Equus caballus (horse): 100034092
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Entry
100034092 CDS
T01058
Symbol
CACNA1S
Name
(RefSeq) voltage-dependent L-type calcium channel subunit alpha-1S
KO
K04857
voltage-dependent calcium channel L type alpha-1S
Organism
ecb
Equus caballus (horse)
Pathway
ecb04010
MAPK signaling pathway
ecb04020
Calcium signaling pathway
ecb04022
cGMP-PKG signaling pathway
ecb04024
cAMP signaling pathway
ecb04260
Cardiac muscle contraction
ecb04261
Adrenergic signaling in cardiomyocytes
ecb04270
Vascular smooth muscle contraction
ecb04723
Retrograde endocannabinoid signaling
ecb04725
Cholinergic synapse
ecb04726
Serotonergic synapse
ecb04727
GABAergic synapse
ecb04911
Insulin secretion
ecb04912
GnRH signaling pathway
ecb04921
Oxytocin signaling pathway
ecb04924
Renin secretion
ecb04925
Aldosterone synthesis and secretion
ecb04927
Cortisol synthesis and secretion
ecb04929
GnRH secretion
ecb04934
Cushing syndrome
ecb04935
Growth hormone synthesis, secretion and action
ecb05010
Alzheimer disease
ecb05020
Prion disease
ecb05022
Pathways of neurodegeneration - multiple diseases
ecb05207
Chemical carcinogenesis - receptor activation
ecb05410
Hypertrophic cardiomyopathy
ecb05412
Arrhythmogenic right ventricular cardiomyopathy
ecb05414
Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
ecb00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
100034092 (CACNA1S)
04020 Calcium signaling pathway
100034092 (CACNA1S)
04024 cAMP signaling pathway
100034092 (CACNA1S)
04022 cGMP-PKG signaling pathway
100034092 (CACNA1S)
09150 Organismal Systems
09152 Endocrine system
04911 Insulin secretion
100034092 (CACNA1S)
04929 GnRH secretion
100034092 (CACNA1S)
04912 GnRH signaling pathway
100034092 (CACNA1S)
04921 Oxytocin signaling pathway
100034092 (CACNA1S)
04935 Growth hormone synthesis, secretion and action
100034092 (CACNA1S)
04924 Renin secretion
100034092 (CACNA1S)
04925 Aldosterone synthesis and secretion
100034092 (CACNA1S)
04927 Cortisol synthesis and secretion
100034092 (CACNA1S)
09153 Circulatory system
04260 Cardiac muscle contraction
100034092 (CACNA1S)
04261 Adrenergic signaling in cardiomyocytes
100034092 (CACNA1S)
04270 Vascular smooth muscle contraction
100034092 (CACNA1S)
09156 Nervous system
04727 GABAergic synapse
100034092 (CACNA1S)
04725 Cholinergic synapse
100034092 (CACNA1S)
04726 Serotonergic synapse
100034092 (CACNA1S)
04723 Retrograde endocannabinoid signaling
100034092 (CACNA1S)
09160 Human Diseases
09161 Cancer: overview
05207 Chemical carcinogenesis - receptor activation
100034092 (CACNA1S)
09164 Neurodegenerative disease
05010 Alzheimer disease
100034092 (CACNA1S)
05020 Prion disease
100034092 (CACNA1S)
05022 Pathways of neurodegeneration - multiple diseases
100034092 (CACNA1S)
09166 Cardiovascular disease
05410 Hypertrophic cardiomyopathy
100034092 (CACNA1S)
05412 Arrhythmogenic right ventricular cardiomyopathy
100034092 (CACNA1S)
05414 Dilated cardiomyopathy
100034092 (CACNA1S)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
100034092 (CACNA1S)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04040 Ion channels [BR:
ecb04040
]
100034092 (CACNA1S)
Ion channels [BR:
ecb04040
]
Voltage-gated cation channels
Calcium channel, voltage-gated (Cav)
100034092 (CACNA1S)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Ion_trans
GPHH
Ca_chan_IQ
PKD_channel
CAC1F_C
Motif
Other DBs
NCBI-GeneID:
100034092
NCBI-ProteinID:
XP_023488199
Ensembl:
ENSECAG00000018762
VGNC:
15987
LinkDB
All DBs
Position
30:complement(29479285..29544420)
Genome browser
AA seq
1872 aa
AA seq
DB search
MEPSSPQDEGQRKKPPKKPVPEILPRPPRALFCLTLQNPLRKACINIVEWKPFETIILLT
IFANCVALAVYLPMPEDDNNTLNLGLEKLEYFFLIVFSIEAAMKIIAYGFLFHQDAYLRS
GWNVLDFIIVFLGVFTVILEQVNIIQSNTAPLSSKGAGLDVKALRAFRVLRPLRLVSGVP
SLQVVLNSIFKAMLPLFHIALLVLFMVIIYAIIGLELFKGKMHKTCYFIGTDIVATVENE
KPSPCARTGSGRPCTINGSECRGGWPGPNHGITHFDNFGFSMLTVYQCITMEGWTEVLYW
VNDAIGNEWPWIYFVTLILLGSFFILNLVLGVLSGEFTKEREKAKSRGTFQKLREKQQLE
EDLRGYMSWITQGEVMDVEDFREGKLSLDEGGSDTESLYEIEGLNKIIQFVRHWRQWNRI
LRWKCHDVVKSRVFYWLVILVVALNTLSIASEHHHQPLWLTHLQDVANRVLLSVFTIEML
MKMYGLGLRQYFMSIFNRFDCFVVCSGILEILLVESGAMTPLGISVLRCIRLLRIFKITK
YWTSLSNLVASLLNSIRSIASLLLLLFLFIIIFALLGMQLFGGRYDFEDTEVRRSNFDNF
PQALISVFQVLTGEDWNSVMYNGIMAYGGPSYPGMFVCIYFIILFVCGNYILLNVFLAIA
VDNLAEAESLTSAQKAKAEEKKRRKMSKGLPDKSEEEKSVMAKKLEQKPKGEGIPTTAKL
KVDEFESNVNEVKDPYPSADFPGDDEEDEPEIPVSPRPRPLAELQLKEKAVPIPEASSFF
IFSPTNKIRVFCHRIVNATWFTNFILLFILLSSAALAAEDPIRAESVRNQILGYFDIAFT
SVFTVEIVLKMTTYGAFLHKGSFCRNYFNILDLVVVAVSLISMGLESSAISVVKILRVLR
VLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVLVTTLLQFMFACIGVQLFKGKFFSCNDL
SKMTEEECRGYYYVYKDGDPTQVELRPREWIHNDFHFDNVLSAMMSLFTVSTFEGWPQLL
YRAIDSHKEDMGPIYNNRVEMAIFFIIYIILIAFFMMNIFVGFVIVTFQEQGETEYKNCE
LDKNQRQCVQYALKARPLRCYIPKNPYQYQVWYAVTSSYFEYLMFALIMLNTICLGMQHY
NQSKEMNHISDVLNVAFTIIFTLEMILKLMAFKARGYFGDPWNVFDFLIVIGSIIDVILS
EIDTFLASSGGLYCLGGGCGNVDPDESARISSAFFRLFRVMRLIKLLSRAEGVRTLLWTF
IKSFQALPYVALLIVMLFFIYAVIGMQMFGKIAMVDGTQINRNNNFQTFPQAVLLLFRCA
TGEAWQEILLACSYGKLCDPESDYAPGEEYTCGTNFAYYYFISFYMLCAFLIINLFVAVI
MDNFDYLTRDWSILGPHHLDEFKAIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKFCP
HRVACKRLVGMNMPLNSDGTVTFNATLFALVRTALKIKTEGNFEQASEELRAIIKKIWKR
TSMKLLDQVIPPIGDDEVTVGKFYATFLIQEHFRKFMKRQEEYYGYRPKKDVVQIQAGLR
TIEEEVAPEIHRTISGDLTAEEELERAMVEAAMEEGIFRRTGGLFGRVDSFLERTNSLPP
IMANQRPLQVTEIEMEELESPVFLENFPQDPSTHPLARANTNNANANVAHGSGNRSNSQA
FSSVHYEREFPEETETPAARGGTFGQARRAPGPYSQPCMEKLKGQLPQRAMPGAQAPAAP
SQSARAEPPLPAERRHTPGSRPEQTPSGSGAEDSPSRCPAPATALLIQEALVRGGLDTLA
ADANFIMVTGQALADACRMEPEEVEVAATELLKGRESPEGMAGAPRCWSLRSSLGSLDQL
PGSQETLIPPEL
NT seq
5619 nt
NT seq
+upstream
nt +downstream
nt
atggagccgtcctcaccccaggatgagggccagaggaagaaaccgcccaagaagccggtc
ccagagattctgccgaggccgccccgggccttgttctgcttgaccctccagaaccctctg
aggaaggcctgcatcaacatcgtggaatggaaacccttcgagaccatcatcttactcacc
atctttgccaactgcgtggccttggccgtgtacttgcccatgccggaggatgacaacaac
actctgaacctcggcctggagaaactggagtatttcttcctcatcgtcttctccatcgaa
gccgccatgaagatcattgcctacggcttcctgttccaccaggacgcctacctgcgcagc
ggctggaatgtgctggacttcatcatcgtcttcctgggggtcttcaccgtgattctggaa
caggtcaacatcatccagagcaacacggcccccctgagcagcaagggcgccggcctggac
gtcaaggccctgcgagctttccgcgtgctcagacccctccggctggtgtcgggggtgccc
agcctgcaggtggtcctaaactccatcttcaaggccatgctgcccctcttccacatcgct
ctgctggtgctcttcatggtcatcatctacgccatcatcgggctggagctcttcaagggc
aaaatgcacaagacctgctacttcatcgggacagatattgtggccacagtggagaacgag
aagccatcgccctgcgccaggacgggctcggggcgcccgtgcaccatcaacggcagcgag
tgccgaggcggctggccgggccccaaccacggcatcacccactttgacaacttcggcttc
tccatgcttaccgtgtaccagtgcatcaccatggagggctggacggaggtcctgtactgg
gtcaacgatgccatcgggaacgagtggccctggatctacttcgtcaccctcatcctgctg
gggtccttcttcatcctcaacctggtgctgggtgtcctgagcggggagttcaccaaggag
cgggagaaggccaagtccagggggaccttccagaagctccgggagaagcagcagctggag
gaggacctgagggggtacatgagctggatcacgcagggcgaggtcatggacgtcgaggac
tttagagaagggaagctgtctttggatgaaggcggctcagacacggagagcctgtatgaa
atcgagggcttgaacaaaatcatccagttcgtccgacactggagacaatggaaccgcatc
ttgcgctggaagtgccacgacgtggtgaagtccagagtcttctattggctggtcatcctg
gtcgtggccctcaacaccctgtccatcgcctccgagcaccaccaccagcctctctggttg
acccacttgcaagatgttgccaaccgggtgctgctgtcggtcttcaccatcgagatgctg
atgaagatgtacgggctgggcctacgccagtacttcatgtccatcttcaaccgcttcgac
tgttttgtggtgtgcagcggcatcctcgagatcctgctggtggagtcaggcgccatgacc
ccgctgggcatctctgtgctgcgctgcatccggcttctcaggatcttcaagatcaccaag
tactggacgtcgctgagcaacctggtggcgtccctgctcaactccatccgctccatcgcc
tcgctgctcctgctactcttcctcttcatcatcatcttcgccctgctgggcatgcagctc
ttcggcggcaggtacgactttgaggacacggaggtgcggcggagcaacttcgacaacttc
ccgcaggccctcatcagcgtcttccaggtcctgacaggtgaggactggaactccgtgatg
tacaacggaatcatggcctacggcgggccgtcctaccccggcatgttcgtgtgcatttat
ttcatcatccttttcgtctgtggcaactacatcctgctcaatgtcttcctggccatcgcc
gtggacaacctggccgaggcggagagcctgacttctgcccagaaggccaaggcggaggag
aaaaaacgcaggaagatgtccaagggtctcccagacaagtcggaggaggagaagtcagtg
atggccaagaagctggaacagaaacccaagggcgagggcatccccaccaccgccaagctg
aaagtcgatgagtttgaatctaatgtcaacgaggtgaaggatccctacccctcggctgac
ttcccaggggatgatgaagaagatgagcccgagatcccagtgagcccccgaccacgcccc
ctggctgagctgcagctgaaggagaaggcagtgcccattccagaagccagctccttcttc
atcttcagccccaccaacaagatccgtgtcttttgtcatcgcatcgtcaatgccacctgg
ttcaccaacttcatcctgctcttcattctgctcagcagtgctgcgctggctgctgaggac
cccatccgggccgagtctgtgagaaatcagatccttgggtattttgacatcgcgttcact
tctgtcttcactgtggagattgtcctcaagatgaccacctacggcgccttcctgcacaag
ggctccttctgccgcaactacttcaacatcctggacctggtggtggtggctgtctccctc
atctccatgggacttgagtccagcgccatctcggtggtgaaaatccttagggtgctgagg
gtgctacgacctctccgagccatcaaccgagccaaagggctgaagcacgtggtgcagtgc
gtgttcgtggccatccgcaccatcgggaacatcgtgctggtcaccacgctcctgcagttc
atgtttgcctgcatcggcgtccagctcttcaaggggaagttcttcagctgcaatgactta
tccaagatgacagaagaggagtgcaggggctattactacgtgtacaaggatggggacccc
acgcaggtggaactgcgtccccgcgagtggatacacaacgatttccacttcgacaacgtg
ctctcggccatgatgtcactcttcacggtctccaccttcgaaggatggcctcagctgctg
tacagagctatagactcgcacaaggaggacatgggccccatctacaacaaccgggtggag
atggccatcttcttcatcatctacatcatcctcattgccttcttcatgatgaacatcttt
gtgggcttcgtcatcgtcaccttccaggagcagggggagaccgagtacaagaactgcgag
ctggacaagaaccagcgccagtgtgtgcagtacgccctgaaggcccgccctctgaggtgc
tacattcccaaaaacccgtaccagtatcaagtgtggtacgcggtcacctcctcctacttt
gaatacctgatgtttgccctcatcatgctcaacaccatctgcctgggcatgcagcactac
aaccagtccaaggagatgaaccacatctcggacgtcctcaacgtggccttcaccatcatt
ttcaccctggagatgatcctcaagctcatggcgttcaaggccaggggttattttggagac
ccctggaatgtgtttgacttcttgattgtcattggcagcatcattgacgtcatcctcagc
gagatcgatactttcctggcctccagcgggggactgtattgcctgggtggaggctgcggg
aacgttgacccggacgagagcgcccgcatctccagcgccttctttcgcctgttccgtgtc
atgaggctgatcaagctgctgagccgggctgagggggtgcgcaccctgctctggaccttc
atcaaatccttccaggccctgccgtacgtggctctgctcatcgtcatgctcttcttcatc
tacgcggtcatcggcatgcagatgttcggcaagattgccatggtggacgggacccaaatc
aaccggaacaataacttccagacctttccgcaggccgtgctgctgctcttcaggtgtgcg
acaggcgaggcgtggcaagagatcctgctggcctgcagctacggcaagctgtgcgacccg
gagtctgactacgccccaggcgaggagtacacgtgcggaaccaacttcgcctattactac
ttcatcagcttctacatgctctgcgccttcctgatcatcaacctctttgtggctgtcatc
atggacaacttcgactacctcacgcgggactggtccatcctgggccctcaccacctggat
gagttcaaggccatctgggcagagtacgacccggaggcgaagggcagaatcaagcacctg
gatgtggtgaccctgctgaggaggatccagccccctctgggctttgggaagttctgcccc
caccgagtagcgtgcaagcggctggtgggcatgaacatgcccctgaacagcgacggcacc
gtcaccttcaatgccaccctcttcgccctggtccgcacggcactcaagatcaagacggaa
ggcaactttgagcaggccagcgaggagctgagggccatcatcaagaagatctggaagaga
accagcatgaagctgctggaccaggtcattcctcccataggagatgacgaggtgacggta
gggaagttctacgccacgttcctcatccaggagcacttccggaagttcatgaagcgccag
gaggagtattatgggtaccggcccaagaaggatgtcgtacagatccaggctggactgcgg
accattgaggaggaagtggcccccgagatccaccgcaccatctcaggagacctgacggcc
gaagaggagcttgagagagccatggtggaggccgcgatggaggaagggatattccggagg
accggaggcctgtttggccgggtggacagcttcctggagaggaccaactccctgcccccc
attatggccaaccagagaccactccaggttaccgagatagagatggaagagctggaatca
cccgtcttcttggagaacttccctcaagatccgagcacccaccctctggctcgtgccaac
accaacaatgccaacgccaacgttgcccatggcagcggcaaccgtagcaacagccaggcg
ttttccagcgtccactatgaaagggagttccctgaagagacagagacgcctgcggccaga
ggaggaaccttcggccaagcgcgaagggccccgggaccctacagccagccctgcatggag
aagctgaagggacagctgccccagagagcaatgcccggagcgcaggcacctgctgccccc
agccagagtgccagggcggagcctcccctgcctgcggagaggaggcacacccctgggtct
cgtcctgagcagacccccagtggcagtggggccgaggacagtccttccaggtgcccagct
ccagccacagccctgctgatccaagaggctctggttcgagggggcctggacaccttggcg
gctgatgctaacttcatcatggtgacgggccaggccctggcagatgcctgccgcatggaa
ccggaggaagtggaggtagcagctacggagctactgaaaggacgagagtccccagagggc
atggccggcgccccgcgatgctggagcctgaggtcctccctgggcagccttgaccagctt
ccgggctcccaggagactctgatcccccccgagctgtga
DBGET
integrated database retrieval system
