Equus caballus (horse): 100051079
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Entry
100051079 CDS
T01058
Symbol
NOS1
Name
(RefSeq) nitric oxide synthase, brain isoform X1
KO
K13240
nitric-oxide synthase, brain [EC:
1.14.13.39
]
Organism
ecb
Equus caballus (horse)
Pathway
ecb00220
Arginine biosynthesis
ecb00330
Arginine and proline metabolism
ecb01100
Metabolic pathways
ecb04020
Calcium signaling pathway
ecb04081
Hormone signaling
ecb04145
Phagosome
ecb04371
Apelin signaling pathway
ecb04713
Circadian entrainment
ecb04730
Long-term depression
ecb04926
Relaxin signaling pathway
ecb04970
Salivary secretion
ecb05010
Alzheimer disease
ecb05014
Amyotrophic lateral sclerosis
ecb05022
Pathways of neurodegeneration - multiple diseases
ecb05410
Hypertrophic cardiomyopathy
ecb05412
Arrhythmogenic right ventricular cardiomyopathy
ecb05414
Dilated cardiomyopathy
ecb05416
Viral myocarditis
Brite
KEGG Orthology (KO) [BR:
ecb00001
]
09100 Metabolism
09105 Amino acid metabolism
00220 Arginine biosynthesis
100051079 (NOS1)
00330 Arginine and proline metabolism
100051079 (NOS1)
09130 Environmental Information Processing
09132 Signal transduction
04371 Apelin signaling pathway
100051079 (NOS1)
04020 Calcium signaling pathway
100051079 (NOS1)
09133 Signaling molecules and interaction
04081 Hormone signaling
100051079 (NOS1)
09140 Cellular Processes
09141 Transport and catabolism
04145 Phagosome
100051079 (NOS1)
09150 Organismal Systems
09152 Endocrine system
04926 Relaxin signaling pathway
100051079 (NOS1)
09154 Digestive system
04970 Salivary secretion
100051079 (NOS1)
09156 Nervous system
04730 Long-term depression
100051079 (NOS1)
09159 Environmental adaptation
04713 Circadian entrainment
100051079 (NOS1)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
100051079 (NOS1)
05014 Amyotrophic lateral sclerosis
100051079 (NOS1)
05022 Pathways of neurodegeneration - multiple diseases
100051079 (NOS1)
09166 Cardiovascular disease
05410 Hypertrophic cardiomyopathy
100051079 (NOS1)
05412 Arrhythmogenic right ventricular cardiomyopathy
100051079 (NOS1)
05414 Dilated cardiomyopathy
100051079 (NOS1)
05416 Viral myocarditis
100051079 (NOS1)
Enzymes [BR:
ecb01000
]
1. Oxidoreductases
1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
1.14.13.39 nitric-oxide synthase (NADPH)
100051079 (NOS1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
NO_synthase
FAD_binding_1
Flavodoxin_1
NAD_binding_1
PDZ
PDZ_6
PDZ_2
Motif
Other DBs
NCBI-GeneID:
100051079
NCBI-ProteinID:
XP_001915005
Ensembl:
ENSECAG00000009126
VGNC:
20813
UniProt:
A0A3Q2HV61
LinkDB
All DBs
Position
8:18462116..18631963
Genome browser
AA seq
1468 aa
AA seq
DB search
MENHMFSVQQIQPNVISVRLFKRKVGGLGFLVKERVSKPPVIISDLIRGGAAEQSGLIQA
GDIILAVNGQPLVDLSYDSALEVLRGIASETHVVLILRGPEGFTTHLETTFTGDGTPKTI
RVTRPLGPPTAAIDLSHQPSASKEQPLTVDGATGPGNGPQHAQDNRQEAGSLCHTNGLAP
RPSSQEPAKKSAGIALQGSGKNNELLREIEPVLSLLASGGKGINGGGPAKMETKDAEVQV
DRDLDGKSHKPLPLGVENDRVFNDLWGKGNVPVVLNNPYSEKEQPPASGKQSPTKNGSPS
KCPRFLKVKNWETDVVLTDTLHLKSTLETGCTEHICMGSIMLPSQHIRRPEDVRTKQQLF
PLAKEFIDQYYSSIKRSGSKAHMERLEEVNKEIETTSTYQLRDTELIYGAKHAWRNASRC
VGRIQWSKLQVFDARDCTTAHGMFNYICNHIKYATNKGNLRSAITIFPQRTDGKHDFRVW
NSQLIRYAGYKQPDGSILGDPANVEFTEICTQQGWKPPRGRFDVLPLLLQANGNDPELFQ
IPPELVLEVPIRHPKFEWFKDLGLKWYGLPAVSNMLLEIGGLEFSACPFSGWYMGTEIGV
RDYCDNSRYNILEEVAKKMNLDLRKTSSLWKDQALVEINIAVLYSFQSDKVTIVDHHSAT
ESFIKHMENEYRCRGGCPADWVWIVPPMSGSITPVFHQEMLNYRLTPSFEYQPDPWNTHV
WKGTNGTPTKRRAIGFKKLAEAVKFSAKLMGQAMAKRVKATILYATETGKSQAYAKTLCE
IFKHAFDAKVMSMEEYDIVHLEHETLVLVVTSTFGNGDPPENGEKFGCALMEMRHPNSVH
EERKYPEPLRFFPRKGPPLPRGDTEVHGLAAARDSQRRSYKVRFNSVSSYSDSRKSSGDG
PDLRDNFESTGPLANVRFSVFGLGSRAYPHFCAFGHAVDTLLEELGGERILKMREGDELC
GQEEAFRTWAKKVFKAACDVFCVGDDVNIEKANNSLISNDRSWKRNKFRLTYVAEAPELT
QGLSNVHKKRVSAARLLSRQNLQSPKSSRSTIFVRLHTNGNQELQYQPGDHLGVFPGNHE
DLVNALIERLEDAPPVNQLVKVELLEERNTALGVISNWTDEHRLPPCTIFQAFKYYLDIT
TPPTPLQLQQFASLATSEKEKQRLLVLSKGLQEYEEWKWGKNPTIVEVLEEFPSIQMPAT
LLLTQLSLLQPRYYSISSSPDMYPDEVHLTVAVVSYRTRDGEGPIHHGVCSSWLNRIQAD
EGVPCFVRGAPSFRLPRNPLVPCILVGPGTGIAPFRSFWQQRQFDIQHKGMSPCPMVLVF
GCRQSKIDHIYKEETLQAKSKGVFRELYTAYSREPDKPKKYVQDVLQEQLAETVYRALKE
QGGHIYVCGDVTMAADVLKAIQRIMTQQGKLSVEDAGVFISRLRDDNRYHEDIFGVTLRT
YEVTNRLRSESIAFIEESKKDTDEVFSS
NT seq
4407 nt
NT seq
+upstream
nt +downstream
nt
atggagaatcacatgtttagtgttcaacaaatccaacccaatgtcatctccgtccgcctc
ttcaagcgcaaagtggggggcctgggattcttggtgaaggagcgggtgagcaagccgccc
gtgatcatctcagacctgattcgagggggtgccgcggagcagagcggcctcatccaggct
ggagacatcattcttgctgtcaatggccagcccctggtggacctgagctatgacagcgcg
ctggaggtcctcaggggcattgcctccgagacccacgtggtcctcattctgaggggtcct
gagggcttcaccacgcacctggagaccaccttcactggagacgggacccctaagaccatc
cgtgtgacacggcccctgggtccccccactgcagccatcgatctgtcccaccagccatcg
gccagcaaggagcagccactcaccgtggatggggccacaggtcctggcaatgggccacag
catgcccaagacaatagacaggaagctggctcgctctgccacaccaacggcctggctccc
aggccctcaagccaggagcctgccaagaaaagtgccgggatcgccctccagggcagcggg
aagaacaatgaactgctcagagagatagagcctgtgctgagccttctcgccagtgggggc
aaaggcatcaatggagggggacctgccaagatggagacaaaagatgcagaagtccaggtt
gacagagacctggatggcaagtcacacaaaccactgcccctcggcgtggagaacgaccga
gtcttcaacgacctgtgggggaagggcaatgtgcccgtcgtcctcaacaacccatattca
gagaaggagcagccccctgcctcgggaaaacagtcccccacaaagaatggcagcccctcc
aagtgcccgcgcttcctcaaggtcaagaactgggagacggacgtggttctcactgacacc
ctccacctcaagagcacgttggaaacgggatgcaccgagcacatctgtatgggctccatc
atgctcccttctcagcacatacgaaggcccgaggacgtccgcacaaagcaacagctcttc
cctctcgccaaagaatttattgatcagtactactcctcaattaaaagatctggctccaaa
gcccacatggagcggctggaagaggtgaacaaagagatcgaaaccaccagcacctaccag
ctcagagacacggagctcatctacggggcgaagcacgcctggcggaacgcctcccgctgc
gtcggcaggatccagtggtccaagctgcaggtgttcgatgcccgcgactgcaccacggct
catgggatgttcaactacatctgtaatcatatcaagtatgccaccaacaaagggaacctc
aggtctgccatcaccatatttccccagaggactgacggcaagcacgacttccgagtctgg
aactcccagctcatccgctatgccggctacaagcagcccgacggctccatcctcggggat
ccagccaatgtggagttcacagagatctgcacacagcagggctggaaaccccccagaggc
cgcttcgacgtcctgccactcctgctccaggccaacggcaacgaccccgagctcttccag
atccctccagagctggtgctggaagtgcccatcagacaccccaagtttgagtggttcaag
gacctgggactgaagtggtacggcctgcccgctgtgtccaacatgcttctggagattggc
ggcctggagttcagtgcctgtcccttcagcggctggtacatgggcacggagattggcgtc
cgtgactactgtgacaactcacgatacaacatcctggaggaagtggccaagaagatgaac
ctggacctgaggaagacgtcctccctgtggaaggaccaggcgctggtggagatcaacatt
gccgttctctacagcttccagagtgacaaagtgaccatcgttgaccaccactctgccact
gagtccttcatcaagcacatggagaatgaataccgctgccgggggggctgccccgctgac
tgggtgtggattgtgccccccatgtctggaagcatcacccctgtcttccaccaggagatg
ctcaactaccggctcaccccctccttcgaataccagcctgatccttggaacacccatgtc
tggaagggtaccaacgggacccccacaaagcggcgagccatcggcttcaagaagctggca
gaagccgtcaagttctcggccaagctgatggggcaggcaatggccaaaagggtcaaggcg
accatcctttacgccacagagacgggcaagtcgcaggcctacgccaaaaccttgtgtgag
atcttcaaacacgcctttgatgccaaggtgatgtccatggaagaatatgacattgtgcac
ctggaacatgaaactctggtcctggtggttaccagcaccttcggcaatggagacccccct
gagaacggagagaaattcggctgtgctttgatggaaatgagacaccccaactctgtgcac
gaggaaaggaagtacccggaacccttgcgtttctttccccgtaaagggcctcccctcccc
cgaggtgacacagaagtccatggtctggctgcagcccgtgacagccagcgcaggagctac
aaggtccgattcaacagtgtttcctcctattccgactcccgcaaatcatcgggcgatggg
ccagacctcagagacaactttgagagtaccgggcccctggcgaatgtgaggttctcagtg
ttcggccttggctcgcgggcctaccctcacttctgcgcctttggacacgccgtggacacc
ctcctggaagagctgggaggagagaggatcctgaagatgagggaaggcgacgagctctgt
gggcaggaagaagctttcaggacctgggccaagaaggtctttaaggcggcctgcgatgtg
ttctgcgtgggagacgatgtcaacattgagaaggcaaacaactccctcatcagcaatgac
cgcagctggaagaggaacaagttccgcctcacctatgtggctgaagctccggaactcaca
caaggtctatccaatgtccacaaaaagcgggtctcagccgctcgactcctcagccgccaa
aaccttcagagtcctaaatccagccgatcaaccatcttcgtgcgtctccacaccaatggg
aatcaggagctgcagtaccagcccggggaccacctgggcgtcttccccggcaaccacgag
gacctcgtgaacgccctgatcgagcggctggaggacgcaccccctgtcaaccagctggtc
aaagtggagctcctggaggagcggaacacggctttgggagtgatcagtaactggacggac
gagcaccgcctcccgccctgcaccatcttccaggccttcaagtactacctggatatcacc
acacccccaacgccgctccagctgcagcagttcgcctccctggccacgagcgagaaagag
aagcagcgtctgctggtcctcagcaagggtttgcaggaatacgaggaatggaaatggggc
aagaaccccaccatcgtggaggtgctggaggagttcccgtccatccagatgcccgccacc
ctgctcctcacccagctgtctctcctgcaacctcgttactattccatcagttcttcccca
gacatgtacccggatgaggtgcacctcaccgtggccgtcgtctcctaccgcacgcgagat
ggagaagggccaattcaccacggcgtgtgctcctcctggctcaaccggatacaggctgac
gaaggggtcccctgtttcgtgagaggcgcgcccagcttccgcctgccccgaaatcccctg
gtgccatgcattctggttggcccgggcactggcattgcccctttccgaagcttctggcag
cagcggcagtttgatatccaacacaaaggaatgagtccctgccccatggtcctggtcttc
gggtgccggcagtccaagatagaccacatctacaaggaggagaccctacaggccaagagc
aagggggtcttcagagaactgtacacggcctactcccgggagccagacaaaccaaagaag
tacgtgcaggacgtcctgcaggagcagctggcggaaaccgtgtaccgagccctgaaggag
caaggaggccacatttacgtctgtggggacgtcacgatggccgccgatgtcctcaaagcc
atccagcgcatcatgacccagcaggggaaactctcggtggaggacgccggcgtgttcatc
agcaggctgagggatgacaaccggtatcatgaggatattttcggggtcaccctgcgaacg
tacgaagtgaccaaccgccttagatctgaatccattgccttcatcgaggagagcaaaaaa
gacacggacgaggttttcagctcctaa
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integrated database retrieval system
