KEGG   Equus caballus (horse): 100058665
Entry
100058665         CDS       T01058                                 
Symbol
PLCD4
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4 isoform X1
  KO
K05857  phosphatidylinositol phospholipase C, delta [EC:3.1.4.11]
Organism
ecb  Equus caballus (horse)
Pathway
ecb00562  Inositol phosphate metabolism
ecb01100  Metabolic pathways
ecb04020  Calcium signaling pathway
ecb04070  Phosphatidylinositol signaling system
ecb04919  Thyroid hormone signaling pathway
ecb04933  AGE-RAGE signaling pathway in diabetic complications
Module
ecb_M00130  Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:ecb00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    100058665 (PLCD4)
 09130 Environmental Information Processing
  09132 Signal transduction
   04020 Calcium signaling pathway
    100058665 (PLCD4)
   04070 Phosphatidylinositol signaling system
    100058665 (PLCD4)
 09150 Organismal Systems
  09152 Endocrine system
   04919 Thyroid hormone signaling pathway
    100058665 (PLCD4)
 09160 Human Diseases
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    100058665 (PLCD4)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:ecb04131]
    100058665 (PLCD4)
Enzymes [BR:ecb01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     100058665 (PLCD4)
Membrane trafficking [BR:ecb04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Phospholipases
    100058665 (PLCD4)
 Endocytosis
  Macropinocytosis
   Phospholipase C
    100058665 (PLCD4)
SSDB
Motif
Pfam: PI-PLC-X PI-PLC-Y EF-hand_like EF-hand_10 C2 EF-hand_7 PH EF-hand_6 EF-hand_1 EF-hand_5 PH_12 GDPD EF-hand_PLCG2 EF-hand_15 Wap1 EF-hand_8 DUF4028 EH
Other DBs
NCBI-GeneID: 100058665
NCBI-ProteinID: XP_023498110
Ensembl: ENSECAG00000012582
VGNC: 21541
LinkDB
Position
6:7995688..8015911
AA seq 804 aa
MAFLLQGRLPVNQDLLLMQKGMSMRKVRSKNWKKLRYFRLQDDGMTVWHARQAGGSAKPS
FSISDVETVREGHESELLRSLAEEFPLEQGFTVVFHGRRSNLDLVANSVDEARIWMQGLQ
LLVDFVTSMDQQEWQDQWLSDWFQRGDKNQDGRMTFQEVQRLLRLMNVEMDQEYAFQLFQ
TADTSQSGTLEGEEFVQFYKALTKRPEVQEIFENFSADGQKLTLLEFVDFLREEQKEGDH
ASDLALELIDRYEPSESGKLWHVLSMDGFLSYLCSKDGDIFNPTCRPIYQDMTQPLSHYY
INSSHNTYLVGDQLCGQSSVEGYIRALKRGCRCVEVDIWDGPSGEPIVYHGHTLTSRILF
KDVVATVAQYAFQTSDYPVILSLENHCSWEQQQIMVQHLTEILGELLLRTTLDGLLPTQL
PSPEELRRKVLVKGKKLRTLEEDLEEEEEEEELEPELEGEQEDEPELEAQFESESQKLSP
RSKDKKKEKVVMCPLFCPPPCCEVMVQAPISKPGVLLFPKQKFKPSLCPSLSALVVYLKS
VSFHSFTHSREHYRFYEISSFSETKAKSLIKEAGNEFVQHNAWQLSRVYPSGLRTDSSNY
NPQELWNAGCQMVAMNVQTAGLEMDIHDGLFRQNGGCGYVLKPDFLRDAQSSFHPERPIS
PCKAQTLIIQPWLQVISGQQLPKVNKTKEGSIVDPLVRVEIFGIRPDTTYQETNYVENNG
FNPYWGQTLCFRVLVPELALLRFVVKDYDWKSRHDFVGQYTLPWTCMKQGYRHIHLLSKD
GTSLQPASIFVHICTREGLEGDES
NT seq 2415 nt   +upstreamnt  +downstreamnt
atggcgttcctgctgcaaggccggctgcctgtcaatcaagacctcctgctgatgcagaaa
ggcatgtcgatgcgcaaggtgaggtccaaaaactggaagaaactgagatacttcaggctt
caggacgatggcatgacagtctggcatgcccgacaggctggaggcagtgccaagcccagc
ttctcaatctctgacgtggagacagtgcgtgagggccatgagtctgagttactgcgcagc
ctggcagaggagttccccctggagcaaggcttcactgtcgtcttccatggccgccgctcc
aacctggacctggtggccaacagtgttgacgaggcccggatctggatgcaggggctccag
ctgttggtggactttgtcaccagcatggaccaacaggagtggcaggaccaatggctgagt
gactggttccagcgtggagacaaaaaccaggatggtcggatgaccttccaagaagtccag
cggttactgcgcctgatgaatgtggaaatggaccaagaatatgccttccagcttttccag
acagcagacacgtcccagtctgggactctggagggagaagaatttgtccagttctataag
gcattgactaagcgtcctgaggtgcaggaaatctttgaaaacttttcagctgatgggcag
aagctgaccctgctggaatttgtggatttcctccgagaggagcagaaagaaggagaccat
gcttctgaccttgctctggaactcatcgaccgctatgagccttcagagagcggcaaactg
tggcacgtgctgagtatggacggcttcctcagctacctctgctcaaaggatggagacatc
ttcaacccgacctgccgccccatctaccaggatatgactcaacccctgagccactactac
atcaactcctctcacaacacctacctagtgggggatcagctttgtggccagagcagcgtc
gagggatatatacgggccctgaagcggggttgccgctgcgtggaggtggatatatgggat
ggacctagcggggaacctattgtttatcatggacacaccctgacctcccgcatcctgttc
aaagatgtcgtggccactgtagcacagtatgccttccagacatcagactatccagtcatc
ttgtccctggagaaccactgcagctgggagcagcagcagatcatggtacagcacctgacc
gagatcctgggggagctgctgctgagaaccaccttggatggactgctgcccactcagctg
ccctcacctgaggagcttcggaggaaggtcctggtgaaggggaagaaattaaggacactt
gaggaggatctggaggaagaggaagaggaggaagagctagagcctgaactggagggggag
caggaggatgagccggagctggaggcccagtttgagtctgagtcccagaagttgagccct
cgcagtaaagacaaaaagaaggagaaggttgtgatgtgcccgctgttttgtccgcctccc
tgttgtgaggttatggtccaggctcctatttccaagcctggggtccttctctttcccaag
cagaaattcaagcccagcttgtgtccatctctctctgccctggttgtgtacttgaagtct
gtctcattccacagcttcactcattcgagggagcactaccgcttctatgagatatcatct
ttttctgaaacgaaagccaagagcctcatcaaagaggctggcaatgagtttgtgcaacac
aacgcctggcagttaagccgtgtatatcccagtggcctgaggacagattcgtccaactac
aacccccaggaactctggaatgcaggctgccagatggtggctatgaatgtgcagactgcg
gggcttgagatggacatccatgatgggctcttccgccagaatggtggctgtggctacgtg
ctgaagccagacttcctgcgtgatgcccagagttccttccaccctgagaggcccatcagc
ccttgcaaagcccagaccctcataatccagccctggttgcaggtgatcagtggtcagcaa
ctccccaaagtgaacaagaccaaagagggctccattgtggatccactggtgagagtggag
atatttggcatccgcccagatacaacctaccaagagaccaactatgtggagaacaatggt
tttaatccatactgggggcagacactctgcttccgggtcctggtgcctgaactggcactg
ctgcgttttgtggtgaaagattatgactggaaatcccgacatgactttgttggtcagtac
accctgccttggacttgcatgaaacaaggttaccgccacatacaccttctctccaaggat
ggcaccagcctccagccagcttccatctttgtgcacatctgcacccgagaagggctggag
ggggatgaatcctga

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