KEGG   Equus caballus (horse): 100050581
Entry
100050581         CDS       T01058                                 
Symbol
PDHB
Name
(RefSeq) pyruvate dehydrogenase E1 component subunit beta, mitochondrial
  KO
K00162  pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1]
Organism
ecb  Equus caballus (horse)
Pathway
ecb00010  Glycolysis / Gluconeogenesis
ecb00020  Citrate cycle (TCA cycle)
ecb00620  Pyruvate metabolism
ecb00785  Lipoic acid metabolism
ecb01100  Metabolic pathways
ecb01200  Carbon metabolism
ecb01210  2-Oxocarboxylic acid metabolism
ecb04066  HIF-1 signaling pathway
ecb04922  Glucagon signaling pathway
ecb05230  Central carbon metabolism in cancer
ecb05415  Diabetic cardiomyopathy
Module
ecb_M00307  Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:ecb00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00010 Glycolysis / Gluconeogenesis
    100050581 (PDHB)
   00020 Citrate cycle (TCA cycle)
    100050581 (PDHB)
   00620 Pyruvate metabolism
    100050581 (PDHB)
  09108 Metabolism of cofactors and vitamins
   00785 Lipoic acid metabolism
    100050581 (PDHB)
 09130 Environmental Information Processing
  09132 Signal transduction
   04066 HIF-1 signaling pathway
    100050581 (PDHB)
 09150 Organismal Systems
  09152 Endocrine system
   04922 Glucagon signaling pathway
    100050581 (PDHB)
 09160 Human Diseases
  09161 Cancer: overview
   05230 Central carbon metabolism in cancer
    100050581 (PDHB)
  09166 Cardiovascular disease
   05415 Diabetic cardiomyopathy
    100050581 (PDHB)
Enzymes [BR:ecb01000]
 1. Oxidoreductases
  1.2  Acting on the aldehyde or oxo group of donors
   1.2.4  With a disulfide as acceptor
    1.2.4.1  pyruvate dehydrogenase (acetyl-transferring)
     100050581 (PDHB)
SSDB
Motif
Pfam: Transket_pyr Transketolase_C
Other DBs
NCBI-GeneID: 100050581
NCBI-ProteinID: XP_001489101
Ensembl: ENSECAG00000005244
VGNC: 50491
LinkDB
Position
16:31584938..31590000
AA seq 359 aa
MAAVSGLVRRSLEQVSGLLRRRFHRTAPAALQVTVREAINQGMDEELERDEKVFLLGEEV
AQYDGAYKVSRGLWKKYGDKRIIDTPISEMGFAGIAVGAAMAGLRPICEFMTFNFSMQAI
DQVINSAAKTYYMSGGLQPVPIVFRGPNGASAGVAAQHSQCFAAWYGHCPGLKVVSPWNS
EDAKGLIKSAIRDNNPVVVLENELMYGVPFELSSEAQSKDFLVPIGKAKIERQGTHITVV
SHSRPVGHCLEAATVLSKEGIECEVINMRTIRPMDIETIEASVMKTNHLVTVEGGWPQFG
VGAEICARIMEGPAFNFLDAPAVRVTGADVPMPYAKILEDNSVPQVKDIIFAIKKTLNI
NT seq 1080 nt   +upstreamnt  +downstreamnt
atggcggcggtgtcgggtctggtgcggagatcccttgagcaggtctccgggctcctgagg
agacgctttcaccggacggcgccagcggcgctacaggtgacagttcgtgaggctataaat
caaggtatggatgaggagctggaaagagatgagaaagtatttctccttggggaagaagtt
gcccagtatgatggggcatacaaggttagccgaggcctgtggaaaaaatacggagataag
aggatcatagacactcccatatctgagatgggctttgctggaattgctgtgggtgcagct
atggctgggttgcggcccatttgtgaatttatgaccttcaatttttctatgcaagccatt
gaccaggttataaactcagctgcaaagacctactacatgtcagggggcctgcagcctgtg
cccatagtcttcagggggcccaacggcgcctcagctggcgtagctgcccagcactcacag
tgctttgctgcctggtatgggcactgcccgggcttaaaggtggtcagcccctggaattca
gaggatgcaaaaggacttattaaatcagccattcgggataacaatccagtggtggtgcta
gagaatgaattgatgtatggagttccttttgaactttcctcagaagctcagtcaaaagat
tttctggttcctattggaaaagccaaaatagaaaggcaagggacacatataactgtagtt
tcccattcaagacctgtgggccactgcttagaagctgcgacagtgctgtctaaagaggga
attgaatgtgaggtcataaacatgcgaaccatcagaccaatggacattgaaacaatagaa
gccagtgtcatgaagaccaatcacctcgtaactgtggagggaggctggccgcagtttgga
gtgggagctgagatttgtgccaggatcatggaaggccctgcattcaattttctggatgcg
cctgcagttcgtgtcaccggtgctgacgtccctatgccttatgcaaagattctagaagac
aactctgtacctcaggttaaagacatcatatttgcaataaagaagacattaaatatctag

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