KEGG   Equus caballus (horse): 100034198
Entry
100034198         CDS       T01058                                 
Symbol
IGF1
Name
(RefSeq) insulin-like growth factor I precursor
  KO
K05459  insulin-like growth factor 1
Organism
ecb  Equus caballus (horse)
Pathway
ecb01521  EGFR tyrosine kinase inhibitor resistance
ecb01522  Endocrine resistance
ecb04010  MAPK signaling pathway
ecb04014  Ras signaling pathway
ecb04015  Rap1 signaling pathway
ecb04066  HIF-1 signaling pathway
ecb04068  FoxO signaling pathway
ecb04081  Hormone signaling
ecb04114  Oocyte meiosis
ecb04115  p53 signaling pathway
ecb04150  mTOR signaling pathway
ecb04151  PI3K-Akt signaling pathway
ecb04152  AMPK signaling pathway
ecb04211  Longevity regulating pathway
ecb04213  Longevity regulating pathway - multiple species
ecb04510  Focal adhesion
ecb04550  Signaling pathways regulating pluripotency of stem cells
ecb04730  Long-term depression
ecb04750  Inflammatory mediator regulation of TRP channels
ecb04913  Ovarian steroidogenesis
ecb04914  Progesterone-mediated oocyte maturation
ecb04935  Growth hormone synthesis, secretion and action
ecb04960  Aldosterone-regulated sodium reabsorption
ecb05200  Pathways in cancer
ecb05202  Transcriptional misregulation in cancer
ecb05205  Proteoglycans in cancer
ecb05214  Glioma
ecb05215  Prostate cancer
ecb05218  Melanoma
ecb05224  Breast cancer
ecb05410  Hypertrophic cardiomyopathy
ecb05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:ecb00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    100034198 (IGF1)
   04014 Ras signaling pathway
    100034198 (IGF1)
   04015 Rap1 signaling pathway
    100034198 (IGF1)
   04066 HIF-1 signaling pathway
    100034198 (IGF1)
   04068 FoxO signaling pathway
    100034198 (IGF1)
   04151 PI3K-Akt signaling pathway
    100034198 (IGF1)
   04152 AMPK signaling pathway
    100034198 (IGF1)
   04150 mTOR signaling pathway
    100034198 (IGF1)
  09133 Signaling molecules and interaction
   04081 Hormone signaling
    100034198 (IGF1)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    100034198 (IGF1)
   04115 p53 signaling pathway
    100034198 (IGF1)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    100034198 (IGF1)
   04550 Signaling pathways regulating pluripotency of stem cells
    100034198 (IGF1)
 09150 Organismal Systems
  09152 Endocrine system
   04913 Ovarian steroidogenesis
    100034198 (IGF1)
   04914 Progesterone-mediated oocyte maturation
    100034198 (IGF1)
   04935 Growth hormone synthesis, secretion and action
    100034198 (IGF1)
  09155 Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    100034198 (IGF1)
  09156 Nervous system
   04730 Long-term depression
    100034198 (IGF1)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    100034198 (IGF1)
  09149 Aging
   04211 Longevity regulating pathway
    100034198 (IGF1)
   04213 Longevity regulating pathway - multiple species
    100034198 (IGF1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100034198 (IGF1)
   05202 Transcriptional misregulation in cancer
    100034198 (IGF1)
   05205 Proteoglycans in cancer
    100034198 (IGF1)
  09162 Cancer: specific types
   05214 Glioma
    100034198 (IGF1)
   05218 Melanoma
    100034198 (IGF1)
   05215 Prostate cancer
    100034198 (IGF1)
   05224 Breast cancer
    100034198 (IGF1)
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    100034198 (IGF1)
   05414 Dilated cardiomyopathy
    100034198 (IGF1)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    100034198 (IGF1)
   01522 Endocrine resistance
    100034198 (IGF1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and neuropeptides [BR:ecb04052]
    100034198 (IGF1)
Cytokines and neuropeptides [BR:ecb04052]
 Cytokines
  Growth factors (RTK binding)
   100034198 (IGF1)
SSDB
Motif
Pfam: Insulin
Other DBs
NCBI-GeneID: 100034198
NCBI-ProteinID: NP_001075967
Ensembl: ENSECAG00000010109
VGNC: 18967
UniProt: A7LHD8
LinkDB
Position
28:complement(27225722..27301668)
AA seq 153 aa
MGKISSLPTQLFKCCFCDFLKVKMHIMSSSHLFYLALCLLTFTSSATAGPETLCGAELVD
ALQFVCGDRGFYFNKPTGYGSSSRRAPQTGIVDECCFRSCDLRRLEMYCAPLKPAKSARS
VRAQRHTDMPKAQKEVHLKNASRGSAGNKNYRM
NT seq 462 nt   +upstreamnt  +downstreamnt
atgggaaaaatcagcagtcttccaacccaattatttaagtgctgcttttgtgatttcttg
aaggtaaagatgcacatcatgtcctcctcacatctcttctacctggccctgtgcttgctc
accttcaccagctctgccacggctggaccggagacactctgcggggctgagctggtggac
gctcttcagttcgtgtgtggagacaggggcttttatttcaacaagcccacagggtacggc
tccagcagtcggagggcgcctcagacaggcatcgtggacgagtgctgcttccggagctgt
gatctgaggaggctggagatgtactgcgcacccctcaagcctgccaagtcggcccgctcc
gtccgtgcccagcgccacaccgatatgcccaaggctcagaaggaagtacatttgaagaac
gcaagtagagggagtgcgggaaacaagaactacagaatgtag

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