Equus caballus (horse): 100062488
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Entry
100062488 CDS
T01058
Symbol
PFAS
Name
(RefSeq) phosphoribosylformylglycinamidine synthase
KO
K01952
phosphoribosylformylglycinamidine synthase [EC:
6.3.5.3
]
Organism
ecb
Equus caballus (horse)
Pathway
ecb00230
Purine metabolism
ecb01100
Metabolic pathways
Module
ecb_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
ecb00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
100062488 (PFAS)
Enzymes [BR:
ecb01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
100062488 (PFAS)
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Gene cluster
GFIT
Motif
Pfam:
GATase_5
FGAR-AT_PurM_N-like
AIRS_C
FGAR-AT_N
FGAR-AT_linker
AIRS
Motif
Other DBs
NCBI-GeneID:
100062488
NCBI-ProteinID:
XP_001918417
Ensembl:
ENSECAG00000014762
VGNC:
21332
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Position
11:51476168..51492436
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AA seq
1337 aa
AA seq
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MSSVLHFYVRPSGHEGAASGHTRRKLQGKLPELQSITTELCYNVNWTAESLPSAEEMKKL
MWLFGCPLLLDDVAQESWLLPGSSDLLLEVGPRLNFSTPTSTNIVSVCWAAGLGAVDRVE
TTRRYLLSFAHPPSAEMEAIAVATLHDRMMEQHFPHPIQSFSLGSIPVPLNGPINILTEG
RPALEKANQELGLALDSWDLDFYTKRFQELQRNPSIVEAFDLAQSNSEHSRHWFFKGRLH
VDGQELAHSLFESIMSTQASSNPNNILKFCDNSSAIQGEEVQFLRPEDPTQPSRFQQQQG
LRHVVFTAETHNFPTGVAPFSGATTGTGGRIRDVQCTGRGAHVVAGTAGYCFGNLHIPGY
TLPWEDPSFQYPGNFAQPLEVAIEASNGASDYGNKFGEPVLAGFARSLGLQLPDGQRREW
IKPIMFSGGIGSMEAEHVSKEPPEPGMDVAKVGGPVYRIGVGGGAASSVQVQGDNASDLD
FGAVQRGDPEMEQKMNRVIRACVEAPMGNPICSLHDQGAGGNGNVLKELSDPAGAVIYTS
RFQLGDPTLNALEIWGAEYQESNALLLRPPHRDFLSRVSTRERCPACFVGTITGDRRIVL
VDDRQCPVERDGQGDAPPTPPTPVDLELDWVLGKMPRKEFFLQRNLPVLQPLALPPGLSV
RQALERVLRLPAVASKRYLTNKVDRSVGGLVAQQQCVGPLHTPLADVAVVALSHQELIGA
ATALGEQPVKSLLDPKVAARLAVAEALTNLVFALVTDLRDVKCSGNWMWAAKLPGEGAAL
ADACEAMVAVMVALGVAVDGGKDSLSMAARVGSETVRAPGSLVISAYAVCPDITATVTPD
LKCPGGRGHLLYVPLSPGHHRLGGTALAQCFSQIGEQPPDLDLPENLVRAFSITQGLLKD
RLLCSGHDVSDGGLITCLLEMAFAGNCGIEADVPAPGVNALPVLFAEEPGLVLEVQEPDV
AQVLKRYQDAGLHCLELGHTGDAGPHAVVRVSVNGAVVLEEPVGQLRALWEETSFQLDRL
QAEPSCVAEEEQGLRERTGPSYCLPPTFPKASVPREPGGPTPRVAIMREEGSNGDREMAD
AFHLAGFEVWDVTMQDLCSGAIGLDTFRGIAFVGGFSFADVLGSAKGWAAAVTFHPQAGA
ELRRFRKRPDTFSLGVCNGCQLLALLGWVGGNPNEEAGEMGLDSWPAQPGLLLRHNLSGR
YESRWASVRVGPGPALMLRGMEGAVLPVWSAHGEGYMAFSSPELQAQIEAKGLAPLHWAD
DDGNPTEQYPLNPNGSPGGVAGLCSLDGRHLALMPHPERSVRPWQWAWRPPPFDTLTTSP
WLQLFINAREWTREGGC
NT seq
4014 nt
NT seq
+upstream
nt +downstream
nt
atgtcctcagtccttcacttctatgtccgtccctctggccatgagggggcagcctctgga
cacactcgaaggaagctgcaggggaaactaccagagctgcagagcatcacgactgagctg
tgctacaacgtgaactggacagcggagtccctcccaagcgctgaggagatgaagaagctg
atgtggttatttggctgccccttgttattggatgatgttgctcaggagtcctggctcctt
cctggctccagtgacctgcttctggaggttgggcccaggctgaacttctccaccccaacg
tctaccaacatcgtgtcagtgtgctgggccgctgggctgggggctgtggatcgtgtggag
actacccggcgctacctgctctcgtttgcccaccccccttcagctgagatggaggccatt
gctgtggctaccctgcatgacaggatgatggagcagcacttcccccatcctatccagagc
ttctcccttgggagcatcccagtaccactcaacggccctatcaacatactgaccgagggc
cggcctgccctggagaaagccaaccaggaactaggtctggctctagactcctgggaccta
gatttctataccaagcgcttccaggagctacagcggaaccccagcatcgtagaggccttc
gacttggctcagtccaacagcgagcatagccgacactggttcttcaagggccgactccac
gtggatgggcaggaactggcacactcactgtttgagtccatcatgagcacccaggcctct
tcaaaccccaacaacatcctcaagttctgtgacaatagcagtgcaatccagggggaggag
gtccaattcctacggcctgaggaccccacacagccaagccgcttccagcaacagcagggg
ctgagacacgtggtcttcacagcagagacacacaacttccccacaggagtagcccccttc
agcggtgcaaccacaggcacagggggccgtatccgagatgtccagtgcacaggccgcggg
gcccacgtggtagctggcactgctggctattgctttggaaacctgcacatcccaggttac
actctgccctgggaggatccgagcttccagtatcctgggaactttgcccagcctctggag
gttgccattgaggccagtaatggagcttctgactacggcaacaagtttggggaaccagtg
ctggccggcttcgcccgctccttgggcctccagctcccagacggccagcggcgtgagtgg
atcaagcccatcatgtttagtgggggcattgggtccatggaagctgagcatgtgagcaag
gagcccccagagccaggcatggatgttgcaaaggttgggggtcctgtctacaggattgga
gttggaggtggagctgcttcgtctgtgcaggtgcagggagacaacgccagtgacctggac
tttggggctgtgcaacggggagacccagagatggaacagaagatgaaccgtgtgatccgg
gcttgtgtggaggcccccatgggaaaccccatctgcagcctccatgaccagggtgctggt
ggcaatggcaacgtcctgaaggagctgagtgaccccgcgggagccgtcatttacaccagc
cgcttccagctcggggatccgaccctgaacgccctggaaatctggggggctgagtaccag
gagtcgaatgcacttttgctgaggcccccccaccgggacttcctcagtcgtgtcagcacc
cgggaacgctgcccagcttgctttgtgggcaccatcactggagacaggagaatagtgctg
gtggatgatcggcagtgtcctgtggagagagatggccagggggatgcccctccaacccca
ccaacccctgtggacctggagctggattgggtgctgggcaagatgcctcggaaggagttc
ttcctccagaggaatctcccggtgctgcagcctctggccttgcccccggggctgagcgtg
cgccaggctctggagcgggtcctgaggctgcctgccgtggccagcaagcgctacctcacc
aacaaggtggaccgctctgtgggtggcctggtggcgcagcagcagtgtgttgggcccctg
catacccctctggcagacgtggcggtcgtggcactgagtcaccaggagctcataggggcc
gccacagccctgggagagcagccagttaagagcctattggaccccaaggtcgctgcccgg
ctggccgtggccgaagccctcaccaacctggtgttcgctctggtcactgacctccgggat
gtgaagtgcagtgggaactggatgtgggcagccaagctcccaggagagggtgcagctctg
gctgacgcctgtgaggccatggtggcagtgatggtggccctgggtgtggcagttgatggt
ggcaaggactctctcagcatggctgcccgggttggctctgagaccgtgcgggctcctgga
tctctggtcatctcagcctatgctgtctgtccagacattacagccactgtgaccccagac
ctcaagtgtcctggagggagaggccatctgctctatgtccccctgagtcctgggcaccac
cggctggggggtacagctctggcccagtgcttctcccagattggtgagcagcctcccgat
ctggaccttccggagaacttggtgcgtgccttcagcatcacccaggggctgctaaaagat
cgcctcctctgctcaggccatgatgtcagcgacgggggtctcatcacctgcctgctagag
atggcctttgctgggaattgtgggatagaggcagatgtacctgcccctggggtcaatgcg
ctgcctgtgctgtttgccgaggagccaggcctggtgctggaggtgcaggagccagacgtg
gctcaagtgctgaagcgttaccaggatgcaggcctccactgcctggagctgggccacacg
ggcgatgccgggccccacgccgtggtccgggtgtcagtgaatggggctgtggttctggag
gagcctgttgggcagctgcgagccctctgggaagagacgagtttccagctggaccggctg
caggcagagccgagctgtgtggccgaggaagaacaggggctgagggagcggacagggccc
agctactgcctgccccccacctttcccaaagcttccgtgccccgcgagcctggaggtccc
accccccgagtcgccatcatgcgagaggagggcagtaacggagaccgggagatggctgat
gccttccacttggctgggtttgaggtgtgggatgtgaccatgcaggacctctgttctggg
gcaatcgggctggacacattccgcggcatagccttcgtgggtggcttcagcttcgcagat
gtcctgggctctgccaaagggtgggcggctgcggtgacctttcatccacaggccggggct
gagctgaggcgcttccggaagcggccagacacctttagcctgggcgtgtgtaacggctgt
cagctgctggctctgctgggctgggtgggaggcaatcccaatgaggaggcaggggagatg
ggccttgactcctggccagcccagcccggcctcctgctgcgccacaacctgtctgggcgt
tatgagtctcgctgggccagtgtgcgcgtggggcctgggccggccctgatgctgcgaggg
atggagggagccgtgctgcctgtgtggagcgcccatggagaaggttacatggcattttct
tctccggaactgcaagcccagattgaggccaagggcttggctccactgcactgggcagac
gatgacgggaaccccacagaacagtaccctctgaatcccaatgggtccccagggggcgtg
gctggcctctgctcccttgatggccgccacctggctctcatgcctcaccctgagcggtct
gtgagaccttggcaatgggcatggcgacccccaccatttgacactctgaccacctccccc
tggctccagctcttcatcaatgcccgagagtggacccgggaaggaggctgctga
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