Equus caballus (horse): 100060381
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Entry
100060381 CDS
T01058
Symbol
FH
Name
(RefSeq) fumarate hydratase, mitochondrial
KO
K01679
fumarate hydratase, class II [EC:
4.2.1.2
]
Organism
ecb
Equus caballus (horse)
Pathway
ecb00020
Citrate cycle (TCA cycle)
ecb00620
Pyruvate metabolism
ecb01100
Metabolic pathways
ecb01200
Carbon metabolism
ecb04934
Cushing syndrome
ecb05200
Pathways in cancer
ecb05211
Renal cell carcinoma
Module
ecb_M00009
Citrate cycle (TCA cycle, Krebs cycle)
ecb_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
ecb00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
100060381 (FH)
00620 Pyruvate metabolism
100060381 (FH)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
100060381 (FH)
09162 Cancer: specific types
05211 Renal cell carcinoma
100060381 (FH)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
100060381 (FH)
Enzymes [BR:
ecb01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.2 fumarate hydratase
100060381 (FH)
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SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Lyase_1
FumaraseC_C
Motif
Other DBs
NCBI-GeneID:
100060381
NCBI-ProteinID:
XP_023488568
Ensembl:
ENSECAG00000020726
VGNC:
18033
UniProt:
A0A9L0TAV2
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All DBs
Position
30:3447718..3481612
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AA seq
508 aa
AA seq
DB search
MYRALRLVARPRRLFRAPGAASAPDSCGAAALPCRPSSAARMASQNSFRIEYDTFGELKV
PNDKYYGAQTVRSTMNFKIGGVTERMPIPVIKAFGILKRAAAEVNQDYGLDPKIANAIMK
AADEVAEGKLNEHFPLVVWQTGSGTQTNMNVNEVISNRAIEMLGGELGSKKPVHPNDHVN
KSQSSNDTFPTAMHIAAAIEVHEVLLPGLQKLHDALDAKSKEFAQIIKIGRTHTQDAVPL
TLGQEFSGYVQQVKYATTRIQAAMPRIYELAAGGTAVGTGLNTRIGFAEKVAAKVAALTG
LPFVTAPNKFEALAAHDALVELSGAMNTTACSLMKIANDIRFLGSGPRSGLGELILPENE
PGSSIMPGKVNPTQCEAMTMVAAQVMGNHVAVTVGGSNGHFELNVFKPMMIKNVLHSARL
LGDAAVSFTENCVVGIQANTERISKLMSESLMLVTALNPHIGYDKAAKIAKTAHKNGSTL
KATAVELGYLTAEQFDEWVKPKDMLGPQ
NT seq
1527 nt
NT seq
+upstream
nt +downstream
nt
atgtaccgcgcgctccggctcgtcgcgcgcccacggcgcctcttccgggctccgggcgca
gcctcggctccggactcctgtggcgcggcggccctcccctgccggccctcgagcgccgcg
cgaatggcatctcaaaattcctttcggatcgaatatgatacctttggtgaactgaaggtc
ccgaatgataagtattatggtgcccagaccgtgagatccaccatgaactttaagattgga
ggtgtgacagagcgcatgcccattccagttattaaagcttttggcatcctgaagcgagcg
gctgctgaagtaaaccaggattatggtcttgatccaaagattgctaatgcaataatgaag
gcagcagatgaggtagctgaaggtaaattaaatgagcattttcctctcgtggtgtggcag
actggatcaggaacgcagacaaatatgaatgtaaatgaagtcattagcaatagagcaatt
gaaatgctaggaggtgaacttggcagcaagaagcccgtgcaccccaatgatcatgttaat
aaaagccagagctcaaatgacactttccccacagcaatgcacattgctgctgcaatagaa
gttcatgaagtgctgctcccaggactgcagaagctacacgatgccctcgatgccaagtcc
aaagagtttgcccagatcatcaaaattgggcgcactcacacacaggatgctgttccgctg
acgcttgggcaggaatttagcggttatgttcaacaagtgaagtatgcaacgacgagaata
caagctgccatgccgagaatctatgagctcgcagctggaggcactgctgtcggtactggt
ttgaatactagaattggctttgcagaaaaggttgctgccaaagtggctgcactcacaggc
ttgcccttcgtcacagctccgaataaatttgaagctctggctgctcatgatgctttggtt
gaactcagtggagccatgaacactaccgcttgcagtctgatgaagatagcaaatgatatt
cgatttctgggttctggtcctcgctccggtctgggagaactgatcttgcctgaaaatgaa
ccaggaagcagtattatgccaggcaaggtgaaccctacccagtgtgaagccatgaccatg
gttgcagcccaagtcatggggaaccacgtcgctgttaccgttggaggcagcaatggacat
tttgagttgaatgttttcaagccaatgatgattaaaaatgtgttacactcagccagactg
ctgggggatgcggcagtttccttcacagaaaactgcgtggtgggaatccaggccaacacg
gagaggatcagcaagctcatgagcgaatccctgatgttggtgacagctcttaatcctcat
atagggtatgacaaggcagcaaagattgctaagacggcacacaagaatgggtcaacctta
aaggcaactgccgtggagcttggctatctcacggcggagcagtttgatgagtgggtaaag
cccaaggacatgctgggtccacagtga
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