Escherichia coli B REL606: ECB_00087
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Entry
ECB_00087 CDS
T00944
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide:D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
ebr
Escherichia coli B REL606
Pathway
ebr00300
Lysine biosynthesis
ebr00550
Peptidoglycan biosynthesis
ebr01100
Metabolic pathways
ebr01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
ebr00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
ECB_00087 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
ECB_00087 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
ECB_00087 (murF)
Enzymes [BR:
ebr01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
ECB_00087 (murF)
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
LpxD
Motif
Other DBs
NCBI-ProteinID:
ACT37780
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Position
97454..98812
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AA seq
452 aa
AA seq
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MISVTLSQLTDILNGELQGADITLDAVTTDTRKLTPGCLFVALKGERFDAHDFADQAKAG
GAGALLVSRPLDIDLPQLIVKDTRLAFGELAAWVRQQVPARVVALTGSSGKTSVKEMTAA
ILSQCGNTLYTAGNLNNDIGVPMTLLRLTPEYDYAVIELGANHQGEIAWTVSLTRPEAAL
VNNLAAAHLEGFGSLAGVAKAKGEIFSGLPENGIAIMNADNNDWLNWQSVIGSRKVWRFS
PNAANSDFTATNIHVTSHGTEFTLQTPTGSVDVLLPLPGRHNIANALAAAALSMSVGATL
DAIKAGLANLKAVPGRLFPIQLAENQLLLDDSYNANVGSMTAAVQVLAEMPGYRVLVVGD
MAELGAESEACHVQVGEAAKAAGIDRVLSVGKQSHAISTASGVGEHFADKTALITRLKSL
IAEQQVITILVKGSRSAAMEEVVRALQENGTC
NT seq
1359 nt
NT seq
+upstream
nt +downstream
nt
atgattagcgtaacccttagccaacttaccgacattctcaacggtgaactgcaaggtgca
gatatcacccttgatgctgtaaccactgatacccgaaaactgacgccgggctgcctgttt
gttgccctgaaaggcgaacgttttgatgcccacgattttgccgaccaggcgaaagctggc
ggcgcaggcgcactactggttagccgtccgctggacatcgacctgccgcagttaatcgtc
aaggatacgcgtctggcgtttggtgaactggctgcatgggttcgccagcaagttccggcg
cgcgtggttgctctgacggggtcctccggcaaaacctccgttaaagagatgacggcggcg
attttaagccagtgcggcaacacgctttatacggcaggcaatctcaacaacgacatcggt
gtaccgatgacgctgttgcgcttaacgccggaatacgattacgcagttattgaacttggc
gcgaaccatcagggcgaaatagcctggactgtgagtctgactcgcccggaagctgcgctg
gtcaacaacctggcagcggcgcatctggaaggttttggctcgcttgcgggtgtcgcgaaa
gcgaaaggtgaaatctttagcggcctgccggaaaacggtatcgccattatgaacgccgac
aacaacgactggctgaactggcagagcgtaattggctcacgcaaagtgtggcgtttctca
cccaatgccgccaacagcgatttcaccgccaccaatatccatgtgacctcgcacggtacg
gaatttaccctacaaaccccaaccggtagcgtcgatgttctgctgccgttgccggggcgt
cacaatattgcgaatgcgctggcagccgctgcgctctccatgtccgtgggcgcaacgctt
gatgctatcaaagcggggctggcaaatctgaaagctgttccaggccgtctgttccccatc
caactggcagaaaaccagttgctgctcgacgactcctacaacgccaatgtcggttcaatg
actgcagcagtccaggtactggctgaaatgccgggctaccgcgtgctggtggtgggcgat
atggcggaactgggcgctgaaagcgaagcctgccatgtacaggtgggcgaggcggcaaaa
gctgctggtattgaccgcgtgttaagcgtgggtaaacaaagccatgctatcagcaccgcc
agcggcgttggcgaacattttgctgataaaactgcgttaattacgcgtcttaaatcactg
attgctgagcaacaggtaattacgattttagttaagggttcacgtagtgccgccatggaa
gaggtagtacgcgctttacaggagaatgggacatgttag
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