Aromatoleum aromaticum: ebA4760
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Entry
ebA4760 CDS
T00222
Symbol
leuB
Name
(GenBank) 3-isopropylmalate dehydrogenase (Beta-IPM dehydrogenase)
KO
K00052
3-isopropylmalate dehydrogenase [EC:
1.1.1.85
]
Organism
eba
Aromatoleum aromaticum
Pathway
eba00290
Valine, leucine and isoleucine biosynthesis
eba00660
C5-Branched dibasic acid metabolism
eba01100
Metabolic pathways
eba01110
Biosynthesis of secondary metabolites
eba01210
2-Oxocarboxylic acid metabolism
eba01230
Biosynthesis of amino acids
Module
eba_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
eba00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
ebA4760 (leuB)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
ebA4760 (leuB)
Enzymes [BR:
eba01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.85 3-isopropylmalate dehydrogenase
ebA4760 (leuB)
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GFIT
Motif
Pfam:
Iso_dh
LolA_3
Motif
Other DBs
NCBI-ProteinID:
CAI08818
UniProt:
Q5P1J6
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All DBs
Position
2817646..2818698
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AA seq
350 aa
AA seq
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MKICILPGDGIGPEITAEAVRVIEALDLKFEMEEALLGGAAVDATGDPYPEATRKLAREA
DAVLLGAVGGPKWDTLPREQRPERGLLGIRKDLGLFANLRPAILYPELANASSLKPEVVA
GLDILIVRELTGDIYFGQPRGLEVRDGERFGFNTMHYSESEIRRIGRVAFEAARKRNRRL
CSVDKMNVLETTQLWRDVMIELAAEYPDVELSHMLVDNAAMQLVRAPKQFDVMVTGNMFG
DILSDEASMLTGSIGMLPSASLDANNKGLYEPSHGSAPDIAGQGIANPLATILSVAMMLR
YTFNQENGALRIENAVKKVLAQGLRTGDIFEPGTTKVGTKQMGDAVLAAL
NT seq
1053 nt
NT seq
+upstream
nt +downstream
nt
atgaagatttgcattctgccgggcgacggcatcgggccggagatcacggccgaggcggtg
cgcgtgatcgaggcgctggacctgaagttcgagatggaagaggccctgctgggcggcgcc
gcggtcgatgcgaccggcgatccgtatccggaggcgacgcgcaagctcgcccgcgaggcc
gacgcggtgctgctcggcgccgtcggcggcccgaagtgggacacgttgccgcgcgaacag
cgcccggaacgcggcctgctcggcatccgcaaggatctcggcctgttcgcgaacctgcgt
ccggcgatcctgtaccccgaactcgcgaatgcgtcgtcgctgaagccggaggtggtggca
gggctcgacatcctgatcgtgcgcgaactcaccggcgacatctatttcggccagccgcgc
gggctggaggttcgtgacggcgagcgtttcggcttcaacacgatgcactacagcgagtcc
gagattcgccgcatcggccgggtcgcgttcgaggccgcgcgcaagcgcaacaggcggctg
tgctcggtggacaagatgaacgtgctcgagacgacgcagctgtggcgcgacgtgatgatc
gaactggccgccgagtatccggacgtcgaactcagccacatgctggtcgacaacgccgcg
atgcaactcgtgcgcgcgccgaagcagttcgacgtgatggtcaccggcaacatgttcggc
gacatcctctccgacgaggcctcgatgctcaccggctcgatcggcatgctgccgtcggcc
tcgctggacgcgaacaacaaggggttgtacgagccgtcgcacggctcggcgcccgacatc
gccggccagggcattgccaatccgctggcgacgatcctttccgtcgcgatgatgctgcgc
tacacgttcaatcaggaaaatggggcgctccgcatcgagaatgcggtgaagaaggtgctg
gcgcagggcctgcgcaccggcgacattttcgagccgggcacgacgaaggtcggtacgaag
caaatgggcgacgccgtgttggcggcactctga
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