KEGG   Equus caballus (horse): 100063532
Entry
100063532         CDS       T01058                                 
Symbol
MAPK14
Name
(RefSeq) mitogen-activated protein kinase 14 isoform X1
  KO
K04441  p38 MAP kinase [EC:2.7.11.24]
Organism
ecb  Equus caballus (horse)
Pathway
ecb01522  Endocrine resistance
ecb04010  MAPK signaling pathway
ecb04015  Rap1 signaling pathway
ecb04068  FoxO signaling pathway
ecb04071  Sphingolipid signaling pathway
ecb04114  Oocyte meiosis
ecb04148  Efferocytosis
ecb04218  Cellular senescence
ecb04261  Adrenergic signaling in cardiomyocytes
ecb04370  VEGF signaling pathway
ecb04380  Osteoclast differentiation
ecb04550  Signaling pathways regulating pluripotency of stem cells
ecb04611  Platelet activation
ecb04613  Neutrophil extracellular trap formation
ecb04620  Toll-like receptor signaling pathway
ecb04621  NOD-like receptor signaling pathway
ecb04622  RIG-I-like receptor signaling pathway
ecb04625  C-type lectin receptor signaling pathway
ecb04657  IL-17 signaling pathway
ecb04658  Th1 and Th2 cell differentiation
ecb04659  Th17 cell differentiation
ecb04660  T cell receptor signaling pathway
ecb04664  Fc epsilon RI signaling pathway
ecb04668  TNF signaling pathway
ecb04670  Leukocyte transendothelial migration
ecb04714  Thermogenesis
ecb04722  Neurotrophin signaling pathway
ecb04723  Retrograde endocannabinoid signaling
ecb04728  Dopaminergic synapse
ecb04750  Inflammatory mediator regulation of TRP channels
ecb04912  GnRH signaling pathway
ecb04914  Progesterone-mediated oocyte maturation
ecb04917  Prolactin signaling pathway
ecb04926  Relaxin signaling pathway
ecb04932  Non-alcoholic fatty liver disease
ecb04933  AGE-RAGE signaling pathway in diabetic complications
ecb04935  Growth hormone synthesis, secretion and action
ecb04936  Alcoholic liver disease
ecb05014  Amyotrophic lateral sclerosis
ecb05020  Prion disease
ecb05022  Pathways of neurodegeneration - multiple diseases
ecb05132  Salmonella infection
ecb05133  Pertussis
ecb05135  Yersinia infection
ecb05140  Leishmaniasis
ecb05142  Chagas disease
ecb05145  Toxoplasmosis
ecb05152  Tuberculosis
ecb05161  Hepatitis B
ecb05163  Human cytomegalovirus infection
ecb05167  Kaposi sarcoma-associated herpesvirus infection
ecb05169  Epstein-Barr virus infection
ecb05170  Human immunodeficiency virus 1 infection
ecb05171  Coronavirus disease - COVID-19
ecb05205  Proteoglycans in cancer
ecb05208  Chemical carcinogenesis - reactive oxygen species
ecb05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
ecb05415  Diabetic cardiomyopathy
ecb05417  Lipid and atherosclerosis
ecb05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:ecb00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    100063532 (MAPK14)
   04015 Rap1 signaling pathway
    100063532 (MAPK14)
   04370 VEGF signaling pathway
    100063532 (MAPK14)
   04668 TNF signaling pathway
    100063532 (MAPK14)
   04068 FoxO signaling pathway
    100063532 (MAPK14)
   04071 Sphingolipid signaling pathway
    100063532 (MAPK14)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    100063532 (MAPK14)
  09143 Cell growth and death
   04114 Oocyte meiosis
    100063532 (MAPK14)
   04218 Cellular senescence
    100063532 (MAPK14)
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    100063532 (MAPK14)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    100063532 (MAPK14)
   04613 Neutrophil extracellular trap formation
    100063532 (MAPK14)
   04620 Toll-like receptor signaling pathway
    100063532 (MAPK14)
   04621 NOD-like receptor signaling pathway
    100063532 (MAPK14)
   04622 RIG-I-like receptor signaling pathway
    100063532 (MAPK14)
   04625 C-type lectin receptor signaling pathway
    100063532 (MAPK14)
   04660 T cell receptor signaling pathway
    100063532 (MAPK14)
   04658 Th1 and Th2 cell differentiation
    100063532 (MAPK14)
   04659 Th17 cell differentiation
    100063532 (MAPK14)
   04657 IL-17 signaling pathway
    100063532 (MAPK14)
   04664 Fc epsilon RI signaling pathway
    100063532 (MAPK14)
   04670 Leukocyte transendothelial migration
    100063532 (MAPK14)
  09152 Endocrine system
   04912 GnRH signaling pathway
    100063532 (MAPK14)
   04914 Progesterone-mediated oocyte maturation
    100063532 (MAPK14)
   04917 Prolactin signaling pathway
    100063532 (MAPK14)
   04926 Relaxin signaling pathway
    100063532 (MAPK14)
   04935 Growth hormone synthesis, secretion and action
    100063532 (MAPK14)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    100063532 (MAPK14)
  09156 Nervous system
   04728 Dopaminergic synapse
    100063532 (MAPK14)
   04723 Retrograde endocannabinoid signaling
    100063532 (MAPK14)
   04722 Neurotrophin signaling pathway
    100063532 (MAPK14)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    100063532 (MAPK14)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    100063532 (MAPK14)
  09159 Environmental adaptation
   04714 Thermogenesis
    100063532 (MAPK14)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    100063532 (MAPK14)
   05208 Chemical carcinogenesis - reactive oxygen species
    100063532 (MAPK14)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    100063532 (MAPK14)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    100063532 (MAPK14)
   05161 Hepatitis B
    100063532 (MAPK14)
   05171 Coronavirus disease - COVID-19
    100063532 (MAPK14)
   05163 Human cytomegalovirus infection
    100063532 (MAPK14)
   05167 Kaposi sarcoma-associated herpesvirus infection
    100063532 (MAPK14)
   05169 Epstein-Barr virus infection
    100063532 (MAPK14)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    100063532 (MAPK14)
   05135 Yersinia infection
    100063532 (MAPK14)
   05133 Pertussis
    100063532 (MAPK14)
   05152 Tuberculosis
    100063532 (MAPK14)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    100063532 (MAPK14)
   05140 Leishmaniasis
    100063532 (MAPK14)
   05142 Chagas disease
    100063532 (MAPK14)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    100063532 (MAPK14)
   05020 Prion disease
    100063532 (MAPK14)
   05022 Pathways of neurodegeneration - multiple diseases
    100063532 (MAPK14)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    100063532 (MAPK14)
   05418 Fluid shear stress and atherosclerosis
    100063532 (MAPK14)
   05415 Diabetic cardiomyopathy
    100063532 (MAPK14)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    100063532 (MAPK14)
   04932 Non-alcoholic fatty liver disease
    100063532 (MAPK14)
   04933 AGE-RAGE signaling pathway in diabetic complications
    100063532 (MAPK14)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    100063532 (MAPK14)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:ecb01001]
    100063532 (MAPK14)
Enzymes [BR:ecb01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     100063532 (MAPK14)
Protein kinases [BR:ecb01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   100063532 (MAPK14)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr ABC1 Kdo APH NAD_binding_8
Other DBs
NCBI-GeneID: 100063532
NCBI-ProteinID: XP_023480592
UniProt: A0A9L0RKD4
LinkDB
Position
20:36935291..37003038
AA seq 360 aa
MSQERPTFYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQ
SIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQ
KLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEMT
GYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVG
TPGAELLKKISSESARNYIQSLTQMPKMNFANVFIGANPLAVDLLEKMLVLDSDKRITAA
QALAHAYFAQYHDPDDEPVADPYDQSFESRDLLIDEWKSLTYDEVISFVPPPLDQEEMES
NT seq 1083 nt   +upstreamnt  +downstreamnt
atgtctcaggagaggcccaccttctaccggcaggagctgaacaagaccatttgggaggtg
cccgagcggtaccagaacctgtccccggtgggctccggcgcctatggctccgtgtgtgct
gcttttgacacaaaaactgggttacgtgtggcagtgaagaagctatccagaccgtttcag
tccattattcatgccaaaaggacctacagagaactacggttacttaaacacatgaaacat
gaaaatgtgattggtctgttggatgtttttacacctgcaaggtctctggaggaattcaat
gatgtgtatctggtgacccatctcatgggggcagatctgaacaacattgtgaaatgtcag
aagcttacagatgaccatgttcagtttcttatctaccaaattctccgaggtctcaagtat
atacattcagccgacataattcacagggacctaaaacctagtaatctagctgtgaatgaa
gactgcgagctgaagatcttggattttggactggctcgacatacagatgatgaaatgaca
ggctatgtggccactaggtggtacagggctcctgagatcatgctgaactggatgcattac
aaccagacagttgatatttggtcggtgggatgcataatggcggagctgttgactggaaga
acgttgtttcctggcacagaccatattgatcagttgaagctcattttaagactcgttgga
accccaggggctgagcttttgaagaaaatctcctcagagtctgcaagaaactacattcaa
tctttgacccagatgccaaagatgaactttgcaaatgtatttattggtgccaatcccttg
gctgtcgacttgctggagaagatgcttgtgttggactcagataagaggattacagcagca
caagcccttgcgcatgcctactttgctcagtaccacgatcctgacgatgaaccagtggct
gatccttacgatcagtcctttgaaagcagggacctccttatagatgaatggaaaagcctg
acctatgatgaagtcatcagctttgtgccaccaccccttgaccaagaagagatggaatcc
tga

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