KEGG   Equus caballus (horse): 100034222
Entry
100034222         CDS       T01058                                 
Symbol
IL12B
Name
(RefSeq) interleukin-12 subunit beta precursor
  KO
K05425  interleukin 12B
Organism
ecb  Equus caballus (horse)
Pathway
ecb04060  Cytokine-cytokine receptor interaction
ecb04620  Toll-like receptor signaling pathway
ecb04622  RIG-I-like receptor signaling pathway
ecb04625  C-type lectin receptor signaling pathway
ecb04630  JAK-STAT signaling pathway
ecb04658  Th1 and Th2 cell differentiation
ecb04936  Alcoholic liver disease
ecb04940  Type I diabetes mellitus
ecb05133  Pertussis
ecb05134  Legionellosis
ecb05140  Leishmaniasis
ecb05142  Chagas disease
ecb05143  African trypanosomiasis
ecb05145  Toxoplasmosis
ecb05146  Amoebiasis
ecb05152  Tuberculosis
ecb05162  Measles
ecb05164  Influenza A
ecb05168  Herpes simplex virus 1 infection
ecb05171  Coronavirus disease
ecb05200  Pathways in cancer
ecb05205  Proteoglycans in cancer
ecb05321  Inflammatory bowel disease
ecb05330  Allograft rejection
ecb05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:ecb00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    100034222 (IL12B)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    100034222 (IL12B)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    100034222 (IL12B)
   04622 RIG-I-like receptor signaling pathway
    100034222 (IL12B)
   04625 C-type lectin receptor signaling pathway
    100034222 (IL12B)
   04658 Th1 and Th2 cell differentiation
    100034222 (IL12B)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100034222 (IL12B)
   05205 Proteoglycans in cancer
    100034222 (IL12B)
  09172 Infectious disease: viral
   05171 Coronavirus disease
    100034222 (IL12B)
   05164 Influenza A
    100034222 (IL12B)
   05162 Measles
    100034222 (IL12B)
   05168 Herpes simplex virus 1 infection
    100034222 (IL12B)
  09171 Infectious disease: bacterial
   05133 Pertussis
    100034222 (IL12B)
   05134 Legionellosis
    100034222 (IL12B)
   05152 Tuberculosis
    100034222 (IL12B)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    100034222 (IL12B)
   05145 Toxoplasmosis
    100034222 (IL12B)
   05140 Leishmaniasis
    100034222 (IL12B)
   05142 Chagas disease
    100034222 (IL12B)
   05143 African trypanosomiasis
    100034222 (IL12B)
  09163 Immune disease
   05321 Inflammatory bowel disease
    100034222 (IL12B)
   05330 Allograft rejection
    100034222 (IL12B)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    100034222 (IL12B)
  09167 Endocrine and metabolic disease
   04940 Type I diabetes mellitus
    100034222 (IL12B)
   04936 Alcoholic liver disease
    100034222 (IL12B)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and neuropeptides [BR:ecb04052]
    100034222 (IL12B)
   00536 Glycosaminoglycan binding proteins [BR:ecb00536]
    100034222 (IL12B)
Cytokines and neuropeptides [BR:ecb04052]
 Cytokines
  Interleukins
   100034222 (IL12B)
Glycosaminoglycan binding proteins [BR:ecb00536]
 Heparan sulfate / Heparin
  Cytokines
   100034222 (IL12B)
SSDB
Motif
Pfam: IL12p40_C Ig_5 Ig_3 Ig_4 fn3 Ig_2 Ig_RIMBP2 Ig_NUP210_3rd
Other DBs
NCBI-GeneID: 100034222
NCBI-ProteinID: NP_001075985
Ensembl: ENSECAG00000012803
VGNC: 18994
UniProt: Q9XSQ5
LinkDB
Position
14:19326161..>19334661
AA seq 329 aa
MCHQWLVLSWFSLVLLASPLMAIWELEKDVYVVELDWYPDAPGEMVVLTCNTPEEEGITW
TSAQSNEVLGSGKTLTIQVKEFGDAGWYTCHKGGEVLSHSHLLLHKKEDGIWSTDILKDQ
KESKNKTFLKCEAKNYSGRFTCWWLTAISTDLKFSVKSSRGSSDPRGVTCGAATLSAERV
SVDDREYKKYTVECQEGSACPAAEESLPIEIVVDAVHKLKYENYTSGFFIRDIIKPDPPK
NLQLKPLKNSRQVEVSWEYPETWSTPHSYFSLTFSIQVQGKNKKERKDRLFMDETSATVT
CHKDGQIRVQARDRYYSSSWSEWASVSCS
NT seq 990 nt   +upstreamnt  +downstreamnt
atgtgtcaccagtggttggtcctctcctggttttccctggttttgctggcgtctcccctc
atggccatatgggaactggagaaagatgtgtatgttgtagaattggattggtaccctgat
gcccctggagaaatggtggtcctcacctgcaatacccctgaagaagaaggcatcacctgg
acctcggcccagagcaatgaggtcttaggctctggcaaaaccttgaccatccaagtcaaa
gagtttggagatgctggctggtacacctgtcacaaaggaggcgaggttctgagccattct
cacctgctgcttcacaagaaggaagatggaatttggtccactgacattttaaaagaccag
aaagaatccaaaaataagacctttctaaaatgtgaggcaaagaattattccggacgtttc
acatgctggtggctgacagcaatcagtactgatttgaaattcagtgtcaaaagcagcaga
ggttcctctgacccccgaggggtgacgtgtggagcagcgacactctccgcagagagggtc
agcgtggacgacagggagtataagaagtacacggtggagtgtcaggagggcagtgcctgc
ccggccgccgaggagagcctgcccattgagatcgtggtggatgctgttcacaagctcaag
tatgaaaactacaccagcggcttcttcatcagggacatcatcaaaccagacccacccaag
aacctgcagctgaagccattaaagaattctcggcaggtggaggtcagctgggagtacccc
gagacctggagcaccccacattcctacttctccctgacattctctattcaggtccagggc
aagaacaagaaggaaaggaaagacagactcttcatggatgagacttcagccacagtcaca
tgccacaaggatggccagatccgtgtccaagccagggaccgctactacagctcatcctgg
agcgaatgggcatccgtatcctgcagttag

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