Equus caballus (horse): 100063339
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Entry
100063339 CDS
T01058
Symbol
NOS3
Name
(RefSeq) nitric oxide synthase, endothelial
KO
K13242
nitric-oxide synthase, endothelial [EC:
1.14.13.39
]
Organism
ecb
Equus caballus (horse)
Pathway
ecb00220
Arginine biosynthesis
ecb00330
Arginine and proline metabolism
ecb01100
Metabolic pathways
ecb04020
Calcium signaling pathway
ecb04022
cGMP-PKG signaling pathway
ecb04066
HIF-1 signaling pathway
ecb04071
Sphingolipid signaling pathway
ecb04151
PI3K-Akt signaling pathway
ecb04370
VEGF signaling pathway
ecb04371
Apelin signaling pathway
ecb04611
Platelet activation
ecb04915
Estrogen signaling pathway
ecb04921
Oxytocin signaling pathway
ecb04926
Relaxin signaling pathway
ecb04931
Insulin resistance
ecb04933
AGE-RAGE signaling pathway in diabetic complications
ecb05415
Diabetic cardiomyopathy
ecb05417
Lipid and atherosclerosis
ecb05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
ecb00001
]
09100 Metabolism
09105 Amino acid metabolism
00220 Arginine biosynthesis
100063339 (NOS3)
00330 Arginine and proline metabolism
100063339 (NOS3)
09130 Environmental Information Processing
09132 Signal transduction
04370 VEGF signaling pathway
100063339 (NOS3)
04371 Apelin signaling pathway
100063339 (NOS3)
04066 HIF-1 signaling pathway
100063339 (NOS3)
04020 Calcium signaling pathway
100063339 (NOS3)
04071 Sphingolipid signaling pathway
100063339 (NOS3)
04022 cGMP-PKG signaling pathway
100063339 (NOS3)
04151 PI3K-Akt signaling pathway
100063339 (NOS3)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
100063339 (NOS3)
09152 Endocrine system
04915 Estrogen signaling pathway
100063339 (NOS3)
04921 Oxytocin signaling pathway
100063339 (NOS3)
04926 Relaxin signaling pathway
100063339 (NOS3)
09160 Human Diseases
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
100063339 (NOS3)
05418 Fluid shear stress and atherosclerosis
100063339 (NOS3)
05415 Diabetic cardiomyopathy
100063339 (NOS3)
09167 Endocrine and metabolic disease
04931 Insulin resistance
100063339 (NOS3)
04933 AGE-RAGE signaling pathway in diabetic complications
100063339 (NOS3)
Enzymes [BR:
ecb01000
]
1. Oxidoreductases
1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
1.14.13.39 nitric-oxide synthase (NADPH)
100063339 (NOS3)
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Gene cluster
GFIT
Motif
Pfam:
NO_synthase
FAD_binding_1
Flavodoxin_1
NAD_binding_1
Motif
Other DBs
NCBI-GeneID:
100063339
NCBI-ProteinID:
XP_001504700
Ensembl:
ENSECAG00000024562
VGNC:
20815
UniProt:
F6REP3
LinkDB
All DBs
Position
4:102723960..102742262
Genome browser
AA seq
1204 aa
AA seq
DB search
MGNLKSVGQEPGPPCGLGLGLGLGLCGKQGPASPASEPSRAPVPAPAPAPLPAPDHSPPL
ARPPEGPKFPRVKNWEVGSITYDTLCAQSQQDGPCTPRRCLGSLVFPRKLQSRPSQGPPP
PEQLLSQARDFINQYYSSIKRSGSQAHEQRLQEVEAEVAATGTYQLRESELVFGAKQAWR
NAPRCVGRIQWGKLQVFDARDCSSAQEMFTCICNHIKYATNRGNLRSAITVFPQRTPGRG
DFRIWNSQLVRYAGYRQQDGSVRGDPANVEITELCVQHGWTPGNGRFDVLPLLLQAPDEP
PELFTLPPELVLEVPLEHPTLEWFASLGLRWYALPAVSNMLLEIGGLEFPAAPFSGWYMS
TEIGTRNLCDPHRYNILEDVAVCMDLDTRTTSSLWKDKAAVEINLAVLHSYQLAKVTIVD
HHAATASFMKHLENEQKARGGCPADWAWIVPPISGSLTPVFHQEMVNYVLSPAFRYQPDP
WKGSAVKGTGLARKKTFKEVANAVKISASLMGTVMAKRVKATILYGSETGRAQGYAQQLG
RLFRKAFDPRVLCMDEYDVVSLEHETLVLVVTSTFGNGDPPENGESFAAALMEMSGPYNS
SPRPEQHKSYKIRFNSVSCSDPLVSSWRRKRKESSNTDSAGALGTLRFCVFGLGSRAYPH
FCAFARAVDTRLEELGGERLLQLGQGDELCGQEEAFRGWAQAAFQASCETFCVGEDAKAA
ARDIFSPKRSWKRQRYRLSTQAEGLQLLPGLIHVHRRKMFQATVLSVENLQSSKSTRATI
LVRLDTGGQEGLQYQPGDHIGVCPPNRPGLVEALLSRVEDPPPAGEPVAVEQLEKGSPGG
PPPSWVRDPRLPPCTLRQALTFFLDITSPPSPQLLRLLSTLAEEPSEQQELETLSQDPRR
YEEWKWFRCPTLLEVLEQFPSVALPAALLLTQLPLLQPRYYSVSSAPSTHPGEIHLTVAV
LAYRTQDGLGPLHYGVCSTWLSQLKAGDLVPCFIRGAPSFRLPPDPSLPCILVGPGTGIA
PFRGFWQERLHDIESKGLQPAPMTLVFGCRCSQLDHLYRDEVQDAQQRGVFGRVLTAFSR
EPDSPKTYVQDILRTELAAEVHRVLCLDRGHMFVCGDVTMATSVLQTVQRILATEGDMEL
DEAGDVIGVLRDQQRYHEDIFGLTLRTQEVTSRIRTQSLSLHERHLQGTVPWAFDPPGPD
TSGR
NT seq
3615 nt
NT seq
+upstream
nt +downstream
nt
atgggcaacttgaagagtgtgggccaggagcctgggccaccctgcggcctggggctgggg
ctgggcctcgggctgtgtggcaagcagggcccagcctcccccgcatctgagcccagccgg
gcacctgtacccgcacccgcacccgcacccctgcctgcgccagaccacagccccccgctc
gccaggcccccagaggggcccaagttcccgcgtgtgaagaactgggaggtggggagcatc
acctacgacaccctgtgtgcccagtcccagcaggatgggccctgcaccccaagacgctgc
ctcggctccctggtgtttccacggaaactgcagagccggccgtcccagggccctccgcct
cctgagcagctgctgagtcaggctagggacttcatcaaccagtactacagctccatcaag
aggagcggctcccaggcccacgagcagcgtcttcaggaggtggaggccgaggtggcagcc
acgggcacctaccagcttcgggagagtgagctggtatttggggccaagcaggcctggcgc
aacgctccccgttgtgtgggccggatccagtgggggaaactgcaggtctttgatgcgcgg
gattgcagctctgcgcaggagatgttcacctgcatatgcaaccacatcaagtacgccacc
aaccggggcaaccttcgctctgccatcacagtgttcccccagcgcaccccgggccgcgga
gacttcagaatctggaacagccaactggtgcgctatgcaggctacagacagcaggacggc
tctgtgcggggggacccagccaacgtggagatcaccgagctctgcgtccagcatggctgg
actccaggaaatggccgctttgatgtgctgcccctgctgctccaggccccagatgaaccc
ccggaactcttcactctgccccccgagctggtgcttgaagtgcccctggagcaccccacg
ctggagtggttcgcatccctgggcctgcgctggtacgcgctcccggcagtgtccaacatg
ctgctggaaatcgggggcctggagttccctgcggcccctttcagcggctggtacatgagc
actgagatcggcacgcggaacctgtgtgaccctcaccgctacaacatcctggaggatgtg
gccgtctgcatggacttggataccaggacaacctcgtccctgtggaaagacaaggcagcg
gtggaaatcaacttggctgtgctgcacagttaccagctggccaaagtgaccattgtggac
caccacgccgccacagcctccttcatgaagcacctggagaatgagcagaaggcgaggggg
ggctgccctgccgactgggcctggattgtgccccccatctcgggcagcctcacccctgtc
ttccatcaggagatggtcaactatgtcctgtcccctgccttccgctaccagccagacccc
tggaaggggagtgcagtcaagggcaccggcctcgccaggaagaagacctttaaggaagtg
gccaatgctgtgaagatctctgcctccctcatgggcaccgtgatggcaaagagagtgaag
gctacaatcctgtacggctccgagaccggccgggcccagggctacgcacagcagctgggg
aggctcttccggaaggctttcgacccccgggtcctgtgcatggatgagtatgatgtggtg
tccctcgagcacgagacactggtgttggtggtgaccagcacattcgggaatggggatccc
ccagagaatggagagagtttcgcagcagccctgatggagatgtcgggcccttacaacagc
tcccctcggccagaacagcacaagagttacaaaatccgcttcaacagcgtctcctgttca
gacccactggtgtcctcctggcggcggaagagaaaggaatccagtaacacagacagtgca
ggggcactggggaccctcaggttctgtgtgttcgggctcggctcccgggcgtacccgcac
ttctgcgcctttgctcgtgcggtggacacgcggctggaagagctgggtggcgagcggctc
ctgcagctgggccagggagacgagctgtgcggccaggaggaggccttccgtggctgggcc
caagccgccttccaggcctcctgtgagaccttctgcgtgggagaggatgccaaggctgct
gcccgggacatattcagccccaaacggagctggaagcgccagaggtaccggctgagcacc
caggctgagggcctccagttgctaccaggcctgatccatgtgcaccggcgaaagatgttc
caggctacagtcctttcagtggaaaatctgcaaagcagcaagtccacccgggccacgatc
ctggtgcgcctggacactggaggccaggaggggctccagtaccagccaggggaccacata
ggcgtctgcccacccaaccggccgggactcgtggaggcactgctcagccgtgtggaggac
ccgccgccagcaggcgagcccgtggcagtggaacagctggagaagggcagccctggtggc
cctcccccaagctgggtgcgggacccccggctgcccccgtgcacgctgcgccaggctctc
accttcttcctggacatcacttccccgcccagccctcaactccttcgactgctcagcacc
ttggcagaagaacccagtgaacagcaggagcttgagaccctcagccaggacccccggcgc
tacgaagaatggaagtggttccgctgccccacgctgctggaggtgctggagcagtttcct
tcggtggcactgcctgctgccctgctcctcacccagctgcccctgctccagccccggtac
tactccgtcagctcagcccccagcacccacccaggagagatccacctcacagttgccgtg
ctggcatacaggacccaggatgggctaggccccctgcactatggagtctgctccacatgg
ctgagccaactcaaggccggagaccttgtaccctgcttcatcaggggggctccctccttc
cggctgcctccggaccccagcttgccctgcatcctggtgggccccggcacgggcatcgcc
cccttccggggattttggcaggagcggctgcatgacattgagagcaaagggctgcagccc
gcccccatgaccttggtgttcggctgccgatgctcccagctcgatcacctctaccgcgac
gaggtgcaggatgcccagcagcgcggggtatttggccgcgtcctcaccgccttctccagg
gaaccggacagccctaagacctacgtacaggacatcctgcggaccgagctggctgccgag
gtgcaccgcgtgctgtgcctcgatcggggccacatgtttgtctgcggtgatgtcaccatg
gcaaccagcgtcttgcagacggtgcaacgcatcctggcgacagagggcgacatggaactg
gacgaggccggcgacgtcatcggcgtgctgcgggatcagcaacgctatcacgaggacatt
ttcgggctcacgctgcgcacccaggaggtgacaagccgcatacgcacccagagcctttcc
ttgcacgagcggcatctgcagggcacagtgccctgggcgttcgacccgcccggcccagac
acctctggtcgctga
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integrated database retrieval system
