Enterobacteriaceae bacterium ENNIH2: C2U52_15745
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Entry
C2U52_15745 CDS
T05417
Name
(GenBank) phosphoribosylformylglycinamidine synthase
KO
K01952
phosphoribosylformylglycinamidine synthase [EC:
6.3.5.3
]
Organism
ebc
Enterobacteriaceae bacterium ENNIH2
Pathway
ebc00230
Purine metabolism
ebc01100
Metabolic pathways
ebc01110
Biosynthesis of secondary metabolites
Module
ebc_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
ebc00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
C2U52_15745
Enzymes [BR:
ebc01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
C2U52_15745
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Gene cluster
GFIT
Motif
Pfam:
GATase_5
FGAR-AT_PurM_N-like
AIRS_C
FGAR-AT_N
FGAR-AT_linker
AIRS
Motif
Other DBs
NCBI-ProteinID:
AUV07618
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Position
2774654..2778541
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AA seq
1295 aa
AA seq
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MMEILRGSPALSAFRINKLLARFQAARLPVSNIYAEYVHFADVNDRLNEEELTRLQRLLK
YGPNLSSHTPTGKLLLVTPRPGTISPWSSKATDIAHNCDLGKINRLERGVAYYVEASTLT
EAQWASVAAELHDRMMETVFTAEADAARLFEHHQPAPVQSVDLLGEGRQALIDANVRLGL
ALAEDEIDYLQDAFSRLGRNPNDIELYMFAQANSEHCRHKIFNADWVIDGKQQPKSLFKM
IKNTFEKTPDYVLSAYKDNAAVMEGSEVGRFFADHENGRYDFHQEAAHILMKVETHNHPT
AISPWPGAATGSGGEIRDEGATGRGAKPKAGLVGFSVSNLRIPGFEQPWEEDFGKPERIV
SALDIMTEGPLGGAAFNNEFGRPALTGYFRTYEEKVNSHNGEELRGYHKPIMLAGGIGNI
RADHVQKGEITVGAKLIVLGGPAMNIGLGGGAASSMASGQSDADLDFASVQRDNPEMERR
CQEVIDRCWQLGDANPIQFIHDVGAGGLSNAMPELVSDGGRGGKFQLRDILSDEPGMSPL
EIWCNESQERYVLSVAADQLPLFDELCRRERAPYAVIGEAVAEQHLTMSDSHFDNQPIDL
PLDVLLGKTPKMTRDVQTRKAAGEAIDSRDISIADAVNRVLHLPAVAEKTFLVTIGDRTV
TGMVSRDQMVGPWQVPVANCAVTTASLDSYYGEAMSIGERAPVALLDFAASARLAVGESL
TNMAATQIGELNRIKLSANWMSAAGHPGEDAGLYDAVKAVGEELCPALGLTIPVGKDSMS
MKTRWQEGHEQREMTSPLSLVITAFARVEDVRRTVTPQLSTEDNALLLIDLGKGHNALGA
TALAQVYRQLGDKTADVRDVQQLKGFWNAMQALVAEGKLLAWHDRSDGGLLVTLAEMAFA
GHCGVNVDIAALGQDHLAALFNEELGGVIQVRAADREAVEALLAANGLADCVHYLGQATA
SDRFVIEAAGQAVFSESRTTLRMWWAETTWQMQRLRDNPECADEEHQAKANDSDPGLNVK
LSFDINEDIAAPYIATGARPKVAVLREQGVNSHVEMAAAFYRAGFDAIDVHMSDLLAGRT
GLEDFQALVACGGFSYGDVLGAGEGWAKSILFNNRVRDEFETFFHRPQTLALGVCNGCQM
MSNLRELVPGSELWPRFVRNHSDRFEARFSLVEVTQSPSLLLQGMVGSQMPIAVSHGEGR
VEVRDDAHLAQLESKGLVALRFVDNFGKVTQTYPANPNGSPNGITAVTNESGRVTLMMPH
PERVFRTVSNSWHPENWGEDSPWMRIFRNARKQLG
NT seq
3888 nt
NT seq
+upstream
nt +downstream
nt
atgatggaaattctgcgtggttcgcctgcactgtccgcatttcgtatcaacaaactgctg
gcgcgttttcaggcagcccggctcccggtgagcaatatttacgctgagtatgtccatttt
gccgatgtgaacgatcggctgaacgaggaagagctcacgcggctgcaacgcctgctgaaa
tatggtccgaacttgagcagccataccccaaccggaaaattacttctcgttacgccccgc
cctggcaccatctccccctggtcttctaaagcaacggatatcgcgcacaactgcgacctt
ggcaaaatcaatcgccttgagcgcggcgtggcctactatgttgaggcctcaacgctgacc
gaagcgcaatgggcaagcgtggcggctgaactgcatgaccgcatgatggagaccgtattt
accgccgaagcggatgcggcacgcctgtttgaacatcatcagcctgcgccggtgcaaagt
gtggatctgttaggtgaagggcgtcaggcgctgatcgacgctaacgtgcgtctcggcctt
gcactggcggaagacgaaattgattatctgcaggatgcgtttagccgccttggccgcaac
ccgaatgatatcgaactctacatgtttgctcaggcgaactctgaacactgccgtcataaa
atcttcaacgccgactgggtgattgacggcaaacagcagccaaagtcgctgtttaagatg
atcaaaaacaccttcgagaaaaccccggactatgtgctgtctgcctataaagacaacgcc
gcggtgatggaaggttctgaggtcgggcgtttcttcgctgaccacgagaatggtcgttat
gacttccaccaggaagcggcgcacattctgatgaaagtggaaacccacaaccacccgacg
gcgatttctccgtggccgggcgcggcaaccggttctggtggtgaaatccgtgacgaaggg
gcgaccggacgtggcgcgaagccgaaagcgggtctggtgggcttctccgtttctaacctg
cgtattccggggtttgaacagccgtgggaagaagatttcggtaagccggaacgtatcgtt
tccgcactggatatcatgaccgaaggcccacttggtggcgcggcatttaacaacgaattt
ggccgtccggcgctgaccggctacttccgtacttacgaagagaaagtgaacagccacaac
ggcgaagagctgcgtggctatcacaaaccgatcatgctggcaggcggtatcggcaacatt
cgcgccgatcacgtacaaaaaggtgagatcaccgttggcgcgaaactgatcgtcctcggc
ggcccggcgatgaacatcggtctgggcggcggcgctgcctcctccatggcctccggccag
tctgacgcggacctggattttgcttccgtgcagcgtgacaacccggaaatggagcgtcgt
tgccaggaagtgattgaccgctgctggcaactgggtgatgccaacccgatccagtttatc
catgatgtgggggcaggcggtctgtcgaacgccatgccggaactggtaagcgatggtggg
cgcggtggtaaattccagttgcgcgacatccttagcgacgaaccggggatgagcccgctg
gaaatctggtgtaacgaatcccaggagcgttatgtcctgtccgttgcggccgatcagtta
ccgctgtttgatgaactttgccgccgcgaacgcgccccgtacgcagtgattggtgaagcc
gtggcagagcaacatctgaccatgagcgacagccacttcgacaaccagccgatcgatttg
ccgctggatgtgctgctgggtaaaaccccaaaaatgacccgcgatgtgcagacacgtaaa
gcggccggtgaagccatcgattcacgtgacatttccattgcggacgcggtaaaccgtgtg
ctgcatctgcctgccgtcgccgagaaaaccttcctggtgaccatcggcgaccgtaccgtt
accggtatggtgtcgcgcgatcagatggttggcccgtggcaggtgcctgtcgctaactgt
gcggtgaccaccgccagcctggacagctactacggcgaagcgatgtccatcggtgaacgt
gcgccggtggcactgctggacttcgccgcctctgcccgtctggcggtcggtgagtccctg
accaacatggcggccacgcaaatcggtgaactcaaccgcattaagctctcggcaaactgg
atgtccgcagccggtcatccgggtgaagacgccgggttgtacgacgcggtaaaagccgtg
ggtgaggaactctgcccggcgctgggcctgaccattccggtgggtaaagactccatgtcg
atgaagacccgctggcaggaaggtcacgagcagcgcgagatgacctcgccgttgtcgctg
gtgatcaccgcttttgcccgcgtcgaagatgtgcgtcgtaccgtgacgccgcaactttct
accgaagacaacgccctgctgttgattgatttgggtaaaggccacaatgcgctgggcgca
accgcgctggcgcaggtttaccgtcaactgggcgataaaactgccgatgtgcgtgatgtc
cagcaactgaaaggtttctggaatgcgatgcaggcgctggtggcagagggcaaactgctg
gcctggcatgaccgttccgacggtggtctgctggtgacgctggccgaaatggcgtttgcc
ggtcactgcggtgtgaatgtggatatcgccgcactgggccaggatcatctggcggcgctg
tttaacgaagaactgggtggcgtcattcaggttcgtgccgcggaccgtgaagctgtagaa
gcgctgctggcggcaaacggtctggcagattgtgttcactacctggggcaggccacggcg
agtgatcggtttgttatcgaggcggcaggtcaggctgtgttcagcgaaagtcgtaccacc
ctgcgtatgtggtgggcagagaccacctggcagatgcagcgcctgcgtgacaacccggaa
tgcgctgacgaagagcatcaggcgaaagccaacgatagcgatccgggtctgaacgtgaag
ctctctttcgatattaacgaagacattgcggcaccgtatattgcgaccggcgcgcgcccg
aaagtggcggtactgcgtgagcagggcgttaactcccatgtggaaatggcggcggcgttt
taccgtgcgggctttgatgccatcgacgtccacatgagcgatctgctggccgggcgtacc
ggtctggaagatttccaggcgctggttgcctgtggcggtttctcttacggtgacgtactg
ggcgcgggtgaaggttgggcgaaatcaattctgttcaacaaccgcgtgcgcgatgagttc
gaaacctttttccaccgtccgcagacgctggcgctgggcgtatgtaacggctgccagatg
atgtctaacctgcgtgaactggtgccgggcagtgagttgtggccacgctttgtgcgtaac
cactctgaccgcttcgaagcgcgtttcagcctggtcgaagtgacccaaagtccgtcgctg
ctgctgcagggtatggtcggttcacaaatgcctatcgcggtttcccacggtgaaggccgc
gtggaagtgcgtgatgatgcccatctggctcagcttgaaagcaaaggtctggtggcgctg
cgctttgtcgataacttcggtaaagtgacccaaacctatccggctaacccgaacggttcg
ccaaacggtattaccgcggttaccaacgaaagtggtcgcgtgacgctgatgatgccgcat
ccggagcgtgtgttccgtacggtttctaactcctggcacccggaaaactggggcgaggac
agcccgtggatgcgtatcttccgcaatgcgcgtaagcagttaggttaa
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