Equus caballus (horse): 100064403
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Entry
100064403 CDS
T01058
Symbol
ATP2A1
Name
(RefSeq) sarcoplasmic/endoplasmic reticulum calcium ATPase 1 isoform X2
KO
K05853
P-type Ca2+ transporter type 2A [EC:
7.2.2.10
]
Organism
ecb
Equus caballus (horse)
Pathway
ecb04020
Calcium signaling pathway
ecb04022
cGMP-PKG signaling pathway
ecb04024
cAMP signaling pathway
ecb04148
Efferocytosis
ecb04260
Cardiac muscle contraction
ecb04261
Adrenergic signaling in cardiomyocytes
ecb04380
Osteoclast differentiation
ecb04919
Thyroid hormone signaling pathway
ecb04972
Pancreatic secretion
ecb05010
Alzheimer disease
ecb05017
Spinocerebellar ataxia
ecb05022
Pathways of neurodegeneration - multiple diseases
ecb05410
Hypertrophic cardiomyopathy
ecb05412
Arrhythmogenic right ventricular cardiomyopathy
ecb05414
Dilated cardiomyopathy
ecb05415
Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
ecb00001
]
09130 Environmental Information Processing
09132 Signal transduction
04020 Calcium signaling pathway
100064403 (ATP2A1)
04024 cAMP signaling pathway
100064403 (ATP2A1)
04022 cGMP-PKG signaling pathway
100064403 (ATP2A1)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
100064403 (ATP2A1)
09150 Organismal Systems
09152 Endocrine system
04919 Thyroid hormone signaling pathway
100064403 (ATP2A1)
09153 Circulatory system
04260 Cardiac muscle contraction
100064403 (ATP2A1)
04261 Adrenergic signaling in cardiomyocytes
100064403 (ATP2A1)
09154 Digestive system
04972 Pancreatic secretion
100064403 (ATP2A1)
09158 Development and regeneration
04380 Osteoclast differentiation
100064403 (ATP2A1)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
100064403 (ATP2A1)
05017 Spinocerebellar ataxia
100064403 (ATP2A1)
05022 Pathways of neurodegeneration - multiple diseases
100064403 (ATP2A1)
09166 Cardiovascular disease
05410 Hypertrophic cardiomyopathy
100064403 (ATP2A1)
05412 Arrhythmogenic right ventricular cardiomyopathy
100064403 (ATP2A1)
05414 Dilated cardiomyopathy
100064403 (ATP2A1)
05415 Diabetic cardiomyopathy
100064403 (ATP2A1)
Enzymes [BR:
ecb01000
]
7. Translocases
7.2 Catalysing the translocation of inorganic cations
7.2.2 Linked to the hydrolysis of a nucleoside triphosphate
7.2.2.10 P-type Ca2+ transporter
100064403 (ATP2A1)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
E1-E2_ATPase
Cation_ATPase_C
Cation_ATPase
Cation_ATPase_N
Hydrolase
Hydrolase_3
HAD
Motif
Other DBs
NCBI-GeneID:
100064403
NCBI-ProteinID:
XP_001502312
Ensembl:
ENSECAG00000012593
VGNC:
15650
UniProt:
A0A5F5PNX8
LinkDB
All DBs
Position
13:20994033..21009754
Genome browser
AA seq
993 aa
AA seq
DB search
MEAAHSKTTEECLAYFGVSETAGLTPEQVKRHLEKYGPNELPTEEGKSLWELVVEQFEDL
LVRILLLAACISFVLAWFEEGEETVTAFVEPFVILLILIANAIVGVWQERNAENAIEALK
EYEPEMGKVYRADRKSVQRIKARDIVPGDIVEVAVGDKVPADIRILSIKSTTLRVDQSIL
TGESVSVIKHTEPVPDPRAVNQDKKNMLFSGTNIAAGKALGIVAATGVNTEIGKIRDQMA
ATEQDKTPLQQKLDEFGEQLSKVISLICVAVWLINIGHFNDPVHGGSWLRGAIYYFKIAV
ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ
MSVCKMFIVDKVDGDLCILNEFSITGSTYAPEGEILKNDKPVRAGQYDGLVEVATICALC
NDSSLDFNEAKGVYEKVGEATETALTTLVEKMNVFNTDVRNLSKVERANACNSVIRQLMK
KEFTLEFSRDRKSMSVYCSPAKSRAAVGNKMFVKGAPEGVLDRCNYVRVGTTRVPMAGPV
KERILSVIKEWGTGRDTLRCLALATRDTPPKREDMILDDSARFMEYETDLTFIGVVGMLD
PPRKEVTGSIQLCRDAGIRVIMITGDNKGTAIAICRRIGIFGENEEVADRAYTGREFDDL
PLAEQREACRRACCFARVEPSHKSKIVEYLQSFDEITAMTGDGVNDAPALKKAEIGIAMG
SGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAAL
GLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMDRPPRSPKEPLISGWLFFRYMAIG
GYVGAATVGAAAWWFLFAEDGPHVTYSQLTHFMKCNEHNPDFEGVDCEVFEAPEPMTMAL
SVLVTIEMCNALNSLSENQSLVRMPPWVNIWLVGSICLSMSLHFLILYVDPLPMIFKLEA
LDLTHWLMVLKISFPVILLDEVLKFVARNYLEG
NT seq
2982 nt
NT seq
+upstream
nt +downstream
nt
atggaggctgcacactccaagaccacagaagaatgtttggcctattttggggtgagcgag
actgctggcctcaccccggaacaagttaagcggcatctggagaaatacggccccaatgag
ctccctactgaggaagggaagtccctgtgggagttggtggtagagcagtttgaagacctc
ctggtgcggatccttctcctggctgcctgcatttcctttgtgctggcctggttcgaggaa
ggtgaagagaccgtcactgcctttgttgaaccctttgtcatcctcttgatcctcattgcc
aacgccattgtgggggtttggcaggagcgtaatgcagagaacgccattgaggctctgaag
gaatatgaacccgaaatgggaaaggtctaccgggctgaccgcaagtcagtgcaaaggatc
aaggctcgggacattgtccctggggacattgtggaagtggctgtgggagacaaagtccct
gcagatatccgcatcctctccatcaaatctaccaccctgcgggttgaccagtccatcctg
acaggcgagtctgtatccgtcatcaagcacacagaacctgttcctgacccccgagctgtc
aaccaggacaagaagaacatgcttttctcgggcaccaacattgcagccggcaaggccttg
ggcattgtggccgccactggggtgaacacggagattgggaagatccgtgaccagatggcc
gccacggaacaagacaaaaccccgctgcagcagaagctggatgagttcggggagcagctc
tccaaggtcatctccctcatctgtgtggctgtctggctcatcaacattggccacttcaat
gacccagtccacgggggctcctggttgcgtggcgccatctactacttcaagattgctgtg
gccctggctgtcgctgcaatcccagaaggccttcctgcagtcatcaccacctgcctggcc
ttgggtacccgccggatggcaaagaaaaatgcgatcgtgaggagcttgccctctgtagag
acgctgggctgcacctctgtcatctgttccgacaagacaggcaccctcaccaccaaccag
atgtctgtctgcaagatgtttatcgtcgacaaggtggatggggacctctgcattctgaac
gagttttctatcactggctccacttatgctccggaaggggagatcttgaagaatgataag
ccagtccgggcagggcagtatgatgggctagtggaggtggccaccatttgtgccctctgc
aatgactcctccttggacttcaatgaggccaaaggtgtctatgagaaggtaggtgaggcc
actgagacggcactcaccaccctggtggagaagatgaatgtattcaacactgatgtgaga
aacctctcgaaggtggagagagccaatgcctgcaactcagtcatccgccagctaatgaag
aaggaattcaccctggagttctcccgagacagaaagtccatgtctgtctattgctccccc
gccaaatcccgggctgctgtgggcaacaagatgtttgtcaagggtgcccctgagggggtc
ctcgaccgttgtaactatgtgcgagttggcaccacccgggtgcccatggcagggcccgtg
aaggaaaggatcttgtcggtgatcaaggagtggggcactggccgggacaccctgcgctgc
ttggccctggctacccgggacacccccccaaagcgagaggatatgattctggatgactct
gccaggttcatggagtacgagacggacctgaccttcattggcgtggtgggcatgttggac
ccgccccgcaaggaggtcacaggctctatccagctgtgccgcgatgcgggaatccgagtg
atcatgatcactggggacaacaagggcacagccattgccatctgccgacgaatcggcatc
tttggggagaatgaggaggtggctgacagggcctacacgggccgggagttcgacgacctg
cccctggccgagcagagggaggcctgccgccgtgcttgctgctttgcccgtgtggagcct
tcccataagtccaagatcgtggagtatctgcagtcctttgacgagatcacggctatgacc
ggtgatggcgtcaacgatgcccccgccctgaagaaggcagaaatcggcattgccatgggc
tctggcactgctgtggccaagaccgcctcggagatggtgctggcggacgacaacttctcc
accatcgtggctgcggtggaggagggccgggccatctacaacaacatgaagcagttcatc
cgctacctcatctcctccaacgtgggcgaggtggtctgcatcttcctgacagcagccttg
gggctgcctgaggccctgatccccgtgcagctgctgtgggtgaacttggtaactgatggg
ctcccggccacagccctgggcttcaacccaccggacctggacatcatggaccggcccccc
cggagccccaaggagcccctcatcagtggctggctcttcttccgctacatggcaattggg
ggctacgtgggtgcagccactgtgggagcagctgcctggtggttcttatttgctgaagat
gggcctcatgtcacctatagccagctgactcacttcatgaagtgcaatgaacacaacccc
gactttgagggtgtggattgtgaggtctttgaggccccggagccaatgaccatggccttg
tctgtgctggttaccatcgagatgtgcaatgctctcaacagcctgtctgagaaccagtcc
ctcgtgcggatgccaccctgggtgaacatctggctggtgggctccatctgcctctccatg
tccctccatttcctcatcctctacgtcgaccctctgccgatgatcttcaagctcgaggcc
ctggacctcacccattggctcatggtcctcaagatctcatttccagtcattttgctcgat
gaagtcctcaagttcgtcgctcggaactatctggagggataa
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