Escherichia coli K-12 BW2952: BWG_0068
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Entry
BWG_0068 CDS
T00913
Symbol
leuC
Name
(GenBank) 3-isopropylmalate isomerase subunit, dehydratase component
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
ebw
Escherichia coli K-12 BW2952
Pathway
ebw00290
Valine, leucine and isoleucine biosynthesis
ebw00660
C5-Branched dibasic acid metabolism
ebw01100
Metabolic pathways
ebw01110
Biosynthesis of secondary metabolites
ebw01210
2-Oxocarboxylic acid metabolism
ebw01230
Biosynthesis of amino acids
Module
ebw_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
ebw00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
BWG_0068 (leuC)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
BWG_0068 (leuC)
Enzymes [BR:
ebw01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
BWG_0068 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
BWG_0068 (leuC)
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Motif
Pfam:
Aconitase
Spo0M
Motif
Other DBs
NCBI-ProteinID:
ACR61816
UniProt:
C4ZPZ5
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Position
complement(79463..80863)
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AA seq
466 aa
AA seq
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MAKTLYEKLFDAHVVYEAENETPLLYIDRHLVHEVTSPQAFDGLRAHGRPVRQPGKTFAT
MDHNVSTQTKDINACGEMARIQMQELIKNCKEFGVELYDLNHPYQGIVHVMGPEQGVTLP
GMTIVCGDSHTATHGAFGALAFGIGTSEVEHVLATQTLKQGRAKTMKIEVQGKAAPGITA
KDIVLAIIGKTGSAGGTGHVVEFCGEAIRDLSMEGRMTLCNMAIEMGAKAGLVAPDETTF
NYVKGRLHAPKGKDFDDAVAYWKTLQTDEGATFDTVVTLQAEEISPQVTWGTNPGQVISV
NDNIPDPASFADPVERASAEKALAYMGLKPGIPLTEVAIDKVFIGSCTNSRIEDLRAAAE
IAKGRKVAPGVQALVVPGSGPVKAQAEAEGLDKIFIEAGFEWRLPGCSMCLAMNNDRLNP
GERCASTSNRNFEGRQGRGGRTHLVSPAMAAAAAVTGHFADIRNIK
NT seq
1401 nt
NT seq
+upstream
nt +downstream
nt
atggctaagacgttatacgaaaaattgttcgacgctcacgttgtgtacgaagccgaaaac
gaaaccccactgttatatatcgaccgccacctggtgcatgaagtgacctcaccgcaggcg
ttcgatggtctgcgcgcccacggtcgcccggtacgtcagccgggcaaaaccttcgctacc
atggatcacaacgtctctacccagaccaaagacattaatgcctgcggtgaaatggcgcgt
atccagatgcaggaactgatcaaaaactgcaaagaatttggcgtcgaactgtatgacctg
aatcacccgtatcaggggatcgtccacgtaatgggcccggaacagggcgtcaccttgccg
gggatgaccattgtctgcggcgactcgcataccgccacccacggcgcgtttggcgcactg
gcctttggtatcggcacttccgaagttgaacacgtactggcaacgcaaaccctgaaacag
ggccgcgcaaaaaccatgaaaattgaagtccagggcaaagccgcgccgggcattaccgca
aaagatatcgtgctggcaattatcggtaaaaccggtagcgcaggcggcaccgggcatgtg
gtggagttttgcggcgaagcaatccgtgatttaagcatggaaggtcgtatgaccctgtgc
aatatggcaatcgaaatgggcgcaaaagccggtctggttgcaccggacgaaaccaccttt
aactatgtcaaaggccgtctgcatgcgccgaaaggcaaagatttcgacgacgccgttgcc
tactggaaaaccctgcaaaccgacgaaggcgcaactttcgataccgttgtcactctgcaa
gcagaagaaatttcaccgcaggtcacctggggcaccaatcccggccaggtgatttccgtg
aacgacaatattcccgatccggcttcgtttgccgatccggttgaacgcgcgtcggcagaa
aaagcgctggcctatatggggctgaaaccgggtattccgctgaccgaagtggctatcgac
aaagtgtttatcggttcctgtaccaactcgcgcattgaagatttacgcgcggcagcggag
atcgccaaagggcgaaaagtcgcgccaggcgtgcaggcactggtggttcccggctctggc
ccggtaaaagcccaggcggaagcggaaggtctggataaaatctttattgaagccggtttt
gaatggcgcttgcctggctgctcaatgtgtctggcgatgaacaacgaccgtctgaatccg
ggcgaacgttgtgcctccaccagcaaccgtaactttgaaggccgccaggggcgcggcggg
cgcacgcatctggtcagcccggcaatggctgccgctgctgctgtgaccggacatttcgcc
gacattcgcaacattaaataa
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