Pectobacterium atrosepticum SCRI1043: ECA3891
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Entry
ECA3891 CDS
T00186
Symbol
thrA
Name
(GenBank) bifunctional aspartokinase/homoserine dehydrogenase I
KO
K12524
bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:
2.7.2.4
1.1.1.3
]
Organism
eca
Pectobacterium atrosepticum SCRI1043
Pathway
eca00260
Glycine, serine and threonine metabolism
eca00261
Monobactam biosynthesis
eca00270
Cysteine and methionine metabolism
eca00300
Lysine biosynthesis
eca01100
Metabolic pathways
eca01110
Biosynthesis of secondary metabolites
eca01120
Microbial metabolism in diverse environments
eca01230
Biosynthesis of amino acids
Module
eca_M00016
Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
eca_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
eca_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:
eca00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
ECA3891 (thrA)
00270 Cysteine and methionine metabolism
ECA3891 (thrA)
00300 Lysine biosynthesis
ECA3891 (thrA)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
ECA3891 (thrA)
Enzymes [BR:
eca01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
ECA3891 (thrA)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
ECA3891 (thrA)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
Homoserine_dh
AA_kinase
ACT_9
NAD_binding_3
ACT_7
ACT
Motif
Other DBs
NCBI-ProteinID:
CAG76789
UniProt:
Q6D0A8
LinkDB
All DBs
Position
complement(4354763..4357222)
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AA seq
819 aa
AA seq
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MRVLKFGGTSVANAERFARVADIIENNARQGQVATVLSAPAKITNHLVAMIEKTVAGQDI
LPHLNDAETIFSSLLQGLAASQPGFEHARLKAFVEQEFAQLKHVLHGIALLGQCPDSVNA
AIICRGEKLSIAIMEAVFQARGYGVSVINPVEKLLAQGHYLESTVDITESTRRIAESAIP
KDHVILMAGFTAGNDKGELVVLGRNGSDYSAAVLAACLRADCCEIWTDVDGVYTCDPRQV
PDARLLKSMSYQEAMELSYFGAKVLHPRTIAPIAQFQIPCLIKNTENPQAPGTLIGMDST
DTQYPVKGITNLNNMAMVNVSGPGMKGMVGMAARVFAAMSRAGISVVLITQSSSEYSISF
CVSQNELARARKTLEDEFYLELKEGVLEPLDVMERLAIISVVGDGMRTLRGLSARLFSAL
ATANINIVAIAQGSSERSISVVVNNDVATTGVRVAHQMLFNTDQVIDVFVIGVGGVGGAL
LEQIHRQQPWLKDKHIDLRVCGIANSKAMLTNINGVSMDTWREDLAKAREPFNLGRLIRL
VKEYHLLNPVIVDCTSNQAVADQYVDFLADGFHVVTPNKKANTGSMNYYHQLRSAASKSR
RRFLYDTNVGAGLPVIENLQNLLNAGDELIRFTGILSGSLSFIFGKLDEGMSLSEATTQA
KEKGYTEPDPRDDLSGMDVARKLLILAREAGYQLELGDIEVESVLPISFDASGDVASFMQ
RLPAADDEFASRVAQARDEGKVLRYVGVIEEGRCKVKISAVGGNDPLFKVKDGENALAFY
SRYYQPLPLVLRGYGAGNDVTAAGVFADLLRTLSWKLGA
NT seq
2460 nt
NT seq
+upstream
nt +downstream
nt
atgcgagtgttgaaatttggcgggacttcagtagcgaatgcggagcgctttgcccgcgtt
gccgacattatcgaaaataacgcgcgccagggacaggtcgctaccgtattgtccgcgccg
gcgaaaattaccaaccatctggttgccatgattgagaaaaccgtcgccggacaagatatc
ctgcctcatttaaacgacgccgaaactatcttctcttcgctgctgcaaggtcttgctgca
tcccagccgggttttgaacacgcccgcctgaaggcattcgtggaacaggaattcgcacag
ctgaaacacgtcttgcatggtatcgctctgctggggcagtgtcctgacagcgtgaatgcc
gcgatcatctgccgaggggaaaaactgtctattgccatcatggaagcggtctttcaggcg
cgcggctatggggtatccgtcatcaatccggtcgaaaaactgctagcgcagggacattat
ctcgaatctaccgtcgatatcactgagtcgactcgccgtatcgctgaaagcgcgatcccg
aaagatcatgtgatcctgatggcaggctttactgctggcaacgacaaaggcgagctggtg
gtgctgggccgcaacggttcagactattccgctgcggtgctggctgcgtgcctgcgtgcg
gactgttgtgagatctggaccgatgttgacggcgtttatacttgcgatcctcgtcaggtg
ccggatgcccgattattgaaatcaatgtcctatcaggaggcgatggagctgtcctatttc
ggcgccaaagttctccaccctcgcaccattgctcctatcgcccagttccagattccctgt
ctcatcaaaaacactgaaaatcctcaggctcccggtacgctcatcggcatggacagtacc
gatacacagtatccggtgaagggcattaccaacctgaacaacatggcgatggttaacgta
tccggccccggcatgaaaggtatggtcggcatggcagcgcgcgtgtttgccgcgatgtcg
cgtgcgggtatctctgtggtgctgatcacgcagtcatcttctgaatacagcatcagcttc
tgcgtatcgcagaacgagctggcgcgtgccagaaaaacgctggaagacgagttctatctg
gaactgaaagaaggcgtgctggagccgctggatgtgatggaacgtctggcgatcatctct
gtggtgggcgatggcatgcgcacgttgcgcggtctgtctgctcgtctgttctctgcgctg
gcgacggcaaacatcaatatcgtggctatcgcacagggctcgtccgagcgctctatctct
gtcgtagtcaacaatgatgtcgccacgactggcgtgcgcgttgcacaccagatgctgttt
aacaccgatcaggtgatcgacgtgtttgttatcggcgtcggcggcgtgggtggtgcactg
ctggagcaaattcaccgccagcagccgtggttgaaagacaagcatatcgacctgcgtgtg
tgtgggatcgccaattctaaagccatgctgaccaacattaacggcgtttcgatggacacc
tggcgtgaagatctggcaaaagctcgtgagccgttcaatctgggccgtctgattcgtctg
gttaaagagtatcacctactgaacccagtgattgtcgattgcacctcgaatcaggctgtt
gccgatcagtatgtggatttcctggccgacggcttccacgtggtgacgccaaacaagaaa
gccaacaccgggtcgatgaattattatcatcaactgcgtagcgccgcatcgaaatcccgt
cgtcgtttcctgtatgacaccaacgtcggtgcaggtctgccggtgatcgagaacctgcaa
aatctgctgaatgcgggtgatgagctgattcgctttaccggtattctctctggctcgctg
tcctttattttcggtaaactcgatgaaggcatgtcactgtcggaagcgacgacgcaggcg
aaagaaaaaggctataccgaacccgatccacgtgacgatctgtctggtatggacgtggcg
cgtaagctgctgattctggcgcgtgaagcgggttatcaattggagctgggtgatattgag
gtggagtccgttctgcctatcagtttcgatgcctccggcgatgtcgccagctttatgcag
cgcctgccggcggcagacgatgagtttgccagccgtgttgcacaagcgcgtgatgaaggt
aaagtattgcgctatgtcggcgtcattgaagaaggtcgctgtaaggtcaaaatcagtgcg
gttggcggtaacgatccactgtttaaagtcaaagatggtgagaatgcgctggcgttctac
agccgttattatcagccactgccgcttgtattgcgcgggtatggcgcgggtaacgatgtt
accgctgctggtgtgttcgccgatctgctgcgcaccttgtcatggaagttgggagcataa
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