Equus caballus (horse): 100052619
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Entry
100052619 CDS
T01058
Symbol
PDE2A
Name
(RefSeq) cGMP-dependent 3',5'-cyclic phosphodiesterase isoform X1
KO
K18283
cGMP-dependent 3',5'-cyclic phosphodiesterase [EC:
3.1.4.17
]
Organism
ecb
Equus caballus (horse)
Pathway
ecb00230
Purine metabolism
ecb01100
Metabolic pathways
ecb04022
cGMP-PKG signaling pathway
ecb04740
Olfactory transduction
ecb04925
Aldosterone synthesis and secretion
ecb05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
ecb00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
100052619 (PDE2A)
09130 Environmental Information Processing
09132 Signal transduction
04022 cGMP-PKG signaling pathway
100052619 (PDE2A)
09150 Organismal Systems
09152 Endocrine system
04925 Aldosterone synthesis and secretion
100052619 (PDE2A)
09157 Sensory system
04740 Olfactory transduction
100052619 (PDE2A)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
100052619 (PDE2A)
Enzymes [BR:
ecb01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.17 3',5'-cyclic-nucleotide phosphodiesterase
100052619 (PDE2A)
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Paralog
Gene cluster
GFIT
Motif
Pfam:
PDEase_I
GAF
GAF_2
GAF_3
HD-CE
Motif
Other DBs
NCBI-GeneID:
100052619
NCBI-ProteinID:
XP_001499110
Ensembl:
ENSECAG00000018696
VGNC:
21242
UniProt:
F6UGJ6
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Position
7:73205460..73295532
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AA seq
941 aa
AA seq
DB search
MGQACGHSILCRSQQYPAARPAEPRGQQVFLKPDEPPPPQPCADSLQDALLNLGSVIDIA
GFRRAVKEALSAVLPRVETVYTYLLDTESRLVCEDPPHELPQEGKVREAVISRKRLSCNG
LGPSDHPGKPLARLVAPLAPDTQVLVIPLVDKEAGAVAAVILVHCGQLSDSDEWNLQAVE
KHTLVALRRVQALQQRGPSADPEAVQKPPAGAAGDQEGGISYTDQDRKILQLCGELYDLD
ASSLQLKVLQYLQQETRASRCCLLLVSEDNLQLSCKVIGDKVLEEELSFPLTTGRLGQVV
EDKKSIQLKDLTPEDVQQLQSMLGCELQAMLCVPVISRATDQVVALACAFNKLEGDLFTD
EDEHVIQHCFHYTSTVLTSTLAFQKEQKLKCECQALLQVAKNLFTHLDDVSVLLQEIITE
ARNLSNAEICSVFLLDQNELVAKVFDGGVVEDESYEIRIPADQGIAGHVATTGQILNIPD
AYAHPLFYRGVDDSTGFRTRNILCFPIKNENQEVIGVAELVNKINGPWFSKFDEDLATAF
SIYCGISIAHSLLYKKVNEAQYRSHLANEMMMYHMKVSDDEYTKLLHDGIQPVAAIDSNF
SSFTYTPRSLPEDDTSMAILSMLQDMNFINNYKIDCPTLARFCLMVKKGYRDPPYHNWMH
AFSVSHFCYLLCKNLELTNYLEDIEIFALFISCMCHDLDHRGTNNSFQVASKSVLAALYS
SEGSVMERHHFAQAIAILNTHGCNIFDHFSRKDYQRMLDLMRDIILATDLAHHLRIFKDL
QKMAEVGYDRTNKQHHSLLLCLLMTSCDLSDQTKGWKTTRKIAELIYKEFFSQGDLEKAM
GNRPMEMMDREKAYIPELQISFMEHIAMPIYKLLQDLFPKAAELYERVASNREHWTKVSH
KFTIRGLPSNNSLDFLDEEYEVPQLDGTRGPINGCCSLDAE
NT seq
2826 nt
NT seq
+upstream
nt +downstream
nt
atggggcaggcatgcggccactccatcctctgcaggagccagcagtacccggcagcgcga
ccggctgagccgcggggccagcaggtcttcctcaagccggacgagccgccgccgccgcag
ccatgcgccgacagcctgcaggatgctttgctgaacctgggctccgtcatcgacattgcg
ggctttcgacgggctgtcaaggaggccctctccgccgtgctccccagagtggagaccgtc
tacacctacctgctggacacggagtcccggctggtgtgtgaggacccgccccacgagctg
ccccaggagggaaaagtccgagaggctgtgatctcccggaagcggctgagctgcaatgga
ctcggcccctcggaccacccggggaaacccttggccaggctggtggctccactggcccct
gacacccaagtgctggtcataccgctcgtggacaaggaggccggggctgtggcagctgtc
atcttggtacactgtggccagctgagtgacagtgatgagtggaacctgcaagccgtggag
aagcataccctggtggccctgcggagggtgcaggccctgcagcagcgcgggcccagcgcg
gaccccgaagccgtccagaaaccccccgcgggggcggcaggagaccaggaaggcgggatt
tcgtacacggaccaggaccggaagatcctgcaactctgcggggaactctacgacctggat
gcctcttccctgcagctcaaagtcctccaatacctgcagcaggagacccgggcatcccgc
tgctgcctcctgctggtgtccgaggacaatctccagctttcctgtaaggtcattggagat
aaagtgctggaggaagagctcagctttccgttgacgacaggacgcctgggccaggtggtg
gaagacaagaagtctatccagctgaaagatctcacccctgaggatgtgcaacagctgcaa
agcatgttgggctgcgagttgcaggccatgctctgtgtccctgtcatcagccgggccact
gatcaggtggtggctttggcctgcgccttcaacaagctcgaaggagacttgttcacggac
gaggacgagcatgtgatccagcactgcttccactacaccagcaccgtgctcaccagcacc
ctcgccttccagaaggagcagaagctcaagtgtgagtgccaggctcttctccaagtggca
aagaacctcttcactcacctggatgacgtttctgtcctgctccaggagatcatcaccgag
gccagaaacctcagcaatgctgagatctgctccgtgttcctgctggatcagaatgaactg
gtggccaaggtgttcgatgggggcgtggtggaggacgagagctatgagatccgcatcccg
gccgaccagggcatcgcaggccacgtggcaaccacgggccagatcctgaacatccccgac
gcgtacgcgcacccgcttttctaccgtggcgtagacgacagcaccggcttccgtacgcgc
aacatcctctgcttccccatcaagaacgagaaccaggaggtcatcggtgtggccgagctg
gtgaacaagatcaacggaccatggttcagcaagttcgacgaggacctggcgacagccttc
tccatttactgcggcatcagcatcgcccattccctcctgtacaagaaagtgaatgaggcc
cagtatcgcagccacctggccaacgagatgatgatgtaccacatgaaggtctctgatgat
gaatacaccaaacttctccatgacgggatccagcccgtggccgccattgactccaacttt
tccagttttacctacacccctcgctctctgcccgaggatgacacctccatggccatcctg
agcatgttgcaggacatgaatttcatcaacaactacaaaatcgactgccccacgctggcc
cggttctgtctgatggtgaagaagggctaccgggaccccccctaccacaactggatgcac
gccttctctgtctcccacttctgctacctgctctgcaagaacctggagctcaccaactac
ctcgaggacatcgagatctttgccttgtttatttcctgcatgtgtcacgacctggaccac
agaggcacaaacaactccttccaggtggcctcgaaatctgtgctggccgcgctctacagc
tccgagggctctgtcatggagaggcatcactttgctcaggccatcgccatcctcaacacg
catggttgcaacatcttcgaccacttctcccggaaggactatcagcgcatgctggacctg
atgcgggacatcatcttggccacggacctggctcaccacctccgcatcttcaaggacctc
cagaagatggctgaagtgggctatgaccgaaccaacaagcagcaccacagcctcctcctc
tgcctccttatgacctcctgtgacctctctgaccagaccaagggctggaagaccacgagg
aagatcgcagagctgatctacaaagagttcttctcccagggagacttggagaaggccatg
ggcaacaggccaatggagatgatggaccgtgagaaagcctacatccccgagctgcagatc
agcttcatggagcacatcgcaatgcccatctacaagctgctgcaggacctgttccccaag
gcagcagagctgtacgagcgcgtggcctctaaccgtgagcactggaccaaggtgtcccac
aagttcaccatccgcggcctccccagcaacaactcgctggacttcctggacgaggagtac
gaggtgcctcagctggatggcactcggggccccatcaatggctgctgcagcctcgatgct
gagtga
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