Equus caballus (horse): 100061676
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Entry
100061676 CDS
T01058
Symbol
PLCE1
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 isoform X3
KO
K05860
phosphatidylinositol phospholipase C, epsilon [EC:
3.1.4.11
]
Organism
ecb
Equus caballus (horse)
Pathway
ecb00562
Inositol phosphate metabolism
ecb01100
Metabolic pathways
ecb04014
Ras signaling pathway
ecb04015
Rap1 signaling pathway
ecb04020
Calcium signaling pathway
ecb04024
cAMP signaling pathway
ecb04070
Phosphatidylinositol signaling system
ecb04919
Thyroid hormone signaling pathway
ecb04933
AGE-RAGE signaling pathway in diabetic complications
ecb05205
Proteoglycans in cancer
Module
ecb_M00130
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:
ecb00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00562 Inositol phosphate metabolism
100061676 (PLCE1)
09130 Environmental Information Processing
09132 Signal transduction
04014 Ras signaling pathway
100061676 (PLCE1)
04015 Rap1 signaling pathway
100061676 (PLCE1)
04020 Calcium signaling pathway
100061676 (PLCE1)
04070 Phosphatidylinositol signaling system
100061676 (PLCE1)
04024 cAMP signaling pathway
100061676 (PLCE1)
09150 Organismal Systems
09152 Endocrine system
04919 Thyroid hormone signaling pathway
100061676 (PLCE1)
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
100061676 (PLCE1)
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
100061676 (PLCE1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
ecb04131
]
100061676 (PLCE1)
Enzymes [BR:
ecb01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.11 phosphoinositide phospholipase C
100061676 (PLCE1)
Membrane trafficking [BR:
ecb04131
]
Exocytosis
Calcium ion-dependent exocytosis
Phospholipases
100061676 (PLCE1)
Endocytosis
Macropinocytosis
Phospholipase C
100061676 (PLCE1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PI-PLC-X
PI-PLC-Y
RasGEF
RA
C2
EF-hand_like
GDPD
Motif
Other DBs
NCBI-GeneID:
100061676
NCBI-ProteinID:
XP_001502425
VGNC:
51637
UniProt:
F6TBW2
LinkDB
All DBs
Position
1:complement(35036651..35335165)
Genome browser
AA seq
2299 aa
AA seq
DB search
MTSEEMAASVLIPVTQRKVISVQGAVDESSEKVSDISVPKVHTIRQSGPTSHAISQLNTL
KEESSGSNLPKIFSIAREKIMSDENSNEKCWEKTMPDSVKNLNINCNNILKNLPQSQFYE
TCDSVTEEGLCMETGIPSSLERKVFPGIQLEIDGPPKDVSPLGNQSAIMDTSRARSDSNM
AVFHFHYEVDRGMSDTFCTLSDNLILDDCGNCVPLPGVGGEQKKNYMAYTCKLMELAKNC
DNKNGQLQCDHCDTLNDKYLCFEGSCQKANVVFSSDSFCKEDFTDSPPAKTFLSHLEDFP
DNCEDVEEDFFKSKKERSTLLVRRFCKNDREVKKSVYTGTRAIVRTLPSGHIGLGAWSYI
DQKRNGLLLPCGRVTERLSTVVTGQDGSRCLSEAQWYPIYTAVRRGEGTEDTIGSLLHVF
TELPASERAHERISIGPCLKQCVRDTVCEYRATLQRTSISQYITGSLLEATTSLGARSGL
LNTFGGSTGRMMMKERQPGTSMANSSALPSSSAGISKELIDLQPLIQFPEEVASILMEQE
QNIYRRVLPVDYLCFLTRDLGTPECQRSLPCLKASISASILTSQNGEHNALEDLLMRFNE
VSSWVTWLILTAGSMEEKREVFSYLVHVAKCCWNMGNYNAVMEFLAGLRSRKVLKMWQFM
DQSDLETMRSLKDAMAQHESSCEYRKVVTRALHIPGCKVVPFCGVFLKELCEALDGASGL
MKLCPRYNSQEETLEFVADYSGQDNFLQRVGQNGLKNSEKESTVNSIFQIIRSCSRSLET
EEEDSPSEGNSSRKNSLKDKARWQFIIGDLLDSENDIFEQPKEWDPHGSEEPQKAFDHGT
ELIPWYVLSIQADVHQFLLQGATVIHYDQDMHLSARCFLRLQPDNSTLTWMKPTTASPAS
AKAKLGVLSNTSEPGKFPLLGSAGLSSLVEGVLDLFSAKAVYMGHPSIDIHTVCVQNKLG
SMLLSETGVTLLYGLQTTDNRLLHFVAPKHTAKMLFSGLLELTKAVRKMRKFPDQRQQWL
RKQYVSLYQEDGRYEGPTLAHAVELFGGRRWSTRNPSPGTSAKSAEKPNVQRNNTLGIST
TKKKKKILMRGESGEATDDEMATRKVKVHKECRSRSGSDPQDANEPEESEANAITSPPNP
LPSRRAHSLTTAGSPNLASGTSSPIRPVSSPVLSSSNKSPSSAWSSSSWHGRIKGGMKGF
QSFMVSDSNMSFIEFVELFKSFSVRSRKDLKDLFDIYAVPCNRAGSESAPLYTNLTIDEN
TSGLQPDLDLLTRNVSDLGLFIKSKQQLSDNQRQISDAIAAASIVTNGTGIESTSLGIFG
VGILQLNDFLVNCQGEHCTYDEILSIIQKFEPSVSMCHQGLMSFEGFARFLMDKDNFASK
NDESQENSRELQLPLSYYYIESSHNTYLTGHQLKGESSVELYSQVLLQGCRSIELDCWDG
DDGMPIIYHGHTLTTKIPFKEVVEAIDRSAFITSDLPIIISIENHCSLPQQRKMAEIFKT
VFGEKLVAKFLFESDFSDDPMLPSPDQLRRKVLLKNKKLKAHQTPVDILKQKAHQLASMQ
AQAYNGGNANPPPANNEEEEDEEDEYDYDYESLSDDNILEDRPENKSCNDKLQFEYNEEI
PKRIKKADNSACNKGKVYDMELGEEFYLPQNKKESRQIAPELSDLVIYCQAVKFPGLSTL
NASGSSRGKERKSRKSIFGNNPGRMSPGETASFNKTSGKSSYEGMRQAWEESSSPLNPTT
SLSAIIRTPKCYHISSLNENAAKRLCRRYSQKLIQHTACQLLRTYPAATRIDSSNPNPLM
FWLHGIQLVALNYQTDDLPLHLNAAMFEANGGCGYVLKPPVLWDKNCPMYQKFSPLERDL
DNMEPAVYSLSIVSGQNVCPSNSTGSPCIEVDVLGMPLDSCHFRTKPIHRNTLNPMWNEQ
FLFRVHFEDLVFLRFAVVENNSSAVTAQRVIPLKALKRGYRHLQLRNLHNEILEISSLFI
NSRRMEENSSSNTVPSSLMFNTEERKCLQTHRVTVHGVPGPEPFTVFSINGGTKAKQLLQ
QILATEQDTKPIATDYFLMEEKYFISKEKNECRKQPFQRAIGPEEEIMQILSSWFPEEGY
VGRIVLKTQQENLEEKNIVPEDKEVILSSEEESFFVQVHDVSPEQPRTVIKAPRVSTAQD
VIQQTLCKAKYSYSILSNPNPSDYVLLEEVVKDTTNKKSSTPKSSQRVLLDQECVFQAQS
KWKGAGKFILKLKEQVQASREDKRKGISFASEFKKLTKSTKQPRGLTSPSQVLASESVQN
KEEKPVGSLSSSDTTDYRQ
NT seq
6900 nt
NT seq
+upstream
nt +downstream
nt
atgacttctgaagaaatggcagcttctgttctcatacctgtgactcagagaaaagtgata
tctgttcaaggggctgttgatgaaagtagtgaaaaggtctcagacatcagtgttccaaaa
gtgcatactatcagacagagtgggccaacttctcatgccatctcacaactgaacacactt
aaagaagaatcttctggaagcaacttgcccaagattttctccatagcaagggagaaaata
atgagtgacgagaacagtaatgaaaagtgctgggagaaaaccatgccagattctgtgaaa
aaccttaacattaactgtaacaacatattgaaaaaccttcctcagagccagttttatgaa
acatgtgattctgtcacagaggaaggcctgtgtatggaaactggaatcccttcttcactg
gaaagaaaggtgttccctggaattcaactggaaatagacggacctcccaaggacgttagt
cccttaggaaatcaatcagcgatcatggataccagcagggcacgctctgacagcaacatg
gcggtatttcactttcactatgaagttgacagaggaatgtcagacactttctgtaccctg
tcagataacttgattttggatgattgtggaaactgtgtaccactgcctggtgttggtgga
gagcaaaagaaaaattacatggcgtatacttgtaaactgatggaattggcaaaaaactgt
gataataagaatggacagctgcagtgtgatcattgtgacaccttgaatgacaaatacttg
tgctttgaaggttcttgccagaaggccaatgtggtattttcaagcgacagcttttgcaag
gaggattttactgacagtcctcctgcgaagacctttctgagccatttggaagacttccct
gataattgtgaagatgtagaagaagattttttcaaaagcaaaaaggagcgatccactttg
ttagtgaggagattttgtaaaaatgacagggaagttaagaaatctgtgtacactgggaca
agggcaattgtgagaactctgccttctggtcacattgggctgggagcttggagttacatt
gatcagaagagaaatggtctcttgttgccctgtgggagagtaacggaacggctgtcaaca
gtggtgactgggcaagatgggagccggtgtctgtcagaagcccagtggtatccgatctac
actgcagtgagaaggggagaaggaacagaagatacaattggatctcttctccatgtcttc
acagagctcccagcctctgagagagcccatgaaaggattagcattggtccgtgcttaaag
caatgtgtccgagacaccgtgtgtgagtatcgtgccaccctccaaaggacttccatatcg
cagtacatcaccggttctctcctagaagcaaccacatctttaggagcacgaagtggcctt
ctcaatacttttggaggatccactggacgaatgatgatgaaagaacgccaaccgggcacc
tctatggccaattccagtgccctcccttcaagttccgctgggatcagcaaggaactgatt
gatctgcagcccctcatccagttcccagaagaggtcgccagcatcctgatggagcaggag
cagaatatttaccgaagggtcttgccagttgactatctttgcttcttgacccgggacttg
ggcactccggaatgccagaggtctctgccctgcctcaaagcgtccatctcagcatcaatt
cttacctcccagaacggagaacacaatgcccttgaagatctcctgatgagatttaatgag
gtgagctcctgggtaacgtggctgatcctcaccgcgggctccatggaggagaagcgggaa
gtcttctcatatttggtgcatgtggccaaatgctgctggaacatgggcaactacaatgct
gtcatggagttcttggctggcctcaggtcaagaaaagttttaaaaatgtggcagttcatg
gaccagtctgacctggagaccatgaggagcctgaaggatgccatggctcagcacgaatct
tcctgtgagtacaggaaggtggtgacgcgggcactgcacatccccggctgtaaggtggtt
ccgttctgtggggtgtttctgaaggagctgtgtgaagcgctcgacggagcctccggcctc
atgaagctttgcccgaggtacaattcccaggaagaaactctagagtttgtagctgattat
agtggacaagataatttcttacaacgtgtgggacaaaatggcttaaagaattcagagaag
gagtccacagtcaacagcatctttcagatcatcagaagctgtagtcgaagtctcgagacc
gaggaggaggacagccccagtgaagggaacagctctaggaaaaattccttgaaggataaa
gccagatggcagtttataattggagatttgctagattctgaaaatgacatctttgagcag
cccaaagaatgggaccctcatggatcagaagagccacagaaggcgtttgaccatgggaca
gagctcatcccgtggtacgtgctgtctatccaagctgatgtgcaccagttcctgttgcag
ggggccacggtcatccactacgaccaggacatgcacctctctgcccgctgcttcctccgg
cttcagcctgacaatagcaccttgacctggatgaagcccaccactgcctccccagccagt
gctaaagcgaaacttggtgtacttagtaacacgtctgagcctggtaaattcccgttactg
ggcagtgctggattaagcagcctggtggagggggtcttggatctgttttcagcaaaggct
gtgtacatgggacaccctagcattgatatacacactgtgtgtgttcagaacaaactgggt
agcatgcttctctcagagactggtgtaacgctgctctatgggcttcagaccacggacaat
aggttattgcactttgtggcaccaaagcacacagctaaaatgctcttcagcggattgttg
gaactcacgaaagctgtaagaaagatgaggaagttccctgaccaaagacagcagtggctg
cggaaacaatacgtcagcctctatcaggaagatggacggtatgaaggcccaactttggct
catgctgtggagttgtttggtggcagacgatggagtactcgaaaccccagccctgggaca
tcagcaaagagtgccgagaagcccaacgtgcagagaaacaacaccttgggcataagtacc
accaagaaaaagaagaaaatcctgatgaggggtgagagtggagaggcaaccgacgatgag
atggccacccgcaaggtcaaagtgcacaaagagtgtcggagccggagcggttctgaccct
caagatgctaacgaaccagaggaatcagaggcgaatgccatcacgagccctccgaaccct
ctcccttccagaagagcccactctttgaccacggctgggtcccctaacttggcttccggg
acgtcatctcccatcaggccagtgtcctcccctgtgctgtcttcttcaaacaagagcccg
tccagtgcttggagcagcagcagctggcacgggcggatcaaaggaggaatgaagggcttt
cagagcttcatggtttcagacagtaacatgagtttcattgaatttgttgagctgttcaaa
tcattcagtgtacggagccgcaaggacctgaaggatctctttgacatctatgctgtgcca
tgcaaccgagccggctccgagtcggccccgctctacaccaacctcacaatcgatgaaaac
accagcggtcttcagcctgacctagatttgttgaccagaaatgtctcggatttggggttg
ttcattaagagtaaacagcagctgtcagacaaccagaggcagatatccgatgccattgct
gctgcaagtatcgtgacaaacggcactgggatcgagagcacgtccctgggcatatttggg
gtaggcatactccagctcaatgacttcctagtgaattgccaaggagaacattgcacttac
gatgaaatcctcagcatcatccagaagttcgagcccagcgttagtatgtgtcatcagggc
ctaatgtcgtttgaaggatttgcaaggtttctgatggataaagataattttgcctcaaaa
aatgacgagtcacaggagaacagtagagaattgcagctgcccctctcctactactacatt
gaatcttcacacaatacctacctcacaggccatcagctcaaaggagaatcctcagtagaa
ctctacagccaggtcctcctgcaaggctgtaggagcatagagttggactgctgggatgga
gatgatgggatgcccatcatttatcatggacataccctgacaaccaagatccccttcaag
gaagtggttgaagccattgatcgaagtgccttcatcacctctgacctgccaatcatcata
tcaattgagaaccactgttcattgcctcagcaacgaaaaatggcagaaattttcaagact
gtttttggagaaaaactggtggctaaattcttatttgagagtgatttctcagatgatcca
atgcttccctcacctgaccaacttagaagaaaagtgcttcttaaaaataagaagctgaaa
gcccatcagaccccagtggatatcttaaagcaaaaggctcatcagttagcatccatgcaa
gctcaggcatataatggcgggaatgccaaccctccacctgctaataacgaggaagaggaa
gatgaagaggacgaatatgattatgactatgaatccctctctgatgacaacattctagaa
gacagacctgaaaataaatcatgtaatgacaagcttcagtttgagtataatgaagaaatc
cccaagaggataaagaaagcagataactctgcttgcaacaaaggaaaggtttatgacatg
gaactgggagaagaattttatcttcctcagaataaaaaggaaagcagacagattgcacca
gagctttctgacctggtcatctattgccaagcagtaaaatttccaggcctgtcaactcta
aatgcatctggctctagcagaggaaaagaaaggaaaagcaggaagtccatttttggcaac
aatccgggcagaatgagccctggagagacagcatcgtttaacaaaacatctggaaaaagt
tcctatgaaggaatgcgacaggcctgggaggaatcatcttcccccctcaacccaaccacg
tccctcagcgctatcattagaactcccaaatgttaccatatctcgtcgctgaatgaaaat
gccgccaagcgtctgtgtcgcaggtattcccagaaactgatccagcacaccgcctgtcag
ctgctgaggacttacccggccgccacccgcatcgactcgtccaaccccaatcctctcatg
ttctggctccatgggatacagcttgtggccctcaactaccagacagatgatctccctttg
catttaaatgctgccatgtttgaggccaacggtggctgtggttatgttttgaaaccccca
gttctgtgggacaagaactgtcccatgtatcagaagttttctcccttggaaagagacctg
gacaacatggagcctgctgtctattctttatctattgtctctggtcaaaacgtgtgcccg
agtaacagcacgggaagcccgtgtattgaagttgacgtcctgggcatgcccctggacagc
tgccacttccgcacgaagcccatccatcgaaataccctgaaccccatgtggaacgaacag
tttctcttccgggttcactttgaagatctcgtatttctccgttttgcagttgtggaaaac
aatagctcggcggtaactgctcagagggtcattccactcaaggctttaaaacgaggatat
cgacatcttcagctacgaaacctccacaatgaaatcttggagatctccagtttattcata
aacagcagaaggatggaagaaaattcctccagcaatactgtgccgtcctctttgatgttt
aatacagaagaaagaaaatgtttgcagactcacagagtcacggtgcatggggtccctggt
ccagagccctttactgttttctctataaatggaggcacaaaggcaaagcagcttctccag
caaattctggccactgaacaagacaccaaacctattgccacagactattttttgatggaa
gaaaaatatttcatatctaaagaaaagaatgaatgcaggaaacaacccttccagagagcc
attggtccagaagaagagatcatgcagattttaagcagctggtttccagaagaaggatat
gttggcaggattgtcttgaaaacccagcaggaaaacctagaagagaaaaacattgttcca
gaggacaaggaggtgatcctgagctcggaggaggagagcttctttgtccaagtgcacgac
gtttctccggagcaacctcgaacagtcatcaaagcgcctcgagtcagcacggcgcaggac
gtcattcagcagaccttatgcaaagccaaatattcctatagcatcctgagcaaccccaac
ccaagtgactatgtgcttttggaagaggtagtgaaagacacgaccaacaagaagtcttct
accccgaagtcctcccagcgggtccttttggatcaggagtgtgtgtttcaagcacaaagc
aagtggaaaggtgcaggaaaattcatccttaagctaaaggagcaggtacaggcatcccga
gaagacaaaagaaaaggcatatcttttgccagtgaattcaagaagctcaccaagtcaact
aaacagccccgaggactcacatcgccttctcaggtcttggcctcagaaagtgtccaaaac
aaggaggagaagcctgtgggcagcttgtcctccagtgacacgacagactatcgacagtga
DBGET
integrated database retrieval system
