Equus caballus (horse): 100034056
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Entry
100034056 CDS
T01058
Symbol
ROCK1
Name
(RefSeq) rho-associated protein kinase 1
KO
K04514
Rho-associated protein kinase 1 [EC:
2.7.11.39
]
Organism
ecb
Equus caballus (horse)
Pathway
ecb04022
cGMP-PKG signaling pathway
ecb04024
cAMP signaling pathway
ecb04062
Chemokine signaling pathway
ecb04071
Sphingolipid signaling pathway
ecb04270
Vascular smooth muscle contraction
ecb04350
TGF-beta signaling pathway
ecb04360
Axon guidance
ecb04510
Focal adhesion
ecb04520
Adherens junction
ecb04530
Tight junction
ecb04611
Platelet activation
ecb04670
Leukocyte transendothelial migration
ecb04810
Regulation of actin cytoskeleton
ecb04921
Oxytocin signaling pathway
ecb05135
Yersinia infection
ecb05163
Human cytomegalovirus infection
ecb05200
Pathways in cancer
ecb05205
Proteoglycans in cancer
ecb05206
MicroRNAs in cancer
Brite
KEGG Orthology (KO) [BR:
ecb00001
]
09130 Environmental Information Processing
09132 Signal transduction
04350 TGF-beta signaling pathway
100034056 (ROCK1)
04071 Sphingolipid signaling pathway
100034056 (ROCK1)
04024 cAMP signaling pathway
100034056 (ROCK1)
04022 cGMP-PKG signaling pathway
100034056 (ROCK1)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
100034056 (ROCK1)
04520 Adherens junction
100034056 (ROCK1)
04530 Tight junction
100034056 (ROCK1)
09142 Cell motility
04810 Regulation of actin cytoskeleton
100034056 (ROCK1)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
100034056 (ROCK1)
04670 Leukocyte transendothelial migration
100034056 (ROCK1)
04062 Chemokine signaling pathway
100034056 (ROCK1)
09152 Endocrine system
04921 Oxytocin signaling pathway
100034056 (ROCK1)
09153 Circulatory system
04270 Vascular smooth muscle contraction
100034056 (ROCK1)
09158 Development and regeneration
04360 Axon guidance
100034056 (ROCK1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
100034056 (ROCK1)
05206 MicroRNAs in cancer
100034056 (ROCK1)
05205 Proteoglycans in cancer
100034056 (ROCK1)
09172 Infectious disease: viral
05163 Human cytomegalovirus infection
100034056 (ROCK1)
09171 Infectious disease: bacterial
05135 Yersinia infection
100034056 (ROCK1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
ecb01001
]
100034056 (ROCK1)
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
ecb03036
]
100034056 (ROCK1)
Enzymes [BR:
ecb01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.39 ROCK-subfamily protein kinase
100034056 (ROCK1)
Protein kinases [BR:
ecb01001
]
Serine/threonine kinases: AGC group
DMPK family [OT]
100034056 (ROCK1)
Chromosome and associated proteins [BR:
ecb03036
]
Eukaryotic type
Centrosome formation proteins
Kinases and associated factors
100034056 (ROCK1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
Rho_Binding
PH_MRCK
PH
C1_1
Pkinase_C
CC_Bre1
APH
Motif
Other DBs
NCBI-GeneID:
100034056
NCBI-ProteinID:
NP_001157457
Ensembl:
ENSECAG00000021002
VGNC:
22496
UniProt:
F6XUQ9
LinkDB
All DBs
Position
8:43568957..43729788
Genome browser
AA seq
1354 aa
AA seq
DB search
MSTGDSFETRFEKIDNLLRDPKSEVNSDCLLDGLDALVYDLDFPALRKNKNIDNFLSRYK
DTINKIRDLRMKAEDYEVVKVIGRGAFGEVQLVRHKSTRKVYAMKLLSKFEMIKRSDSAF
FWEERDIMAFANSPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSNYDVPEKWARFYTA
EVVLALDAIHSMGFIHRDVKPDNMLLDKSGHLKLADFGTCMKMNKEGMVRCDTAVGTPDY
ISPEVLKSQGGDGYYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMNHKNSLTFP
DDNDISKEAKNLICAFLTDREVRLGRNGVEEIKRHLFFKNDQWAWETLRDTVAPVVPDLS
SDIDTSNFDDLEEDKGDEETFPIPKAFVGNQLPFVGFTYYSNRRYLSSTNPNDNRTSSNV
DKSLQENLQKTIYKLEEQLHNEMQLKDEMEQKCRTSNIKLDKIMKELDEEGNQRRNLEST
VSQIEKEKMLLQHRINEYQRKAEQENEKRRNVENEVSTLKDQLEDLKKVSQNSQLANEKV
AQLQKQLEEANDLLRTESDTAVRLRKSHTEMSKSVSQLESLNRELQERNRILENSKSQTD
KDYYQLQAALEAERRDRGHDSEMIGDLQARITSLQEEVKHLKHNLERVEGERKEAQDMLT
HSEKEKNNLEIDLNYKLKSLQQRLEQEINEHKVTKARLTDKHQSIEEAKSVAMCEMEKKL
KEEREAREKAENRVVQIEKQCSMLDVDLKQSQQKLEHLTENKERMEDEVKNLTLQLEQES
NKRLLLQNELKTQAFEADNLKGLEKQMKQEINTLLEAKRLLEFELGQLTKQYRGNEGQMR
ELQDQLEAEQYFSTLYKTQVKELKEEIEEKNRENLKKIQELQNEKETLATQLDLAETKAE
SEQLARGLLEEQYFELTQESKKAASRNRQEITDKDHTVSRLEETNSMLTKDIELLRKENE
ELTDKMRKTEEEYKLKKEEEISNLKAAYEKNINTERTLKTQAVNKLAEIMNRKDFKIDRK
KANTQDLRKKEKENRKLQLELNQEREKFNQMVVKHQKELNDMQAQLLEECTHRNELQMQL
ASKESDIEQLRAKLLDLSDSTSVASFPSADETDGNLPESRIEGWLSIPNRGNIKRYGWKK
QYVVVSSKKILFYNDEQDKEQSNPSMVLDIDKLFHVRPVTQGDVYRAETEEIPKIFQILY
ANEGECRKDVDMEPVQQAEKTNFQNHKGHEFIPTLYHFPANCEACAKPLWHVFKPPPALE
CRRCHVKCHRDHLDKKEDLISPCKVSYDVTSARDMLLLACSQDEQKKWVTHLVKKIPKNP
PSGFVRASPRTLSTRSTANQSFRKVVKNTSGKAS
NT seq
4065 nt
NT seq
+upstream
nt +downstream
nt
atgtcgactggggacagttttgagactcggtttgaaaaaatagacaacctgctgcgggat
cccaaatcggaagtgaattcggattgtttgctggatggattggatgctttggtatatgat
ttggattttcctgccttaagaaaaaacaaaaatattgacaactttttaagcagatataaa
gacacaataaataaaattagagatctgcgaatgaaagctgaagattatgaagtagtgaag
gtgattggtagaggtgcatttggagaagttcaattggtaaggcataaatccaccaggaag
gtatatgctatgaagcttctcagcaaatttgaaatgattaagagatccgattctgctttt
ttctgggaagaaagggacatcatggcttttgctaatagtccttgggtcgttcagcttttt
tatgcattccaagatgatcgttatctctacatggtgatggaatacatgcctggtggagat
cttgtaaacctaatgagcaactatgatgtgcctgagaagtgggcacgattctatactgca
gaagtagttcttgctttggatgcaatccattccatgggttttattcatagggatgtgaag
cctgataacatgctgctggataaatctggacatttgaagttagcagattttggtacttgt
atgaagatgaataaggaaggtatggtacgatgtgatacagcagttggaacacctgattat
atttcccctgaagtattgaaatctcaaggtggtgatggttattatggacgagagtgtgac
tggtggtcagttggggtatttttatatgaaatgcttgtaggtgatacacctttttatgca
gattctctggttggaacttacagtaagattatgaaccataaaaattcacttaccttccct
gatgataatgacatatcaaaagaagcaaaaaatcttatttgtgccttccttactgaccga
gaggtgagattagggcgaaatggcgtagaagaaatcaaacgacatctcttctttaaaaat
gatcagtgggcttgggaaacactccgagacactgtagcgccagttgtacctgatttaagt
agtgacattgatacaagtaactttgatgacctggaagaagataaaggagatgaagaaaca
ttccctatacctaaagcttttgttggcaatcaactaccttttgtaggatttacatattat
agcaatcgtagatacttatcttcaacaaatcctaatgataacagaactagctccaatgtg
gataaaagcttgcaggaaaatttgcaaaaaacaatttataagctagaagaacagctgcat
aatgaaatgcaattaaaagatgaaatggagcagaagtgcagaacttcaaacataaaatta
gacaagataatgaaagaattggatgaagaggggaatcaaagaagaaatctagaatctaca
gtgtctcagattgagaaagagaaaatgttactacaacatagaattaatgagtaccaaaga
aaagcagaacaggaaaatgagaagaggagaaatgtagaaaatgaagtttctacattaaag
gatcagttggaagacttaaagaaagtcagtcagaattcgcagcttgctaatgagaaggtg
gcacaattacaaaagcagctagaagaagccaatgacttacttaggacagaatcagacaca
gctgtaagattaaggaagagtcatactgagatgagcaagtcagtcagtcagctagagtcc
ctgaacagagaattgcaggagagaaatagaattttagagaattccaagtcacaaacggac
aaggattattaccagctgcaagctgcattggaagctgaacgaagagacagaggtcatgat
tctgagatgattggagaccttcaagcacggattacatctttacaagaggaggtgaaacat
ctcaaacataatcttgaaagagtggaaggagaaagaaaagaggctcaagacatgcttact
cattcagaaaaggaaaagaataatttagaaatagatttaaactacaaacttaaatcatta
caacaacgattagaacaggagataaatgaacataaagtaaccaaagctcgtttaactgac
aaacatcagtctattgaagaggcaaagtctgttgcaatgtgtgagatggaaaaaaagctg
aaggaagaaagagaagctcgagagaaggctgaaaatagggttgttcagattgagaaacag
tgttccatgctagacgttgatctgaaacaatctcagcagaagcttgagcatttgactgaa
aataaagaaaggatggaggatgaagttaagaatctaactctgcaattggagcaggaatca
aataagcgactgttgttacaaaatgaattgaagactcaagcatttgaggcagacaattta
aaaggtttagaaaagcagatgaaacaggaaataaatactttattggaagcaaagagatta
ttagagtttgagttaggtcagcttacaaaacagtatagaggaaatgaaggacagatgcgg
gagctacaagatcagcttgaagctgagcaatacttctcgacactttataaaacccaggta
aaggaacttaaggaagaaattgaagaaaaaaacagagaaaatttaaagaaaatacaggaa
ctacaaaatgaaaaagaaactcttgctactcagttggatctagcagaaacaaaagctgag
tctgagcagttggcgcgagggcttctagaagagcagtattttgaattgacccaagaaagc
aagaaagctgcttcaagaaatagacaagagattacagataaagatcacactgttagtcgg
ctcgaagaaacgaatagcatgctaaccaaagatattgaattattaagaaaagaaaatgaa
gagttaactgataaaatgaggaagacagaggaagaatataaattgaagaaggaggaggag
atcagtaatcttaaggctgcctatgaaaagaatatcaatacagaacgaacccttaaaaca
caggctgtcaacaagttggcagaaataatgaatcggaaagattttaaaattgatagaaag
aaagctaatacacaggatttgagaaagaaagaaaaggaaaatcgaaagctacaactggaa
ctcaaccaagaaagagagaaattcaaccagatggtggtgaaacatcagaaggaactgaac
gacatgcaagcgcaattgttagaagaatgtacacacaggaatgagcttcagatgcagttg
gctagcaaagagagtgacattgagcaattgcgtgctaaactcttggacctttcggattct
acaagtgttgcaagttttcctagtgctgatgaaactgatggaaaccttccagagtcaaga
atcgaaggttggctctcaataccaaatagaggaaatatcaaacgatatggctggaagaaa
cagtatgttgtggtgagcagcaaaaaaattttgttctataacgatgagcaggataaggag
caatccaatccatctatggtattggacatagataaattgtttcacgttcgacctgtaaca
caaggagatgtgtacagagctgaaactgaagaaattcctaaaatattccagatactatat
gcaaatgaaggtgaatgtagaaaagatgtagatatggaaccagtacaacaagctgaaaaa
actaattttcaaaatcacaaaggccacgagttcattcctacactctaccactttcctgcc
aactgtgaggcctgtgccaaacctctctggcatgtttttaagccaccccctgccctagaa
tgtcgaagatgccatgttaagtgccacagagatcacttagataagaaagaggacttaatt
tctccatgtaaagtaagttatgatgtaacatcagcaagagatatgctgctgttagcatgt
tctcaggatgaacaaaaaaaatgggtaactcatttagtaaagaagatccctaagaatcca
ccatctggttttgttcgtgcatcccctcgaacgctttctacaagatccactgcaaatcaa
tctttccggaaagtggtcaaaaatacgtcaggaaaagctagttaa
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integrated database retrieval system
