Equus caballus (horse): 100052316
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Entry
100052316 CDS
T01058
Symbol
GART
Name
(RefSeq) trifunctional purine biosynthetic protein adenosine-3
KO
K11787
phosphoribosylamine--glycine ligase / phosphoribosylglycinamide formyltransferase / phosphoribosylformylglycinamidine cyclo-ligase [EC:
6.3.4.13
2.1.2.2
6.3.3.1
]
Organism
ecb
Equus caballus (horse)
Pathway
ecb00230
Purine metabolism
ecb00670
One carbon pool by folate
ecb01100
Metabolic pathways
ecb01523
Antifolate resistance
Module
ecb_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
ecb00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
100052316 (GART)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
100052316 (GART)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
100052316 (GART)
Enzymes [BR:
ecb01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.2 phosphoribosylglycinamide formyltransferase 1
100052316 (GART)
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.3 Cyclo-ligases
6.3.3.1 phosphoribosylformylglycinamidine cyclo-ligase
100052316 (GART)
6.3.4 Other carbon-nitrogen ligases
6.3.4.13 phosphoribosylamine---glycine ligase
100052316 (GART)
BRITE hierarchy
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
GARS_A
Formyl_trans_N
AIRS_C
GARS_N
GARS_C
AIRS
ATP-grasp
ATP-grasp_3
CPSase_L_D2
ATP-grasp_2
Dala_Dala_lig_C
ATP-grasp_4
RimK
ATP-grasp_5
DUF3104
Motif
Other DBs
NCBI-GeneID:
100052316
NCBI-ProteinID:
XP_001497971
Ensembl:
ENSECAG00000019797
VGNC:
18249
LinkDB
All DBs
Position
26:complement(31409407..31436216)
Genome browser
AA seq
1010 aa
AA seq
DB search
MAARVLVIGNGGREHTLAWKLAQSSHVKKVLVAPGNAGTACSEKISNTAVSISDHAALAQ
FCKDEKIEFVVVGPEAPLAAGIVGNLTSAGVRCFGPTAEAAQLESSKRFAKEFMDRHGIP
TAQWRAFTKPEEACSFIMSADFPALVVKASGLAAGKGVIVAESKEEACRAVQEIMQDKAF
GAAGETIVVEELLEGEEVSCLCFTDGRTVAPMPPAQDHKRLLEGDRGPNTGGMGAYCPAP
QVSKDLLLKIKNIILQKTVEGMQQEGMPYTGVLYAGIMLTKDGPKVLEFNCRFGDPECQV
ILPLLKSDLYEVIQSTLDGLLCTSPPVWLENHTAVTVVMASKGYPGDYTKGVEITGFPEA
QALGLEVFQAGTALKDGRVVTNGGRVLSVTAIRENLISALEEAKKGLAAIKFEGAIYRKD
IGFRAIAFLQQPRGLTYKESGVDIAAGNMLVQKIKPLAKATSRPGCDVDLGGFAGLFDLK
AAGFKDPLLACGTDGVGTKLKIAQQCNKHDTIGQDLVAMCVNDILAQGAEPLFFLDYFSC
GKLDLHTTEAVVAGIAEACGKAGCALLGGETAEMPDMYPPGEYDLAGFAVGAMERDQKLP
HLERIAEGDVVIGIASSGLHSNGFSLVRKIVAKSSLQYSSPAPDGCGEQTLGDLLLTPTR
IYSHSLLPVLRSGHVKAFAHITGGGLLENIPRVLPQKFGVDLDAQTWRIPRIFSWLQQEG
HLSEEEMARTFNCGIGAALIVSKDVTKQVLRDIQQHKEEAWVIGSVVACSEGSPRVKVKH
LIETMQINVSMLANGALKNHFSVQPKKARVAVLISGTGSNLQALIDSTREPSSSAHIVVV
ISNKAAVAGLDKAERAGIPTRVINHKLYKSRVEFDTAIDQVLEEFSTSIVCLAGFMRILS
GPFVRKWNGKMLNIHPSLLPSFKGSNAHEQVLDAGVTVTGCTVHFVAEDVDAGQIILQEA
VPVKRGDTVATLSERVKLAEHKIFPAALQLVASGTIQLGENGKICWVKEE
NT seq
3033 nt
NT seq
+upstream
nt +downstream
nt
atggcagcccgagtactagtaattggcaatggaggaagggaacatacgctggcctggaaa
cttgcacagtctagtcatgtcaaaaaagtgttggttgctccaggaaatgcaggcactgcc
tgctctgaaaagatatcaaatactgccgtctccatcagtgatcacgctgcccttgctcag
ttctgcaaagatgagaaaattgaattcgtagttgttggaccagaggcacctctggctgca
ggaattgttgggaacctgacgtctgcaggagtgcgatgctttggtcccacagcagaagca
gctcagttagagtcgagcaaaagatttgccaaagaatttatggaccgacatggaatccca
actgcgcagtggagagctttcaccaaacctgaagaggcctgcagcttcatcatgagtgca
gacttccctgctttggttgtgaaggccagtgggcttgccgccgggaaaggagtgattgtt
gcagagagcaaagaagaggcctgcagagctgtccaggagatcatgcaggataaagctttt
ggagcagctggagaaacaattgtcgttgaagaacttcttgagggagaagaggtgtcttgt
ctgtgcttcactgatggaaggactgtggcccccatgcccccagcacaggaccataagcga
ctgctcgagggagatcgcggccccaacacagggggaatgggagcctactgcccagcacct
caggtttctaaggatttgttgctaaaaattaaaaacatcattcttcagaagacggtggag
ggcatgcagcaggagggtatgccatacacaggtgttctctatgctggtataatgctgacc
aaggatggcccaaaagttctggagtttaattgccgctttggtgatccagagtgccaagtg
atcctcccacttcttaaaagtgacctttatgaagtgattcagtctaccttagacggcctg
ctctgcacatctcctcctgtttggcttgaaaaccacaccgccgtaactgttgtcatggca
agtaaaggttatccaggagactataccaagggtgtggagataacagggtttcctgaggct
caagctttaggactggaggtgttccaagcaggcactgccctgaaagacggcagagtggtg
actaacgggggtagagtcctttccgtaacagccatccgggaaaatctcatctcggccctt
gaagaagccaagaaaggactagctgctatcaagtttgagggagccatttacaggaaggac
atcggcttccgtgccatagctttcctccagcagcccaggggcctgacttacaaggaatct
ggggtagacattgcagctggaaatatgctggtccagaaaatcaaacctttagcaaaagcc
acctccagaccaggctgtgacgttgatcttggaggttttgctggtctttttgatttgaaa
gcagccggtttcaaagatcctcttctggcctgtggaacagatggcgttggaactaaactg
aagatcgcccagcagtgcaataaacacgacaccattggtcaggatttggtcgccatgtgt
gtaaatgatattctggcacaaggagcagagcccctcttcttcctcgattacttttcctgt
ggaaaacttgacctccacacgaccgaagctgttgttgctggaatcgcagaagcttgtgga
aaagctggatgtgctctccttggaggtgaaacagcagaaatgcctgacatgtatcctcct
ggagagtacgacctagccggttttgccgtcggcgccatggagcgggatcagaaactccct
cacctggaaagaatcgctgaaggggatgttgttatcggaatagcttcatctggtcttcat
agcaatggatttagcctcgtgaggaaaattgtagcgaaatcttccctccagtactcctct
ccagcacctgatggctgtggggagcagaccttaggagacttacttctaactccaaccaga
atctacagccattcactgttacctgtcctacgttcaggacacgtcaaggcttttgcccat
attactggtggaggattgctagaaaacatccccagagtcctccctcagaaatttggggtg
gatttagatgcccagacctggaggatccccaggatcttctcgtggttacagcaggaagga
cacctctctgaagaagagatggccagaacatttaactgtggaattggcgctgcccttata
gtatcaaaggatgtgacaaagcaggttctgagggatattcagcagcacaaggaagaggcc
tgggtgattggcagcgtagttgcgtgttctgaaggttctcctcgtgtgaaagtcaagcat
ctgattgaaaccatgcaaataaatgtatcgatgttggcaaatggtgccctgaaaaatcat
ttctctgtccaaccaaaaaaggcaagagtggctgtcttaatatctggaacaggatcaaac
ctccaagctctcatagacagtactcgagagccaagtagctctgcacacattgttgttgtt
atctccaacaaagctgcagtggctggattagataaagcggaaagagctggaattcccacg
agagtaattaatcataaattatacaaaagtcgtgtagaatttgacactgcaattgaccaa
gtccttgaagagttctccaccagcatagtctgtcttgcaggattcatgagaattttatct
ggcccctttgtccgaaagtggaatgggaaaatgctcaacatacacccatccttgctcccc
tcttttaagggttcaaatgcccatgagcaagtcctggacgctggagtcacagtcactggg
tgcaccgtgcactttgtagctgaagatgtagatgctggacaaattattttacaagaagct
gttccagtgaagaggggtgacactgttgcaactctgtctgaaagagtgaaattggcagaa
cataaaatatttcccgcagccctccagctggtggccagtggaaccatacagcttggggaa
aatggcaagatctgttgggtcaaagaggaatga
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