KEGG   Enterobacteriaceae bacterium ENNIH2: C2U52_14385
Entry
C2U52_14385       CDS       T05417                                 
Symbol
cobA
Name
(GenBank) uroporphyrinogen-III C-methyltransferase
  KO
K02302  uroporphyrin-III C-methyltransferase / precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase [EC:2.1.1.107 1.3.1.76 4.99.1.4]
Organism
ebc  Enterobacteriaceae bacterium ENNIH2
Pathway
ebc00860  Porphyrin metabolism
ebc01100  Metabolic pathways
ebc01110  Biosynthesis of secondary metabolites
ebc01120  Microbial metabolism in diverse environments
ebc01240  Biosynthesis of cofactors
Module
ebc_M00846  Siroheme biosynthesis, glutamyl-tRNA => siroheme
ebc_M00924  Cobalamin biosynthesis, anaerobic, uroporphyrinogen III => sirohydrochlorin => cobyrinate a,c-diamide
Brite
KEGG Orthology (KO) [BR:ebc00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00860 Porphyrin metabolism
    C2U52_14385 (cobA)
Enzymes [BR:ebc01000]
 1. Oxidoreductases
  1.3  Acting on the CH-CH group of donors
   1.3.1  With NAD+ or NADP+ as acceptor
    1.3.1.76  precorrin-2 dehydrogenase
     C2U52_14385 (cobA)
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.107  uroporphyrinogen-III C-methyltransferase
     C2U52_14385 (cobA)
 4. Lyases
  4.99  Other lyases
   4.99.1  Sole sub-subclass for lyases that do not belong in the other subclasses
    4.99.1.4  sirohydrochlorin ferrochelatase
     C2U52_14385 (cobA)
SSDB
Motif
Pfam: TP_methylase NAD_binding_7 CysG_dimeriser Sirohm_synth_M 2-Hacid_dh_C FAD_binding_3 Pyr_redox Shikimate_DH TrkA_N MtrH Spermine_synth
Other DBs
NCBI-ProteinID: AUV07380
LinkDB
Position
2534411..2535826
AA seq 471 aa
MDYLPLFAEVKDRPVLVVGGGDVAARKIAFLRRAGARVLVVTKHLEPSLQQLVDEQEIHL
LADTFDESQLDNVFLVIAATDDGDVNRRVFDAANARHRLVNVVDDQPLCSFIFPSIVDRS
PLLVAISSGGNAPVLARLLREKIEALLPANLGRMAEVAGRWRTRIKAFRKTTDERRRFWE
SAFRGRFASLMAAGKEQAAEQVLADELAKPGSSTGEIILVGAGPGDAGLLTLRGLQVIQQ
ADVVFYDHLVTDGVLELVRRDAELISVGKRAGSHLVAQHDTNRMLVEAAQAGKTVVRLKG
GDPFIFGRGGEELQAAAAAGIPFQVVPGVTAASGATAYAGIPLTHRDYAQSATFVTGHYK
ADSAPFDWSQLAQSRQTLAIYMGTMKAAEIGEQLIAHGREAQTPVAVISRGTRADQQVRT
GTLQQLEELAKDAPMPALLVVGEVVQLHHELAWFQHTTGPEAFDASVVNLA
NT seq 1416 nt   +upstreamnt  +downstreamnt
gtggattaccttcctttatttgctgaagtcaaagaccgccccgtgttggttgtcggtggt
ggcgacgttgccgctcgtaagattgcttttttacgtcgcgcgggggcacgcgtgctggtg
gtgacaaaacatctcgaaccctcactacaacagttggtggatgagcaagagatccacctg
ctggcggatacgttcgatgaatctcaactcgacaacgtctttctggtgattgcagcaacg
gatgacggggacgtcaaccgtcgtgtctttgacgccgcaaatgcccgccatcgtcttgtc
aacgtggtagatgaccagccgctgtgctcatttatcttcccgtcgattgttgaccgctcg
ccgttgctggtggctatctcttccggcggcaacgcaccggtactggcgcgattgctgcgt
gaaaaaattgaagcgttgttgcccgcgaacttaggccgtatggctgaggtggccgggcgc
tggcgcacgcgcattaaagcatttcgtaaaaccaccgatgaacgtcgtcgtttctgggag
agtgcctttcgtggccgctttgccagcctgatggcggcgggcaaagagcaggccgcggaa
caggtgctggctgatgaactcgcgaaaccgggcagtagcaccggcgaaatcattctggtt
ggcgcggggcccggtgatgccgggctgctaacgttgcgtggcttgcaggttatccagcag
gctgacgtggtgttttacgatcatctggtaaccgatggcgtgctggaactcgtacgccgc
gatgcggaactgatcagcgtgggtaaacgcgctggctcgcacctggttgcgcagcatgac
accaatcgcatgctggttgaggccgcgcaggcgggcaaaactgtggtgcggttgaaaggc
ggcgacccgtttatctttggtcgcggtggcgaagagttacaggcggctgcggcagcgggt
atccccttccaggtggtgccgggcgtgacggcggcatccggcgcgacggcttacgcaggc
attccgctgacacaccgcgactacgcgcaaagtgccacctttgttaccggacattacaaa
gccgacagcgcaccgtttgactggtcgcaactggcgcaaagtcgccagacgctggctatc
tatatgggtacgatgaaagcggcagaaattggcgaacaactcatcgctcacgggcgagag
gcacagacaccggtcgcggtgatttcacgcggcacacgggctgaccagcaggtcagaacc
ggcacattacaacaacttgaggaactggcgaaagatgcgccaatgcccgccctgctggtc
gtgggcgaggtggtacaactgcatcatgaactcgcctggtttcaacacacgacaggcccg
gaagcgtttgacgcctccgtggtgaatctggcttaa

DBGET integrated database retrieval system