Escherichia coli B REL606: ECB_02449
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Entry
ECB_02449 CDS
T00944
Symbol
purL
Name
(GenBank) phosphoribosylformylglycinamidine synthase
KO
K01952
phosphoribosylformylglycinamidine synthase [EC:
6.3.5.3
]
Organism
ebr
Escherichia coli B REL606
Pathway
ebr00230
Purine metabolism
ebr01100
Metabolic pathways
ebr01110
Biosynthesis of secondary metabolites
Module
ebr_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
ebr00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
ECB_02449 (purL)
Enzymes [BR:
ebr01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
ECB_02449 (purL)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
GATase_5
FGAR-AT_PurM_N-like
AIRS_C
FGAR-AT_N
FGAR-AT_linker
Motif
Other DBs
NCBI-ProteinID:
ACT40103
LinkDB
All DBs
Position
complement(2612373..2616260)
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AA seq
1295 aa
AA seq
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MMEILRGSPALSAFRINKLLARFQAARLPVHNIYAEYVHFADLNAPLNDDEHAQLERLLK
YGPALASHAPQGKLLLVTPRPGTISPWSSKATDIAHNCGLQQVNRLERGVAYYIEAGTLT
NEQWQQVTAELHDRMMETVFFALDDAEQLFAHHQPTPVTSVDLLGQGRQALIDANLRLGL
ALAEDEIDYLQDAFTKLGRNPNDIELYMFAQANSEHCRHKIFNADWVIDGEQQPKSLFKM
IKNTFETTPDYVLSAYKDNAAVMEGSEVGRYFADHETGRYDFHQEPAHILMKVETHNHPT
AISPWPGAATGSGGEIRDEGATGRGAKPKAGLVGFSVSNLRIPGFEQPWEEDFGKPERIV
TALDIMTEGPLGGAAFNNEFGRPALNGYFRTYEEKVNSHNGEELRGYHKPIMLAGGIGNI
RADHVQKGEINVGAKLVVLGGPAMNIGLGGGAASSMASGQSDADLDFASVQRDNPEMERR
CQEVIDRCWQLGDANPILFIHDVGAGGLSNAMPELVSDGGRGGKFELRDILSDEPGMSPL
EIWCNESQERYVLAVAADQLPLFDELCKRERAPYAVIGEATEELHLSLHDRHFDNQPIDL
PLDVLLGKTPKMTRDVQTLKAKGDALAREGITIADAVKRVLHLPTVAEKTFLVTIGDRSV
TGMVARDQMVGPWQVPVANCAVTTASLDSYYGEAMAIGERAPVALLDFAASARLAVGEAL
TNIAATQIGDIKRIKLSANWMAAAGHPGEDAGLYEAVKAVGEELCPALGLTIPVGKDSMS
MKTRWQEGNEEREMTSPLSLVISAFARVEDVRHTITPQLSTEDNALLLIDLGKGNNALGA
TALAQVYRQLGDKPADVRDVAQLKGFYDAIQALVAQRKLLAYHDRSDGGLLVTLAEMAFA
GHCGINADIASLGDDRLAALFNEELGAVIQVRAADREAVESVLAQHGLADCVHYVGQAVS
GDRFVITANGQTVFSESRTTLRVWWAETTWQMQRLRDNPECADQEHQAKSNDADPGLNVK
LSFDINEDVAAPYIATGARPKVAVLREQGVNSHVEMAAAFHRAGFDAIDVHMSDLLTGRT
GLEDFHALVACGGFSYGDVLGAGEGWAKSILFNDRVRDEFATFFHRPQTLALGVCNGCQM
MSNLRELIPGSELWPRFVRNTSDRFEARFSLVEVTQSPSLLLQGMVGSQMPIAVSHGEGR
VEVRDAAHLAALESKGLVALRYVDNFGKVTETYPANPNGSPNGITSVTTESGRVTIMMPH
PERVFRTVSNSWHPENWGEDGPWMRIFRNARKQLG
NT seq
3888 nt
NT seq
+upstream
nt +downstream
nt
atgatggaaattctgcgtggttcgcctgcactgtcggcattccgaatcaacaaactgctg
gcacgttttcaggctgccaggctcccggttcacaatatttacgccgagtatgtccatttt
gctgacctcaatgcgccgttaaacgatgatgagcacgcacaacttgaacgcctgctgaaa
tatggtccggcactcgccagccacgccccgcaaggcaaactcctgctggtgaccccgcgt
cctggcaccatctctccctggtcttcgaaagcgaccgatattgcccataactgcgggcta
caacaggtaaaccgccttgagcgcggcgttgcttactatatagaagccggtacgctgacc
aatgaacaatggcagcaggttaccgctgaactgcacgaccgcatgatggaaacggtcttt
tttgctttagatgatgcagagcagttgtttgcccaccatcaaccgactccggtcacaagc
gttgatttgctggggcagggccgtcaggcgctaatcgacgctaacctgcgtcttggcctg
gcactggcggaagatgaaattgactatctgcaggatgctttcacaaagcttggtcgtaac
ccgaacgacatcgagctgtatatgttcgcccaggcgaactccgagcactgtcgccacaag
atttttaacgccgattgggttatcgacggtgagcaacagccgaaatcgctgtttaagatg
atcaaaaacaccttcgaaaccacgccagattacgttctctctgcttataaagataacgcc
gccgtaatggaaggttctgaagtgggccgctactttgctgaccacgaaacgggccgctac
gatttccatcaggaaccggcgcatattctgatgaaagtcgaaactcacaaccacccgacg
gcgatttctccgtggccgggcgcggcgaccggttccggcggtgaaatccgcgatgaaggt
gccaccgggcgcggcgcgaagccgaaagcgggtttggttggtttctccgtttccaacctg
cgaattcctggcttcgaacagccgtgggaagaagatttcggtaagcctgagcgcattgtc
accgcgctggacatcatgaccgaaggcccgctgggcggcgcggcgtttaacaacgaattt
ggtcgtccggcactgaatggctacttccgtacttatgaagaaaaagtgaacagccacaac
ggcgaagagctgcgcggttatcacaaaccgatcatgctggcgggcgggatcggcaacatt
cgcgccgatcacgtacaaaaaggcgagatcaacgtcggtgcgaagctggtcgttctcggc
ggcccggcaatgaacatcggtcttggcggcggagcggcgtcttccatggcgtcaggtcag
tctgatgccgacctcgactttgcttccgtacagcgcgacaacccggagatggagcgtcgt
tgccaggaagtgatcgaccgttgctggcagcttggtgatgctaacccaattctgtttatc
cacgacgtcggtgcgggcggtctttctaacgcgatgccggagctggtgagcgacggcgga
cgcggcggtaaatttgaactgcgcgatattctaagcgacgaaccgggcatgagcccgctg
gaaatctggtgtaacgaatcccaggaacgctacgtgctggcggttgctgccgatcaatta
ccgctgtttgacgaactgtgtaagcgtgaacgcgcaccctacgcggtgattggtgaagcg
accgaagaactgcatctttctctgcacgatcgtcattttgataatcagccgatcgatctg
ccgctggacgtcctgcttggtaaaacgccgaagatgacccgcgatgtacaaacgctgaaa
gcgaaaggcgacgcgctggcccgtgaagggatcaccattgcagatgcggtgaaacgtgtg
ctgcatctgccgactgtggcggaaaaaaccttcctggtgaccattggcgaccgcagcgta
accggcatggtagcgcgcgatcagatggtggggccgtggcaggtgccggtcgctaactgc
gcggtcactaccgccagcctcgacagctactacggtgaagcgatggcgattggcgagcgt
gcgccggttgcgctgctggatttcgccgcctctgcccgtctggcggtcggtgaagcgtta
accaatattgccgcaacacagattggtgatatcaaacgcattaaactttccgccaactgg
atggcggcggcaggccaccctggtgaagatgcgggcctgtatgaagccgttaaagccgtg
ggcgaagagctttgtccggcgctgggcctgacgatcccggtgggtaaagactctatgtcg
atgaaaacccgctggcaggaaggtaacgaagagcgcgaaatgacgtcgccgctgtcgctg
gtgatttctgcatttgcccgcgtggaagatgtgcgtcacaccatcacgccacagctttct
accgaagataacgcactgctgctgattgatttgggcaaaggcaataacgcgctgggcgca
acggcgctggcgcaggtttatcgtcagcttggcgacaaaccggcagatgtacgcgacgtc
gcgcaactgaaaggcttctatgacgcgattcaggcgctggttgcacagcgtaagctgctc
gcataccacgaccgctctgatggcggcctgctggtaacgctggcggaaatggcctttgct
ggtcattgcggcattaacgcggatattgcctctctgggcgacgatcgcctggcggcgttg
tttaacgaagaactgggtgcggtgattcaggttcgtgccgctgaccgtgaagcggttgag
tccgtactggcacagcatgggcttgctgattgtgtccattatgtagggcaggcggtttcc
ggtgaccgttttgtgattaccgccaacgggcagactgtattcagcgaaagccgcaccacg
ttgcgtgtctggtgggcagaaactacctggcagatgcagcgcctgcgtgacaacccggag
tgtgctgaccaggagcaccaggcgaaatctaacgatgccgatcctggcctgaatgtaaaa
ctgtcgttcgatatcaacgaagatgtggcagcaccgtatattgccactggcgcacgtccg
aaagttgccgtactgcgtgagcagggcgtgaactcgcatgttgaaatggcggcagctttc
caccgtgcaggctttgatgctatcgacgtgcatatgagtgacctgctgaccggacgcacg
ggcctggaagatttccacgccctggtcgcgtgcggtggtttctcctacggtgatgtgctg
ggtgccggtgaaggttgggcgaagtcaatcctgttcaatgaccgtgtacgcgatgagttt
gcaaccttcttccaccgtccgcaaacgctggcgctgggggtatgtaacggttgccagatg
atgtctaacctgcgcgaactgatcccaggtagtgagttgtggccacgttttgtgcgcaat
acctccgatcgctttgaagcgcgtttcagcctggttgaagtaacccaaagcccgtctctg
ctgttgcaggggatggtgggctcgcaaatgccgattgctgtctctcatggtgaagggcgc
gtggaagtgcgtgatgcggcgcatctggcggcactggaaagcaaagggctggtggcactg
cgctatgttgataacttcggcaaagtcactgaaacctacccggctaacccgaacggttca
ccgaacggtattacgtcggttacgactgaaagtggtcgagtcaccattatgatgccgcac
ccggaacgtgttttccgtactgtcagcaactcctggcatccggaaaactggggcgaggat
ggcccatggatgcgcattttccgcaatgcgcgtaagcagttggggtaa
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