Aromatoleum aromaticum: ebA4757
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Entry
ebA4757 CDS
T00222
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
eba
Aromatoleum aromaticum
Pathway
eba00290
Valine, leucine and isoleucine biosynthesis
eba00660
C5-Branched dibasic acid metabolism
eba01100
Metabolic pathways
eba01110
Biosynthesis of secondary metabolites
eba01210
2-Oxocarboxylic acid metabolism
eba01230
Biosynthesis of amino acids
Module
eba_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
eba00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
ebA4757 (leuC)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
ebA4757 (leuC)
Enzymes [BR:
eba01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
ebA4757 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
ebA4757 (leuC)
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Motif
Pfam:
Aconitase
Motif
Other DBs
NCBI-ProteinID:
CAI08816
UniProt:
Q5P1J8
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All DBs
Position
2815492..2816901
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AA seq
469 aa
AA seq
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MEAQTLYEKLWSSHVVHQEADGTALIYIDRHLIHEVTSPQAFEGLKLAGRKPWRVSSIVA
TADHNTPTDHWERGILDPVSRQQVETLDANIREVGALAYFPFRDARQGIVHVIGPEIGAT
LPGMTVVCGDSHTSTHGAFACLAHGIGTSEVEHVLATQCLLQKRSKTMLVRVDGELGRGV
SAKDIALAIIGRLGTAGGTGYAIEFGGSAIRALSMEGRMTICNMAIEAGARAGLVAVDQT
TIDYLRDKPLAPKGQAWEQAVAYWRTLKTDDGAKFDKIVELDAAQIQPQVTWGTSPEMVE
TVSGRVPDPAGIGDPVRREGIERALKYMGLAPNTPISEIPVDQVFIGSCTNSRIEDLREA
ASVAKGRSKAPSVKRVLVVPGSGLVKRQAEAEGLHEVFLAAGFEWREPGCSMCLAMNADR
LEPGEHCASTSNRNFEGRQGAGGRTHLVSPAMAAAAAVVGHFIDVRELA
NT seq
1410 nt
NT seq
+upstream
nt +downstream
nt
atggaagcccaaacgctgtacgaaaagctctggtccagtcacgtcgttcaccaggaggcg
gacggcacggcgctgatctatatcgaccgccacctgatccacgaggtgaccagcccgcag
gctttcgaaggcctgaagcttgccgggcgcaagccgtggcgcgtcagctcgatcgttgcg
acggccgaccacaacacgccgaccgaccactgggaacggggcattctagatcccgtctcg
cggcaacaggtcgaaacgctggacgcgaacatccgcgaggtgggcgcactggcctacttt
cctttcagggacgcgcgccagggcatcgtccatgtgatcgggcccgagatcggcgcgacg
ctccccggcatgacggtcgtgtgcggcgactcccatacgtcgacgcacggtgccttcgcc
tgtctcgcgcacggaatcgggacctcggaagtcgagcatgtgcttgcgacccagtgtctg
ttgcagaagcgttccaagacgatgctggtccgggtggacggcgaactgggccgcggcgta
tcggcgaaagacattgcgctggcgatcatcggccgcctcggtaccgcgggcggaaccggc
tacgcgatcgagttcggcggcagtgcgatccgcgcgctgtcgatggaagggcggatgacg
atctgcaacatggcgatcgaagccggcgcacgcgccggtctggtcgcggtcgaccagacg
acgatcgactacctgcgcgacaagccgctcgcgccgaaaggccaggcgtgggagcaggcg
gtcgcttactggcgcacgctgaaaacggacgatggcgcgaaattcgacaagatcgtcgaa
ctcgacgccgcgcagatccagccgcaagtcacgtgggggacttccccggagatggtcgag
acggtttcggggcgcgtgcccgatccggccggcatcggcgatccggtcaggcgcgaaggc
atcgagcgcgcgctgaaatacatgggtctcgcgccgaacacgccgatcagcgagattccc
gtcgatcaggtgttcatcggttcctgtaccaattcccgcatcgaggacctgcgcgaggcg
gcgtcggtcgcgaaggggcgcagcaaggcgccgagcgtcaagcgcgtgctggtcgtgccc
ggttcgggtctggtcaagcgtcaggccgaggccgagggattgcacgaggtgttcctcgct
gccggattcgagtggcgcgagccggggtgttcgatgtgcctcgcgatgaatgccgaccgg
ctcgagcccggcgaacactgcgcttcgacgtcgaatcgcaacttcgagggccggcaggga
gccggcggccggacgcatctcgtcagcccggcgatggctgccgcggcagcggtcgtcggc
catttcatcgacgtgcgcgagcttgcgtga
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