Equus caballus (horse): 100051186
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Entry
100051186 CDS
T01058
Symbol
CACNA1D
Name
(RefSeq) voltage-dependent L-type calcium channel subunit alpha-1D isoform X1
KO
K04851
voltage-dependent calcium channel L type alpha-1D
Organism
ecb
Equus caballus (horse)
Pathway
ecb04010
MAPK signaling pathway
ecb04020
Calcium signaling pathway
ecb04022
cGMP-PKG signaling pathway
ecb04024
cAMP signaling pathway
ecb04218
Cellular senescence
ecb04260
Cardiac muscle contraction
ecb04261
Adrenergic signaling in cardiomyocytes
ecb04270
Vascular smooth muscle contraction
ecb04530
Tight junction
ecb04713
Circadian entrainment
ecb04723
Retrograde endocannabinoid signaling
ecb04724
Glutamatergic synapse
ecb04725
Cholinergic synapse
ecb04726
Serotonergic synapse
ecb04727
GABAergic synapse
ecb04728
Dopaminergic synapse
ecb04911
Insulin secretion
ecb04912
GnRH signaling pathway
ecb04921
Oxytocin signaling pathway
ecb04924
Renin secretion
ecb04925
Aldosterone synthesis and secretion
ecb04927
Cortisol synthesis and secretion
ecb04929
GnRH secretion
ecb04930
Type II diabetes mellitus
ecb04934
Cushing syndrome
ecb04935
Growth hormone synthesis, secretion and action
ecb04973
Carbohydrate digestion and absorption
ecb05010
Alzheimer disease
ecb05020
Prion disease
ecb05022
Pathways of neurodegeneration - multiple diseases
ecb05031
Amphetamine addiction
ecb05207
Chemical carcinogenesis - receptor activation
ecb05410
Hypertrophic cardiomyopathy
ecb05412
Arrhythmogenic right ventricular cardiomyopathy
ecb05414
Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
ecb00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
100051186 (CACNA1D)
04020 Calcium signaling pathway
100051186 (CACNA1D)
04024 cAMP signaling pathway
100051186 (CACNA1D)
04022 cGMP-PKG signaling pathway
100051186 (CACNA1D)
09140 Cellular Processes
09143 Cell growth and death
04218 Cellular senescence
100051186 (CACNA1D)
09144 Cellular community - eukaryotes
04530 Tight junction
100051186 (CACNA1D)
09150 Organismal Systems
09152 Endocrine system
04911 Insulin secretion
100051186 (CACNA1D)
04929 GnRH secretion
100051186 (CACNA1D)
04912 GnRH signaling pathway
100051186 (CACNA1D)
04921 Oxytocin signaling pathway
100051186 (CACNA1D)
04935 Growth hormone synthesis, secretion and action
100051186 (CACNA1D)
04924 Renin secretion
100051186 (CACNA1D)
04925 Aldosterone synthesis and secretion
100051186 (CACNA1D)
04927 Cortisol synthesis and secretion
100051186 (CACNA1D)
09153 Circulatory system
04260 Cardiac muscle contraction
100051186 (CACNA1D)
04261 Adrenergic signaling in cardiomyocytes
100051186 (CACNA1D)
04270 Vascular smooth muscle contraction
100051186 (CACNA1D)
09154 Digestive system
04973 Carbohydrate digestion and absorption
100051186 (CACNA1D)
09156 Nervous system
04724 Glutamatergic synapse
100051186 (CACNA1D)
04727 GABAergic synapse
100051186 (CACNA1D)
04725 Cholinergic synapse
100051186 (CACNA1D)
04728 Dopaminergic synapse
100051186 (CACNA1D)
04726 Serotonergic synapse
100051186 (CACNA1D)
04723 Retrograde endocannabinoid signaling
100051186 (CACNA1D)
09159 Environmental adaptation
04713 Circadian entrainment
100051186 (CACNA1D)
09160 Human Diseases
09161 Cancer: overview
05207 Chemical carcinogenesis - receptor activation
100051186 (CACNA1D)
09164 Neurodegenerative disease
05010 Alzheimer disease
100051186 (CACNA1D)
05020 Prion disease
100051186 (CACNA1D)
05022 Pathways of neurodegeneration - multiple diseases
100051186 (CACNA1D)
09165 Substance dependence
05031 Amphetamine addiction
100051186 (CACNA1D)
09166 Cardiovascular disease
05410 Hypertrophic cardiomyopathy
100051186 (CACNA1D)
05412 Arrhythmogenic right ventricular cardiomyopathy
100051186 (CACNA1D)
05414 Dilated cardiomyopathy
100051186 (CACNA1D)
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
100051186 (CACNA1D)
04934 Cushing syndrome
100051186 (CACNA1D)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04040 Ion channels [BR:
ecb04040
]
100051186 (CACNA1D)
Ion channels [BR:
ecb04040
]
Voltage-gated cation channels
Calcium channel, voltage-gated (Cav)
100051186 (CACNA1D)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Ion_trans
CAC1F_C
Ca_chan_IQ
GPHH
PKD_channel
Motif
Other DBs
NCBI-GeneID:
100051186
NCBI-ProteinID:
XP_023476031
Ensembl:
ENSECAG00000015892
VGNC:
15983
LinkDB
All DBs
Position
16:complement(35578437..35899181)
Genome browser
AA seq
2181 aa
AA seq
DB search
MMMMMMMKKMQHQRQQQADHANEANYARSTRLPLSGEGPASQPNSSKQTVLSWQAAIDAA
RQAKAAQTMSASAPPPVGSLSQRKRQQYAKSKKQGNSSNSRPARALFCLSLNNPIRRACI
SIVEWKPFDIFILLAIFANCVALAIYIPFPEDDSNSTNHNLEKVEYAFLIIFTVETFLKI
IAYGLLLHPNAYVRNGWNLLDFVIVIVGLFSVILEQLTKETEGGNHSSGKSGGFDVKALR
AFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFIGKMHKT
CFFADSDVVAEEDPAPCAFSGNGRQCTANGTECRSGWVGPNGGITNFDNFAFAMLTVFQC
ITMEGWTDVLYWMNDAMGFELPWVYFVSLVIFGSFFVLNLVLGVLSGEFSKEREKAKARG
DFQKLREKQQLEEDLKGYLDWITQAEDIDPENEEEGGEESKRNTSMPTSETESVNTENVS
GEGESQGCCGSLWCWWRRRGAAKAGPSGCRRWGQAISKSKLSRRWRRWNRFNRRRCRAAV
KSVTFYWLVIVLVFLNTLTISSEHYNQPDWLTQIQDIANKVLLALFTCEMLVKMYSLGLQ
AYFVSLFNRFDCFVVCGGITETILVELEIMSPLGISVFRCVRLLRIFKVTRHWTSLSNLV
ASLLNSMKSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDETQTKRSTFDNFPQALLTVFQ
ILTGEDWNAVMYDGIMAYGGPSSSGMIVCIYFIILFICGNYILLNVFLAIAVDNLADAES
LNTAQKEEAEEKERKKIARKESLENKKTNKPEVNQIANSDNKVTIDDYREEDEDKDPYPP
CDVPVGEEEEEEEEDEPEVPAGPRPRRISELNMKEKIAPIPEGSAFFILSKTNPIRVGCH
KLINHHIFTNLILVFIMLSSAALAAEDPIRSHSFRNTILGYFDYAFTAIFTVEILLKMTT
FGAFLHKGAFCRNYFNLLDMLVVGVSLVSFGIQSSAISVVKILRVLRVLRPLRAINRAKG
LKHVVQCVFVAIRTIGNIMIVTTLLQFMFACIGVQLFKGKFYRCTDEAKSNPEECRGLFI
LYKDGDVDNPVVRERIWQNSDFNFDNVLSAMMALFTVSTFEGWPALLYKAIDSNGENVGP
IYNYRVEISIFFIIYIIIVAFFMMNIFVGFVIVTFQEQGEKEYKNCELDKNQRQCVEYAL
KARPLRRYIPKNPYQYKFWYVVNSSPFEYMMFVLIMLNTLCLAMQHYEQSKMFNDAMDIL
NMVFTGVFTVEMVLKVIAFKPKHYFTDAWNTFDALIVVGSVVDIAITEVNPTESENVPVP
TATPGNSEESNRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIAML
FFIYAVIGMQMFGKVAMRDNNQINRNNNFQTFPQAVLLLFRCATGEAWQEIMLACLPGKL
CDPESDYNPGEEYTCGSNFAIVYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPH
HLDEFKRIWSEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVAMNMPLNS
DGTVMFNATLFALVRTALKIKTEGNLEQANEELRAVIKKIWKKTSMKLLDQVVPPAGDDE
VTVGKFYATFLIQDYFRKFKKRKEQGLVGKYPAKNTTIALQAGLRTLHDIGPEIRRAISC
DLQDDEPEETKREEEEDVFKRNGALLGNHVNHVNSDRRDSLQQTNTTHRPLHVQRPSIPP
ASDTEKPLFPPAGNSVCHNHHNHNSIGKQVPSSTNANLNNANMSKAAPGKRPSIGNLEHV
SENGHHSSHKHDREPQRRSSIKRTRYYETYIRSDSGDEQFPTICREDPEIHGYFRDARCW
GEQEYFSGEECYEDDSSPTWSRQNYSYYNRYPGSNLDFERPRGYHHPQSFLEDDDSPVCY
DSRRSPRRRLLPPTPTSHRRSSFNFECLRRQSSQEEVSPSPAFPHRTALPLHLMQQQIMA
VAGLDSSKAQKYSPSHSTRSWATPPATPPYRDWTPCYTPLIQVERPEALDQVNGSLPSLH
RSSWYTDEPGISYRTFTPASLTVPSSFRNKNSDKQRSADSLVEAVLISEGLGRYARDPKF
VSATKHEIADACDLTIDEMESAASNLLNGNMHPRANGDVGPGSHRQDFELQDFGPGYSDE
EPDPGRDEEDLADEMICITTL
NT seq
6546 nt
NT seq
+upstream
nt +downstream
nt
atgatgatgatgatgatgatgaaaaaaatgcagcatcaacggcagcagcaagcggaccac
gcgaacgaggcaaactatgcaagaagcaccagactgcctctttctggtgaaggaccagct
tctcagccgaatagctccaagcagaccgtcctgtcttggcaagctgcaatcgatgctgct
agacaggccaaggctgcccaaactatgagcgcctctgcacccccacctgtaggatctctc
tcccaaagaaaacgtcagcaatacgccaagagcaaaaaacagggtaactcgtccaacagc
agacctgctcgagccctcttctgcttgtcactcaataaccccatccgaagagcctgcatt
agcatagtggaatggaaaccatttgacatatttatattattggctatttttgccaattgt
gtggccttagctatttacatcccattccctgaagatgattctaattcaacaaatcataac
ttggaaaaagtagaatatgccttcctgattatttttacagtcgagacctttttgaagatt
atagcatatggattattgctacatcctaatgcttatgttagaaatggatggaatttactg
gattttgttatagtaatagtaggattgtttagtgtaattttggaacaattaaccaaagaa
acagaaggcggtaaccactccagtggcaaatcaggaggctttgatgtcaaagccctccgc
gcctttcgagtgttacgaccacttcgactagtatcaggagtgcccagtttacaagttgtc
ctgaactccattataaaagccatggtccccctccttcacatcgcccttttggtattattc
gtaatcataatctatgctattataggattggaactttttattggaaaaatgcacaaaaca
tgtttttttgctgactcagatgtcgtagctgaagaggacccagcgccatgtgcgttctca
gggaatggacgccagtgtaccgccaatggcacagagtgtagaagtggctgggttggccca
aatggaggcatcaccaactttgataactttgcctttgcgatgctcactgtgtttcagtgc
atcaccatggagggctggacagatgtgctctactggatgaatgatgctatgggatttgaa
ttgccctgggtgtattttgtcagtctcgtcatctttgggtcatttttcgtactaaatctt
gtacttggtgtattgagcggagaattctcaaaggaaagagagaaggctaaagcacgggga
gatttccagaagctccgggagaagcagcagctagaagaggatctgaagggttacttggat
tggattacccaagcggaagatattgaccccgagaatgaggaagaaggtggagaggagagc
aaacgcaataccagcatgcccaccagcgagaccgagtctgtgaacacggagaacgtgagt
ggagaaggcgagagccagggctgctgtggaagtctctggtgctggtggagaagaagagga
gccgccaaggctgggccctcggggtgtcggcggtggggtcaagccatctcaaagtccaag
ctcagccgtcgctggcgtcgctggaaccgtttcaatcgcagaaggtgtagggctgccgtg
aagtctgtcacgttttactggctggttattgtcctggtgtttctcaacaccttaaccatt
tcctccgagcactacaaccagcctgactggttgacacagattcaagatatcgctaacaaa
gtcctcttggctctgttcacctgtgagatgctggtaaaaatgtacagcttgggtcttcag
gcatatttcgtctctctctttaatcgatttgactgcttcgtggtgtgtggtggaattacc
gaaacgatcttggtggagctggaaatcatgtctcccctgggcatctctgtgtttcggtgt
gtgcgcctcttacgaattttcaaagtgaccaggcactggacttccctgagcaacttggtg
gcatccttgttgaactccatgaagtccatcgcttcactgttgctcttgctgtttctcttc
atcatcatcttttccttgcttgggatgcagctgtttggcggcaagtttaattttgacgaa
acacaaaccaagcgaagcacctttgacaatttcccccaagcacttctcacagtgttccag
attctgacgggtgaagactggaatgctgtaatgtacgatggcatcatggcgtatgggggc
ccgtcatcttcgggaatgatcgtctgcatctacttcatcatcctcttcatttgcggtaac
tatattctactgaatgtcttcttggccatcgctgtagacaatttggctgatgctgaaagt
ttgaatactgctcagaaagaggaagccgaagagaaggagaggaaaaagattgccagaaaa
gagagcctggaaaataaaaagaccaacaaaccggaagtcaaccagatagccaacagtgac
aacaaagttacaatcgatgactaccgagaagaagatgaggacaaggacccctacccgcct
tgtgatgtgccagtaggtgaagaggaagaggaggaggaggaggatgaacctgaggttcct
gctggcccccgtcctcgcagaatctcggagttgaacatgaaggagaaaatcgcccccatt
cctgaagggagcgctttcttcattcttagcaagaccaacccgatccgcgtgggctgtcac
aagctcatcaaccaccacatcttcaccaacctcatccttgtcttcatcatgctgagcagt
gctgccctcgccgccgaggaccccatccgcagccactctttccggaacactatactgggt
tactttgactatgctttcacagccatctttactgttgaaatcctgttaaagatgacgacc
tttggagctttcctccacaaaggggctttctgcaggaactacttcaatttgctggatatg
ctggttgttggggtgtctctggtgtcatttgggatccaatccagtgccatctccgttgtg
aagattctgagggtcctaagggtcctaaggccactcagggcaatcaacagagcgaaagga
cttaagcatgtcgtccagtgtgtcttcgtggccatccggacaattggcaacatcatgatc
gtcaccacccttctccagttcatgtttgcctgcatcggggtccagttgtttaagggaaag
ttttatcgctgcacagatgaagccaaaagtaacccagaagaatgcaggggcctcttcatc
ctctacaaggatggggatgtcgataaccctgtggtccgtgagaggatctggcaaaacagt
gatttcaactttgacaacgtcctttctgctatgatggcgcttttcacggtctccacgttt
gagggctggcctgcgttgctgtataaagccatcgactcgaatggagagaatgttggcccg
atctacaactaccgcgtggagatctccatcttcttcatcatctacatcatcatcgtagcc
ttcttcatgatgaacatctttgtgggcttcgtcatcgtcacgtttcaggagcagggagag
aaagagtataagaactgtgagctggacaaaaatcagcgtcagtgtgtcgaatacgccttg
aaagcacgtcccttgcggagatacatccccaaaaacccttaccagtacaagttctggtac
gtggtgaactcctcgcctttcgaatacatgatgtttgtcctcatcatgctcaacacactc
tgcttggccatgcagcactatgagcagtccaagatgtttaatgatgccatggacattctg
aacatggtcttcactggggtgttcactgtcgagatggttctgaaagtcattgcatttaaa
cctaagcactatttcactgatgcatggaacacttttgatgccttgattgttgttggtagc
gtcgttgatattgctataactgaagtgaatccaactgaaagtgaaaatgtccctgtccca
actgctactccagggaactctgaagagagcaatagaatctccatcacctttttccgtctt
ttccgagtgatgcgattggtgaagcttctcagcaggggggaaggcatccggacattgctg
tggacttttattaagtccttccaggcgctcccctatgtggcccttctcatagccatgttg
ttcttcatctatgcagttattggcatgcagatgtttgggaaagttgccatgagagataac
aaccagatcaacaggaacaacaatttccagacctttccccaggcggtgctgctgctcttc
aggtgtgcaacgggtgaggcctggcaggagatcatgctggcctgcctcccggggaagctc
tgcgaccccgagtcggattacaaccccggggaggagtacacgtgtggcagcaacttcgcc
attgtttatttcatcagtttttacatgctctgcgcatttctgatcatcaatctgtttgta
gcagtcatcatggataattttgattatctgacccgggactggtctattctggggcctcac
catttagacgaattcaaaagaatatggtcagaatatgaccctgaggcaaagggaaggatc
aagcacctcgatgtggtgacactgctgcgccgcatccagcctcccctggggtttgggaaa
ttgtgcccacacagagtagcttgtaagagacttgttgccatgaacatgcctctgaacagt
gacgggacagtcatgtttaatgcaaccctctttgctctggttcgaacagctcttaaaatc
aagaccgaagggaacctggaacaagctaatgaggaactccgagctgtaataaagaaaatc
tggaagaaaaccagcatgaaactacttgaccaagttgtccctccagctggtgatgatgag
gtaaccgtggggaagttctatgccactttcctgatacaggactactttaggaaattcaag
aaacggaaagaacaaggactggtgggaaagtaccctgcgaagaacaccacaattgcccta
caggcgggattaaggacactgcatgacattgggcctgaaatccggcgtgctatatcatgc
gatttgcaagacgatgagcccgaagaaacaaaacgagaagaagaagaagatgtattcaaa
agaaatggtgccctgcttggaaaccatgtcaatcatgttaatagtgataggagagattcc
cttcagcagaccaataccacccaccgtcccctgcatgtccaaaggccttcaattccacct
gcaagtgatactgagaaaccgctgtttcctccagcaggaaattcggtgtgtcataaccat
cataaccataattccataggaaagcaagttcccagctcaacaaatgccaatctcaataat
gccaatatgtccaaagctgcccctggaaagcggcccagcattgggaaccttgagcatgtg
tctgaaaacgggcatcattcctcccacaagcatgaccgtgagcctcaaagaaggtccagt
attaaaagaacccgctattatgaaacgtacattaggtccgactcaggagatgagcagttc
ccaactatctgccgggaagacccggagatacatggctacttcagggacgcccgctgctgg
ggggaacaggagtatttcagtggcgaggagtgctatgaggatgacagctcaccaacctgg
agcaggcaaaactatagctactacaaccgatatccaggcagcaacttggacttcgagcgg
cctcgaggctaccatcacccccaaagcttcttggaggacgatgactcacctgtttgctat
gattcccggagatctccaaggagacgcctgctacctcccaccccaacatcccaccggagg
tcctccttcaactttgagtgcctgcgccggcagagcagccaggaggaggtgtcgccatcc
cccgccttcccccaccgcacggccctgcctctgcacctgatgcagcaacagatcatggca
gttgcaggcctagattcaagtaaggcccagaagtactcgccaagccactcaacccggtcg
tgggccacccctccagcgacccctccgtaccgggactggacaccatgctacactcccctg
atccaggttgagcggccggaagccctggaccaggtcaacggtagcctgccgtccctgcac
cgcagctcatggtacacggatgagcctggcatctcctatcggactttcacaccagccagc
ctaactgtccccagcagcttccgcaacaaaaacagcgacaagcagaggagtgcagacagc
ttggtggaggcagtcctgatatctgaaggcttaggacggtatgcaagggacccaaagttc
gtgtcggcgacaaaacacgagatcgccgatgcctgtgacctaaccatcgatgagatggag
agtgcagccagcaacctgcttaatgggaacatgcatccccgggccaacggggacgttggc
cccggctcgcaccggcaggactttgaactccaggactttgggccaggctacagcgacgaa
gagccagaccccgggagagatgaggaggacctggcagatgaaatgatatgcatcactacc
ctgtag
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integrated database retrieval system