KEGG   Escherichia coli K-12 BW2952: BWG_0069
Entry
BWG_0069          CDS       T00913                                 
Symbol
leuB
Name
(GenBank) 3-isopropylmalate dehydrogenase
  KO
K00052  3-isopropylmalate dehydrogenase [EC:1.1.1.85]
Organism
ebw  Escherichia coli K-12 BW2952
Pathway
ebw00290  Valine, leucine and isoleucine biosynthesis
ebw00660  C5-Branched dibasic acid metabolism
ebw01100  Metabolic pathways
ebw01110  Biosynthesis of secondary metabolites
ebw01210  2-Oxocarboxylic acid metabolism
ebw01230  Biosynthesis of amino acids
Module
ebw_M00432  Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:ebw00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00660 C5-Branched dibasic acid metabolism
    BWG_0069 (leuB)
  09105 Amino acid metabolism
   00290 Valine, leucine and isoleucine biosynthesis
    BWG_0069 (leuB)
Enzymes [BR:ebw01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.85  3-isopropylmalate dehydrogenase
     BWG_0069 (leuB)
SSDB
Motif
Pfam: Iso_dh DUF6259
Other DBs
NCBI-ProteinID: ACR61814
LinkDB
Position
complement(80866..81957)
AA seq 363 aa
MSKNYHIAVLPGDGIGPEVMTQALKVLDAVRNRFAMRITTSHYDVGGAAIDNHGQPLPPA
TVEGCEQADAVLFGSVGGPKWEHLPPDQQPERGALLPLRKHFKLFSNLRPAKLYQGLEAF
CPLRADIAANGFDILCVRELTGGIYFGQPKGREGSGQYEKAFDTEVYHRFEIERIARIAF
ESARKRRHKVTSIDKANVLQSSILWREIVNEIATEYPDVELAHMYIDNATMQLIKDPSQF
DVLLCSNLFGDILSDECAMITGSMGMLPSASLNEQGFGLYEPAGGSAPDIAGKNIANPIA
QILSLALLLRYSLDADDAACAIERAINRALEEGIRTGDLARGAAAVSTDEMGDIIARYVA
EGV
NT seq 1092 nt   +upstreamnt  +downstreamnt
atgtcgaagaattaccatattgccgtattgccgggggacggtattggtccggaagtgatg
acccaggcgctgaaagtgctggatgccgtgcgcaaccgctttgcgatgcgcatcaccacc
agccattacgatgtaggcggcgcagccattgataaccacgggcaaccactgccgcctgcg
acggttgaaggttgtgagcaagccgatgccgtgctgtttggctcggtaggcggcccgaag
tgggaacatttaccaccagaccagcaaccagaacgcggcgcgctgctgcctctgcgtaag
cacttcaaattattcagcaacctgcgcccggcaaaactgtatcaggggctggaagcattc
tgtccgctgcgtgcagacattgccgcaaacggcttcgacatcctgtgtgtgcgcgaactg
accggcggcatctatttcggtcagccaaaaggccgcgaaggtagcggacaatatgaaaaa
gcctttgataccgaggtgtatcaccgttttgagatcgaacgtatcgcccgcatcgcgttt
gaatctgctcgcaagcgtcgccacaaagtgacgtcgatcgataaagccaacgtgctgcaa
tcctctattttatggcgggagatcgttaacgagatcgccacggaatacccggatgtcgaa
ctggcgcatatgtacatcgacaacgccaccatgcagctgattaaagatccatcacagttt
gacgttctgctgtgctccaacctgtttggcgacattctgtctgacgagtgcgcaatgatc
actggctcgatggggatgttgccttccgccagcctgaacgagcaaggttttggactgtat
gaaccggcgggcggctcggcaccagatatcgcaggcaaaaacatcgccaacccgattgca
caaatcctttcgctggcactgctgctgcgttacagcctggatgccgatgatgcggcttgc
gccattgaacgcgccattaaccgcgcattagaagaaggcattcgcaccggggatttagcc
cgtggcgctgccgccgttagtaccgatgaaatgggcgatatcattgcccgctatgtagca
gaaggggtgtaa

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