Equus caballus (horse): 100054229
Help
Entry
100054229 CDS
T01058
Symbol
TOP2A
Name
(RefSeq) DNA topoisomerase 2-alpha isoform X1
KO
K03164
DNA topoisomerase II [EC:
5.6.2.2
]
Organism
ecb
Equus caballus (horse)
Pathway
ecb01524
Platinum drug resistance
Brite
KEGG Orthology (KO) [BR:
ecb00001
]
09160 Human Diseases
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
100054229 (TOP2A)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:
ecb03032
]
100054229 (TOP2A)
03036 Chromosome and associated proteins [BR:
ecb03036
]
100054229 (TOP2A)
Enzymes [BR:
ecb01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.2 DNA topoisomerase (ATP-hydrolysing)
100054229 (TOP2A)
DNA replication proteins [BR:
ecb03032
]
Eukaryotic type
DNA Topoisomerases
100054229 (TOP2A)
Chromosome and associated proteins [BR:
ecb03036
]
Eukaryotic type
Chromosome condensation proteins
Other regulators of chromosome condensation
100054229 (TOP2A)
Centrosome formation proteins
Centriole proteins
100054229 (TOP2A)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
DNA_topoisoIV
TOPRIM_C
DNA_gyraseB
DTHCT
HATPase_c
Toprim
Microp_apicomplexa_20
Motif
Other DBs
NCBI-GeneID:
100054229
NCBI-ProteinID:
XP_023508319
Ensembl:
ENSECAG00000013053
VGNC:
50516
LinkDB
All DBs
Position
11:22242536..22266866
Genome browser
AA seq
1530 aa
AA seq
DB search
MDVSPLQPINENMQINKAKKNEDAKKRLSVERIYQKKTQLEHILLRPDTYIGSVELVTQQ
MWVYDEDVGINYREVTFVPGLYKIFDEILVNAADNKQRDPKMSCIRVTIDPENNLISIWN
NGKGIPVVEHKVEKMYVPALIFGQLLTSSNYDDDEKKVTGGRNGYGAKLCNIFSTKFTVE
TASREYKKMFKQTWMDNMGRAGEMELKPFNGEDYTCITFHPDLSKFKMQSLDKDIVALMV
RRAYDIAGSTKDVKVFLNGNKLPVKGFRSYVDMYLKDKVDETGNPLKIIHEQVNHRWEVC
LTMSEKGFQQISFVNSIATSKGGRHVDYVADQIVTKLVDVVKKKNKGGVAVKAHQVKNHM
WIFVNALIENPTFDSQTKENMTLQAKNFGSTCQLSEKFIKAAIGCGIVESILNWVKFKAQ
VQLNKKCSAVKHNRIKGIPKLDDANDAGGRNSTECTLILTEGDSAKTLAVSGLGVVGRDK
YGVFPLRGKILNVREASHKQIMENAEINNIIKIVGLQYKKNYEDEDSLKTLRYGKIMIMT
DQDQDGSHIKGLLINFIHHNWPSLLRHRFLEEFITPIVKVSKNKQEMAFYSLPEFEEWKS
STPNHKKWKVKYYKGLGTSTSKEAKEYFADMKRHRIQFKYSGPEDDAAISLAFSKKQIDD
RKEWLTHFMEDRRQRKLLGLPEDYLYGQTTTYLTYNDFINKELILFSNSDNERSIPSMVD
GLKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSSYHHGEMSLMMTIINLAQNFVGSNN
LNLLQPIGQFGTRLHGGKDSASPRYIFTMLSPLARLLFPPKDDHTLKFLYDDNQRVEPEW
YIPIIPMVLVNGAEGIGTGWSCKIPNFDVREIVNNIRRLMDGEEPLPMLPSYKNFKGTIE
ELAPNQYVISGEVAILNSTTIEISELPIRTWTQTYKEQVLEPMLNGTEKTPPLITDYREY
HTDTTVKFVVKMTEEKLAEAERVGLHKVFKLQTSLTCNSMVLFDHVGCLKKYDTVLDILR
DFFELRLKYYGLRKEWLLGMLGAESAKLNNQARFILEKIDGKIIIENKPKKELIKVLIQR
GYDSDPVKAWKEAQQKVPDEEENEESDSEKETEKSGSVTDSGPTFNYLLDMPLWYLTKEK
KDELCKLRNEKEQELETLKRKSPSDLWKEDLAAFIEELEAVEAKEKQDEQVGLPGKGGKA
KGKKTQRAEVLPSPSGKRVIPRVTIEMKAEAEKKFKKKIKSENTEGSPQEDGTEVEGLKQ
RLEKKQKRQPDTKTKKQITLPFKPVKGKKRNPWSDSESDMSSNESNFDVPPRETEPRRAA
TKTKFTMDLDSDEPFSDFDEKTQEEDFVPSDSSLPKTKSSLKHANKELKTQKSAVSVTDL
DADDAKDSVPLSPSSSAADFPAETEIINPISKKKVTVKKIAAKSQSSTSTTGTKKPATKR
VKKDPGLNSDVSQKPDMPKTKNPRKRKPSTSDDSDSNFEKMISKAVTNKKSKENDDFHLD
LDSTVAPRAKSGRARKPIKYLEESDEDDLF
NT seq
4593 nt
NT seq
+upstream
nt +downstream
nt
atggacgtgtcaccgctgcagcccataaatgaaaatatgcaaatcaacaaagcaaagaaa
aatgaagatgcgaagaaaagactctccgttgaaagaatctatcaaaagaaaacgcagttg
gaacatattttgctccgcccagacacctacattggttccgtggaattagtgacccagcaa
atgtgggtttacgatgaagacgttggcattaactatagggaagtcacttttgttcctggt
ttatacaaaatctttgatgagattctagttaatgctgcagacaacaaacaaagggaccca
aaaatgtcttgtattagagtcacaattgacccggaaaacaatttaattagcatatggaat
aatggaaaaggtattcctgttgttgaacacaaagttgagaagatgtatgtcccagctctc
atctttggacagctcctaacttctagtaactatgatgatgatgaaaagaaagtaacaggt
ggtcgaaatggctatggagccaaattgtgtaacatatttagtaccaaatttactgtggaa
acagccagtagagaatacaagaaaatgttcaaacagacatggatggataatatggggaga
gctggtgagatggaactcaagccctttaacggagaagattatacgtgtattaccttccac
cctgatttgtctaagtttaaaatgcaaagcctagacaaagatattgttgcactaatggtt
agacgagcatatgatattgctggatccactaaagatgtcaaagtctttcttaacggaaat
aagctgccagtaaaaggattccgtagctatgtggacatgtatttgaaggataaggtagat
gaaactggcaatccattgaaaattatacatgaacaagtaaaccacaggtgggaagtgtgt
ttaacaatgagtgaaaaaggctttcagcaaattagctttgtcaacagcattgctacttca
aagggtggcaggcatgttgattacgtagctgatcagattgtcactaagcttgtcgatgtt
gtgaagaagaagaacaagggtggtgttgcagtaaaagcacatcaggtgaaaaatcacatg
tggatttttgtgaatgccttaattgaaaacccaacctttgactctcagacaaaagaaaac
atgactttacaagccaagaactttggatcaacatgccaattaagtgaaaaattcatcaaa
gctgcaattggctgtggtatcgtagaaagcatactaaactgggtgaagtttaaggcccaa
gtacagttaaacaagaagtgttcagctgtaaaacataacagaatcaagggaattcccaaa
cttgatgatgccaatgatgcagggggccgaaactcaactgagtgtacacttattctgact
gagggagactcagctaaaactttggctgtttcaggccttggtgtggttggaagagacaaa
tatggggttttccctcttagaggaaaaatactcaatgttcgagaagcttctcataaacag
ataatggaaaatgccgaaattaacaatatcatcaagattgtgggtcttcaatacaagaaa
aactatgaagatgaagattcattgaagactcttcgttatgggaagataatgattatgaca
gatcaggaccaagatggttcccacatcaaaggcttgctgattaattttatccatcacaat
tggccctctcttctgcgacatcgttttctggaggaatttatcactcccattgtaaaggtg
tctaaaaacaagcaagaaatggcattctatagcctccctgaatttgaagaatggaagagt
tctactccaaatcataaaaaatggaaagtcaagtattacaaaggtttgggcaccagcaca
tcaaaagaagctaaagaatattttgcagatatgaaaagacatcgtatccaattcaaatat
tctggtcctgaagatgatgctgcaatcagcctggcctttagcaaaaaacagatagatgat
cgaaaggaatggttaactcatttcatggaggatagaaggcaacgaaagttacttggcctt
cctgaggattacttatatgggcaaactaccacatatctgacatacaatgacttcataaac
aaggaacttatcctgttctcaaattctgataatgagagatctatcccatctatggtggat
ggtttgaaaccaggtcagagaaaggttttgtttacatgtttcaaacggaatgacaagcga
gaggtgaaggttgcccagttagctgggtcagtagctgagatgtcctcttatcatcatggt
gagatgtcgctaatgatgaccattatcaatttggctcagaattttgtgggtagcaataat
ttgaacctcttgcagcctattggtcagtttggtaccaggctgcatggtggcaaggattct
gctagtcctcgatacatcttcacaatgctcagcccgttggctcggttgctatttccacca
aaagatgatcacacattaaagtttttatatgatgacaaccaacgtgttgagcctgaatgg
tacattcctattatacccatggtgctggtaaatggcgcggaaggaatcggtactggatgg
tcctgcaaaatccctaactttgatgttcgtgaaattgtgaataacatcagacgtttgatg
gatggagaagaacctttgccaatgcttccgagttataagaacttcaagggaactattgaa
gagctggctccaaatcaatatgtgattagtggtgaagtggctattcttaattccacaacc
attgaaatctcagagcttcccatcagaacgtggacccagacttataaagaacaggttcta
gaacccatgttgaatggcactgagaagacaccccctctcataacagattatagggaatac
catacagataccactgtaaagtttgttgtgaagatgactgaagaaaaactggcagaagca
gaaagagttggactacacaaagtcttcaaactccagactagtctcacatgcaactctatg
gtgctctttgaccacgtaggctgtttaaagaagtacgacacagtgttggatattctaaga
gacttctttgaactcaggcttaaatattatggattaagaaaagaatggcttctaggaatg
cttggcgctgaatctgctaaactgaacaatcaggctcgctttatcttagagaaaatagat
ggcaaaataatcattgaaaataagcctaagaaagaattgattaaagttctgattcagagg
ggatatgattcggatcctgtgaaggcttggaaagaagcccagcaaaaggttccagatgaa
gaagaaaatgaagagagtgacagtgaaaaggaaactgaaaagagtggttctgtaacagat
tctggaccaaccttcaactaccttcttgatatgcctctttggtatctaactaaggaaaag
aaagatgaattgtgcaaactaagaaatgaaaaagagcaagagctggaaacattaaagaga
aagagtccatcagatttgtggaaagaagacttggctgcttttattgaagaattggaggct
gttgaggccaaagaaaaacaagatgaacaagtaggacttcctgggaaaggggggaaagca
aaggggaaaaaaacacaaagggctgaagttctgccttctccaagtggaaaaagagtcatc
ccccgagtgaccatagagatgaaagcagaggcagaaaagaaatttaaaaagaaaattaag
agtgaaaatactgaaggaagccctcaagaggacggtacagaggtagaaggcctaaaacaa
agattagagaagaaacagaaaagacaaccagataccaagacaaagaaacaaattacattg
ccatttaaaccagtcaaaggaaagaagagaaacccttggtctgattcagaatcagatatg
agcagtaatgaaagtaattttgatgtccctccacgagaaacagagccacggagagcagca
acaaaaaccaaattcacaatggatttggattcagatgaacctttctcagattttgatgaa
aaaactcaagaggaagattttgtcccatcagattctagtctacctaaaactaaaagttcc
ctaaaacatgctaacaaagaactgaagacacagaaaagtgcagtgtcagtaacagacctt
gatgctgatgatgccaaggacagtgtaccactttctccaagctcttcagctgctgatttc
ccagctgaaactgaaattataaatcctatttctaaaaagaaggtgacggtgaaaaaaata
gcagcaaaaagtcagtcttctacctccactaccggcaccaaaaagcctgcaacaaaaaga
gtcaagaaagatccaggtttgaattctgatgtctctcaaaagcctgatatgcccaaaacc
aaaaatccccgcaaaaggaagccatccacttctgatgattctgactctaattttgagaaa
atgatttctaaagcagtcacaaacaagaaatccaaggagaatgatgacttccatctggac
ttagactcaactgtggctcctcgtgcaaaatccggacgggcaaggaaacctataaagtac
ctcgaggaatcagatgaagatgatctgttttaa
DBGET
integrated database retrieval system
