| Entry |
|
|---|
| Name |
2-methyl-1-pyrroline reductase;
(R)-imine reductase (ambiguous)
|
|---|
| Class |
Oxidoreductases;
Acting on the CH-NH group of donors;
With NAD+ or NADP+ as acceptor
|
|---|
| Sysname |
(R)-2-methylpyrrolidine:NADP+ 2-oxidoreductase
|
|---|
| Reaction(IUBMB) |
(R)-2-methylpyrrolidine + NADP+ = 2-methyl-1-pyrroline + NADPH + H+ [RN: R10730]
|
|---|
| Reaction(KEGG) |
|
|---|
| Substrate |
|
|---|
| Product |
|
|---|
| Comment |
The enzyme from the bacterium Streptomyces sp. GF3587 is highly specific for its substrate and forms only the (R) isomer.
|
|---|
| History |
EC 1.5.1.48 created 2014
|
|---|
| Orthology |
| K19809 | 2-methyl-1-pyrroline reductase |
|
|---|
| Genes |
|
|---|
| Reference |
|
|---|
| Authors |
Mitsukura K, Suzuki M, Shinoda S, Kuramoto T, Yoshida T, Nagasawa T |
|---|
| Title |
Purification and characterization of a novel (R)-imine reductase from Streptomyces sp. GF3587. |
|---|
| Journal |
|
|---|
| Sequence |
|
|---|
| Other DBs |
| ExplorEnz - The Enzyme Database: | 1.5.1.48 |
| ExPASy - ENZYME nomenclature database: | 1.5.1.48 |
|
|---|
| LinkDB |
|
|---|
