Escherichia coli BL21(DE3): B21_02481
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Entry
B21_02481 CDS
T02096
Symbol
gabD
Name
(GenBank) succinate semialdehyde dehydrogenase, NADP[+]-dependent
KO
K00135
succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:
1.2.1.16
1.2.1.79
1.2.1.20
]
Organism
ebe
Escherichia coli BL21(DE3)
Pathway
ebe00250
Alanine, aspartate and glutamate metabolism
ebe00310
Lysine degradation
ebe00350
Tyrosine metabolism
ebe00650
Butanoate metabolism
ebe00760
Nicotinate and nicotinamide metabolism
ebe01100
Metabolic pathways
ebe01120
Microbial metabolism in diverse environments
Module
ebe_M00027
GABA (gamma-Aminobutyrate) shunt
ebe_M00956
Lysine degradation, bacteria, L-lysine => succinate
Brite
KEGG Orthology (KO) [BR:
ebe00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00650 Butanoate metabolism
B21_02481 (gabD)
09105 Amino acid metabolism
00250 Alanine, aspartate and glutamate metabolism
B21_02481 (gabD)
00310 Lysine degradation
B21_02481 (gabD)
00350 Tyrosine metabolism
B21_02481 (gabD)
09108 Metabolism of cofactors and vitamins
00760 Nicotinate and nicotinamide metabolism
B21_02481 (gabD)
Enzymes [BR:
ebe01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.1 With NAD+ or NADP+ as acceptor
1.2.1.16 succinate-semialdehyde dehydrogenase [NAD(P)+]
B21_02481 (gabD)
1.2.1.20 glutarate-semialdehyde dehydrogenase
B21_02481 (gabD)
1.2.1.79 succinate-semialdehyde dehydrogenase (NADP+)
B21_02481 (gabD)
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Motif
Pfam:
Aldedh
Motif
Other DBs
NCBI-ProteinID:
CAQ32998
UniProt:
A0A140N6Z3
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Position
2631054..2632502
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AA seq
482 aa
AA seq
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MKLNDSKLFRQQALINGEWLDANNGEVIDVTNPANGDKLGSVPKMGADETRAAIDAANRA
LPAWRALTAKERANILRNWFNLLMEHQDDLARLMTLEQGKPLAEAKGEISYAASFIEWFA
EEGKRIYGDTIPGHQADKRLIVIKQPIGVTAAITPWNFPAAMITRKAGPALAAGCTMVLK
PASQTPFSALALAELAIRAGIPAGVFNVVTGSAGAVGNELTSNPLVRKLSFTGSTEIGRQ
LMEQCAKDIKKVSLELGGNAPFIVFDDADLDKAVEGALSSKFRNAGQTCVCANRLYVQDG
VYDRFAEKLQQAVSKLHIGDGLEKGVTIGPLIDEKAVAKVEEHIADALEKGARVVCGGKA
DERGGNFFQPTILVDVPANAKVSKEETFGPLAPLFRFKDEADVIAQANDTEFGLAAYFYA
RDLSRVFRVGEALEYGIVGINTGIISNEVAPFGGIKASGLGREGSKYGIEDYLEIKYMCI
GL
NT seq
1449 nt
NT seq
+upstream
nt +downstream
nt
atgaaacttaacgacagtaaattattccgccagcaggcgttgattaacggggaatggctg
gacgccaacaatggcgaggtcatcgatgtcaccaatccggcgaacggcgacaagctgggt
agcgtacccaaaatgggcgctgatgaaacccgcgccgctatcgacgccgccaaccgcgct
ctgcccgcctggcgtgcgctcaccgccaaagaacgcgccaacattctgcgcaactggttc
aatttgttgatggagcatcaggacgatttagcgcgcctgatgaccctagaacagggcaaa
ccgctggctgaagcgaaaggcgaaattagctacgccgcctcctttattgagtggtttgct
gaagaaggcaaacgcatttatggcgacaccattcctggtcatcaggccgataagcgcctg
attgttatcaagcagccgattggcgtcaccgcagctatcacgccgtggaacttcccggcg
gcgatgattacccgcaaagccggtccggcgctggcggcaggctgcaccatggtgctgaag
cctgccagtcagacgccgttctctgcgctggcgctggcggagctggcgattcgcgcgggc
attccggctggggtatttaacgtggtcaccggttcggcgggcgcggtgggtaacgaactg
accagcaacccgctggtgcgcaagctgtcgtttaccggttcgaccgaaattggccgccag
ttaatggaacagtgcgcgaaagacatcaaaaaagtgtcgctggagctgggcggcaacgcg
ccgtttatcgtctttgacgatgccgacctcgacaaagccgtggaaggtgcgctgtcctcg
aaattccgcaacgccgggcaaacctgcgtctgcgccaaccgtttatacgtgcaggacggc
gtgtatgaccgctttgccgaaaaattgcagcaggcggtgagcaaattgcacatcggcgac
gggctggagaaaggcgtcaccatcgggccgctgatcgatgaaaaagcggtagcaaaagtg
gaagagcatattgccgatgcgctggagaaaggtgcgcgtgtggtttgcggcggtaaagcg
gatgaacgcggcggcaacttcttccagccgaccattctggtggacgttccagccaacgcc
aaagtgtcgaaagaagagacgttcggccccctcgccccactgttccgttttaaagatgaa
gccgatgtgattgcgcaagccaatgacaccgagtttggccttgccgcctatttctacgcc
cgtgatttaagccgcgtcttccgcgtgggcgaagcgctggagtacggcatcgtcggcatc
aataccggcatcatttccaatgaagtggccccgttcggcggcattaaagcctcgggtctg
ggtcgtgaaggttcgaagtatggcatcgaagattacttagaaatcaaatatatgtgcatc
ggtctttaa
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