Enterobacteriaceae bacterium S05: CUC76_11185
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Entry
CUC76_11185 CDS
T05725
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
ebu
Enterobacteriaceae bacterium S05
Pathway
ebu00300
Lysine biosynthesis
ebu00550
Peptidoglycan biosynthesis
ebu01100
Metabolic pathways
ebu01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
ebu00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
CUC76_11185
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
CUC76_11185
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
CUC76_11185
Enzymes [BR:
ebu01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
CUC76_11185
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Paralog
Gene cluster
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
YAcAr
LpxD
Motif
Other DBs
NCBI-ProteinID:
AWB62113
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Position
complement(2247112..2248470)
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AA seq
452 aa
AA seq
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MIRFTLSQLAAIAHGERQGSDIAIDEVTTDTRKVTAGCLFVALKGERFDAHDFAEQAKAA
GAGALLVSRPLACDLPQVIVKDTRQAFGELAAWVRQQVPTRVVALTGSSGKTSVKEMTAA
ILSQCGNTLYTAGNLNNDIGVPMTLLRLTKEHQYAVIELGANHQGEIAWTVSLTRPEAAL
VNNLAAAHLEGFGSLAGVAKAKGEIYTGLPENGIAILNADNNDWLNWQAVIGDRKVWRFS
PNAANSDFTATNVQITSHGTEFTLQTPTGNVDVLLPLPGRHNIANALAATSLAMAVGADL
AAVKAGLAQLQAVPGRLFPIRLTESQLLLDDSYNANVGSMTAAVQVLSEMPGFRTMVVGD
MAELGAESAACHREVGEAAKAAGLDRVLSVGALSADISHASGVGEHFNDKAAVVARLREL
LAEHNIMTILVKGSRSAAMEEVVRALQETGTC
NT seq
1359 nt
NT seq
+upstream
nt +downstream
nt
atgattcgctttacgttaagccagctcgccgcgatcgcccatggcgaacggcagggtagc
gatatcgctatcgacgaggtgaccaccgacacccgtaaagtcacagcgggctgcctgttt
gtggcgctaaaaggcgagcgtttcgacgcccatgattttgccgaacaggcaaaagcggca
ggcgccggcgcgctgctggtgagccgtccgctggcctgcgatctcccgcaggtgatcgtg
aaagatacccggcaggctttcggcgagttagccgcctgggtccgtcagcaggtgccgacc
cgcgtcgtcgccctaaccggctcgtcaggtaaaacctcggtcaaagagatgaccgcggcg
atcctcagccagtgcggcaacacgctgtataccgccggcaacctgaacaacgatatcggc
gtaccgatgactctgctgcgtctgaccaaagaacatcagtacgcggtgattgagctcggc
gccaaccaccagggcgaaatcgcctggaccgtcagcctgacgcgtcctgaagcggcgctg
gtcaacaaccttgccgccgcgcaccttgaaggtttcggctcgctggcgggcgtggcgaag
gcgaagggcgaaatctataccggtctgccggaaaacggcatcgccattctcaatgccgac
aacaacgactggctgaactggcaggcagtgattggcgatcgcaaagtgtggcgcttctca
ccgaatgcggccaacagcgatttcactgcgactaacgtgcagatcaccagccacggcacc
gaatttacgctgcagactccaaccggtaacgttgatgtactgctgccgctgccgggacgc
cacaacatcgctaacgcgctggcggcgacctcgctggcgatggcggtaggcgccgatctg
gcggcggtgaaagccggtctggcgcagctgcaggccgttccgggacgtctgttcccgatc
cgcctgaccgagagccagctgctgctggatgactcctacaacgctaacgtcggttcgatg
accgcggcggtgcaggtcctgtcagagatgcccggcttccggacgatggtggtcggcgat
atggccgaacttggcgcggaaagcgcggcttgccaccgtgaagtcggcgaagcggcgaaa
gcggcaggcctggatcgcgttctcagcgtcggcgccttgagcgcggatatcagccacgcc
agcggcgtgggcgaacattttaacgataaagccgccgtggtggctcgcctgcgcgagctg
ctggcggagcataatataatgaccattttagtgaagggttcacgtagtgccgccatggaa
gaggtagtacgcgcattacaggagactgggacatgttag
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