Equus caballus (horse): 100034086
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Entry
100034086 CDS
T01058
Symbol
PDE3A
Name
(RefSeq) cGMP-inhibited 3',5'-cyclic phosphodiesterase A
KO
K19021
cGMP-inhibited 3',5'-cyclic phosphodiesterase A [EC:
3.1.4.17
]
Organism
ecb
Equus caballus (horse)
Pathway
ecb00230
Purine metabolism
ecb01100
Metabolic pathways
ecb04022
cGMP-PKG signaling pathway
ecb04024
cAMP signaling pathway
ecb04924
Renin secretion
ecb05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
ecb00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
100034086 (PDE3A)
09130 Environmental Information Processing
09132 Signal transduction
04024 cAMP signaling pathway
100034086 (PDE3A)
04022 cGMP-PKG signaling pathway
100034086 (PDE3A)
09150 Organismal Systems
09152 Endocrine system
04924 Renin secretion
100034086 (PDE3A)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
100034086 (PDE3A)
Enzymes [BR:
ecb01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.17 3',5'-cyclic-nucleotide phosphodiesterase
100034086 (PDE3A)
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Gene cluster
GFIT
Motif
Pfam:
PDEase_I
TgpA_N
Motif
Other DBs
NCBI-GeneID:
100034086
NCBI-ProteinID:
NP_001157449
Ensembl:
ENSECAG00000016360
VGNC:
21243
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Position
6:48266142..48559220
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AA seq
1141 aa
AA seq
DB search
MAVPGEDARVRDKPGHGGASLVPTAGPDCHRRAGPASPRDSGCRGCWGDLVLQPLRRSGK
LSSALCAGSLSFLLALLVRLVRGEIGCDLEPSKEAAAAAAEEEAAPGAGGGVFPGPRGGA
PGGGAPLSPWLQPSALLFSLLCAFFWMGLYLLRAGVRLPLAVALLAACCGGEALVQIGLG
VGDEHLLSLPAAGVVLSCLAAATWLVLRLRLGVLMIALTSAVRTVSLISLERFKVSWRPY
LAYLAGVLGILLARYVEQILPQSAGAAPREHFGSQLIAGTKEDIPLFKRRRRSSSVVSAE
MSGCSSKSHRRTSLPCIPREQLMGHSEWDHKRGPRGSQSSGTSITVDIAVMGEAHGLITD
LLADPSLPPNVCTSLRAVSNLLSTQLTFQAIHKPRVNPVISFSENYTCSDSEESSEKDKL
AIPKRLRRSLPPGLLRRVSSTWTTTTSATGLPTLEPAPVRRDRSASMKLHEAPSSSPDSW
NNPVMMTLTKSRSFTSSYAVSAANHVKARKPNRPGALAKISPLSSPCSSPLQGTPASSPI
SKISAAQFPESSDTTAKQGLSSHRALTYTQSAPDLSPQILPPPVICSSCGRPYSQGTPAD
GPLERGSAAIRTPGRADDTAQVTSDYETNNNSDSSDIVQNEDETECPREPLRKASACGTY
TPETMIFLDKPILAPEPLVMDNLDTIMEQLNTWNFPIFDLVEKIGRKCGRILSQVSYRLF
EDMGLFEAFKIPVREFMNYFHALEIGYREIPYHNRIHATDVLHAVWYLTTQPIPGLSTVV
NDHGSASDSDSDSGFTHGHMGYVFSKMYNVPDDKYGCLSGNIPALELMALYVAAAMHDYD
HPGRTNAFLVATSAPQAVLYNDRSVLENHHAAAAWNLFMSRPEYNFLVNLDHVEFKHFRF
LVIEAILATDLKKHFDFVARFNAKVNDDVGIDWTNENDRLLVCQMCIKLADINGPAKCKE
LHLQWTEGIVNEFYEQGDEEASLGLPISPFMDRSAPQLANLQESFISHIVGPLCNSYDSA
GLMPGKWVEDSDESGDTDDPEEEEEDEAPNEEETCENNESPRKKTFKRRKIYCQITQHLL
QNHKMWKKVIEEEQRLAGIENQSLDQCPQQHPSEQIQAIREEEEEKGKSREEEIPTPKPN
Q
NT seq
3426 nt
NT seq
+upstream
nt +downstream
nt
atggcagtgcccggcgaggacgcccgagtcagggacaagcccggccacggtggggcgagt
ctagtccccacggcgggcccggactgccaccgtcgcgcgggccccgcatcgccgcgggac
tcgggctgccgcggctgctggggagacctggtgctgcagccgctccggcgctccgggaaa
ctttcctcggcgctctgcgcgggctccctgtcctttttgctggcgctgctggtgaggctg
gtccgcggggagatcggctgtgacctggagccgagtaaggaggcggcggcggcggcggcg
gaggaggaagcggccccgggagcaggagggggcgtcttcccggggcctcggggaggtgct
cccgggggcggcgcgccgctcagcccctggctgcagccctcggcgctgctcttcagtctc
ctgtgtgccttcttctggatgggcttgtacctcctgcgcgccggggtgcgcctgcctctg
gccgtcgcgctgctggccgcctgctgcgggggggaagcgctcgtccagattgggctgggc
gtcggggacgagcacttactctcgctccccgccgcgggggtggtgctcagctgcttggcc
gccgcgacatggctggtgctgaggctgaggctgggcgtcctcatgatcgccttgactagc
gcggtcaggaccgtgtccctcatttccttagagaggttcaaggtctcctggagaccttac
ctggcgtacttggccggcgtgctggggatcctcttggccaggtacgtggagcaaatcttg
ccgcagtccgcgggggcggctccgagggagcattttgggtcccagctgattgctgggacc
aaggaagatatcccgctgtttaagaggaggaggcggtccagctctgtggtgtccgccgag
atgtcgggctgtagcagcaagtcccaccggaggacctccctgccctgcataccgagggaa
cagctcatggggcattcagaatgggaccacaaacgggggccaagaggatcacagtcttca
ggaaccagtattactgtggatattgctgtgatgggcgaggctcacggcctcattaccgac
ctcctggcagacccttctctgccccccaatgtgtgcacgtccttgagggcagtgagcaac
ctgctcagcacccagctcaccttccaggctattcacaagcccagggtgaatcctgtcatt
tccttcagtgaaaactacacctgttcagattctgaagaaagctctgaaaaagacaagctg
gcaattcccaagcgcctgagaaggagtttgcccccgggtttgttgagacgagtttcatcg
acttggacaactaccacctcagccacaggtctacccactttggagcctgccccagtacgg
agggaccgtagcgccagcatgaaactacatgaagcgccttcatccagtcctgattcttgg
aataacccagtgatgatgaccctcaccaaaagcagatccttcacttcgtcctacgctgtt
tctgcagctaaccacgtaaaggctagaaagcccaatcgaccaggtgccctagctaaaatt
tcacctctttcctcgccctgctcctcacctctccaagggactcctgccagtagccccatc
agcaaaatttcggcagcgcagtttccagaatcttctgacacaactgccaaacaaggccta
agttctcacagggccttaacttatactcagagcgcccctgacctgtctcctcagatcctg
cctccacctgttatatgtagcagctgcggcagaccgtattcccaagggactcccgctgat
gggcccctggagagaggcagtgcggccattcggactccaggcagagcagatgacactgct
caagttacctctgattatgaaaccaataacaacagtgatagcagtgatattgtacaaaat
gaagatgagactgagtgtccaagagagccactgaggaaagcgtcggcttgcggcacctac
acgcctgagaccatgatattcctggacaaaccaattcttgctcctgaacctcttgtcatg
gataacttggacacaattatggagcagctaaatacttggaattttccaatttttgatttg
gtggaaaaaataggaagaaaatgcggtcgtattcttagtcaggtgtcatacagacttttt
gaagacatgggcctctttgaagcttttaaaattccagttagggaatttatgaattatttt
catgctttggagattggatacagggaaattccttatcataacagaatccatgccactgac
gtcttacatgctgtttggtatctgacgacgcagcctattccaggcctctcaactgtggtt
aatgatcatggatcagcaagtgattcagattctgacagtggatttacacatggacatatg
ggatatgtattctcaaaaatgtataatgtgccagatgataaatacggctgtttgtctgga
aatatccctgccttagagttgatggcactatatgtggctgcagccatgcatgactatgat
cacccaggaaggactaatgctttccttgtggcaactagcgctcctcaggctgtgctctat
aatgatcgttcagttttggagaatcaccatgcagctgctgcctggaatcttttcatgtcc
cggccagaatataacttcttagttaaccttgaccatgtggaatttaagcatttccgtttc
cttgtcattgaggcaattttggccactgacctgaagaaacactttgacttcgtagccaga
tttaatgccaaggtgaatgatgatgttggaatagattggaccaatgaaaatgatcgtcta
ctggtttgtcaaatgtgtataaagttggctgatatcaatgggccagctaaatgtaaagag
ctccatcttcagtggacagagggtattgtcaatgaattttatgaacagggtgatgaagag
gccagccttgggttaccaataagccccttcatggaccgttctgcccctcagttggccaat
cttcaggaatccttcatctctcacattgtgggtcctctgtgcaactcctatgactcagca
ggactgatgccagggaaatgggtggaagacagtgatgagtcaggagatacagatgaccct
gaggaagaggaggaggacgaagcaccaaatgaagaggaaacctgtgaaaataatgaatct
ccaagaaagaaaactttcaaaaggaggaaaatctactgccaaataactcagcacctcctg
cagaaccacaagatgtggaagaaagtcattgaagaggaacagcggttggcgggcatagaa
aatcagtctctggaccagtgcccccagcagcatccctcagaacagatccaggccatcagg
gaagaagaggaagagaaagggaagtcgagagaagaggagatccccaccccaaagccaaac
cagtga
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