Equus caballus (horse): 100050119
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Entry
100050119 CDS
T01058
Symbol
SHMT2
Name
(RefSeq) serine hydroxymethyltransferase, mitochondrial isoform X1
KO
K00600
glycine hydroxymethyltransferase [EC:
2.1.2.1
]
Organism
ecb
Equus caballus (horse)
Pathway
ecb00260
Glycine, serine and threonine metabolism
ecb00630
Glyoxylate and dicarboxylate metabolism
ecb00670
One carbon pool by folate
ecb01100
Metabolic pathways
ecb01200
Carbon metabolism
ecb01230
Biosynthesis of amino acids
ecb01240
Biosynthesis of cofactors
ecb01523
Antifolate resistance
ecb04981
Folate transport and metabolism
Module
ecb_M00141
C1-unit interconversion, eukaryotes
Brite
KEGG Orthology (KO) [BR:
ecb00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00630 Glyoxylate and dicarboxylate metabolism
100050119 (SHMT2)
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
100050119 (SHMT2)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
100050119 (SHMT2)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
100050119 (SHMT2)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
100050119 (SHMT2)
Enzymes [BR:
ecb01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.1 glycine hydroxymethyltransferase
100050119 (SHMT2)
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Ortholog
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GFIT
Motif
Pfam:
SHMT
Motif
Other DBs
NCBI-GeneID:
100050119
NCBI-ProteinID:
XP_001488586
Ensembl:
ENSECAG00000021295
VGNC:
22965
LinkDB
All DBs
Position
6:75820466..75825517
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AA seq
504 aa
AA seq
DB search
MLPFSLLWASRPLQRCGQLVRMAIRCQHSEVAQTQTGEATRGWTGQESLSDSDPEMWELL
QREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYYGGAEVVDEIELLCQ
RRALEAFDLDPAQWGVNVQPYSGSPANLAAYTALLQPHDRIMGLDLPDGGHLTHGYMSDV
KRISATSIFFESMPYKLNPKTGLIDYDQLALTARLFRPRLIIAGTSAYARLIDYARMREV
CDEVKAHLLADMAHISGLVAAKVIPSPFKHADVVTTTTHKTLRGARSGLIFYRKGVRAVD
PKSGREIPYTFEDRINFAVFPSLQGGPHNHAIAAVAVALKQACSPMFREYSLQVLKNARA
MADALLERGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLELVSITANKNTCPGDRSAIT
PGGLRLGAPALTSRQFREDDFRRVVDFIDEGVSIGLEVKSKTAKLQDFKSFLLNDPETSR
RLANLRQRVEQFARAFPMPGFDEH
NT seq
1515 nt
NT seq
+upstream
nt +downstream
nt
atgctgcccttctctttgctctgggcaagtcggcctctgcagagatgtggtcagctagtc
aggatggccatacggtgccagcacagtgaagtggcccagacccaaactggagaagcaacc
agaggctggacaggccaggagagtctgtcggacagcgaccctgagatgtgggagctgctg
cagagggagaaggacaggcagtgtcgtggcctggagctcattgcctcagagaacttctgc
agccgagctgcgctggaggccctggggtcctgtctgaacaacaagtactcggagggttat
cctggcaagagatactacgggggagcagaggtggtggacgagatcgagctgctgtgtcag
cgccgggccttggaggcctttgacctggatcctgcacagtggggagtcaatgtccagccc
tactctgggtccccagccaatctggctgcctatacagcccttctgcagcctcatgaccga
atcatggggctggacctgcctgatgggggccatctcacccatggctacatgtctgatgtc
aagcggatctcagccacatccatcttcttcgagtctatgccctataagctgaaccccaaa
accggcctcattgactatgaccagcttgcactgactgctcgacttttccggccgcggctc
attattgctggtaccagtgcctacgcccgcctcattgactacgcccgcatgagagaggta
tgtgatgaggtcaaggcacacctgctggcggacatggcccacatcagtggcctagtggct
gccaaggtgatcccctctcctttcaagcatgcggatgttgtcaccaccaccactcacaag
acccttcgaggggccaggtcaggactcatcttctaccggaagggagtgcgggctgtggac
cccaagtctggccgggagatcccttacacatttgaggaccgaatcaactttgccgtgttc
ccgtccctgcaggggggcccccacaaccatgccattgctgcagtggctgtggccctaaag
caggcctgcagtcccatgttccgggagtactccctgcaggttctgaagaacgctcgcgcc
atggctgatgccctgctcgagcgcggctactcactggtgtctggtggcactgacaaccac
ctggtgctggtggacctgcggcccaagggcctagatggtgctcgagctgagcgggtcctg
gagctcgtgtccatcacggccaacaagaacacctgtcctggagaccgaagtgccatcacg
cctgggggcctgcggcttggggccccagccttgacctctcgtcagttccgtgaggatgac
ttccggagagttgtggactttatagatgaaggtgtcagcatcggcttggaggtgaagagc
aagacggcaaaactccaggatttcaaatccttcctgctcaacgacccagaaacaagtcgt
cggctggccaacctcaggcagcgtgtggagcagtttgccagggccttccccatgcccggt
tttgatgagcactga
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