Equus caballus (horse): 100059572
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Entry
100059572 CDS
T01058
Symbol
TOP2B
Name
(RefSeq) DNA topoisomerase 2-beta isoform X1
KO
K03164
DNA topoisomerase II [EC:
5.6.2.2
]
Organism
ecb
Equus caballus (horse)
Pathway
ecb01524
Platinum drug resistance
Brite
KEGG Orthology (KO) [BR:
ecb00001
]
09160 Human Diseases
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
100059572 (TOP2B)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:
ecb03032
]
100059572 (TOP2B)
03036 Chromosome and associated proteins [BR:
ecb03036
]
100059572 (TOP2B)
Enzymes [BR:
ecb01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.2 DNA topoisomerase (ATP-hydrolysing)
100059572 (TOP2B)
DNA replication proteins [BR:
ecb03032
]
Eukaryotic type
DNA Topoisomerases
100059572 (TOP2B)
Chromosome and associated proteins [BR:
ecb03036
]
Eukaryotic type
Chromosome condensation proteins
Other regulators of chromosome condensation
100059572 (TOP2B)
Centrosome formation proteins
Centriole proteins
100059572 (TOP2B)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
DNA_topoisoIV
TOPRIM_C
DNA_gyraseB
DTHCT
Toprim
HATPase_c
DUF7180
Microp_apicomplexa_20
Motif
Other DBs
NCBI-GeneID:
100059572
NCBI-ProteinID:
XP_023476606
Ensembl:
ENSECAG00000005608
VGNC:
50517
UniProt:
A0A9L0S7P4
LinkDB
All DBs
Position
16:58968155..59028501
Genome browser
AA seq
1620 aa
AA seq
DB search
MAKAGGGGAGAGGNGALTWVTLFDQNNAARKEELETANKNDPSKKLSVERVYQKKTQLEH
ILLRPDTYIGSVEPLTQLMWVYDEDVGMNCREVTFVPGLYKIFDEILVNAADNKQRDKNM
TCIKVSIDPESNIISIWNNGKGIPVVEHKVEKVYVPALIFGQLLTSSNYDDDEKKVTGGR
NGYGAKLCNIFSTKFTVETACKEYKHSFKQTWMNNMMKTSEAKIKHFDGEDYTCITFQPD
LSKFKMEKLDKDIVALMTRRAYDLAGSCKGVKVMFNGKKLPVNGFRSYVDLYVKDKLDET
GVALKVIHELANERWDVCLTLSEKGFQQISFVNSIATTKGGRHVDYVVDQVVSKLIEVVK
KKNKAGVSVKPFQVKNHIWVFINCLIENPTFDSQTKENMTLQPKSFGSKCQLSEKFFKAA
SNCGIVESILNWVKFKAQTQLNKKCSSVKYSKIKGIPKLDDANDAGGKHSLECTLILTEG
DSAKSLAVSGLGVIGRDRYGVFPLRGKILNVREASHKQIMENAEINNIIKIVGLQYKKSY
DDAESLKTLRYGKIMIMTDQDQDGSHIKGLLINFIHHNWPSLLKHGFLEEFITPIVKASK
NKQELSFYSIPEFDEWKKHIENQKAWKIKYYKGLGTSTAKEAKEYFADMERHRILFRYAG
PEDDAAITLAFSKKKIDDRKEWLTNFMEDRRQRRLHGLPEQFLYGTATKHLTYNDFINKE
LILFSNSDNERSIPSLVDGFKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSAYHHGEQ
ALMMTIVNLAQNFVGSNNINLLQPIGQFGTRLHGGKDAASPRYIFTMLSSLARLLFPAVD
DNLLKFLYDDNQRVEPEWYIPIIPMVLINGAEGIGTGWACKLPNYDAREIVNNVRRMLEG
LDPHPMLPNYKNFKGTIQELGQNQYAVSGEIFVVDRNTVEITELPVRTWTQVYKEQVLEP
MLNGTDKTPALISDYKEYHTDTTVKFVVKMTEEKLAQAEAAGLHKVFKLQTTLTCNSMVL
FDHMGCLKKYETVQDILKEFFDLRLSYYGLRKEWLVGMLGAESTKLNNQARFILEKIQGK
ITIENRSKKDLIQMLVQRGYESDPVKAWKEAQEKAAEEEETQNQHDDSSSDSGTPSGPDF
NYILNMSLWSLTKEKVEELIKQRDAKGREVNDLKRKSPSDLWKEDLAAFVEELDKVEAQE
REDILAGMAGKAIKGKVGKPKVKKLQLEETMPSPYGRRVVPEITAMKADASKKLLKKKKG
DLDTTAVKVEFDEEFSGTPVESTGEEALIPPTSINKGPKPKREKKEPGTRVRKTPTSSGK
SSAKKVKKRNPWSDDESKSESDLEETEPVVIPRDSLLRRAAAERPKYTFDFSEEEEEDAD
DDDDNNDLEELKVKASPITNDGEDEFVPSDGLDKDEYTFSPGKSKAIPEKSSHDKKTQDF
GNLFSFPSYSQKSEDDSAKFDSNEEDSASVFSPSFGLKQTDKVPSKTVAAKKGKPSSDTT
PKPKRTPKAKKVETVNSDSDSEFGIPKKTTTPKGKGRGAKKRKASGSENEGDYNPGRKTS
KPASKKPKKTSFDQDSDVDIFPSDFTSEPPSLPRTGRARKEVKYFAESDEEEDVDFAMFN
NT seq
4863 nt
NT seq
+upstream
nt +downstream
nt
atggccaaggcgggcggcggcggcgcgggagccggcggcaacggggcgctgacctgggtg
actctttttgatcagaacaatgctgcaagaaaagaagagttagaaactgcaaacaaaaat
gatccttcaaagaagttgtctgttgagagagtgtatcagaaaaagacacaacttgaacat
attctccttcgtcctgatacatacattggttcagtggagccattgacacagctaatgtgg
gtgtatgatgaagatgtaggaatgaattgcagagaggttacctttgtgccaggtttatac
aagatctttgatgagattttggttaatgcagctgacaataaacagagggataagaacatg
acctgtattaaagtttctattgatcctgaatctaacattataagcatttggaataatggg
aaaggcattccggtagtagaacacaaagtagagaaagtttatgttcctgcattaattttt
ggacagcttttaacatccagtaactatgacgatgatgagaaaaaagtaacaggtggtcgt
aatggttatggtgcaaaactttgtaatattttcagtacaaagtttacagtagagactgct
tgcaaagaatacaaacatagttttaagcagacatggatgaataatatgatgaagacttct
gaagccaaaattaaacattttgatggtgaagactacacgtgcataacattccaaccagat
ctgtccaaatttaaaatggaaaaacttgacaaggatattgtagcccttatgaccagaaga
gcttatgatttggctggttcttgcaaaggggtcaaggtcatgtttaatggaaagaaattg
cctgtaaatggatttcgcagttatgtagatctttatgtgaaagataaattggatgaaact
ggagtggccctgaaagttattcatgaacttgcaaatgaaagatgggatgtttgtctcaca
ttgagtgaaaaaggattccagcaaatcagctttgtaaatagtattgcaacaacaaaaggt
ggacgacatgtggattatgtagtagatcaagttgtcagtaaactgattgaagtagttaag
aaaaagaacaaggctggtgtatccgtgaaaccttttcaagtgaaaaaccatatatgggtt
tttattaactgccttattgaaaatccaacttttgattctcagactaaggaaaacatgact
ctgcagcccaaaagttttgggtccaaatgccaactgtcagaaaaattttttaaagcggcc
tctaactgtggcattgtagaaagtatcctgaactgggtgaaatttaaggctcagactcag
ctgaacaagaagtgttcgtcagtaaagtacagtaaaatcaaaggtattcccaaactggat
gatgctaatgatgctggtggcaaacattccctggagtgtacactgatactgacggaggga
gactctgccaaatcgctggctgtgtctggattaggtgtgattgggcgagatagatatgga
gtctttccactcaggggaaaaattcttaatgtacgggaagcttctcataaacagatcatg
gaaaatgcagaaataaacaatattattaaaatagttggtctacaatacaagaaaagttat
gatgatgcagaatccctgaaaactttacgctatggaaagattatgattatgactgatcag
gatcaagatggttctcacataaaaggtctgcttattaatttcatccatcacaattggcca
tcacttttgaagcatggttttcttgaagagttcattactcctattgtaaaggctagcaaa
aataagcaggaactttccttctacagtattcctgaatttgatgagtggaagaaacatata
gaaaaccagaaagcctggaaaataaaatactacaaaggattgggtaccagtacagctaaa
gaagcaaaggaatactttgctgatatggaaaggcaccgcatcttatttagatatgctggt
cctgaagatgatgctgccattaccttggcattcagtaagaagaagattgatgacagaaaa
gaatggttaacaaattttatggaagatcggagacagcgtaggttacatggcttaccagag
caatttttgtatggtacagcaacaaagcatttgacttacaatgatttcatcaacaaggaa
ttgattctcttctcaaactcagacaatgaaagatctataccatctcttgttgatggcttt
aaaccaggccaacgaaaagttttatttacctgtttcaagaggaatgataaacgtgaagtg
aaagttgcccaattggctggatctgttgcggagatgtctgcttatcatcatggggaacaa
gcattgatgatgactattgtgaatttggctcagaactttgtgggaagtaacaacattaac
ttgcttcagcctattggtcagtttggaactcggcttcatggtggcaaagatgctgcaagc
cctcgttatattttcacaatgttaagctctttagcaagattgctttttcctgccgtggat
gacaacctgcttaaattcctttatgatgacaatcaacgcgtagagcctgagtggtatatt
cccataattcccatggttttaataaatggtgctgagggcattggtactggatgggcttgt
aaactacccaactatgatgctagagaaattgtgaacaatgtcagacgaatgctagaaggc
ttggatcctcatcccatgcttccaaactacaaaaactttaaaggaacgatccaagaactt
ggtcaaaaccagtatgcagtcagtggtgaaatatttgtggtggatagaaacacagtagag
attacagagcttccagttagaacttggacacaggtatataaagaacaggttttagaacct
atgctaaatggaacagataaaacaccagcattaatttctgattataaagaatatcatact
gatacaactgtgaaatttgtggtgaaaatgactgaagagaaactagcacaagcagaagct
gctggactgcacaaagtttttaaacttcaaactactcttacttgtaattctatggtactc
tttgatcatatgggatgtctgaagaagtatgaaactgtgcaagacattttgaaagaattc
tttgatttacgattaagttattatggtttgcgtaaggagtggcttgtaggaatgctggga
gcagaatctacaaagcttaacaatcaagcccgtttcattttagagaagatacaagggaaa
attactatagagaataggtcaaagaaagatttgattcaaatgttagtccagagaggttat
gaatctgacccagtgaaagcctggaaagaagcacaagaaaaggcagcagaagaggaagaa
acacaaaaccagcatgatgatagttcctctgattcgggaactccttcaggccctgatttt
aattatattttaaatatgtctctgtggtctcttactaaagaaaaagttgaagaactgatt
aaacagagagatgcaaaagggcgagaggtcaatgatcttaaaagaaaatctccttcagat
ctttggaaagaagatttagcagcatttgttgaagaactggataaagtggaagcgcaagaa
cgagaagatattctggctggaatggctgggaaagcaataaaaggtaaagttggcaaacct
aaggtcaagaaacttcaattggaagagacaatgccctcaccttatgggagaagagtagtt
cctgaaattactgctatgaaggcagatgccagcaaaaagttgctgaagaagaaaaagggt
gatcttgataccacagcagtgaaagtggaatttgatgaagaattcagtggaacaccagta
gaaagtacaggagaagaggcattgatcccaccaacttctataaataaaggtcccaaaccc
aaaagggagaaaaaggagcctggtaccagggtgagaaaaacacctacatcatctggtaaa
tccagcgcaaagaaagtgaagaaacggaatccttggtcagatgatgaatctaagtcagaa
agtgacttggaggaaacagaacctgtggttattccgagagattctttgcttaggagagct
gctgctgaaaggcctaaatacacatttgatttctcagaagaagaggaggaggatgctgat
gatgatgacgacaataatgacttagaggaattgaaagttaaagcatctcccataacaaat
gatggggaagatgaatttgttccttcagatggcctagataaagatgaatatacattttca
ccaggcaaatcaaaagccattccagaaaaatcttcgcatgacaaaaaaactcaggatttt
gggaatctcttctcatttccttcatattctcagaagtcagaagatgattcagctaaattt
gacagtaatgaagaagattctgcttctgttttttcaccatcatttggtctgaaacaaaca
gataaagttccaagtaaaacagtagctgctaaaaagggaaaaccatcttcagatacaact
cctaagcccaagagaacccccaaagcgaagaaagtagagactgtaaactctgactcagat
tcagaatttggcattccaaagaagacgacgacaccaaaaggtaaaggccgaggggcaaag
aaaaggaaagcatctggctctgaaaatgaaggtgattataaccctggcaggaaaacatcc
aaaccagcaagcaagaaaccgaagaaaacatcttttgatcaggattcggatgtggatatc
ttcccatcagacttcacttctgagccaccttctctgccacggactggtcgggctaggaaa
gaagtaaaatattttgcggagtctgatgaagaagaagatgttgattttgcaatgtttaat
taa
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integrated database retrieval system
