Equus caballus (horse): 100051344
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Entry
100051344 CDS
T01058
Symbol
PDE4D
Name
(RefSeq) cAMP-specific 3',5'-cyclic phosphodiesterase 4D
KO
K13293
cAMP-specific phosphodiesterase 4 [EC:
3.1.4.53
]
Organism
ecb
Equus caballus (horse)
Pathway
ecb00230
Purine metabolism
ecb01100
Metabolic pathways
ecb04024
cAMP signaling pathway
ecb04928
Parathyroid hormone synthesis, secretion and action
ecb05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
ecb00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
100051344 (PDE4D)
09130 Environmental Information Processing
09132 Signal transduction
04024 cAMP signaling pathway
100051344 (PDE4D)
09150 Organismal Systems
09152 Endocrine system
04928 Parathyroid hormone synthesis, secretion and action
100051344 (PDE4D)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
100051344 (PDE4D)
Enzymes [BR:
ecb01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.53 3',5'-cyclic-AMP phosphodiesterase
100051344 (PDE4D)
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Gene cluster
GFIT
Motif
Pfam:
PDEase_I
PDE4_UCR
Motif
Other DBs
NCBI-GeneID:
100051344
NCBI-ProteinID:
NP_001229433
Ensembl:
ENSECAG00000013771
VGNC:
21246
UniProt:
A0A5F5Q0J1
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Position
21:13132515..14494161
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AA seq
748 aa
AA seq
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MKRNTCDLLSRSKSASEETLHSSNEEEDPFRGMEPYLVRRLSCRSVQLPPLAFRQLEQAD
LKSESENIQRPTSLPLKILPLIAITSADSSGFDVDNGTSSGRSPLDPMTSPGSGLILQAN
FVHSQRRESFLYRSDSDYDLSPKSMSRNSSIASDIHGDDLIVTPFAQVLASLRTVRNNFA
ALTNLQDRAPSKRSPMCNQPSINKATITEEAYQKLASETLEELDWCLDQLETLQTRHSVS
EMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQHEVEIPSPTQKEKEKKKRPM
SQISGVKKLMHSSSLTNSSIPRFGVKTEQEDVLAKELEDVNKWGLHVFRIAELSGNRPLT
VIMHTIFQERDLLKTFKIPVDTLITYLMTLEDHYHADVAYHNNIHAADVVQSTHVLLSTP
ALEAVFTDLEILAAIFASAIHDVDHPGVSNQFLINTNSELALMYNDSSVLENHHLAVGFK
LLQEENCDIFQNLTKKQRQSLRKMVIDIVLATDMSKHMNLLADLKTMVETKKVTSSGVLL
LDNYSDRIQVLQNMVHCADLSNPTKPLQLYRQWTDRIMEEFFRQGDRERERGMEISPMCD
KHNASVEKSQVGFIDYIVHPLWETWADLVHPDAQDILDTLEDNREWYQSTIPQSPSPAPD
DQEEGRQGQTEKFQFELTLEEDGESDTEKDSGSQVEEDTSCSDSKTLCTQDSESTEIPLD
EQVEEEAVGEEEESQPEACAAEDRSPDT
NT seq
2247 nt
NT seq
+upstream
nt +downstream
nt
atgaaaagaaatacctgtgatttgctttctcggagcaaaagtgcctctgaggaaacactg
cattccagtaatgaggaggaagaccctttccgaggaatggagccctatctcgtacggaga
ctttcttgccgcagtgttcagcttcccccactcgcattccgacagttggaacaagctgac
ttgaaaagtgagtcagagaacattcaaagaccaaccagcctccccctgaagattctacca
ctgattgctatcacttccgcagactccagtggttttgatgtggacaatggcacatcttcg
ggacggagtcccttggatcccatgaccagcccaggatccgggctaattctccaagcaaac
tttgtccacagtcaacgtcgggagtccttcctgtatcgatccgacagcgattatgacctc
tctccaaagtctatgtctcggaactcctccattgccagtgatatacacggagatgacttg
attgtgactccatttgctcaggtcttagcgagcctgcgaactgtacgaaacaactttgct
gcgttaactaatttgcaagatcgagcacctagcaaaagatcacccatgtgcaaccaacca
tccatcaacaaagccaccataacagaggaggcctatcagaaactggccagcgagaccctg
gaggagctggactggtgtctggaccagctagagaccctgcagaccaggcactccgtcagt
gagatggcctccaacaagtttaaaaggatgcttaatcgggagctcacccatctctctgaa
atgagtcggtctggaaatcaagtgtcagagtatatatcaaacacattcttagataagcaa
catgaagtggaaattccttctccaactcagaaggaaaaggagaaaaagaaaaggccgatg
tctcagatcagtggggtcaagaagttgatgcacagctccagtttgactaattccagcatc
ccaaggtttggggttaaaactgaacaagaagacgtccttgccaaggaactagaagatgtg
aacaaatggggtcttcatgttttcagaatagcagagttgtctggtaaccggcctttgact
gttatcatgcacaccatttttcaggaacgggatttattaaaaacatttaaaattccagta
gacactttaatcacataccttatgaccctggaagaccattaccacgctgatgtggcctac
cacaacaatattcatgctgcagatgttgtccagtcgacgcatgtgctgttatctacacct
gctttggaggctgtgtttacagatttggagattcttgcagcaatttttgctagtgcaata
catgatgtagatcatcctggtgtgtcaaatcagtttctgatcaatacaaactctgaactt
gccttgatgtacaatgattcttctgtcttggagaaccatcatttggctgtgggctttaag
ttgcttcaggaagaaaactgtgacattttccagaatttgacgaaaaagcaaagacaatca
ttaaggaaaatggtcattgacatcgtacttgcaacagacatgtcaaaacacatgaacctc
ctggctgatttgaaaacaatggttgaaacaaagaaggtgacaagttctggagttcttctt
cttgataattattctgataggattcaggtccttcagaatatggtgcattgtgcagacctg
agcaacccgacaaagcccctgcagctgtaccgccagtggacggaccgcatcatggaggag
ttcttccgccaaggagaccgggagagggagcggggcatggagataagtcccatgtgtgac
aagcacaacgcgtctgtggaaaaatcacaggttggcttcatagactatattgttcatcct
ctctgggagacgtgggcagacctcgtccatcctgatgcccaggacattttggacactttg
gaggacaatcgtgaatggtaccagagcacaattcctcagagcccctccccagcgcctgat
gaccaggaggagggccggcagggtcagaccgagaagttccagtttgaactaactttagag
gaagatggcgagtccgacaccgaaaaggacagcggaagtcaagtggaagaagacactagc
tgcagtgactccaagactctctgcacccaggactcggagtccactgagatccccctggac
gaacaggtggaggaggaagccgtcggggaagaggaggagagccagcctgaagcctgcgca
gcagaggaccgttctcccgacacgtaa
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