KEGG   Equus caballus (horse): 100052709
Entry
100052709         CDS       T01058                                 
Symbol
EIF2S1
Name
(RefSeq) eukaryotic translation initiation factor 2 subunit 1
  KO
K03237  translation initiation factor 2 subunit 1
Organism
ecb  Equus caballus (horse)
Pathway
ecb04137  Mitophagy - animal
ecb04140  Autophagy - animal
ecb04141  Protein processing in endoplasmic reticulum
ecb04210  Apoptosis
ecb04932  Non-alcoholic fatty liver disease
ecb05010  Alzheimer disease
ecb05012  Parkinson disease
ecb05014  Amyotrophic lateral sclerosis
ecb05020  Prion disease
ecb05022  Pathways of neurodegeneration - multiple diseases
ecb05160  Hepatitis C
ecb05162  Measles
ecb05164  Influenza A
ecb05168  Herpes simplex virus 1 infection
ecb05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:ecb00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    100052709 (EIF2S1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    100052709 (EIF2S1)
   04137 Mitophagy - animal
    100052709 (EIF2S1)
  09143 Cell growth and death
   04210 Apoptosis
    100052709 (EIF2S1)
 09160 Human Diseases
  09172 Infectious disease: viral
   05160 Hepatitis C
    100052709 (EIF2S1)
   05164 Influenza A
    100052709 (EIF2S1)
   05162 Measles
    100052709 (EIF2S1)
   05168 Herpes simplex virus 1 infection
    100052709 (EIF2S1)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    100052709 (EIF2S1)
   05012 Parkinson disease
    100052709 (EIF2S1)
   05014 Amyotrophic lateral sclerosis
    100052709 (EIF2S1)
   05020 Prion disease
    100052709 (EIF2S1)
   05022 Pathways of neurodegeneration - multiple diseases
    100052709 (EIF2S1)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    100052709 (EIF2S1)
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease
    100052709 (EIF2S1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03012 Translation factors [BR:ecb03012]
    100052709 (EIF2S1)
   04131 Membrane trafficking [BR:ecb04131]
    100052709 (EIF2S1)
Translation factors [BR:ecb03012]
 Eukaryotic type
  Initiation factors
   eIF-2
    100052709 (EIF2S1)
Membrane trafficking [BR:ecb04131]
 Autophagy
  ER-phagy
   ER stress-related proteins
    100052709 (EIF2S1)
SSDB
Motif
Pfam: EIF_2_alpha S1
Other DBs
NCBI-GeneID: 100052709
NCBI-ProteinID: XP_001499818
Ensembl: ENSECAG00000018424
VGNC: 17487
UniProt: F7CTS5
LinkDB
Position
24:13576175..13595322
AA seq 315 aa
MPGLSCRFYQHKFPEVEDVVMVNVRSIAEMGAYVSLLEYNNIEGMILLSELSRRRIRSIN
KLIRIGRNECVVVIRVDKEKGYIDLSKRRVSPEEAIKCEDKFTKSKTVYSILRHVAEVLE
YTKDEQLESLFQRTAWVFDDKYKRPGYGAYDAFKHAVSDPSILDSLDLNEDEREVLINNI
NRRLTPQAVKIRADIEVACYGYEGIDAVKEALRAGLNCSTETMPIKINLIAPPRYVMTTT
TLERTEGLSVLNQAMAVIKEKIEEKRGVFNVQMEPKVVTDTDETELARQLERLERENAEV
DGDDDAEEMEAKTED
NT seq 948 nt   +upstreamnt  +downstreamnt
atgccgggtctaagttgtagattttatcaacacaaatttcctgaggtggaagacgtagtg
atggtgaatgtaaggtccattgctgaaatgggggcttacgtcagcttgctagagtacaac
aatattgaaggcatgattcttcttagtgagttgtccagaaggcgtatccgttctataaac
aaactcatccgaattggcagaaatgaatgtgtggttgtcattagagtggacaaagaaaaa
ggatacattgatttgtcaaaaagaagagtttctccagaggaagcaatcaaatgtgaagat
aaattcaccaaatccaaaactgtttacagcattcttcgtcatgttgctgaggtgttagag
tacaccaaggatgagcagctggaaagcctgttccagaggactgcctgggtctttgatgac
aagtacaagagacccggatacggtgcctatgatgcgtttaagcatgcagtctcggacccc
tctattttggacagtttagatttgaatgaagatgaacgggaagtactcattaacaatatt
aataggcgtttgaccccacaggcagtcaaaattcgagcagatattgaagtggcttgttat
ggttatgaaggcattgatgccgtaaaagaagccctgagagcaggtttgaattgttctaca
gaaactatgcccatcaagattaatctaatagctcctcctcggtatgtgatgactacaaca
accctggagagaacagaaggtctctctgtcctcaatcaagctatggctgttatcaaagaa
aagattgaggaaaagaggggtgtcttcaatgtgcaaatggagcccaaagtggttacagat
acagatgagaccgagcttgcaaggcaactggagaggcttgagagagaaaatgcagaagtg
gatggagatgatgatgcagaagaaatggaagccaaaactgaagattaa

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