
gccaatacgtcatcgtacaattactatcagcaaatgcgaacggcagcggcaaaagcgcgc
cgcaaattcctctacgataccaatgtgggtgccggtctgccggttatcgagaacctgcaa
aatctgctgaatgcgggggatgaattgatcagcttctccggcatcctttccggttccctg
tcgtttattttcggcaagctggatgaaggcgtttcgctgtctgatgccacccaaatggcg
cgtgaaatgggctttaccgagccggatccgcgtgacgatttgtccggtatggacgtggcg
cgtaagctgctgatcctcgcgcgcgaagcaggttatcagctggagctaagcgatatagaa
attgaagcggtgctgccgccagagcttaccgccattgccgatgttgacgagtttatggcg
cgtttgccggagctgaacgaaggctttgccgcgcgggtgtccagcgcccgtgatgccgga
aaagtgttacgttttgttggtgccattgaggaaagcggggcgtgcagggttaaaatcgct
gctgttgacggtaacgatccactgtataaagtgaaaaatggtgaaaatgcgctggcgttc
tatagccgttattaccagccgatcccactggtgctgcgcggttacggcgccggtaatgat
gtgaccgcagcgggcgtatttgccgatctgttacgtacactgtcgtggaagttgggagtt
taa
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