Equus caballus (horse): 100064339
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Entry
100064339 CDS
T01058
Symbol
ERN1
Name
(RefSeq) serine/threonine-protein kinase/endoribonuclease IRE1
KO
K08852
serine/threonine-protein kinase/endoribonuclease IRE1 [EC:
2.7.11.1
3.1.26.-]
Organism
ecb
Equus caballus (horse)
Pathway
ecb04140
Autophagy - animal
ecb04141
Protein processing in endoplasmic reticulum
ecb04210
Apoptosis
ecb04932
Non-alcoholic fatty liver disease
ecb05010
Alzheimer disease
ecb05012
Parkinson disease
ecb05014
Amyotrophic lateral sclerosis
ecb05016
Huntington disease
ecb05017
Spinocerebellar ataxia
ecb05022
Pathways of neurodegeneration - multiple diseases
ecb05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
ecb00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
100064339 (ERN1)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
100064339 (ERN1)
09143 Cell growth and death
04210 Apoptosis
100064339 (ERN1)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
100064339 (ERN1)
05012 Parkinson disease
100064339 (ERN1)
05014 Amyotrophic lateral sclerosis
100064339 (ERN1)
05016 Huntington disease
100064339 (ERN1)
05017 Spinocerebellar ataxia
100064339 (ERN1)
05022 Pathways of neurodegeneration - multiple diseases
100064339 (ERN1)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
100064339 (ERN1)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
100064339 (ERN1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
ecb01001
]
100064339 (ERN1)
Enzymes [BR:
ecb01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
100064339 (ERN1)
Protein kinases [BR:
ecb01001
]
Serine/threonine kinases: Other
IRE family
100064339 (ERN1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
Ribonuc_2-5A
PK_Tyr_Ser-Thr
PQQ_2
PQQ
Pkinase_fungal
Kdo
APH
PQQ_3
Band_3_cyto
Motif
Other DBs
NCBI-GeneID:
100064339
NCBI-ProteinID:
XP_023507984
Ensembl:
ENSECAG00000011262
VGNC:
17673
UniProt:
F7BA63
LinkDB
All DBs
Position
11:15315432..15397334
Genome browser
AA seq
974 aa
AA seq
DB search
MPARLLLLLALLLPGPGIFGSPSTVTLPETLLFVSTLDGSLHAVSKRTGSIKWTLKEDPV
LQVPTHVEEPAFLPDPNDGSLYTLGGKNNEGLTKLPFTIPELVQASPCRSSDGILYMGKK
QDIWYVVDLLTGEKQQTLSSAFADSLCPSTSLLYLGRTEYTITMYDTKTRELRWNATYFD
YAASLPEDDMDYKMSHFVSNGDGLVVTVDSESGDVLWIQNYASPVVAFYVWQREGLRKVM
HINVAVETLRYLTFMSGEVGRITKWKYPFPKETEAKSKLTPTLYVGKYSTSLYASPSMVH
EGVAVVPRGSTLPLLEGPQTDGVTIGDKGECVITPSTDLKFDPGLKGKNKLNYLRNYWLL
IGHHETPLSASTKMLERFPNNLPKHRENVIPADSEKKSFEEVINLVDQTSESAPTTVSQE
VEEKFTHAPAKPEAPVDSMLKDIATIILSTFLLIGWVAFIITYPLSMHQQQQLQHQQFQK
ELEKIQLLQQQQLPFHPPGDVVQDTELLDSSGPYSESSATSSPSTSPRASNHSLHSTGSA
SKAGTSPFLEQDDEDEETSMVIVGKISFCPKDVLGHGAEGTIVYRGMFDNRDVAVKRILP
ECFSFADREVQLLRESDEHPNVIRYFCTERDRQFQYIAIELCAATLQEYVEQKDFAHLGL
EPITLLQQTTSGLAHLHSLNIVHRDLKPHNILLSMPNAHGRIKAMISDFGLCKKLAVGRH
SFSRRSGVPGTEGWIAPEMLSEDCKENPTYTVDIFSAGCVFYYVISEGSHPFGKSLQRQA
NILLGAYSLDCLHPEKHEDVIARELIEKMIAMDPQKRPSAKHVLKHPFFWSLEKQLQFFQ
DVSDRIEKESLDGPIVKQLERGGRAVVKMDWKENITVPLQTDLRKFRTYKGGSVRDLLRA
MRNKKHHYRELPVEVRETLGSLPDDFVRYFTSRFPHLLSHTYRAMELCRHERLFQPYYFH
EPPEPQPPVTPDAL
NT seq
2925 nt
NT seq
+upstream
nt +downstream
nt
atgccggcccggctgctgctgctactggcgctgctgctgcccggccccgggatttttgga
agtcccagcacagtgacgcttcctgaaaccttgttgtttgtgtcaacactggatggaagt
ttgcatgctgtcagcaagaggacaggctccatcaaatggactttaaaagaagatccagtt
ctgcaggttccaacacatgttgaagagcctgccttcctcccagatcccaacgatggcagc
ctctatacccttgggggcaagaataacgaaggcctgacgaaacttccctttaccatccca
gagttggtacaggcatccccatgccgaagttcagatggaattctctacatgggtaaaaag
caggacatttggtatgttgttgaccttctaaccggagagaagcagcagactttgtcatcg
gcgtttgcagatagtctctgcccatcaacctctcttctgtatcttgggcgaacagagtac
accatcaccatgtacgacaccaaaacccgtgagctccggtggaatgccacctacttcgac
tatgcagcctcactgcctgaggacgacatggactacaaaatgtcccactttgtgtccaat
ggtgatgggctggtggtgaccgtggacagtgaatctggcgatgtcctatggatccaaaac
tatgcttcccctgtggtggccttttatgtctggcagcgggagggtctgaggaaggtcatg
cacatcaacgttgctgtggagaccctgcgctatctgaccttcatgtctggggaggtgggg
cgcatcaccaagtggaagtaccctttccccaaggagacggaggccaagagcaagctgacg
cccaccctgtatgttgggaaatactctaccagcctctatgcctccccttcaatggtacac
gagggggtcgctgttgtgccccgaggcagcactcttcctttgctggaaggcccccagacc
gatggtgtcaccattggggacaaaggggagtgtgtgatcacacccagcacggacctaaag
tttgaccctgggctcaaagggaagaacaagctcaactacttgaggaactactggcttctg
ataggacaccatgaaaccccactgtctgcgtctactaagatgctggagagattccccaac
aatctgcccaaacatcgggaaaatgtgattcctgccgattcggagaaaaagagctttgag
gaagttatcaacctggttgaccaaacttcagaaagtgcgcctaccactgtttctcaggag
gtggaagagaagttcactcatgcccccgccaagcctgaggcccccgtggactccatgctc
aaggacatagccaccattatcctgagcaccttcctgctcatcggctgggtggccttcatc
atcacctaccccttaagcatgcatcagcagcagcagcttcagcaccaacagttccagaag
gaactggagaaaatccagctcctgcaacagcagcagctgcccttccacccacctggagat
gtggttcaggacaccgagctcctggactcatccggcccgtactcggagagctcagccacc
agcagccccagcacgtcccccagagcctccaaccactcgctccactctaccggctctgcc
tccaaggctggcaccagccccttcctggagcaggacgacgaggatgaggaaaccagcatg
gtgatagttgggaaaatttcattctgtcccaaggatgtcctgggccacggagcagagggc
acaattgtgtaccggggcatgtttgacaaccgcgacgtagcagtcaagaggatcctccct
gagtgtttcagtttcgcagaccgtgaggtccagctactgcgagaatcagacgagcacccg
aacgtgatccgttacttctgcactgagagggaccggcagttccagtacattgccattgag
ctgtgtgcagccactctgcaggagtacgtggagcagaaggactttgcccacctcggcctg
gagcccatcaccttgctgcagcagaccacctcgggcctggcccacctgcactccctcaac
attgttcacagagacctgaagcctcacaacattctcctctccatgcccaacgcacatggc
aggatcaaggccatgatctccgacttcggcctctgcaagaaactggccgtgggcaggcat
agcttcagccgccgttcaggagtgcctggcacagaaggctggatcgctccggagatgctg
agcgaagactgcaaggaaaaccctacctacaccgtggacatcttctctgctggctgtgtc
ttttactacgtgatatctgagggcagccacccttttgggaagtccctgcagcggcaggcc
aacatcctcctgggtgcctacagcctcgactgcttacaccccgagaagcatgaagatgtc
attgcccgagaattaatagagaagatgattgcaatggatcctcagaagcgcccctcagcg
aagcatgtgctgaaacacccgttcttctggagcctagaaaagcagctccagttctttcag
gacgtcagtgaccggatagaaaaggaatccctggacggcccgatagtgaagcagctggag
agaggtgggagagctgtggtgaagatggactggaaggagaacatcactgtccccctccag
acggatctgcgtaaattcagaacctataaaggtggctcggtcagggatctcctccgagcc
atgagaaataagaagcaccactaccgggagctgcctgtggaggtgcgggagacgctgggc
tccctgcccgacgacttcgtgcgctacttcacctcgcgcttcccccacctcctctcacac
acctaccgggccatggagctgtgccgccatgagagactcttccagccctactacttccac
gagcccccggagccccagcccccagtgactccagatgccctctga
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