Equus caballus (horse): 100053606
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Entry
100053606 CDS
T01058
Symbol
PDHA2
Name
(RefSeq) pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
ecb
Equus caballus (horse)
Pathway
ecb00010
Glycolysis / Gluconeogenesis
ecb00020
Citrate cycle (TCA cycle)
ecb00620
Pyruvate metabolism
ecb00785
Lipoic acid metabolism
ecb01100
Metabolic pathways
ecb01200
Carbon metabolism
ecb01210
2-Oxocarboxylic acid metabolism
ecb04066
HIF-1 signaling pathway
ecb04922
Glucagon signaling pathway
ecb05230
Central carbon metabolism in cancer
ecb05415
Diabetic cardiomyopathy
Module
ecb_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
ecb00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
100053606 (PDHA2)
00020 Citrate cycle (TCA cycle)
100053606 (PDHA2)
00620 Pyruvate metabolism
100053606 (PDHA2)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
100053606 (PDHA2)
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
100053606 (PDHA2)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
100053606 (PDHA2)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
100053606 (PDHA2)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
100053606 (PDHA2)
Enzymes [BR:
ecb01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
100053606 (PDHA2)
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Gene cluster
GFIT
Motif
Pfam:
E1_dh
DXP_synthase_N
TPP_enzyme_C
Motif
Other DBs
NCBI-GeneID:
100053606
NCBI-ProteinID:
XP_014594065
Ensembl:
ENSECAG00000001158
UniProt:
A0A5F5PZG6
LinkDB
All DBs
Position
3:complement(43809678..43811123)
Genome browser
AA seq
439 aa
AA seq
DB search
MQRHDVASVTNAPIVAPRAFSPRDTQKVGGVALAVWVVGGCGCPVLHSMKKMLAAAVSRV
LGGGAQKPASRVLVASCNYSNDATFEIKKCDLHRLEEGPPVTAVLTREDGLQYYRMMQTV
RRMELKADQLYKQKFIRGFCHLCDGQEACYVGLKAGANPSDHAITAYRAHGLCYAYGLSV
QSILAELTGRRGGCAKGKGGSMHMYGRNFYGGNGIVGAQVPLGAGVALACKYKGSNEVCL
TLYGDGAANQGQIFEAYNMAALWKLPCIFICENNRYGMGTAIERASASTDYYKRVNFIPG
LRVDGMDVLCVREAAKFAADYCRSGKGPIVMELQTYRYHGHSMSDPGISYRTREEIQNIR
SKSDPIMLLKDKMLNNKLSSIEELKEIDVGVRKEIDDAAQFATTDPEPPLEELGHHVYNN
NLPFEVRGTNQWIKFKSIS
NT seq
1320 nt
NT seq
+upstream
nt +downstream
nt
atgcagcggcatgacgtggcctctgtcaccaacgcccccattgtggcgccgcgtgcgttc
agcccgagggacacgcagaaggtcggcggggtcgccctggcagtttgggttgttggcggt
tgcggctgccctgtacttcactccatgaagaagatgctcgctgccgccgtctcccgcgtg
ttgggaggaggggcccagaagcccgctagcagagtgctggtggcgtcctgtaactattca
aatgatgccacatttgaaattaagaaatgtgatcttcatcggttggaagagggtccgcct
gtcacagcagtgctcacccgggaggatgggctccagtactacaggatgatgcagactgtt
cgccgaatggaattgaaggcagatcagctgtataaacagaaatttattcgtggtttctgc
cacttgtgtgatggtcaggaagcttgttatgtgggccttaaggccggggcaaatccctcc
gatcacgcgatcacagcctatcgggctcacggcttatgctacgcttacggactttctgtg
caatcaattcttgcagagctgactggacgaagaggaggttgtgctaaaggaaaaggagga
tcgatgcatatgtacggcaggaacttctatgggggcaacggcattgttggtgctcaggta
cccctgggagctggtgttgctctggcctgtaaatataagggaagcaatgaggtctgtttg
actctgtatggggatggtgctgctaatcagggtcagatatttgaagcttataatatggca
gctttgtggaaattaccttgtattttcatctgtgagaataatcgctatggaatgggaaca
gctattgagagagcatcagccagcactgactactacaagagagttaattttatccctgga
ctaagggtagatggaatggatgtcctatgtgttcgagaggcagctaagtttgcagctgac
tactgtagatctggaaagggacccatagtgatggagctgcagacataccgttatcatggg
catagtatgagtgatcctggaatcagttatcgtaccagagaggaaattcagaacataaga
agtaagagtgatcccattatgcttctcaaagataaaatgttgaacaacaagctttccagt
attgaagaattgaaagaaattgatgttggagtgaggaaagaaattgatgatgcagcccag
tttgctacaactgatccagagccaccactggaagaattaggccatcatgtctacaacaat
aatctaccttttgaagttcgtggtacaaatcagtggatcaagtttaagtccatcagttaa
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