KEGG   Equus caballus (horse): 100049805
Entry
100049805         CDS       T01058                                 
Name
(RefSeq) granzyme B
  KO
K01353  granzyme B [EC:3.4.21.79]
Organism
ecb  Equus caballus (horse)
Pathway
ecb04210  Apoptosis
ecb04650  Natural killer cell mediated cytotoxicity
ecb04940  Type I diabetes mellitus
ecb05202  Transcriptional misregulation in cancer
ecb05320  Autoimmune thyroid disease
ecb05330  Allograft rejection
ecb05332  Graft-versus-host disease
Brite
KEGG Orthology (KO) [BR:ecb00001]
 09140 Cellular Processes
  09143 Cell growth and death
   04210 Apoptosis
    100049805
 09150 Organismal Systems
  09151 Immune system
   04650 Natural killer cell mediated cytotoxicity
    100049805
 09160 Human Diseases
  09161 Cancer: overview
   05202 Transcriptional misregulation in cancer
    100049805
  09163 Immune disease
   05320 Autoimmune thyroid disease
    100049805
   05330 Allograft rejection
    100049805
   05332 Graft-versus-host disease
    100049805
  09167 Endocrine and metabolic disease
   04940 Type I diabetes mellitus
    100049805
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:ecb01002]
    100049805
Enzymes [BR:ecb01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.21  Serine endopeptidases
    3.4.21.79  granzyme B
     100049805
Peptidases and inhibitors [BR:ecb01002]
 Serine peptidases
  Family S1: chymotrypsin family
   100049805
SSDB
Motif
Pfam: Trypsin Trypsin_2 DUF1986 SCAPER_N
Other DBs
NCBI-GeneID: 100049805
NCBI-ProteinID: XP_001488243
Ensembl: ENSECAG00000023062
UniProt: A0A5F5PLG5
LinkDB
Position
1:164922909..164926453
AA seq 250 aa
MQPLLLLLVFLLSPGTEAGEIIGGHEARPHSRPYMAFVQFLVEEKNHRCGGVLVQQDFVL
TAAHCWGSSINVTLGAHNIQKQERTQQVISVKEAIPHPDYKRKKFSNDIMLLKLERKATQ
TAAVRPLSLPWGTAQVRPGEVCSVAGWGRVTRNGRASVTLQEVELTVQQDRVCKSYLRNY
NSTTQLCVGDPKEKKSSFKGDSGGPLVCNNLIQGLVSYGRCNGTPPRAFTKVSSFMPWIK
KTLKATWQSG
NT seq 753 nt   +upstreamnt  +downstreamnt
atgcagcctctcctgctcctgctggtgtttttactgtcccctgggacagaggcaggggag
atcatcgggggacatgaggccaggccccactctcgaccctacatggcatttgttcaattt
ctggttgaagagaaaaatcacaggtgtggcggtgtcctcgtgcaacaggactttgttctg
acggctgctcactgctggggaagctcaatcaacgtgaccctgggggcccacaacatccag
aagcaggagaggacccagcaggtcatctctgtgaaggaagccatcccccacccagactat
aaacgtaagaagttctccaatgacatcatgttgctaaagctggagagaaaggctactcag
actgcagctgtgaggcccctcagcctgccctggggcacagcccaggtaaggcctggagag
gtgtgcagtgtggctggctgggggagagtcacccgaaatggcagagcatcagtcactctg
caggaggtggagctgaccgtgcagcaggaccgcgtgtgcaaatcctacttacgcaattac
aacagtaccactcagctttgtgtgggggacccgaaggaaaagaagtcttcttttaagggg
gactccgggggccctcttgtgtgtaacaacttgatccagggccttgtctcctatggaaga
tgcaacgggactcctccacgggccttcaccaaagtctcaagctttatgccctggataaag
aaaaccttgaaggccacatggcagagtggctaa

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