Enterobacteriaceae bacterium ENNIH2: C2U52_02940
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Entry
C2U52_02940 CDS
T05417
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
ebc
Enterobacteriaceae bacterium ENNIH2
Pathway
ebc00300
Lysine biosynthesis
ebc00550
Peptidoglycan biosynthesis
ebc01100
Metabolic pathways
ebc01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
ebc00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
C2U52_02940
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
C2U52_02940
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
C2U52_02940
Enzymes [BR:
ebc01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
C2U52_02940
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
LpxD
BBMV_Gp1_N
Motif
Other DBs
NCBI-ProteinID:
AUV05312
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Position
complement(240763..242121)
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AA seq
452 aa
AA seq
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MISVTLSQLSGILHGELHGADATIEAVTTDTRKLTSGCLFVALKGERFDAHDFADKAKEG
GAGALLVSRKLDIDLPQLVVKDTRLAFGELAAWVRQQVPARVVALTGSSGKTSVKEMTAA
ILSECGNTLYTAGNLNNDIGVPMTLLRLTNEHQYAVIELGANHQGEIAWTVSLTRPEAAL
VNNLAAAHLEGFGSLAGVAKAKGEIYTGLPANGIAIMNADNNDWLNWQNIIGDRKVWRFS
PNAANSDFTATNIHVTSHGTEFTLQTPTGGIDVTLPLPGRHNIANALAATALAMAVGAPH
DAVKKGLANLKAVPGRLFPVQLGENQLLLDDSYNANVGSMTAAAHVLAEMPGYRVMVVGD
MAELGDESEACHIQVGETAKAVGIDRVLSVGKLSKAISDASGVGEHFDDKAAMIARLEAL
IAEKQIITILVKGSRSAAMEEVARALQEKRAC
NT seq
1359 nt
NT seq
+upstream
nt +downstream
nt
atgattagcgtaacgcttagccagctcagcggcattttgcatggcgaactgcatggtgca
gacgcaaccattgaggcggtcactacggacacccgcaagctgacctctggttgcctgttt
gtggcgctgaaaggcgaacgtttcgatgcccacgatttcgctgataaagcaaaagagggc
ggtgctggcgcgctgttagtcagtcgcaaactggatatcgacctgccgcaactggtggtg
aaggatacccgtctcgcctttggcgaactggcagcctgggttcgccagcaggttcctgct
cgcgttgtggcgctgaccggctcgtctggcaaaacctcggtgaaagagatgacggccgcc
atcctcagcgaatgtggcaatacgctctataccgccgggaacctgaacaatgacatcggt
gtgccgatgaccctgctgcgcctgacaaatgaacatcagtatgcagtgattgaacttggc
gctaatcaccagggtgaaatcgcctggactgtgtcgctgacccgcccggaagcggcgctg
gttaacaatcttgcggcagcgcatcttgaagggtttggctctctggccggggtggcaaag
gctaaaggcgagatttataccggcctgcctgccaacggcatcgccattatgaatgccgat
aacaatgactggctgaactggcaaaacatcattggcgatcgcaaagtctggcgtttctcg
ccaaatgccgccaacagcgattttaccgcgaccaatattcatgtgacctcccacggtact
gaatttacgctgcaaaccccaacgggcggtattgatgtcacgttgccattacctgggcgc
cacaatatcgcgaatgcgctggccgcaaccgcgctggcgatggcggtaggggcaccgcat
gacgcagtgaaaaaaggtctggcaaatctgaaagctgttccggggcgtcttttcccggtg
caacttggagaaaaccaattactgctggacgacagctacaatgcgaacgtggggtcgatg
acggcggcagcgcatgtgttagctgaaatgccaggctatcgggtcatggtggtcggcgac
atggcggaattgggtgatgaaagcgaggcgtgtcacattcaggtgggtgaaacggcaaaa
gctgttggtatcgaccgtgtgttaagcgtcggcaagctcagtaaagccatcagtgatgcc
agtggcgttggcgagcattttgatgataaggcggcaatgattgcgcgtttagaggcactg
attgccgagaagcaaattattaccattttggtgaaaggttcacgtagtgccgccatggaa
gaggtcgcacgcgcattacaggagaaaagggcatgttag
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