Equus caballus (horse): 100054739
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Entry
100054739 CDS
T01058
Symbol
ERBB2
Name
(RefSeq) receptor tyrosine-protein kinase erbB-2 isoform X1
KO
K05083
receptor tyrosine-protein kinase erbB-2 [EC:
2.7.10.1
]
Organism
ecb
Equus caballus (horse)
Pathway
ecb01521
EGFR tyrosine kinase inhibitor resistance
ecb01522
Endocrine resistance
ecb01524
Platinum drug resistance
ecb04010
MAPK signaling pathway
ecb04012
ErbB signaling pathway
ecb04020
Calcium signaling pathway
ecb04066
HIF-1 signaling pathway
ecb04151
PI3K-Akt signaling pathway
ecb04510
Focal adhesion
ecb04520
Adherens junction
ecb04530
Tight junction
ecb05200
Pathways in cancer
ecb05205
Proteoglycans in cancer
ecb05206
MicroRNAs in cancer
ecb05212
Pancreatic cancer
ecb05213
Endometrial cancer
ecb05215
Prostate cancer
ecb05219
Bladder cancer
ecb05223
Non-small cell lung cancer
ecb05224
Breast cancer
ecb05226
Gastric cancer
ecb05230
Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
ecb00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
100054739 (ERBB2)
04012 ErbB signaling pathway
100054739 (ERBB2)
04066 HIF-1 signaling pathway
100054739 (ERBB2)
04020 Calcium signaling pathway
100054739 (ERBB2)
04151 PI3K-Akt signaling pathway
100054739 (ERBB2)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
100054739 (ERBB2)
04520 Adherens junction
100054739 (ERBB2)
04530 Tight junction
100054739 (ERBB2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
100054739 (ERBB2)
05206 MicroRNAs in cancer
100054739 (ERBB2)
05205 Proteoglycans in cancer
100054739 (ERBB2)
05230 Central carbon metabolism in cancer
100054739 (ERBB2)
09162 Cancer: specific types
05212 Pancreatic cancer
100054739 (ERBB2)
05226 Gastric cancer
100054739 (ERBB2)
05219 Bladder cancer
100054739 (ERBB2)
05215 Prostate cancer
100054739 (ERBB2)
05213 Endometrial cancer
100054739 (ERBB2)
05224 Breast cancer
100054739 (ERBB2)
05223 Non-small cell lung cancer
100054739 (ERBB2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
100054739 (ERBB2)
01524 Platinum drug resistance
100054739 (ERBB2)
01522 Endocrine resistance
100054739 (ERBB2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
ecb01001
]
100054739 (ERBB2)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
ecb04147
]
100054739 (ERBB2)
04090 CD molecules [BR:
ecb04090
]
100054739 (ERBB2)
Enzymes [BR:
ecb01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
100054739 (ERBB2)
Protein kinases [BR:
ecb01001
]
Receptor tyrosine kinases (RTK)
EGFR family [OT]
100054739 (ERBB2)
Exosome [BR:
ecb04147
]
Exosomal proteins
Exosomal proteins of breast cancer cells
100054739 (ERBB2)
CD molecules [BR:
ecb04090
]
Proteins
100054739 (ERBB2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
GF_recep_IV
Pkinase
Furin-like
TM_ErbB1
ABC1
Haspin_kinase
Kinase-like
Motif
Other DBs
NCBI-GeneID:
100054739
NCBI-ProteinID:
XP_001501155
Ensembl:
ENSECAG00000020409
VGNC:
17649
LinkDB
All DBs
Position
11:complement(22757485..22780506)
Genome browser
AA seq
1255 aa
AA seq
DB search
MELAAWCRWGLLLALLPPGAAGTQVCTGTDMKLRLPASPETHLDMLRHLYQGCQVVQGNL
ELTYLPASASLSFLQDIQEVQGYVLIAHNQVRQVPLQRLRIVRGTQLFEDNYALAVLDNG
DLLDNATSATGAVPGGLRELQLRSLTEILKGGVLIQRNPQLCHQDTILWEDIFHKNNQLT
LTLIDTNRSRACQPCSPACRPSHCWGESSEDCQNLTRTVCAGGCARCKGPRPTDCCHEQC
AAGCTGPKHSDCLACLHFNHSGICELHCPSLVIYNTDTFESMPNPEGRYTFGASCVTACP
YNYLSTDVGSCTLVCPLNNQEVTAEDGTQRCEKCSKPCARVCYGLGMEHLREVRAVTSAN
IQDFAGCKKIFGSLAFLPESFEGDPASNTAPLQPEQLRVFETLEEITGYLYISAWPDSLP
DLSVFQNLRVIRGRVLHDGAYSLTLQGLGISWLGLRSLQELGSGLALVHHNARLCFVHTV
PWAQLFRNPHQALLHSANRPEDECVGEGLACYPLCAHGHCWGPGPTQCVNCSQFLRGQEC
VEECRVLQGLPREYVKDRYCLPCHPECQPQNGSVTCFGSEADQCVACTHYKDPPFCVARC
PSGVKPDLSFMPIWKFPDEEGTCQPCPINCTHSCLDLDDRGCPAEQRASPVTSIIAAVVG
ILLVVVIGLVLGILIKRRRQKIRKYTMRRLLQETELVEPLTPSGAMPNQAQMRILKETEL
RKVKVLGSGAFGTVYKGIWIPDGENVKIPVAIKVLRENTSPKANKEILDEAYVMAGVGSP
YVSRLLGICLTSTVQLVTQLMPYGCLLDHVREHRGRLGSQDLLNWCVQIAKGMSYLEDVR
LVHRDLAARNVLVKSPNHVKITDFGLARLLDIDETEYHADGGKVPIKWMALESILRRRFT
HQSDVWSYGVTVWELMTFGAKPYDGIPAREIPDLLEKGERLPQPPICTIDVYMIMVKCWM
IDSECRPRFRELVAEFSRMARDPQRFVVIQNEDLGPASPLDSTFYRSLLEDDDMGDLVDA
EEYLVPQQGFFCPDPAPGAGGTAHRRHRSSSSRSGGGELTLGLEPSEEEPPKSPLAPSEG
AGSDVFDGDLGMGAAKGLQSLPQHDPSPLQRYSEDPTVPLPPETDGYVAPLSCSPQPEYV
NQPEVRPQPPSPLEGPLSPCRPDGATLERPKTLSPGKNGVVKDVFAFGGAVENPEYLAPR
SRAAPQPHPPPAFSPAFDNLYYWDQDPSERGSPPSTFEGTPTAENPEYLGLDVPV
NT seq
3768 nt
NT seq
+upstream
nt +downstream
nt
atggagctggcggcctggtgccgctgggggctcctcctcgccctcctgccccccggagcc
gcgggcacccaagtgtgcaccggcacagacatgaagctgcggctgccagccagtcctgag
acccacctggacatgctccgccacctctaccagggctgccaggtggtgcagggtaacctg
gagctcacctacctgccagccagcgccagcctctccttcctgcaggatatccaggaggtg
caaggctatgtgctcatcgctcacaaccaagtgagacaggtcccactgcagaggctgcga
atcgtgcgaggcacccagctctttgaggacaactacgccctggctgtgctggacaatgga
gacctgctggacaatgccacctctgctacaggggctgtcccaggagggctgcgggagcta
cagcttcgaagcctcacagagatcttgaagggaggggtcttgatccagcggaacccccag
ctctgccaccaggacacgattttgtgggaggacatcttccacaagaacaaccagctgacc
ctcacgctgatagacaccaaccgctcacgggcctgccaaccctgttctccagcttgtaga
ccctcccactgctggggagaaagttccgaggactgtcagaacttgacgagaactgtctgt
gccggtggctgtgcccgctgcaagggcccgcggcccaccgactgctgccatgagcagtgt
gctgccggctgcacaggccccaagcactccgactgcctggcctgcctccacttcaaccac
agcggcatctgtgagctgcactgcccatccctggtcatctacaacacggacaccttcgag
tccatgcccaaccctgagggccggtataccttcggcgccagctgtgtgaccgcctgtcct
tacaactacctgtctacggacgtgggatcctgcaccctggtctgtcccctgaacaaccaa
gaggtgacagctgaggacggaacacagcggtgtgagaaatgcagcaagccctgtgcccga
gtgtgctatggcctgggcatggaacacctgcgggaggtgagggcggtcaccagtgccaac
atccaggactttgctggctgcaagaagatctttgggagcctggcatttctgccggagagc
tttgagggggacccagcctccaacactgcccccctacagcctgagcagctcagagtgttt
gagaccctggaggagatcacaggttacctgtacatctcagcgtggccagacagcctgcct
gacctcagtgtcttccagaacctgcgagtaatccggggccgagttctgcatgatggtgcc
tactcgctgaccctgcaagggctgggcatcagctggttggggctgcgctcgctgcaggaa
ctgggcagcgggctggcccttgtccaccacaatgcccgcctctgcttcgtccacacggtg
ccctgggcccagctcttccggaacccccaccaggccctgcttcacagtgccaaccgccca
gaggacgagtgtgtgggcgagggcctggcctgctacccgctgtgcgcccacgggcactgc
tggggtccgggccccacccagtgtgtcaactgcagccagttccttcggggccaggaatgc
gtggaggaatgccgagtactgcaggggctcccccgggaatatgtgaaggacaggtactgt
ctgccgtgccaccccgaatgtcagccccagaatggctcagtgacttgctttggatcggag
gctgaccagtgtgtggcctgcacgcactacaaggacccgcccttctgcgtggctcgctgc
cccagcggtgtgaaacctgacctctccttcatgcccatctggaagttcccagatgaggag
ggcacgtgccagccgtgccccatcaactgcacccactcctgtttggacctggatgacagg
ggctgtcccgccgaacagagagccagccctgtgacatccatcattgctgctgtggtgggc
attttgctggtggtggtcattggtctggtcctcggcatcctaatcaagcgaaggcggcag
aagatccggaaatacacgatgcggaggctgctgcaggaaacggagctggtggagccgctg
acacctagcggagcgatgcccaaccaggctcagatgcgaatcctgaaagagacagagctg
aggaaggtgaaggtgcttggatccggagcttttggcacagtctacaagggcatctggatc
cctgatggagaaaatgtgaaaatcccagtggccatcaaagtgttgagggaaaacacatcc
cccaaagccaacaaagaaatcttggacgaagcatatgtgatggctggtgtgggctctcca
tatgtgtcccgcctcttgggcatctgcctgacatccacagtgcagctggtgacacagctt
atgccctatggctgcctcctagaccacgtccgagaacaccgcggccgcctgggctcccag
gacctgctgaactggtgtgtgcagattgctaaggggatgagctacttggaggatgtgcgg
cttgtgcacagggacctggctgcccggaatgtgctggtcaagagtcccaaccatgtcaag
attacagacttcgggctggctcggctgctggacattgacgagacagagtaccatgcggat
gggggcaaggtgcccatcaagtggatggcgttggagtccattctccgccggcggttcacc
caccagagtgatgtgtggagctatggtgtgactgtgtgggagctgatgacttttggggcc
aaaccttacgatgggatcccagctcgggagatccctgacctgctggagaagggggagcgg
ctgccccagccccccatctgcaccattgatgtctacatgattatggtcaaatgttggatg
attgactctgaatgtcggccgaggttccgggagttggtggccgaattctcccgcatggcc
agggacccccagcgctttgtggtcatccagaatgaggacttgggccctgccagccccttg
gacagcactttctaccgctcgctgctggaggatgatgacatgggggacctggtagatgct
gaggagtacctggtaccccagcagggcttcttctgcccggaccctgctcctggtgctggg
ggcacagcccaccgcaggcaccgcagctcatcctccaggagtggcggtggtgagctgacg
ctggggctggagccctcggaggaggagccccccaagtctccactggcaccttcagaaggg
gctggctctgatgtgtttgatggtgacttgggaatgggggcagccaaggggctgcagagc
ctcccacaacatgaccccagccctctacagaggtacagcgaggaccccacagtacccctg
cccccggagactgacggctatgttgcccccctgtcctgcagcccccagcctgaatacgtg
aaccagccagaggttcggccgcagcccccctcgcccctagagggccctctgtctccttgt
cgacctgatggtgccactttggaaaggcccaagactctctcccccgggaagaatggggtt
gtcaaagacgtttttgcctttgggggtgccgtggagaaccctgagtacttggcaccccgg
agcagagctgcccctcagccccaccctcctcctgccttcagcccagcctttgacaacctc
tattactgggaccaggacccatcagagcggggctctccacccagcacctttgaagggacc
cctacagcagagaacccggaatacctgggcctggacgtgccagtgtga
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integrated database retrieval system